Phenol, 2,4-dimethyl-6-(1-methylethyl)-(9CI)

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  • Identifiers

    CAS number
    143784-33-2

    Molecular formula
    C11H16O

    SMILES
    CC1=CC(=C(C(=C1)C(C)C)O)C

  • Odor profile

    Fragrance
    Phenolic 77.79%
    Spicy 68.96%
    Smoky 60.82%
    Medicinal 55.09%
    Leathery 53.42%
    Woody 50.33%
    Burnt 45.15%
    Herbal 42.49%
    Camphoreous 31.35%
    Musty 30.74%

     

    Flavor
    Phenolic 53.32%
    Medicinal 43.07%
    Woody 42.88%
    Camphor 38.39%
    Spice 37.48%
    Spicy 36.35%
    Herbal 32.06%
    Smoky 30.44%
    Musty 28.47%
    Smoke 26.24%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    10.71 (weak base)

    Molecular weight
    164.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    238°C

    Flash point

    • 109.46 ˚C est.

  • Synonyms

    • 143784-33-2
    • 2,4-dimethyl-6-propan-2-ylphenol
    • Phenol, 2,4-dimethyl-6-(1-methylethyl)- (9CI)
    • NoName_123
    • SCHEMBL4402447
    • DTXSID00901068
    • phenol, 2-isopropyl-4,6-dimethyl-
    • DB-288429
    • Phenol, 2,4-dimethyl-6-(1-methylethyl)-

  • Applications

    Phenol, 2,4-dimethyl-6-(1-methylethyl)-(9CI) (CAS 143784-33-2) is used as an odorant and fragrance ingredient in perfumery and cosmetics, where its substituted phenol structure contributes distinctive aroma notes and it can function as a fragrance fixative to extend scent duration. In plastics, rubbers and coatings, the compound can act as an antioxidant/stabilizer to inhibit oxidative degradation and extend service life. It can also serve as an intermediate in the synthesis of other phenolic compounds used in specialty chemicals, including fragrance-related intermediates. Additionally, it may be evaluated for use in cleaning products as a fragrance additive that enhances odor quality.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2431.04
    methanol 2057.97
    isopropanol 2428.5
    water 1.31
    ethyl acetate 2844.18
    n-propanol 2281.07
    acetone 4700.71
    n-butanol 2049.3
    acetonitrile 3828.19
    DMF 3985.2
    toluene 1315.43
    isobutanol 1783.57
    1,4-dioxane 6305.1
    methyl acetate 2685.82
    THF 9473.31
    2-butanone 3370.47
    n-pentanol 1403.86
    sec-butanol 1891.0
    n-hexane 1006.32
    ethylene glycol 247.85
    NMP 2022.62
    cyclohexane 771.26
    DMSO 2644.67
    n-butyl acetate 2553.75
    n-octanol 1150.63
    chloroform 4658.6
    n-propyl acetate 1726.59
    acetic acid 856.06
    dichloromethane 4684.66
    cyclohexanone 3751.88
    propylene glycol 392.74
    isopropyl acetate 1674.23
    DMAc 1505.45
    2-ethoxyethanol 1466.36
    isopentanol 1573.96
    n-heptane 457.08
    ethyl formate 1758.32
    1,2-dichloroethane 3725.41
    n-hexanol 2359.1
    2-methoxyethanol 2306.43
    isobutyl acetate 1162.39
    tetrachloromethane 950.31
    n-pentyl acetate 1245.19
    transcutol 2049.34
    n-heptanol 1032.23
    ethylbenzene 840.22
    MIBK 1664.63
    2-propoxyethanol 2532.17
    tert-butanol 2649.11
    MTBE 3715.67
    2-butoxyethanol 1205.28
    propionic acid 1093.98
    o-xylene 689.31
    formic acid 195.48
    diethyl ether 4586.83
    m-xylene 961.25
    p-xylene 945.2
    chlorobenzene 1427.14
    dimethyl carbonate 762.94
    n-octane 287.79
    formamide 423.04
    cyclopentanone 5084.54
    2-pentanone 3033.22
    anisole 1353.06
    cyclopentyl methyl ether 3551.68
    gamma-butyrolactone 4546.81
    1-methoxy-2-propanol 1933.55
    pyridine 2633.31
    3-pentanone 2013.89
    furfural 1964.01
    n-dodecane 186.73
    diethylene glycol 1075.48
    diisopropyl ether 1257.29
    tert-amyl alcohol 1845.88
    acetylacetone 2027.01
    n-hexadecane 218.88
    acetophenone 885.85
    methyl propionate 2033.73
    isopentyl acetate 1960.1
    trichloroethylene 4644.01
    n-nonanol 916.02
    cyclohexanol 1662.22
    benzyl alcohol 724.23
    2-ethylhexanol 1124.62
    isooctanol 834.9
    dipropyl ether 1885.27
    1,2-dichlorobenzene 1038.34
    ethyl lactate 508.9
    propylene carbonate 1888.37
    n-methylformamide 1949.1
    2-pentanol 1647.3
    n-pentane 725.39
    1-propoxy-2-propanol 1604.47
    1-methoxy-2-propyl acetate 1447.33
    2-(2-methoxypropoxy) propanol 579.89
    mesitylene 623.85
    ε-caprolactone 2576.29
    p-cymene 452.89
    epichlorohydrin 5396.74
    1,1,1-trichloroethane 3107.73
    2-aminoethanol 557.4
    morpholine-4-carbaldehyde 2418.6
    sulfolane 3333.41
    2,2,4-trimethylpentane 266.24
    2-methyltetrahydrofuran 5682.45
    n-hexyl acetate 1807.18
    isooctane 284.53
    2-(2-butoxyethoxy)ethanol 1028.98
    sec-butyl acetate 1045.91
    tert-butyl acetate 1722.03
    decalin 346.57
    glycerin 388.84
    diglyme 1967.54
    acrylic acid 682.37
    isopropyl myristate 635.19
    n-butyric acid 1632.89
    acetyl acetate 997.84
    di(2-ethylhexyl) phthalate 335.99
    ethyl propionate 1340.76
    nitromethane 2608.3
    1,2-diethoxyethane 2031.98
    benzonitrile 1206.32
    trioctyl phosphate 382.04
    1-bromopropane 2771.85
    gamma-valerolactone 4431.44
    n-decanol 674.94
    triethyl phosphate 394.91
    4-methyl-2-pentanol 891.54
    propionitrile 2955.04
    vinylene carbonate 1400.1
    1,1,2-trichlorotrifluoroethane 1277.02
    DMS 887.82
    cumene 556.92
    2-octanol 874.01
    2-hexanone 2001.98
    octyl acetate 844.67
    limonene 708.24
    1,2-dimethoxyethane 3456.23
    ethyl orthosilicate 420.18
    tributyl phosphate 410.76
    diacetone alcohol 1322.63
    N,N-dimethylaniline 782.03
    acrylonitrile 2658.19
    aniline 1011.03
    1,3-propanediol 1074.46
    bromobenzene 1576.23
    dibromomethane 3324.15
    1,1,2,2-tetrachloroethane 3356.85
    2-methyl-cyclohexyl acetate 770.44
    tetrabutyl urea 500.26
    diisobutyl methanol 620.42
    2-phenylethanol 991.9
    styrene 950.4
    dioctyl adipate 571.79
    dimethyl sulfate 932.58
    ethyl butyrate 1238.85
    methyl lactate 574.44
    butyl lactate 642.9
    diethyl carbonate 652.62
    propanediol butyl ether 910.68
    triethyl orthoformate 706.57
    p-tert-butyltoluene 495.25
    methyl 4-tert-butylbenzoate 722.35
    morpholine 5570.74
    tert-butylamine 1754.25
    n-dodecanol 514.7
    dimethoxymethane 3161.23
    ethylene carbonate 1455.86
    cyrene 565.59
    2-ethoxyethyl acetate 1208.16
    2-ethylhexyl acetate 1468.38
    1,2,4-trichlorobenzene 990.82
    4-methylpyridine 2582.39
    dibutyl ether 1459.06
    2,6-dimethyl-4-heptanol 620.42
    DEF 2326.43
    dimethyl isosorbide 1173.3
    tetrachloroethylene 2085.53
    eugenol 655.92
    triacetin 678.94
    span 80 605.02
    1,4-butanediol 493.37
    1,1-dichloroethane 3954.76
    2-methyl-1-pentanol 1104.47
    methyl formate 1736.04
    2-methyl-1-butanol 1450.56
    n-decane 335.21
    butyronitrile 3141.07
    3,7-dimethyl-1-octanol 806.96
    1-chlorooctane 1067.68
    1-chlorotetradecane 379.09
    n-nonane 376.44
    undecane 240.05
    tert-butylcyclohexane 378.77
    cyclooctane 356.17
    cyclopentanol 2061.87
    tetrahydropyran 6389.31
    tert-amyl methyl ether 1936.48
    2,5,8-trioxanonane 972.18
    1-hexene 2148.9
    2-isopropoxyethanol 1134.0
    2,2,2-trifluoroethanol 303.9
    methyl butyrate 1789.29

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction