Palmitoyl Alanine

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  • Identifiers

    CAS number
    56255-31-3

    Molecular formula
    C19H37NO3

    SMILES
    CCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 38.47%
    Waxy 36.67%
    Fatty 36.49%
    Savory 35.5%
    Meaty 32.78%
    Oily 25.65%
    Milky 25.64%
    Citrus 25.58%
    Cooling 23.23%
    Herbal 21.84%

     

    Flavor
    Odorless 39.18%
    Bland 38.12%
    Mild 33.86%
    Fatty 27.25%
    Faint 26.59%
    Waxy 23.58%
    Slightly waxy 22.55%
    Bay oil 21.4%
    Cultured dairy 20.38%
    Delicate 20.01%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.9

    pKa est.
    7.29 (neutral)

    Molecular weight
    327.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    428°C

    Flash point

    • 215.73 ˚C est.

  • Synonyms

    • 56255-31-3
    • Palmitoyl alanine
    • Palmitoyl-L-alanine
    • N-Hexadecanoyl-L-alanine
    • N-Palmitoyl-L-alanine
    • Codeage PA
    • Palmityl-L-alanine
    • 68HNC9TLVC
    • L-Alanine, N-(1-oxohexadecyl)-
    • DTXSID80204807
    • RefChem:858420
    • PALMITOYL ALANINE [INCI]
    • DTXCID70127298
    • (S)-2-Palmitamidopropanoic acid
    • N-palmitoyl alanine
    • N-HEXADECANOYL-ALANINE
    • Alanine, N-(1-oxohexadecyl)-
    • (2S)-2-(hexadecanoylamino)propanoic acid
    • C19H37NO3
    • MFCD26793456
    • UNII-68HNC9TLVC
    • (S)-2-Palmitamidopropanoicacid
    • N-Palmitoyl L-alanine
    • N-hexadecanoyl-(l)-alanine
    • SCHEMBL542879
    • CHEMBL388991
    • orb1695764
    • CHEBI:165549
    • LMFA08020123
    • AKOS016014303
    • FD21038
    • AS-15978
    • SY456334
    • N-Hexadecanoyl-alanine (palmitoyl-Ala-OH)
    • HY-121907
    • F324071
    • Q27264253
    • 56255-31-3

  • Applications

    Palmitoyl Alanine (CAS 56255-31-3), an N-acyl amino acid derivative, is typically evaluated for cosmetic and personal care applications as an emollient and conditioning agent, and may function as a mild surfactant or emulsifier in cleansing and hair-care formulations; in industrial contexts it can be used as a monomer or modifier in polymers and coatings to introduce hydrophobic character; in coatings, inks, and adhesives it may serve as an additive to adjust film-forming properties and adhesion; and given its lipid-amino structure, it is also considered a lipidated building block for peptide-lipid conjugates and related biomaterial applications, subject to formulation constraints and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 25.74
    methanol 45.07
    isopropanol 24.82
    water 0.09
    ethyl acetate 36.91
    n-propanol 26.53
    acetone 42.05
    n-butanol 24.63
    acetonitrile 12.91
    DMF 148.43
    toluene 15.9
    isobutanol 23.23
    1,4-dioxane 56.62
    methyl acetate 37.03
    THF 190.96
    2-butanone 54.32
    n-pentanol 28.68
    sec-butanol 30.01
    n-hexane 3.5
    ethylene glycol 3.45
    NMP 286.33
    cyclohexane 7.25
    DMSO 226.62
    n-butyl acetate 62.0
    n-octanol 23.79
    chloroform 102.88
    n-propyl acetate 74.34
    acetic acid 40.97
    dichloromethane 106.37
    cyclohexanone 177.97
    propylene glycol 10.88
    isopropyl acetate 49.24
    DMAc 326.34
    2-ethoxyethanol 79.81
    isopentanol 34.52
    n-heptane 2.22
    ethyl formate 30.83
    1,2-dichloroethane 82.9
    n-hexanol 21.21
    2-methoxyethanol 75.08
    isobutyl acetate 52.19
    tetrachloromethane 22.79
    n-pentyl acetate 90.55
    transcutol 322.48
    n-heptanol 24.8
    ethylbenzene 17.12
    MIBK 57.58
    2-propoxyethanol 65.75
    tert-butanol 48.55
    MTBE 54.52
    2-butoxyethanol 83.7
    propionic acid 34.8
    o-xylene 21.67
    formic acid 16.82
    diethyl ether 22.79
    m-xylene 16.34
    p-xylene 26.54
    chlorobenzene 30.32
    dimethyl carbonate 18.37
    n-octane 1.94
    formamide 34.34
    cyclopentanone 188.05
    2-pentanone 50.12
    anisole 38.89
    cyclopentyl methyl ether 75.1
    gamma-butyrolactone 173.26
    1-methoxy-2-propanol 75.5
    pyridine 60.83
    3-pentanone 44.23
    furfural 135.79
    n-dodecane 1.28
    diethylene glycol 33.91
    diisopropyl ether 13.74
    tert-amyl alcohol 57.95
    acetylacetone 81.93
    n-hexadecane 1.49
    acetophenone 66.83
    methyl propionate 36.88
    isopentyl acetate 76.67
    trichloroethylene 142.98
    n-nonanol 24.16
    cyclohexanol 46.46
    benzyl alcohol 36.55
    2-ethylhexanol 20.25
    isooctanol 26.18
    dipropyl ether 24.83
    1,2-dichlorobenzene 42.42
    ethyl lactate 38.78
    propylene carbonate 100.49
    n-methylformamide 45.11
    2-pentanol 20.52
    n-pentane 1.9
    1-propoxy-2-propanol 61.38
    1-methoxy-2-propyl acetate 77.87
    2-(2-methoxypropoxy) propanol 76.78
    mesitylene 13.76
    ε-caprolactone 163.25
    p-cymene 13.64
    epichlorohydrin 158.97
    1,1,1-trichloroethane 74.57
    2-aminoethanol 14.42
    morpholine-4-carbaldehyde 176.8
    sulfolane 352.69
    2,2,4-trimethylpentane 4.16
    2-methyltetrahydrofuran 116.68
    n-hexyl acetate 85.14
    isooctane 2.03
    2-(2-butoxyethoxy)ethanol 107.77
    sec-butyl acetate 57.73
    tert-butyl acetate 83.87
    decalin 6.8
    glycerin 21.74
    diglyme 224.7
    acrylic acid 27.27
    isopropyl myristate 25.38
    n-butyric acid 67.74
    acetyl acetate 32.72
    di(2-ethylhexyl) phthalate 30.62
    ethyl propionate 50.23
    nitromethane 79.11
    1,2-diethoxyethane 83.04
    benzonitrile 35.57
    trioctyl phosphate 21.62
    1-bromopropane 36.89
    gamma-valerolactone 281.56
    n-decanol 15.13
    triethyl phosphate 38.09
    4-methyl-2-pentanol 19.79
    propionitrile 17.12
    vinylene carbonate 69.32
    1,1,2-trichlorotrifluoroethane 136.3
    DMS 49.77
    cumene 15.89
    2-octanol 21.11
    2-hexanone 69.38
    octyl acetate 33.85
    limonene 22.29
    1,2-dimethoxyethane 161.81
    ethyl orthosilicate 39.44
    tributyl phosphate 30.0
    diacetone alcohol 102.35
    N,N-dimethylaniline 37.88
    acrylonitrile 20.48
    aniline 24.11
    1,3-propanediol 27.98
    bromobenzene 32.07
    dibromomethane 66.23
    1,1,2,2-tetrachloroethane 159.77
    2-methyl-cyclohexyl acetate 62.92
    tetrabutyl urea 47.73
    diisobutyl methanol 16.23
    2-phenylethanol 31.5
    styrene 18.23
    dioctyl adipate 49.97
    dimethyl sulfate 57.79
    ethyl butyrate 54.5
    methyl lactate 31.8
    butyl lactate 73.94
    diethyl carbonate 31.71
    propanediol butyl ether 71.44
    triethyl orthoformate 51.31
    p-tert-butyltoluene 13.62
    methyl 4-tert-butylbenzoate 80.2
    morpholine 94.18
    tert-butylamine 27.34
    n-dodecanol 10.08
    dimethoxymethane 56.9
    ethylene carbonate 62.3
    cyrene 90.95
    2-ethoxyethyl acetate 106.49
    2-ethylhexyl acetate 59.1
    1,2,4-trichlorobenzene 56.79
    4-methylpyridine 63.0
    dibutyl ether 37.84
    2,6-dimethyl-4-heptanol 16.23
    DEF 100.39
    dimethyl isosorbide 155.62
    tetrachloroethylene 101.65
    eugenol 74.17
    triacetin 97.24
    span 80 65.71
    1,4-butanediol 15.2
    1,1-dichloroethane 56.68
    2-methyl-1-pentanol 38.8
    methyl formate 27.55
    2-methyl-1-butanol 32.29
    n-decane 2.85
    butyronitrile 23.39
    3,7-dimethyl-1-octanol 25.27
    1-chlorooctane 17.77
    1-chlorotetradecane 4.97
    n-nonane 2.57
    undecane 1.78
    tert-butylcyclohexane 5.56
    cyclooctane 2.26
    cyclopentanol 50.32
    tetrahydropyran 73.38
    tert-amyl methyl ether 52.42
    2,5,8-trioxanonane 131.71
    1-hexene 13.54
    2-isopropoxyethanol 64.97
    2,2,2-trifluoroethanol 23.8
    methyl butyrate 89.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction