Polyglyceryl-2 Isostearate

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  • Identifiers

    CAS number
    81752-33-2

    Molecular formula
    C24H48O6

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)OCC(COCC(CO)O)O

  • Odor profile

    Fragrance
    Waxy 56.76%
    Fatty 43.12%
    Odorless 42.75%
    Oily 36.58%
    Alcoholic 25.07%
    Buttery 21.03%
    Milky 19.32%
    Sweet 19.14%
    Creamy 19.06%
    Lactonic 17.95%

     

    Flavor
    Waxy 42.21%
    Mild 39.37%
    Bland 35.34%
    Odorless 35.03%
    Fatty 34.31%
    Oily 32.1%
    Faint 24.31%
    Slightly waxy 22.6%
    Soapy 22.37%
    Bay oil 22.2%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.4

    pKa est.
    7.42 (neutral)

    Molecular weight
    432.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    618°C

    Flash point

    • 227.12 ˚C est.

  • Synonyms

    • Diglycerin monoisostearate
    • 7B8OE71MQC
    • 81752-33-2
    • UNII-7B8OE71MQC
    • Isooctadecanoic acid, monoester with oxybis(propanediol)
    • [3-(2,3-dihydroxypropoxy)-2-hydroxypropyl] 16-methylheptadecanoate
    • Isooctadecanoic acid, monoester with oxybis[propanediol]
    • DTXSID80994014
    • WVRJNKBXUMGBGG-UHFFFAOYSA-N
    • Q27268012
    • 3-(2,3-DIHYDROXYPROPOXY)-2-HYDROXYPROPYL 16-METHYLHEPTADECANOATE
    • 685-535-3

  • Applications

    Polyglyceryl-2 Isostearate (CAS 81752-33-2) is commonly used as a non-ionic surfactant and emulsifier in cosmetics and personal care, helping to form and stabilize oil-in-water emulsions and often serving as a conditioning emollient. It also acts as a fragrance solubilizer in perfumery and fragrance-containing formulations, aiding the dispersion of essential oils and aroma compounds. In cleaning and household products, it provides mild surfactant properties to improve wetting, cleansing performance, and formulation stability. In coatings and inks, it functions as a dispersant/emulsifier for pigments and binders in water-based systems, improving pigment stability and gloss. In polymers and plastics, it can serve as a processing aid and lubricity modifier, improving compatibility with hydrophobic components and aiding melt processing. It may also be used as an excipient/emulsifier in pharmaceutical topical formulations, subject to regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.54
    methanol 6.5
    isopropanol 1.52
    water 0.25
    ethyl acetate 5.02
    n-propanol 2.87
    acetone 8.1
    n-butanol 2.69
    acetonitrile 2.03
    DMF 25.22
    toluene 3.03
    isobutanol 2.53
    1,4-dioxane 11.56
    methyl acetate 5.58
    THF 39.61
    2-butanone 8.85
    n-pentanol 3.61
    sec-butanol 2.75
    n-hexane 0.38
    ethylene glycol 1.13
    NMP 80.96
    cyclohexane 1.42
    DMSO 70.12
    n-butyl acetate 6.76
    n-octanol 7.13
    chloroform 21.71
    n-propyl acetate 8.71
    acetic acid 16.97
    dichloromethane 21.37
    cyclohexanone 35.5
    propylene glycol 2.51
    isopropyl acetate 6.32
    DMAc 65.51
    2-ethoxyethanol 15.48
    isopentanol 3.78
    n-heptane 0.61
    ethyl formate 5.69
    1,2-dichloroethane 13.33
    n-hexanol 2.94
    2-methoxyethanol 15.35
    isobutyl acetate 7.11
    tetrachloromethane 5.17
    n-pentyl acetate 19.18
    transcutol 106.37
    n-heptanol 6.35
    ethylbenzene 2.95
    MIBK 8.52
    2-propoxyethanol 12.35
    tert-butanol 4.07
    MTBE 4.97
    2-butoxyethanol 24.47
    propionic acid 8.24
    o-xylene 4.51
    formic acid 9.69
    diethyl ether 2.08
    m-xylene 3.19
    p-xylene 3.85
    chlorobenzene 4.68
    dimethyl carbonate 5.64
    n-octane 0.48
    formamide 13.08
    cyclopentanone 40.7
    2-pentanone 7.63
    anisole 6.63
    cyclopentyl methyl ether 16.99
    gamma-butyrolactone 41.39
    1-methoxy-2-propanol 14.08
    pyridine 11.04
    3-pentanone 7.78
    furfural 37.35
    n-dodecane 0.35
    diethylene glycol 8.83
    diisopropyl ether 1.68
    tert-amyl alcohol 6.23
    acetylacetone 18.2
    n-hexadecane 0.4
    acetophenone 14.52
    methyl propionate 7.27
    isopentyl acetate 9.63
    trichloroethylene 31.67
    n-nonanol 7.43
    cyclohexanol 8.24
    benzyl alcohol 7.04
    2-ethylhexanol 3.86
    isooctanol 6.73
    dipropyl ether 4.32
    1,2-dichlorobenzene 7.84
    ethyl lactate 10.72
    propylene carbonate 23.27
    n-methylformamide 9.73
    2-pentanol 2.13
    n-pentane 0.24
    1-propoxy-2-propanol 13.2
    1-methoxy-2-propyl acetate 15.11
    2-(2-methoxypropoxy) propanol 26.49
    mesitylene 2.7
    ε-caprolactone 35.7
    p-cymene 3.2
    epichlorohydrin 33.31
    1,1,1-trichloroethane 13.53
    2-aminoethanol 2.95
    morpholine-4-carbaldehyde 48.47
    sulfolane 126.58
    2,2,4-trimethylpentane 0.64
    2-methyltetrahydrofuran 17.93
    n-hexyl acetate 19.91
    isooctane 0.31
    2-(2-butoxyethoxy)ethanol 35.37
    sec-butyl acetate 7.91
    tert-butyl acetate 15.31
    decalin 1.24
    glycerin 7.46
    diglyme 73.88
    acrylic acid 8.54
    isopropyl myristate 5.88
    n-butyric acid 12.45
    acetyl acetate 7.09
    di(2-ethylhexyl) phthalate 8.91
    ethyl propionate 7.43
    nitromethane 26.28
    1,2-diethoxyethane 15.25
    benzonitrile 6.16
    trioctyl phosphate 6.46
    1-bromopropane 4.09
    gamma-valerolactone 67.53
    n-decanol 4.47
    triethyl phosphate 10.61
    4-methyl-2-pentanol 2.57
    propionitrile 2.17
    vinylene carbonate 18.28
    1,1,2-trichlorotrifluoroethane 53.38
    DMS 11.2
    cumene 2.98
    2-octanol 4.99
    2-hexanone 9.73
    octyl acetate 8.38
    limonene 4.97
    1,2-dimethoxyethane 25.73
    ethyl orthosilicate 10.45
    tributyl phosphate 8.15
    diacetone alcohol 24.77
    N,N-dimethylaniline 8.4
    acrylonitrile 3.5
    aniline 4.68
    1,3-propanediol 4.7
    bromobenzene 5.02
    dibromomethane 10.73
    1,1,2,2-tetrachloroethane 35.66
    2-methyl-cyclohexyl acetate 14.15
    tetrabutyl urea 12.68
    diisobutyl methanol 3.18
    2-phenylethanol 6.54
    styrene 2.7
    dioctyl adipate 14.65
    dimethyl sulfate 23.97
    ethyl butyrate 9.13
    methyl lactate 10.4
    butyl lactate 22.89
    diethyl carbonate 5.92
    propanediol butyl ether 25.5
    triethyl orthoformate 12.39
    p-tert-butyltoluene 3.34
    methyl 4-tert-butylbenzoate 28.88
    morpholine 18.63
    tert-butylamine 2.14
    n-dodecanol 2.82
    dimethoxymethane 11.99
    ethylene carbonate 14.7
    cyrene 35.06
    2-ethoxyethyl acetate 26.91
    2-ethylhexyl acetate 8.14
    1,2,4-trichlorobenzene 11.63
    4-methylpyridine 8.96
    dibutyl ether 7.42
    2,6-dimethyl-4-heptanol 3.18
    DEF 17.34
    dimethyl isosorbide 53.03
    tetrachloroethylene 24.12
    eugenol 25.92
    triacetin 37.31
    span 80 23.04
    1,4-butanediol 3.04
    1,1-dichloroethane 7.41
    2-methyl-1-pentanol 5.0
    methyl formate 7.89
    2-methyl-1-butanol 4.12
    n-decane 0.82
    butyronitrile 2.46
    3,7-dimethyl-1-octanol 6.65
    1-chlorooctane 4.43
    1-chlorotetradecane 1.23
    n-nonane 0.72
    undecane 0.5
    tert-butylcyclohexane 0.92
    cyclooctane 0.64
    cyclopentanol 8.83
    tetrahydropyran 11.49
    tert-amyl methyl ether 7.16
    2,5,8-trioxanonane 44.95
    1-hexene 1.19
    2-isopropoxyethanol 12.65
    2,2,2-trifluoroethanol 12.15
    methyl butyrate 12.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction