Perfluorodecalin

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  • Identifiers

    CAS number
    306-94-5

    Molecular formula
    C10F18

    SMILES
    C12(C(C(C(C(C1(F)F)(F)F)(F)F)(F)F)(C(C(C(C2(F)F)(F)F)(F)F)(F)F)F)F

    Safety labels

  • Odor profile

    Fragrance
    Odorless 64.58%
    Fishy 21.13%
    Woody 20.61%
    Sweet 18.07%
    Cooling 17.37%
    Animal 13.26%
    Savory 13.19%
    Balsamic 12.76%
    Burnt 12.75%
    Clean 12.62%

     

    Flavor
    Bitter 37.1%
    Odorless 31.91%
    Sweet-like 19.83%
    Bland 18.94%
    Bouillon 18.38%
    Rotten 18.15%
    Nitrile 18.09%
    Bloody 18.06%
    Scallion 17.79%
    Glue 17.7%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.6

    pKa est.
    4.36 (weak acid)

    Molecular weight
    462.08 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    141°C

    Flash point

    • 28.66 ˚C est.

  • Synonyms

    • Perfluorodecalin
    • 306-94-5
    • Perflunafene
    • Octadecafluorodecahydronaphthalene
    • Perflunafeno
    • Perflunafenum
    • Acri-deca
    • DTXSID0046511
    • Fluosol da perfluorodecalin
    • NSC-97066
    • 54A06VV62N
    • DTXCID8026511
    • CHEBI:38848
    • PERFTORAN COMPONENT PERFLUORODECALIN
    • decalin perfluoride
    • fluosol-DC
    • RefChem:860191
    • Octadecafluorodecahydronaphtalene
    • Naphthalene,1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecahydro-
    • 206-192-4
    • cis-Perfluorodecalin
    • trans-Perfluorodecalin
    • 60433-11-6
    • 60433-12-7
    • Perfluorodecahydronaphthalene
    • Naphthalene, octadecafluorodecahydro-
    • F-DC
    • PP 5
    • MFCD00010626
    • Naphthalene, 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecahydro-
    • Cis-perfluorodecaline
    • MFCD00153231
    • MFCD00153232
    • NSC 97066
    • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluoronaphthalene
    • C10F18
    • cis-Perfluorodecahydronaphthalene
    • Perflunafene (INN)
    • NCGC00165971-01
    • PERFLUNAFENE [INN]
    • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-Octadecafluorodecahydronaphthalene
    • octadecafluorodecalin
    • Perflunafenum [Latin]
    • Perflunafeno [Spanish]
    • Perflunafene [INN:BAN]
    • CAS-306-94-5
    • perfluoro(decahydronaphthalene)
    • EINECS 206-192-4
    • BRN 2067113
    • UNII-54A06VV62N
    • decahydrooctadecafluoronaphthalene
    • Octadecafluorodecalin; PP 5; PP 6; Perflunafene; Perfluorodecahydronaphthalene
    • Acri-deca (TN)
    • Perfluorodecaline-cis
    • Octadecafluorodecaline
    • Perfluorodecalin (cis)
    • Perfluorodecalin, 95%
    • Perfluorodecaline, cis-
    • Perfluorodecalin (trans)
    • NAPHTHALENE, DECAHYDROOCTADECAFLUORO-
    • SCHEMBL63605
    • SCHEMBL63606
    • PERFLUNAFENE [MART.]
    • 3-05-00-00249 (Beilstein Handbook Reference)
    • PERFLUNAFENE [WHO-DD]
    • orb2813900
    • SCHEMBL1069193
    • PERFLUORODECALIN [VANDF]
    • CHEMBL1371129
    • UWEYRJFJVCLAGH-IJWZVTFUSA-N
    • UWEYRJFJVCLAGH-XIXRPRMCSA-N
    • DTXSID201015480
    • DTXSID801021518
    • octadecafluoro-decahydro-naphthalene
    • NSC97066
    • Tox21_112274
    • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecalin
    • EBC-48134
    • MSK180918
    • AKOS005258619
    • AKOS016015609
    • AKOS016015610
    • Tox21_112274_1
    • FP29570
    • FP93879
    • FS-4493
    • FLUOSOL DA PERFLUORODECALIN [MI]
    • NCGC00165971-02
    • MS-20338
    • MS-20597
    • SY012675
    • DB-016682
    • DB-230121
    • DB-234092
    • HY-108298
    • Naphthalene, octadecafluorodecahydro-, cis-
    • (4ar,8ar)-Octadecafluorodecahydronaphthalene
    • CS-0028172
    • NS00013970
    • P0837
    • D08338
    • D92022
    • A832725
    • F003283
    • F007015
    • F007016
    • Q413677
    • SR-01000883733
    • SR-01000883733-1
    • BRD-K55401595-001-01-8
    • Z1741957451
    • Octadecafluorodecahydronaphthalene, (cis+trans), >=94% (GC)
    • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-Octadecafluorodecahydronaphthalene, cis-
    • 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecakis(fluoranyl)naphthalene
    • Naphthalene,1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecahydro-,trans-
    • Octadecafluorodecali; PP 5; PP 6; Perflunafene; Perfluorodecahydronahthalene
    • 306-94-5

  • Applications

    Perfluorodecalin is a chemically inert, high-density fluorinated liquid with very high gas solubility, enabling several niche applications across industries. In biomedical contexts, it has been used as an oxygen carrier in perfluorochemical emulsions and as an oxygenation medium for cell culture and tissue preservation research, supporting oxygen delivery in experimental systems. It is also evaluated as a dielectric coolant or heat-transfer fluid for electronics and photonics because of its chemical stability and favorable thermal properties. In precision cleaning, it serves as a solvent for sensitive components and optical coatings, offering effective cleaning performance without aggressive residues. In the coatings and inks sector, it acts as a processing medium for fluorinated formulations and as a component in specialty solvents for fluoropolymer coatings, enabling controlled deposition and phase behavior. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.38
    methanol 53.96
    isopropanol 11.69
    water 4.17
    ethyl acetate 99.72
    n-propanol 15.64
    acetone 100.22
    n-butanol 10.2
    acetonitrile 63.1
    DMF 270.37
    toluene 24.79
    isobutanol 9.56
    1,4-dioxane 128.2
    methyl acetate 101.87
    THF 157.19
    2-butanone 83.81
    n-pentanol 9.27
    sec-butanol 12.22
    n-hexane 2.78
    ethylene glycol 20.13
    NMP 344.51
    cyclohexane 8.35
    DMSO 418.57
    n-butyl acetate 73.48
    n-octanol 13.42
    chloroform 27.34
    n-propyl acetate 56.82
    acetic acid 46.82
    dichloromethane 45.19
    cyclohexanone 105.85
    propylene glycol 11.5
    isopropyl acetate 63.61
    DMAc 301.77
    2-ethoxyethanol 56.19
    isopentanol 7.98
    n-heptane 7.12
    ethyl formate 60.79
    1,2-dichloroethane 39.67
    n-hexanol 14.05
    2-methoxyethanol 83.48
    isobutyl acetate 22.34
    tetrachloromethane 8.29
    n-pentyl acetate 39.23
    transcutol 79.98
    n-heptanol 11.32
    ethylbenzene 12.82
    MIBK 33.93
    2-propoxyethanol 74.39
    tert-butanol 12.57
    MTBE 27.37
    2-butoxyethanol 33.96
    propionic acid 40.04
    o-xylene 24.35
    formic acid 54.23
    diethyl ether 50.47
    m-xylene 16.78
    p-xylene 15.7
    chlorobenzene 16.28
    dimethyl carbonate 96.16
    n-octane 4.03
    formamide 112.57
    cyclopentanone 140.55
    2-pentanone 62.7
    anisole 31.27
    cyclopentyl methyl ether 71.56
    gamma-butyrolactone 198.51
    1-methoxy-2-propanol 54.21
    pyridine 80.57
    3-pentanone 82.48
    furfural 140.52
    n-dodecane 3.23
    diethylene glycol 63.73
    diisopropyl ether 19.77
    tert-amyl alcohol 13.91
    acetylacetone 126.17
    n-hexadecane 3.76
    acetophenone 52.56
    methyl propionate 108.76
    isopentyl acetate 42.69
    trichloroethylene 53.46
    n-nonanol 13.92
    cyclohexanol 17.94
    benzyl alcohol 20.45
    2-ethylhexanol 13.46
    isooctanol 8.72
    dipropyl ether 47.24
    1,2-dichlorobenzene 15.93
    ethyl lactate 40.19
    propylene carbonate 91.27
    n-methylformamide 132.25
    2-pentanol 9.23
    n-pentane 3.44
    1-propoxy-2-propanol 53.17
    1-methoxy-2-propyl acetate 112.54
    2-(2-methoxypropoxy) propanol 42.13
    mesitylene 12.68
    ε-caprolactone 109.59
    p-cymene 17.64
    epichlorohydrin 109.57
    1,1,1-trichloroethane 20.95
    2-aminoethanol 18.67
    morpholine-4-carbaldehyde 277.97
    sulfolane 279.32
    2,2,4-trimethylpentane 2.17
    2-methyltetrahydrofuran 81.28
    n-hexyl acetate 39.93
    isooctane 1.28
    2-(2-butoxyethoxy)ethanol 42.18
    sec-butyl acetate 38.54
    tert-butyl acetate 55.13
    decalin 3.44
    glycerin 28.03
    diglyme 105.71
    acrylic acid 44.38
    isopropyl myristate 22.4
    n-butyric acid 31.95
    acetyl acetate 88.41
    di(2-ethylhexyl) phthalate 15.88
    ethyl propionate 69.82
    nitromethane 208.02
    1,2-diethoxyethane 66.24
    benzonitrile 27.65
    trioctyl phosphate 14.88
    1-bromopropane 18.27
    gamma-valerolactone 218.92
    n-decanol 11.22
    triethyl phosphate 46.94
    4-methyl-2-pentanol 6.5
    propionitrile 34.5
    vinylene carbonate 84.13
    1,1,2-trichlorotrifluoroethane 84.01
    DMS 80.54
    cumene 8.54
    2-octanol 9.73
    2-hexanone 43.59
    octyl acetate 27.97
    limonene 27.07
    1,2-dimethoxyethane 114.95
    ethyl orthosilicate 36.35
    tributyl phosphate 19.6
    diacetone alcohol 44.39
    N,N-dimethylaniline 29.73
    acrylonitrile 58.81
    aniline 23.04
    1,3-propanediol 20.94
    bromobenzene 15.73
    dibromomethane 26.15
    1,1,2,2-tetrachloroethane 39.41
    2-methyl-cyclohexyl acetate 43.23
    tetrabutyl urea 34.2
    diisobutyl methanol 10.59
    2-phenylethanol 24.3
    styrene 13.08
    dioctyl adipate 32.82
    dimethyl sulfate 177.42
    ethyl butyrate 74.45
    methyl lactate 69.09
    butyl lactate 27.07
    diethyl carbonate 53.21
    propanediol butyl ether 22.05
    triethyl orthoformate 53.0
    p-tert-butyltoluene 16.39
    methyl 4-tert-butylbenzoate 41.86
    morpholine 111.68
    tert-butylamine 7.6
    n-dodecanol 9.19
    dimethoxymethane 155.32
    ethylene carbonate 77.87
    cyrene 68.37
    2-ethoxyethyl acetate 68.89
    2-ethylhexyl acetate 44.25
    1,2,4-trichlorobenzene 22.61
    4-methylpyridine 61.82
    dibutyl ether 24.97
    2,6-dimethyl-4-heptanol 10.59
    DEF 137.76
    dimethyl isosorbide 106.83
    tetrachloroethylene 33.13
    eugenol 31.73
    triacetin 65.43
    span 80 27.68
    1,4-butanediol 11.81
    1,1-dichloroethane 21.19
    2-methyl-1-pentanol 7.83
    methyl formate 118.9
    2-methyl-1-butanol 8.97
    n-decane 5.29
    butyronitrile 22.53
    3,7-dimethyl-1-octanol 11.55
    1-chlorooctane 11.6
    1-chlorotetradecane 6.3
    n-nonane 4.87
    undecane 4.06
    tert-butylcyclohexane 2.35
    cyclooctane 4.69
    cyclopentanol 24.46
    tetrahydropyran 66.1
    tert-amyl methyl ether 31.78
    2,5,8-trioxanonane 79.15
    1-hexene 6.63
    2-isopropoxyethanol 35.46
    2,2,2-trifluoroethanol 45.76
    methyl butyrate 70.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction