(+-)-Palmitoyl carnitine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1935-18-8

    Molecular formula
    C23H45NO4

    SMILES
    CCCCCCCCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 55.65%
    Fatty 52.86%
    Oily 37.34%
    Odorless 36.79%
    Milky 26.41%
    Creamy 25.71%
    Woody 21.46%
    Animal 20.86%
    Dairy 20.63%
    Lactonic 20.19%

     

    Flavor
    Bland 39.76%
    Mild 33.93%
    Odorless 29.23%
    Oily 23.16%
    Faint 22.89%
    Slightly waxy 21.6%
    Bay oil 20.84%
    Delicate 20.43%
    Beer 20.2%
    Fatty 19.84%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.7

    pKa est.
    5.22 (weak acid)

    Molecular weight
    399.6 g/mol

    Flash point

    • -27.36 ˚C est.

  • Synonyms

    • PALMITOYLCARNITINE
    • 1935-18-8
    • Palmitylcarnitine
    • 3-hexadecanoyloxy-4-(trimethylazaniumyl)butanoate
    • U8K6DKA8V2
    • DTXSID90895028
    • 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, inner salt
    • RefChem:905514
    • (+-)-Palmitoyl carnitine
    • DTXCID101324587
    • O-palmitoylcarnitine
    • O-hexadecanoylcarnitine
    • PALMITOYL-CARNITINE
    • 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-, inner salt
    • 3-(hexadecanoyloxy)-4-(trimethylazaniumyl)butanoate
    • (+/-)-palmitoyl carnitine
    • CHEBI:73067
    • 3-(hexadecanoyloxy)-4-(trimethylammonio)butanoate
    • palmitoyl-dl-carnitine
    • C23H45NO4
    • UNII-U8K6DKA8V2
    • MFCD00152152
    • carnitine palmitate
    • hexadecanoylcarnitines
    • Acylcarnitine C16:0
    • DL-PALMITOYLCARNITINE
    • PALMITYL-DL-CARNITINE
    • PALMITOYL DL-CARNITINE
    • SCHEMBL115183
    • CHEMBL301722
    • orb1992734
    • O-HEXADECANOYL-DL-CARNITINE
    • BDBM50230701
    • LMFA07070098
    • AKOS027326556
    • EBC-616081
    • PALMITOYL CARNITINE, (+/-)-
    • AC(16:0)
    • FP172246
    • HY-126357
    • CS-0102941
    • 3-hexadecanoyloxy-4-(trimethylammonio)butanoate
    • H61236
    • ( inverted exclamation mark_)-Palmitoyl carnitine
    • Q7128408
    • (+-)-3-Carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-1-propanaminium inner salt
    • 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, inner salt, (+-)-
    • AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, HYDROXIDE, INNER SALT, PALMITATE
    • PALMITIC ACID, ESTER WITH (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYLAMMONIUM HYDROXIDE INNER SALT
    • 1935-18-8

  • Applications

    (+-)-Palmitoyl carnitine (CAS 1935-18-8) is primarily used in research and chemical synthesis as a lipid-like acylcarnitine; typical applications include serving as a substrate or analytical standard in fatty acid oxidation and carnitine palmitoyltransferase (CPT1)–related enzyme assays, and as a building block for the synthesis of acylcarnitine derivatives; it also functions as an analytical reference compound in LC–MS workflows for acylcarnitines; in formulation work it may act as a lipophilic excipient or conditioning agent in cosmetic/personal care products; and in pharmaceutical R&D it is explored as a lipophilic carrier system or a prodrug-related moiety, subject to regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 106.8
    methanol 275.67
    isopropanol 41.68
    water 16.82
    ethyl acetate 102.37
    n-propanol 86.55
    acetone 107.25
    n-butanol 51.56
    acetonitrile 51.57
    DMF 365.4
    toluene 51.92
    isobutanol 60.17
    1,4-dioxane 97.22
    methyl acetate 107.75
    THF 264.12
    2-butanone 102.24
    n-pentanol 44.55
    sec-butanol 50.85
    n-hexane 4.29
    ethylene glycol 57.9
    NMP 1304.87
    cyclohexane 12.89
    DMSO 354.63
    n-butyl acetate 88.8
    n-octanol 31.8
    chloroform 399.25
    n-propyl acetate 110.03
    acetic acid 590.03
    dichloromethane 423.38
    cyclohexanone 340.99
    propylene glycol 84.91
    isopropyl acetate 73.96
    DMAc 594.32
    2-ethoxyethanol 140.41
    isopentanol 41.27
    n-heptane 3.74
    ethyl formate 100.95
    1,2-dichloroethane 220.88
    n-hexanol 35.05
    2-methoxyethanol 219.53
    isobutyl acetate 76.6
    tetrachloromethane 73.11
    n-pentyl acetate 129.65
    transcutol 513.08
    n-heptanol 41.12
    ethylbenzene 31.52
    MIBK 58.44
    2-propoxyethanol 133.96
    tert-butanol 49.31
    MTBE 30.86
    2-butoxyethanol 160.83
    propionic acid 274.95
    o-xylene 56.19
    formic acid 431.1
    diethyl ether 25.95
    m-xylene 46.37
    p-xylene 48.89
    chlorobenzene 92.99
    dimethyl carbonate 104.17
    n-octane 2.19
    formamide 456.18
    cyclopentanone 429.67
    2-pentanone 78.22
    anisole 60.45
    cyclopentyl methyl ether 155.61
    gamma-butyrolactone 672.75
    1-methoxy-2-propanol 155.41
    pyridine 188.28
    3-pentanone 87.05
    furfural 497.41
    n-dodecane 1.34
    diethylene glycol 113.53
    diisopropyl ether 12.28
    tert-amyl alcohol 61.52
    acetylacetone 147.6
    n-hexadecane 1.52
    acetophenone 130.45
    methyl propionate 154.26
    isopentyl acetate 84.75
    trichloroethylene 559.35
    n-nonanol 31.37
    cyclohexanol 111.66
    benzyl alcohol 89.92
    2-ethylhexanol 30.84
    isooctanol 38.55
    dipropyl ether 31.14
    1,2-dichlorobenzene 121.06
    ethyl lactate 107.24
    propylene carbonate 351.85
    n-methylformamide 273.6
    2-pentanol 28.91
    n-pentane 3.33
    1-propoxy-2-propanol 105.85
    1-methoxy-2-propyl acetate 137.62
    2-(2-methoxypropoxy) propanol 142.81
    mesitylene 29.47
    ε-caprolactone 417.78
    p-cymene 25.08
    epichlorohydrin 435.53
    1,1,1-trichloroethane 190.32
    2-aminoethanol 132.45
    morpholine-4-carbaldehyde 552.77
    sulfolane 1189.09
    2,2,4-trimethylpentane 4.6
    2-methyltetrahydrofuran 162.32
    n-hexyl acetate 114.53
    isooctane 1.96
    2-(2-butoxyethoxy)ethanol 183.9
    sec-butyl acetate 72.6
    tert-butyl acetate 94.18
    decalin 8.65
    glycerin 173.67
    diglyme 331.18
    acrylic acid 309.31
    isopropyl myristate 29.38
    n-butyric acid 252.3
    acetyl acetate 94.63
    di(2-ethylhexyl) phthalate 64.62
    ethyl propionate 94.7
    nitromethane 540.46
    1,2-diethoxyethane 71.63
    benzonitrile 82.87
    trioctyl phosphate 42.28
    1-bromopropane 68.32
    gamma-valerolactone 650.95
    n-decanol 19.1
    triethyl phosphate 73.96
    4-methyl-2-pentanol 21.03
    propionitrile 49.34
    vinylene carbonate 328.74
    1,1,2-trichlorotrifluoroethane 672.66
    DMS 144.21
    cumene 26.81
    2-octanol 25.13
    2-hexanone 75.89
    octyl acetate 47.66
    limonene 38.4
    1,2-dimethoxyethane 133.29
    ethyl orthosilicate 67.58
    tributyl phosphate 55.74
    diacetone alcohol 145.26
    N,N-dimethylaniline 63.21
    acrylonitrile 87.36
    aniline 92.69
    1,3-propanediol 112.11
    bromobenzene 91.68
    dibromomethane 204.83
    1,1,2,2-tetrachloroethane 455.32
    2-methyl-cyclohexyl acetate 107.24
    tetrabutyl urea 74.57
    diisobutyl methanol 16.25
    2-phenylethanol 71.27
    styrene 32.77
    dioctyl adipate 78.24
    dimethyl sulfate 321.22
    ethyl butyrate 80.89
    methyl lactate 151.68
    butyl lactate 168.8
    diethyl carbonate 62.18
    propanediol butyl ether 155.96
    triethyl orthoformate 78.98
    p-tert-butyltoluene 23.62
    methyl 4-tert-butylbenzoate 171.06
    morpholine 199.14
    tert-butylamine 25.33
    n-dodecanol 12.37
    dimethoxymethane 142.04
    ethylene carbonate 243.23
    cyrene 231.22
    2-ethoxyethyl acetate 183.19
    2-ethylhexyl acetate 77.87
    1,2,4-trichlorobenzene 197.6
    4-methylpyridine 153.05
    dibutyl ether 26.59
    2,6-dimethyl-4-heptanol 16.25
    DEF 181.62
    dimethyl isosorbide 293.92
    tetrachloroethylene 350.51
    eugenol 154.28
    triacetin 264.31
    span 80 141.33
    1,4-butanediol 53.18
    1,1-dichloroethane 141.46
    2-methyl-1-pentanol 44.09
    methyl formate 182.7
    2-methyl-1-butanol 56.57
    n-decane 2.82
    butyronitrile 41.03
    3,7-dimethyl-1-octanol 29.01
    1-chlorooctane 18.46
    1-chlorotetradecane 5.56
    n-nonane 2.58
    undecane 1.85
    tert-butylcyclohexane 6.2
    cyclooctane 4.88
    cyclopentanol 143.64
    tetrahydropyran 105.94
    tert-amyl methyl ether 45.05
    2,5,8-trioxanonane 211.66
    1-hexene 14.69
    2-isopropoxyethanol 95.77
    2,2,2-trifluoroethanol 340.26
    methyl butyrate 133.94

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction