Phenetole

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  • Identifiers

    CAS number
    103-73-1

    Molecular formula
    C8H10O

    SMILES
    CCOC1=CC=CC=C1

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Sweet 78.95%
    Anisic 56.4%
    Phenolic 50.45%
    Nutty 43.5%
    Ethereal 38.73%
    Aromatic 36.83%
    Pungent 30.79%
    Musty 30.08%
    Floral 29.07%
    Earthy 28.66%

     

    Flavor
    Sweet 47.83%
    Rose 44.62%
    Phenolic 43.02%
    Anise 41.82%
    Fruity 40.3%
    Floral 38.94%
    Green 37.19%
    Ethereal 35.74%
    Alcohol 32.12%
    Bitter 29.5%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    6.65 (neutral)

    Molecular weight
    122.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • -30.0 °C

    Boiling point

    • 171-173 °C

    Flash point

    • 48.05 ˚C est.
    • 145 °F (63 °C)OC

    Solubility expt.

    • SOL IN ETHANOL, ETHER, CARBON TETRACHLORIDE
    • Water Solubility = 5.69X10+2 mg/L at 25 °C

  • Synonyms

    • PHENETOLE
    • Ethoxybenzene
    • 103-73-1
    • Benzene, ethoxy-
    • Ethyl phenyl ether
    • Phenyl ethyl ether
    • Benzene, ethoxy
    • Phenoxyethane
    • MFCD00009090
    • Ether, ethyl phenyl-
    • RB8LU2C57F
    • CHEBI:67129
    • NSC-406706
    • Phenylcthylether
    • A Phenoxyethane
    • Ether, ethyl phenyl
    • Ethoxybenzene; Ethyl phenyl ether; NSC 406706; Phenetol; Phenoxyethane; Phenyl ethyl ether
    • HSDB 112
    • EINECS 203-139-7
    • UNII-RB8LU2C57F
    • NSC 406706
    • ethoxy-benzene
    • Methyl anisole
    • AI3-05616
    • 1-Ethoxybenzene
    • Ethoxybenzene, 99%
    • PHENETOLE [MI]
    • PHENETOLE [HSDB]
    • EC 203-139-7
    • WLN: 2OR
    • SCHEMBL18492
    • CHEMBL499585
    • DTXSID7059278
    • NSC406706
    • STL282470
    • AKOS000120160
    • FP16118
    • PB47848
    • LS-13425
    • CS-0017190
    • E0043
    • NS00002877
    • EN300-16115
    • D78866
    • A800791
    • Q419340
    • F1908-0060
    • InChI=1/C8H10O/c1-2-9-8-6-4-3-5-7-8/h3-7H,2H2,1H

  • Applications

    Phenetole (CAS 103-73-1) is an ethyl phenyl ether primarily used as a nonpolar organic solvent for coatings, varnishes, and inks in industrial settings; it also serves as a chemical intermediate in organic synthesis to prepare phenyl ether derivatives; in the fragrance and cosmetics sectors, phenetole is used as a fragrance ingredient or odor carrier to dissolve and stabilize aroma components; it can be employed as a solvent in cleaning formulations and detergents; in plastics and coating applications, it acts as a processing solvent for resin systems or finishes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1669.95
    methanol 1370.38
    isopropanol 1258.62
    water 2.06
    ethyl acetate 1938.12
    n-propanol 1292.47
    acetone 1904.48
    n-butanol 1160.8
    acetonitrile 2403.66
    DMF 1554.79
    toluene 1049.25
    isobutanol 996.59
    1,4-dioxane 3075.62
    methyl acetate 1754.81
    THF 2513.6
    2-butanone 1588.36
    n-pentanol 884.14
    sec-butanol 1151.99
    n-hexane 901.74
    ethylene glycol 383.29
    NMP 1363.96
    cyclohexane 1340.16
    DMSO 2773.28
    n-butyl acetate 1891.4
    n-octanol 853.84
    chloroform 6438.68
    n-propyl acetate 1301.49
    acetic acid 1487.4
    dichloromethane 7757.7
    cyclohexanone 2032.96
    propylene glycol 406.84
    isopropyl acetate 778.26
    DMAc 1189.34
    2-ethoxyethanol 983.4
    isopentanol 856.48
    n-heptane 1063.74
    ethyl formate 1173.52
    1,2-dichloroethane 3970.53
    n-hexanol 1425.63
    2-methoxyethanol 1277.99
    isobutyl acetate 647.11
    tetrachloromethane 1485.21
    n-pentyl acetate 811.27
    transcutol 2772.85
    n-heptanol 602.03
    ethylbenzene 673.02
    MIBK 664.61
    2-propoxyethanol 1427.81
    tert-butanol 1361.37
    MTBE 1265.62
    2-butoxyethanol 720.23
    propionic acid 1246.79
    o-xylene 631.1
    formic acid 273.64
    diethyl ether 2128.35
    m-xylene 583.69
    p-xylene 831.32
    chlorobenzene 1584.6
    dimethyl carbonate 568.61
    n-octane 329.73
    formamide 510.72
    cyclopentanone 1825.36
    2-pentanone 1263.6
    anisole 1101.84
    cyclopentyl methyl ether 1415.78
    gamma-butyrolactone 1974.99
    1-methoxy-2-propanol 930.45
    pyridine 2163.05
    3-pentanone 1216.37
    furfural 1535.62
    n-dodecane 242.04
    diethylene glycol 844.47
    diisopropyl ether 567.5
    tert-amyl alcohol 1087.71
    acetylacetone 1159.44
    n-hexadecane 264.35
    acetophenone 924.3
    methyl propionate 1370.17
    isopentyl acetate 1114.42
    trichloroethylene 5238.78
    n-nonanol 671.43
    cyclohexanol 1286.33
    benzyl alcohol 706.08
    2-ethylhexanol 960.06
    isooctanol 442.08
    dipropyl ether 1973.15
    1,2-dichlorobenzene 1417.31
    ethyl lactate 459.12
    propylene carbonate 1253.85
    n-methylformamide 924.64
    2-pentanol 849.73
    n-pentane 690.06
    1-propoxy-2-propanol 1123.16
    1-methoxy-2-propyl acetate 915.46
    2-(2-methoxypropoxy) propanol 798.34
    mesitylene 404.88
    ε-caprolactone 1650.65
    p-cymene 525.81
    epichlorohydrin 2620.15
    1,1,1-trichloroethane 3377.16
    2-aminoethanol 628.8
    morpholine-4-carbaldehyde 1430.99
    sulfolane 2349.73
    2,2,4-trimethylpentane 223.32
    2-methyltetrahydrofuran 2219.97
    n-hexyl acetate 1302.97
    isooctane 179.5
    2-(2-butoxyethoxy)ethanol 1036.64
    sec-butyl acetate 621.68
    tert-butyl acetate 727.78
    decalin 398.21
    glycerin 453.22
    diglyme 2059.21
    acrylic acid 930.32
    isopropyl myristate 578.65
    n-butyric acid 1347.26
    acetyl acetate 962.71
    di(2-ethylhexyl) phthalate 422.29
    ethyl propionate 1093.14
    nitromethane 2061.4
    1,2-diethoxyethane 1727.19
    benzonitrile 1279.98
    trioctyl phosphate 344.81
    1-bromopropane 2781.36
    gamma-valerolactone 1646.34
    n-decanol 516.85
    triethyl phosphate 517.12
    4-methyl-2-pentanol 389.57
    propionitrile 1821.47
    vinylene carbonate 1241.23
    1,1,2-trichlorotrifluoroethane 1402.94
    DMS 866.82
    cumene 440.13
    2-octanol 478.11
    2-hexanone 1197.71
    octyl acetate 706.85
    limonene 878.65
    1,2-dimethoxyethane 2050.92
    ethyl orthosilicate 484.23
    tributyl phosphate 472.23
    diacetone alcohol 648.05
    N,N-dimethylaniline 734.36
    acrylonitrile 1747.34
    aniline 985.47
    1,3-propanediol 743.66
    bromobenzene 1997.45
    dibromomethane 5767.16
    1,1,2,2-tetrachloroethane 3939.81
    2-methyl-cyclohexyl acetate 758.86
    tetrabutyl urea 606.45
    diisobutyl methanol 473.64
    2-phenylethanol 753.78
    styrene 976.5
    dioctyl adipate 785.96
    dimethyl sulfate 772.99
    ethyl butyrate 1426.56
    methyl lactate 459.19
    butyl lactate 527.28
    diethyl carbonate 939.61
    propanediol butyl ether 637.09
    triethyl orthoformate 779.17
    p-tert-butyltoluene 466.76
    methyl 4-tert-butylbenzoate 721.17
    morpholine 2512.57
    tert-butylamine 1136.21
    n-dodecanol 433.73
    dimethoxymethane 1275.42
    ethylene carbonate 1115.73
    cyrene 545.93
    2-ethoxyethyl acetate 877.0
    2-ethylhexyl acetate 936.66
    1,2,4-trichlorobenzene 1500.77
    4-methylpyridine 1803.2
    dibutyl ether 1457.41
    2,6-dimethyl-4-heptanol 473.64
    DEF 1399.7
    dimethyl isosorbide 1136.02
    tetrachloroethylene 2783.15
    eugenol 673.34
    triacetin 1019.2
    span 80 742.94
    1,4-butanediol 413.04
    1,1-dichloroethane 3728.53
    2-methyl-1-pentanol 708.79
    methyl formate 804.06
    2-methyl-1-butanol 895.05
    n-decane 384.52
    butyronitrile 1741.57
    3,7-dimethyl-1-octanol 679.41
    1-chlorooctane 1001.37
    1-chlorotetradecane 413.8
    n-nonane 450.11
    undecane 290.04
    tert-butylcyclohexane 333.55
    cyclooctane 428.67
    cyclopentanol 1273.97
    tetrahydropyran 2757.45
    tert-amyl methyl ether 884.62
    2,5,8-trioxanonane 1422.52
    1-hexene 1546.56
    2-isopropoxyethanol 690.46
    2,2,2-trifluoroethanol 389.24
    methyl butyrate 1433.43

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction