Phenyl Salicylate

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  • Identifiers

    CAS number
    118-55-8

    Molecular formula
    C13H10O3

    SMILES
    C1=CC=C(C=C1)OC(=O)C2=CC=CC=C2O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 72.17%
    Balsamic 68.33%
    Floral 67.98%
    Phenolic 55.82%
    Fruity 53.71%
    Herbal 51.34%
    Green 43.66%
    Woody 43.12%
    Aromatic 37.02%
    Honey 36.93%

     

    Flavor
    Bitter 44.68%
    Balsam 42.76%
    Phenolic 40.89%
    Sweet 36.99%
    Herbal 35.98%
    Wintergreen 30.17%
    Honey 29.19%
    Balsamic 28.05%
    Mild 26.72%
    Faint 26.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.8

    pKa est.
    9.1 (weak base)

    Molecular weight
    214.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 41-43
    • 43 °C

    Boiling point

    • 172-173
    • 172.00 to 173.00 °C. @ 12.00 mm Hg

    Flash point

    • 153.19 ˚C est.

    Solubility expt.

    • insoluble
    • 0.15 mg/mL at 25 °C
    • insoluble in water; soluble in 50% Heptane
    • moderately soluble (in ethanol)

  • Synonyms

    • Phenyl salicylate
    • 118-55-8
    • PHENYL 2-HYDROXYBENZOATE
    • Salol
    • Phenol salicylate
    • Salphenyl
    • Musol
    • 2-Phenoxycarbonylphenol
    • Benzoic acid, 2-hydroxy-, phenyl ester
    • Salicylic acid, phenyl ester
    • 2-Hydroxybenzoic acid phenyl ester
    • Phenyl-2-hydroxybenzoate
    • Fenylester kyseliny salicylove
    • Seesorb 201
    • 2-Hydroxy-benzoic acid phenyl ester
    • Seesorb K 201
    • NSC 33406
    • CCRIS 4859
    • Phenyl salicylate [NF]
    • 2-Hydroxybenzoic acid, phenyl ester
    • Salicylic Acid Phenyl Ester
    • EINECS 204-259-2
    • MFCD00002213
    • NSC-33406
    • Fenylester kyseliny salicylove [Czech]
    • BRN 0393969
    • DTXSID6021957
    • FEMA NO. 3960
    • CHEBI:34918
    • AI3-00195
    • 28A37T47QO
    • SALOL [VANDF]
    • SALOL [HPUS]
    • SALOL [MART.]
    • Phenyl salicylate melting point standard
    • PHENYL SALICYLATE [MI]
    • DTXCID201957
    • PHENYL SALICYLATE [FHFI]
    • PHENYL SALICYLATE [VANDF]
    • PHENYL SALICYLATE [USP-RS]
    • PHENYL SALICYLATE [WHO-DD]
    • NCGC00090887-02
    • SALOL (MART.)
    • PHENYL SALICYLATE (USP-RS)
    • CAS-118-55-8
    • phenylsalicylate
    • UNII-28A37T47QO
    • phenyl-salicylate
    • phenyl salicylic acid
    • 2Phenoxycarbonylphenol
    • salicylic phenyl ester
    • Phenyl 2hydroxybenzoate
    • WLN: QR BVOR
    • Oprea1_020651
    • Oprea1_771794
    • SCHEMBL24326
    • BIDD:ER0018
    • CHEMBL1339216
    • PHENYL SALICYLATE [INCI]
    • Phenyl salicylate, >=99%, FG
    • 2Hydroxybenzoic acid, phenyl ester
    • HY-B1731
    • NSC33406
    • STR06361
    • Tox21_113459
    • Tox21_201811
    • Tox21_302949
    • Phenyl Salicylate, Crystal, Purified
    • STK052177
    • Benzoic acid, 2hydroxy, phenyl ester
    • AKOS000121203
    • Tox21_113459_1
    • DB11071
    • FP34589
    • PS-7960
    • NCGC00090887-01
    • NCGC00090887-03
    • NCGC00090887-04
    • NCGC00090887-05
    • NCGC00091499-03
    • NCGC00256612-01
    • NCGC00259360-01
    • AC-11469
    • Phenyl salicylate, ReagentPlus(R), 99%
    • DB-024372
    • CS-0013740
    • NS00010218
    • S0017
    • EN300-18348
    • SBI-0653857.0001
    • AB00443435-03
    • Phenyl salicylate, Vetec(TM) reagent grade, 98%
    • Q421259
    • SR-01000883691
    • SR-01000883691-1
    • BRD-K44091963-001-01-5
    • Phenyl salicylate - Melting point 41.82 masculineC
    • Z57206005
    • Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate
    • 204-259-2
    • Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate, traceable to primary standards
    • Phenyl salicylate melting point standard, approximately 41 degrees, United States Pharmacopeia (USP) Reference Standard
    • Phenyl salicylate melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

  • Applications

    Phenyl Salicylate (CAS 118-55-8) is primarily used as a fragrance ingredient and fixative in perfumery, helping to impart a lasting floral aroma in cosmetics, personal care products, and household cleaners. It is commonly evaluated as a solvent or carrier for other fragrance components in formulation, and can act as an intermediate in the synthesis of additional fragrance materials. It may also be employed as a fragrance additive in coatings, inks, and related consumer products to impart odor. Applications include scented products such as air fresheners and cleaning products; usage is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 551.52
    methanol 489.61
    isopropanol 409.17
    water 0.05
    ethyl acetate 541.22
    n-propanol 536.67
    acetone 931.61
    n-butanol 476.96
    acetonitrile 489.53
    DMF 1290.16
    toluene 106.11
    isobutanol 359.32
    1,4-dioxane 807.3
    methyl acetate 585.12
    THF 1538.42
    2-butanone 979.83
    n-pentanol 151.77
    sec-butanol 549.46
    n-hexane 1.4
    ethylene glycol 48.83
    NMP 603.59
    cyclohexane 5.2
    DMSO 1609.76
    n-butyl acetate 219.09
    n-octanol 49.23
    chloroform 218.06
    n-propyl acetate 206.77
    acetic acid 266.39
    dichloromethane 190.54
    cyclohexanone 667.83
    propylene glycol 131.62
    isopropyl acetate 235.0
    DMAc 1017.44
    2-ethoxyethanol 242.72
    isopentanol 262.76
    n-heptane 1.74
    ethyl formate 252.8
    1,2-dichloroethane 341.1
    n-hexanol 122.21
    2-methoxyethanol 974.69
    isobutyl acetate 102.14
    tetrachloromethane 7.37
    n-pentyl acetate 81.36
    transcutol 1158.35
    n-heptanol 47.0
    ethylbenzene 43.52
    MIBK 210.19
    2-propoxyethanol 289.53
    tert-butanol 318.3
    MTBE 228.88
    2-butoxyethanol 129.83
    propionic acid 266.65
    o-xylene 44.64
    formic acid 65.74
    diethyl ether 359.57
    m-xylene 41.67
    p-xylene 50.55
    chlorobenzene 120.12
    dimethyl carbonate 187.58
    n-octane 0.95
    formamide 334.43
    cyclopentanone 917.65
    2-pentanone 584.39
    anisole 174.58
    cyclopentyl methyl ether 336.85
    gamma-butyrolactone 867.0
    1-methoxy-2-propanol 668.65
    pyridine 648.83
    3-pentanone 328.75
    furfural 491.46
    n-dodecane 2.86
    diethylene glycol 204.02
    diisopropyl ether 45.13
    tert-amyl alcohol 300.75
    acetylacetone 522.7
    n-hexadecane 3.44
    acetophenone 161.77
    methyl propionate 482.26
    isopentyl acetate 167.94
    trichloroethylene 559.28
    n-nonanol 48.53
    cyclohexanol 298.07
    benzyl alcohol 136.3
    2-ethylhexanol 63.35
    isooctanol 39.61
    dipropyl ether 80.93
    1,2-dichlorobenzene 86.46
    ethyl lactate 102.1
    propylene carbonate 342.65
    n-methylformamide 569.13
    2-pentanol 221.13
    n-pentane 1.51
    1-propoxy-2-propanol 187.93
    1-methoxy-2-propyl acetate 217.78
    2-(2-methoxypropoxy) propanol 177.69
    mesitylene 24.99
    ε-caprolactone 484.3
    p-cymene 24.37
    epichlorohydrin 1010.78
    1,1,1-trichloroethane 136.43
    2-aminoethanol 172.13
    morpholine-4-carbaldehyde 535.17
    sulfolane 838.69
    2,2,4-trimethylpentane 3.62
    2-methyltetrahydrofuran 777.99
    n-hexyl acetate 128.8
    isooctane 3.05
    2-(2-butoxyethoxy)ethanol 267.98
    sec-butyl acetate 133.67
    tert-butyl acetate 205.1
    decalin 5.63
    glycerin 170.2
    diglyme 509.27
    acrylic acid 190.36
    isopropyl myristate 54.53
    n-butyric acid 401.02
    acetyl acetate 213.41
    di(2-ethylhexyl) phthalate 43.97
    ethyl propionate 203.92
    nitromethane 874.89
    1,2-diethoxyethane 219.46
    benzonitrile 184.91
    trioctyl phosphate 33.95
    1-bromopropane 117.21
    gamma-valerolactone 837.09
    n-decanol 37.16
    triethyl phosphate 64.79
    4-methyl-2-pentanol 79.1
    propionitrile 368.25
    vinylene carbonate 271.81
    1,1,2-trichlorotrifluoroethane 383.59
    DMS 162.44
    cumene 25.4
    2-octanol 32.56
    2-hexanone 223.24
    octyl acetate 65.08
    limonene 37.61
    1,2-dimethoxyethane 544.01
    ethyl orthosilicate 53.82
    tributyl phosphate 47.77
    diacetone alcohol 313.22
    N,N-dimethylaniline 76.08
    acrylonitrile 474.48
    aniline 208.18
    1,3-propanediol 364.77
    bromobenzene 99.44
    dibromomethane 109.92
    1,1,2,2-tetrachloroethane 477.67
    2-methyl-cyclohexyl acetate 87.76
    tetrabutyl urea 65.18
    diisobutyl methanol 39.34
    2-phenylethanol 108.55
    styrene 67.44
    dioctyl adipate 85.85
    dimethyl sulfate 265.57
    ethyl butyrate 146.69
    methyl lactate 214.09
    butyl lactate 92.37
    diethyl carbonate 103.67
    propanediol butyl ether 147.94
    triethyl orthoformate 91.13
    p-tert-butyltoluene 24.67
    methyl 4-tert-butylbenzoate 105.85
    morpholine 1300.83
    tert-butylamine 112.58
    n-dodecanol 28.8
    dimethoxymethane 694.67
    ethylene carbonate 226.61
    cyrene 133.14
    2-ethoxyethyl acetate 146.3
    2-ethylhexyl acetate 116.19
    1,2,4-trichlorobenzene 125.48
    4-methylpyridine 492.31
    dibutyl ether 85.56
    2,6-dimethyl-4-heptanol 39.34
    DEF 546.07
    dimethyl isosorbide 249.99
    tetrachloroethylene 171.08
    eugenol 111.36
    triacetin 140.81
    span 80 116.52
    1,4-butanediol 57.24
    1,1-dichloroethane 213.47
    2-methyl-1-pentanol 128.77
    methyl formate 330.9
    2-methyl-1-butanol 301.11
    n-decane 3.67
    butyronitrile 364.56
    3,7-dimethyl-1-octanol 58.11
    1-chlorooctane 25.25
    1-chlorotetradecane 12.32
    n-nonane 2.49
    undecane 3.19
    tert-butylcyclohexane 5.43
    cyclooctane 1.36
    cyclopentanol 324.23
    tetrahydropyran 873.65
    tert-amyl methyl ether 175.88
    2,5,8-trioxanonane 342.26
    1-hexene 21.36
    2-isopropoxyethanol 138.54
    2,2,2-trifluoroethanol 65.77
    methyl butyrate 297.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction