Phosphorus tribromide

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  • Identifiers

    CAS number
    7789-60-8

    Molecular formula
    Br3P

    SMILES
    P(Br)(Br)Br

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 58.21%
    Fishy 44.84%
    Ripe 23.7%
    Cheesy 21.94%
    Meaty 20.2%
    Sulfurous 18.57%
    Savory 18.11%
    Sweet 17.39%
    Cooked 15.03%
    Animal 14.18%

     

    Flavor
    Odorless 34.06%
    Sulfury 26.36%
    Sulfurous 25.48%
    Meaty 24.25%
    Fishy 23.01%
    Ammoniacal 18.94%
    Glue 18.72%
    Bloody 18.67%
    Rotten 18.49%
    Onion 18.4%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.8

    pKa est.
    -27.01 (strong acid)

    Molecular weight
    270.69 g/mol

    Melting point expt.

    • -42.9 °F (USCG, 1999)
    • -41.5 °C

    Boiling point

    • 343 °F at 760 mmHg (USCG, 1999)
    • 173.2 °C

    Flash point

    • 88.54 ˚C est.

    Solubility expt.

    • Reacts with water, ethanol; soluble in acetone, carbon disulfide
    • Soluble in acetone, alcohol, carbon disulfide, hydrogen sulfide, water (decomposes)

  • Synonyms

    • PHOSPHORUS TRIBROMIDE
    • 7789-60-8
    • Phosphorus(III) bromide
    • Phosphorous tribromide
    • Tribromophosphine
    • Phosphorous bromide
    • tribromophosphane
    • Phosphorus bromide
    • PBr3
    • Phosphorus bromide (PBr3)
    • HSDB 1217
    • Tribromo phosphine
    • EINECS 232-178-2
    • UN1808
    • UNII-58R3866PUA
    • 58R3866PUA
    • phosphorus (III) bromide
    • DTXSID7064869
    • PHOSPHORUS TRIBROMIDE [MI]
    • PHOSPHORUS TRIBROMIDE [HSDB]
    • MFCD00011436
    • UN 1808
    • PHOSPHORUS BROMIDE [PBR3]
    • Br3P
    • tribro-mophosphine
    • tribromo-phosphine
    • phosphorous tribromid
    • phosphorus(III)bromide
    • tris(bromanyl)phosphane
    • Phosphorus(III) tribromide
    • Phosphorus tribromide, 97%
    • Phosphorus tribromide, 99%
    • DTXCID3048073
    • BCP28228
    • AKOS015856778
    • P1743
    • Phosphorus tribromide [UN1808] [Corrosive]
    • A839279
    • Q416401
    • Phosphorus tribromide, >=99.99% trace metals basis
    • 232-178-2

  • Applications

    Phosphorus tribromide (CAS 7789-60-8) is primarily used in organic synthesis as a brominating and acylating agent. It converts alcohols to corresponding alkyl bromides and carboxylic acids to acyl bromides, providing reactive intermediates for downstream chemistry. In practice, it serves as a key reagent in pharmaceutical synthesis for introducing bromide or acyl functionalities, in polymers/plastics for functionalizing resin systems or preparing brominated monomers, and in coatings/inks for resin modification via acyl bromide intermediates. It is also employed in general industrial manufacturing as a versatile reagent in synthetic routes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 237.79
    methanol 229.05
    isopropanol 236.41
    water 9.86
    ethyl acetate 198.63
    n-propanol 200.59
    acetone 319.44
    n-butanol 223.98
    acetonitrile 119.2
    DMF 560.24
    toluene 178.94
    isobutanol 162.91
    1,4-dioxane 425.33
    methyl acetate 169.48
    THF 851.3
    2-butanone 216.93
    n-pentanol 171.16
    sec-butanol 197.05
    n-hexane 105.78
    ethylene glycol 101.14
    NMP 505.43
    cyclohexane 130.65
    DMSO 631.53
    n-butyl acetate 174.07
    n-octanol 172.15
    chloroform 394.55
    n-propyl acetate 153.84
    acetic acid 190.6
    dichloromethane 336.33
    cyclohexanone 304.12
    propylene glycol 119.83
    isopropyl acetate 188.16
    DMAc 408.21
    2-ethoxyethanol 261.21
    isopentanol 192.34
    n-heptane 104.68
    ethyl formate 148.91
    1,2-dichloroethane 252.14
    n-hexanol 207.23
    2-methoxyethanol 433.48
    isobutyl acetate 124.67
    tetrachloromethane 168.36
    n-pentyl acetate 186.62
    transcutol 387.75
    n-heptanol 173.88
    ethylbenzene 110.39
    MIBK 210.3
    2-propoxyethanol 340.32
    tert-butanol 295.65
    MTBE 264.18
    2-butoxyethanol 254.68
    propionic acid 134.95
    o-xylene 145.5
    formic acid 91.02
    diethyl ether 306.48
    m-xylene 165.5
    p-xylene 128.17
    chlorobenzene 169.06
    dimethyl carbonate 158.83
    n-octane 70.21
    formamide 140.46
    cyclopentanone 410.08
    2-pentanone 265.26
    anisole 200.04
    cyclopentyl methyl ether 411.68
    gamma-butyrolactone 388.77
    1-methoxy-2-propanol 407.08
    pyridine 253.34
    3-pentanone 195.99
    furfural 350.8
    n-dodecane 53.24
    diethylene glycol 286.15
    diisopropyl ether 179.65
    tert-amyl alcohol 221.19
    acetylacetone 298.89
    n-hexadecane 57.64
    acetophenone 174.36
    methyl propionate 199.87
    isopentyl acetate 159.77
    trichloroethylene 330.05
    n-nonanol 162.26
    cyclohexanol 244.33
    benzyl alcohol 155.36
    2-ethylhexanol 145.4
    isooctanol 149.26
    dipropyl ether 217.88
    1,2-dichlorobenzene 165.54
    ethyl lactate 113.59
    propylene carbonate 227.84
    n-methylformamide 211.56
    2-pentanol 206.35
    n-pentane 127.51
    1-propoxy-2-propanol 274.65
    1-methoxy-2-propyl acetate 214.54
    2-(2-methoxypropoxy) propanol 201.89
    mesitylene 141.4
    ε-caprolactone 260.16
    p-cymene 103.12
    epichlorohydrin 402.1
    1,1,1-trichloroethane 270.3
    2-aminoethanol 142.19
    morpholine-4-carbaldehyde 454.76
    sulfolane 539.52
    2,2,4-trimethylpentane 71.82
    2-methyltetrahydrofuran 451.11
    n-hexyl acetate 206.14
    isooctane 73.38
    2-(2-butoxyethoxy)ethanol 261.59
    sec-butyl acetate 128.84
    tert-butyl acetate 247.17
    decalin 72.36
    glycerin 177.95
    diglyme 385.37
    acrylic acid 130.65
    isopropyl myristate 130.08
    n-butyric acid 194.01
    acetyl acetate 147.99
    di(2-ethylhexyl) phthalate 118.71
    ethyl propionate 152.0
    nitromethane 231.06
    1,2-diethoxyethane 224.28
    benzonitrile 142.84
    trioctyl phosphate 105.15
    1-bromopropane 206.84
    gamma-valerolactone 441.41
    n-decanol 135.47
    triethyl phosphate 111.06
    4-methyl-2-pentanol 156.23
    propionitrile 125.58
    vinylene carbonate 186.91
    1,1,2-trichlorotrifluoroethane 290.98
    DMS 144.27
    cumene 95.29
    2-octanol 158.42
    2-hexanone 178.81
    octyl acetate 154.6
    limonene 144.13
    1,2-dimethoxyethane 386.09
    ethyl orthosilicate 117.4
    tributyl phosphate 102.63
    diacetone alcohol 275.61
    N,N-dimethylaniline 187.04
    acrylonitrile 136.99
    aniline 183.27
    1,3-propanediol 213.97
    bromobenzene 181.23
    dibromomethane 276.05
    1,1,2,2-tetrachloroethane 324.14
    2-methyl-cyclohexyl acetate 144.94
    tetrabutyl urea 147.86
    diisobutyl methanol 130.35
    2-phenylethanol 168.68
    styrene 125.88
    dioctyl adipate 156.45
    dimethyl sulfate 258.08
    ethyl butyrate 151.07
    methyl lactate 160.69
    butyl lactate 150.13
    diethyl carbonate 110.5
    propanediol butyl ether 217.23
    triethyl orthoformate 141.74
    p-tert-butyltoluene 119.45
    methyl 4-tert-butylbenzoate 235.79
    morpholine 427.88
    tert-butylamine 233.28
    n-dodecanol 117.01
    dimethoxymethane 532.53
    ethylene carbonate 167.3
    cyrene 219.68
    2-ethoxyethyl acetate 203.87
    2-ethylhexyl acetate 145.1
    1,2,4-trichlorobenzene 194.69
    4-methylpyridine 255.54
    dibutyl ether 163.34
    2,6-dimethyl-4-heptanol 130.35
    DEF 276.84
    dimethyl isosorbide 338.63
    tetrachloroethylene 241.94
    eugenol 217.02
    triacetin 183.16
    span 80 220.56
    1,4-butanediol 109.81
    1,1-dichloroethane 241.53
    2-methyl-1-pentanol 143.51
    methyl formate 182.63
    2-methyl-1-butanol 170.16
    n-decane 73.56
    butyronitrile 151.87
    3,7-dimethyl-1-octanol 143.56
    1-chlorooctane 131.2
    1-chlorotetradecane 82.66
    n-nonane 74.39
    undecane 60.89
    tert-butylcyclohexane 77.69
    cyclooctane 82.29
    cyclopentanol 289.43
    tetrahydropyran 379.23
    tert-amyl methyl ether 237.37
    2,5,8-trioxanonane 313.19
    1-hexene 149.42
    2-isopropoxyethanol 210.36
    2,2,2-trifluoroethanol 113.11
    methyl butyrate 170.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction