Polydatin

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  • Identifiers

    CAS number
    27208-80-6

    Molecular formula
    C20H22O8

    SMILES
    C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Properties

    XLogP3-AA
    1.7

    Molecular weight
    390.4 g/mol

    Melting point expt.

    • 130 - 140 °C

  • Synonyms

    • Piceid
    • Trans-Piceid
    • 27208-80-6
    • 3,4,5-Trihydroxystilbene-3-beta-monoglucoside
    • 3,4,5-Tsg
    • Resveratrol 3-beta-mono-D-glucoside
    • Resveratrol 3-O-beta-glucopyranoside
    • XM261C37CQ
    • 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside
    • resveratrol 3-O-beta-D-glucoside
    • trans-resveratrol 3-beta-glucoside
    • trans-resveratrol 3-beta-D-glucoside
    • trans-resveratrol 3-O-beta-D-glucoside
    • CHEBI:8198
    • 3,4',5-trihydroxystilbene-3-beta-D-glucoside
    • 3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside
    • beta-D-Glucopyranoside, 3-hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl
    • Polydatin (E)-
    • polydatin, (E)-
    • RefChem:58805
    • Sooryehan Pure-Whitening
    • resveratrol-3-O-glucoside
    • Sooryehan Pure-Whitening Essence
    • Sooryehan Pure Whitening Spot Treatment
    • 5,4'-dihydroxystilbene-3-O-beta-D-Glcp
    • 65914-17-2
    • (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-(4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • MFCD00210592
    • Resveratrol 3-O-glucoside
    • (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • (2S,3R,4S,5S,6R)-2-(3-hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • MLS001424114
    • 3,5,4'-Trihydroxystilbene 3-glucoside
    • SMR000466371
    • b-D-Glucopyranoside, 3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl
    • (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
    • (E/Z)-Piceid
    • Resveratrol 3-Glucoside
    • 5-Tsg
    • trans Resveratrol 3-O-b-D-glucopyranoside, 98%
    • picied
    • UNII-XM261C37CQ
    • E/Z-Polydatin
    • resveratrol-3-O-beta-d-glucopyranoside
    • E/Z-Piceid
    • (2S,3R,4S,5S,6R)-2-[3-Hydroxy-5-[(E)-4-hydroxystyryl]phenoxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    • Resveratrol glucoside
    • (E)-Piceid
    • 5-Trihydroxystilbene-3-beta-monoglucoside
    • 3-Hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-glucopyranoside
    • Resveratrol 5-O-glucoside
    • SCHEMBL41411
    • MLS000759499
    • trans-Resveratrol 3-glucoside
    • E-resveratrol 3-beta-glucoside
    • CHEMBL142652
    • orb1304822
    • Resveratrol 3-beta-D-glucoside
    • SCHEMBL29355763
    • trans-Resveratrol 3-O-glucoside
    • BDBM60919
    • CHEBI:94610
    • cid_5281718
    • Reservatrol-3-b-mono-D-glucoside
    • resveratrol-3-O-beta-D-glucoside
    • DTXSID001030555
    • HMS2051A20
    • HMS6019I03
    • BB_NC-01425
    • HY-N0120
    • MSK40284
    • Resveratrol 3-O-b-D-glucopyranoside
    • resveratrol-3-O-b-mono-D-glucoside
    • EBC-26914
    • LMPK13090012
    • s2390
    • AKOS015961013
    • CCG-100895
    • DB11263
    • KS-5384
    • MT06138
    • NC00145
    • Resveratrol 3-.beta.-mono-d-glucoside
    • NCGC00246971-01
    • NCGC00246971-04
    • NCGC00246971-10
    • NCGC00246971-11
    • (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5-triol
    • AS-13910
    • DA-69167
    • SY056143
    • trans-resveratrol 3-beta-d-glucopyranoside
    • trans-resveratrol-3-beta-D-glucopyranoside
    • CS-0007830
    • NS00069817
    • AB00639953-07
    • EN300-7416763
    • 3,4',5-Trihydroxystilbene-3-b-D-glucopyranoside
    • 914P172
    • 5,4'-dihydroxystilbene-3-O-beta-D-glucopyranoside
    • Q3902665
    • RESVERATROL 3-.BETA.-MONO-D-GLUCOSIDE [MI]
    • 3,5,4'-trihydroxystilbene 3-O-beta-D-glucopyranoside
    • BRD-K43236057-001-07-1
    • 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside, 97%
    • 3,4'-5-TRIHYDROXYSTILBENE-3-.BETA.-D-GLUCOPYRANOSIDE
    • 3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl-beta-D-glucopyranoside
    • 3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-glucopyranoside
    • GLUCOPYRANOSIDE, 3-HYDROXY-5-(P-HYDROXYSTYRYL)PHENYL, .BETA.-D-
    • .BETA.-D-GLUCOPYRANOSIDE, 3-HYDROXY-5-((1E)-2-(4-HYDROXYPHENYL)ETHENYL)PHENYL
    • .BETA.-D-GLUCOPYRANOSIDE, 3-HYDROXY-5-(2-(4-HYDROXYPHENYL)ETHENYL)PHENYL
    • 5-((1E)-2-(4-HYDROXYPHENYL)ETHENYL)-1,3-BENZENEDIOL-3-.BETA.-MONO-D-GLUCOSIDE
    • beta-D-Glucopyranoside, 3-hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-, (E)-
    • (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-oxidanyl-phenoxy]oxane-3,4,5-triol
    • (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-methylol-tetrahydropyran-3,4,5-triol
    • .beta.-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl3,5,4'-Trihydroxystilbene 3-glucoside
    • 65914-17-2

  • Applications

    Polydatin (CAS 27208-80-6) is a glycosylated stilbenoid found in certain plants such as Polygonum cuspidatum. In industrial and consumer formulations, it is primarily used as a natural antioxidant and bioactive ingredient in cosmetics and personal care; it is commonly evaluated for inclusion in nutraceuticals and functional foods; it is studied as a bioactive glycoside with potential in pharmaceutical research; it can serve as a natural precursor or material in the synthesis of resveratrol derivatives in chemical manufacturing; and it is explored as a plant defense elicitor in agriculture. All uses are subject to local regulations and formulation limits.

    gpt-5-nano

1 3

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction