Perfluoroisohexane

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  • Identifiers

    CAS number
    355-04-4

    Molecular formula
    C6F14

    SMILES
    C(C(C(C(F)(F)F)(F)F)(F)F)(C(F)(F)F)(C(F)(F)F)F

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 51.18%
    Woody 26.05%
    Sweet 23.08%
    Fishy 22.3%
    Cooling 21.51%
    Balsamic 19.59%
    Dry 16.43%
    Clean 15.74%
    Savory 15.73%
    Animal 15.63%

     

    Flavor
    Odorless 30.03%
    Bitter 23.39%
    Bland 22.67%
    Sweet-like 17.41%
    Mild 16.77%
    Bloody 16.77%
    Sulfurous 16.72%
    Glue 16.6%
    Bouillon 16.58%
    Oriental 16.49%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    5.28 (weak acid)

    Molecular weight
    338.04 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    55°C

    Flash point

    • -6.74 ˚C est.

  • Synonyms

    • Perfluoroisohexane
    • 1,1,1,2,2,3,3,4,5,5,5-Undecafluoro-4-(trifluoromethyl)pentane
    • Perfluoro(2-methylpentane)
    • Tetradecafluoro-2-methylpentane
    • EINECS 206-575-6
    • 2-Perfluoromethylpentane
    • UNII-698P33664Y
    • FLUTEC PC-1
    • 698P33664Y
    • DTXSID40188992
    • EC 206-575-6
    • UNDECAFLUORO-2-(TRIFLUOROMETHYL)PENTANE
    • RefChem:171664
    • PERFLUOROISOHEXANE [INCI]
    • DTXCID00111483
    • ROVMKEZVKFJNBD-UHFFFAOYSA-N
    • 355-04-4
    • Perfluoro-2-methylpentane
    • MFCD00059905
    • Pentane, 1,1,1,2,2,3,3,4,5,5,5-undecafluoro-4-(trifluoromethyl)-
    • Pentane, undecafluoro-2-(trifluoromethyl)-
    • perfluoro-2-methyl-pentane
    • SCHEMBL396407
    • Tetradecafluoro-2-methyl pentane
    • AKOS007930289
    • FT60444
    • AS-86880
    • SY062383
    • NS00005350
    • T1012
    • D92438
    • F003292
    • Q22677415
    • 1,1,1,2,2,3,3,4,5,5,5-Undecafluoro-4-(trifluoromethyl)pentane #
    • 355-04-4

  • Applications

    Perfluoroisohexane (CAS 355-04-4) is used as a specialty solvent and processing aid in environments requiring chemical inertness and very low surface energy. In electronics and precision manufacturing, it is commonly employed as a cleaning/degreasing solvent for components and as a dielectric or heat-transfer fluid in cooling systems. In coatings and inks, it serves as a low-polarity solvent or diluent for fluorinated formulations. In laboratory and analytical workflows, it may be used as an inert solvent or purge medium for sample preparation and instrumentation. These applications are pursued under appropriate safety and regulatory considerations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 386.57
    methanol 1001.49
    isopropanol 217.89
    water 146.32
    ethyl acetate 362.05
    n-propanol 290.37
    acetone 560.87
    n-butanol 172.39
    acetonitrile 412.42
    DMF 1700.56
    toluene 159.1
    isobutanol 182.74
    1,4-dioxane 363.27
    methyl acetate 322.02
    THF 761.46
    2-butanone 387.4
    n-pentanol 145.11
    sec-butanol 199.36
    n-hexane 41.97
    ethylene glycol 303.84
    NMP 1368.02
    cyclohexane 65.67
    DMSO 2368.74
    n-butyl acetate 183.33
    n-octanol 97.48
    chloroform 190.12
    n-propyl acetate 239.99
    acetic acid 289.09
    dichloromethane 313.57
    cyclohexanone 329.21
    propylene glycol 215.71
    isopropyl acetate 231.35
    DMAc 1414.8
    2-ethoxyethanol 458.19
    isopentanol 124.8
    n-heptane 55.67
    ethyl formate 283.83
    1,2-dichloroethane 282.04
    n-hexanol 131.63
    2-methoxyethanol 683.94
    isobutyl acetate 106.52
    tetrachloromethane 46.7
    n-pentyl acetate 121.79
    transcutol 456.49
    n-heptanol 86.64
    ethylbenzene 94.49
    MIBK 213.17
    2-propoxyethanol 426.7
    tert-butanol 212.42
    MTBE 207.45
    2-butoxyethanol 197.56
    propionic acid 266.97
    o-xylene 149.81
    formic acid 435.25
    diethyl ether 381.75
    m-xylene 132.99
    p-xylene 86.51
    chlorobenzene 76.09
    dimethyl carbonate 377.87
    n-octane 25.97
    formamide 757.65
    cyclopentanone 493.64
    2-pentanone 345.7
    anisole 211.97
    cyclopentyl methyl ether 407.37
    gamma-butyrolactone 681.1
    1-methoxy-2-propanol 555.74
    pyridine 337.89
    3-pentanone 384.4
    furfural 490.88
    n-dodecane 18.92
    diethylene glycol 420.66
    diisopropyl ether 133.54
    tert-amyl alcohol 190.07
    acetylacetone 390.4
    n-hexadecane 20.33
    acetophenone 244.09
    methyl propionate 445.48
    isopentyl acetate 113.28
    trichloroethylene 269.53
    n-nonanol 98.81
    cyclohexanol 155.54
    benzyl alcohol 173.21
    2-ethylhexanol 86.41
    isooctanol 63.31
    dipropyl ether 251.76
    1,2-dichlorobenzene 69.69
    ethyl lactate 234.97
    propylene carbonate 301.92
    n-methylformamide 922.84
    2-pentanol 145.93
    n-pentane 71.23
    1-propoxy-2-propanol 293.84
    1-methoxy-2-propyl acetate 299.64
    2-(2-methoxypropoxy) propanol 232.4
    mesitylene 100.24
    ε-caprolactone 315.75
    p-cymene 81.33
    epichlorohydrin 474.92
    1,1,1-trichloroethane 102.48
    2-aminoethanol 342.62
    morpholine-4-carbaldehyde 857.78
    sulfolane 909.39
    2,2,4-trimethylpentane 26.99
    2-methyltetrahydrofuran 367.45
    n-hexyl acetate 142.49
    isooctane 19.43
    2-(2-butoxyethoxy)ethanol 246.64
    sec-butyl acetate 152.68
    tert-butyl acetate 212.48
    decalin 24.57
    glycerin 334.37
    diglyme 443.93
    acrylic acid 279.38
    isopropyl myristate 86.98
    n-butyric acid 212.39
    acetyl acetate 195.23
    di(2-ethylhexyl) phthalate 65.3
    ethyl propionate 311.05
    nitromethane 812.5
    1,2-diethoxyethane 240.26
    benzonitrile 129.61
    trioctyl phosphate 62.83
    1-bromopropane 187.21
    gamma-valerolactone 635.85
    n-decanol 79.37
    triethyl phosphate 137.34
    4-methyl-2-pentanol 91.12
    propionitrile 296.83
    vinylene carbonate 284.09
    1,1,2-trichlorotrifluoroethane 338.58
    DMS 191.91
    cumene 66.02
    2-octanol 64.49
    2-hexanone 208.86
    octyl acetate 102.09
    limonene 110.67
    1,2-dimethoxyethane 638.94
    ethyl orthosilicate 121.32
    tributyl phosphate 71.69
    diacetone alcohol 252.01
    N,N-dimethylaniline 241.92
    acrylonitrile 385.88
    aniline 179.9
    1,3-propanediol 253.52
    bromobenzene 65.83
    dibromomethane 219.18
    1,1,2,2-tetrachloroethane 222.79
    2-methyl-cyclohexyl acetate 123.8
    tetrabutyl urea 145.98
    diisobutyl methanol 65.77
    2-phenylethanol 147.42
    styrene 102.29
    dioctyl adipate 118.65
    dimethyl sulfate 579.82
    ethyl butyrate 223.71
    methyl lactate 397.29
    butyl lactate 130.14
    diethyl carbonate 159.26
    propanediol butyl ether 168.73
    triethyl orthoformate 171.97
    p-tert-butyltoluene 81.86
    methyl 4-tert-butylbenzoate 199.92
    morpholine 490.73
    tert-butylamine 163.3
    n-dodecanol 62.08
    dimethoxymethane 1021.36
    ethylene carbonate 255.25
    cyrene 308.93
    2-ethoxyethyl acetate 175.91
    2-ethylhexyl acetate 100.37
    1,2,4-trichlorobenzene 81.83
    4-methylpyridine 290.93
    dibutyl ether 118.24
    2,6-dimethyl-4-heptanol 65.77
    DEF 581.25
    dimethyl isosorbide 394.76
    tetrachloroethylene 174.45
    eugenol 190.64
    triacetin 197.64
    span 80 151.45
    1,4-butanediol 156.86
    1,1-dichloroethane 159.57
    2-methyl-1-pentanol 101.16
    methyl formate 622.59
    2-methyl-1-butanol 142.22
    n-decane 31.35
    butyronitrile 197.89
    3,7-dimethyl-1-octanol 75.18
    1-chlorooctane 60.2
    1-chlorotetradecane 32.56
    n-nonane 30.3
    undecane 23.92
    tert-butylcyclohexane 20.81
    cyclooctane 39.49
    cyclopentanol 208.24
    tetrahydropyran 288.04
    tert-amyl methyl ether 232.29
    2,5,8-trioxanonane 362.5
    1-hexene 86.61
    2-isopropoxyethanol 273.28
    2,2,2-trifluoroethanol 213.93
    methyl butyrate 312.73

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction