Palmitamidopropyltrimonium chloride

Overview IFRA Request a quote

  • Identifiers

    CAS number
    51277-96-4

    Molecular formula
    C22H47ClN2O

    SMILES
    CCCCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)C.[Cl-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 43.48%
    Fatty 34.76%
    Meaty 32.57%
    Fishy 32.49%
    Savory 31.64%
    Woody 29.61%
    Animal 29.44%
    Oily 28.41%
    Cooling 26.61%
    Odorless 24.8%

     

    Flavor
    Bland 36.06%
    Mild 29.8%
    Faint 23.54%
    Odorless 23.04%
    Slightly waxy 21.79%
    Delicate 21.56%
    Herbal 21.03%
    Bay oil 20.17%
    Leathery 19.6%
    Diterpene 19.59%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.85 (neutral)

    Molecular weight
    391.1 g/mol

    Flash point

    • 101.06 ˚C est.

  • Synonyms

    • Palmitamidopropyltrimonium chloride
    • (Hexadecylamidopropyl)trimethylammonium chloride
    • VARISOFT PATC
    • N2U96D202F
    • UNII-N2U96D202F
    • TEGO CARE CE 40 PELLETS
    • DTXSID90885949
    • EINECS 257-104-6
    • 1-Propanaminium, N,N,N-trimethyl-3-((1-oxohexadecyl)amino)-, chloride
    • 1-Propanaminium, N,N,N-trimethyl-3-((1-oxohexadecyl)amino)-, chloride (1:1)
    • TRIMETHYL(3-PALMITAMIDOPROPYL)AMMONIUM CHLORIDE
    • 1-Propanaminium, N,N,N-trimethyl-3-[(1-oxohexadecyl)amino]-, chloride
    • 1-Propanaminium, N,N,N-trimethyl-3-[(1-oxohexadecyl)amino]-, chloride (1:1)
    • RefChem:169713
    • DTXCID001025304
    • PALMITAMIDOPROPYLTRIMONIUM CHLORIDE [INCI]
    • 51277-96-4
    • 3-(hexadecanoylamino)propyl-trimethylazanium;chloride
    • 3-(hexadecanoylamino)propyl-trimethylazanium chloride
    • SCHEMBL115006
    • DB-251982
    • NS00124070
    • Q27284436
    • 3-Hexadecanamido-N,N,N-trimethylpropan-1-aminium chloride
    • 51277-96-4

  • Applications

    Palmitamidopropyltrimonium chloride (CAS 51277-96-4) is a cationic surfactant used as a conditioning and emulsifying agent in various formulations. In cosmetics and personal care, it acts as a conditioning surfactant for hair and skin cleansers. In household products, it serves as a fabric-softening agent and mild surfactant in detergents. In industrial manufacturing, it can function as an emulsifier and dispersant in polymer and coating systems, aiding stability of emulsions. In coatings and inks, it is used as a cationic additive to improve wetting and leveling and to modify formulation properties. In plastics and polymers, it may be employed as a surface-active modifier to impart charge and compatibility. It is typically used within product-specific constraints and regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 120.37
    methanol 160.05
    isopropanol 115.3
    water 0.8
    ethyl acetate 360.06
    n-propanol 161.69
    acetone 253.9
    n-butanol 186.35
    acetonitrile 80.24
    DMF 422.55
    toluene 160.35
    isobutanol 178.95
    1,4-dioxane 321.71
    methyl acetate 256.01
    THF 656.22
    2-butanone 356.8
    n-pentanol 143.05
    sec-butanol 184.96
    n-hexane 47.15
    ethylene glycol 21.2
    NMP 904.29
    cyclohexane 180.54
    DMSO 406.63
    n-butyl acetate 358.15
    n-octanol 127.58
    chloroform 1204.18
    n-propyl acetate 390.23
    acetic acid 375.21
    dichloromethane 935.43
    cyclohexanone 941.92
    propylene glycol 51.81
    isopropyl acetate 340.79
    DMAc 834.07
    2-ethoxyethanol 270.32
    isopentanol 215.44
    n-heptane 45.96
    ethyl formate 212.49
    1,2-dichloroethane 598.04
    n-hexanol 135.0
    2-methoxyethanol 283.7
    isobutyl acetate 305.54
    tetrachloromethane 359.4
    n-pentyl acetate 492.72
    transcutol 956.8
    n-heptanol 143.75
    ethylbenzene 98.24
    MIBK 319.08
    2-propoxyethanol 252.88
    tert-butanol 198.51
    MTBE 297.12
    2-butoxyethanol 359.3
    propionic acid 285.12
    o-xylene 162.02
    formic acid 129.32
    diethyl ether 236.86
    m-xylene 127.75
    p-xylene 157.11
    chlorobenzene 250.07
    dimethyl carbonate 121.09
    n-octane 19.06
    formamide 153.19
    cyclopentanone 786.99
    2-pentanone 369.84
    anisole 165.19
    cyclopentyl methyl ether 540.7
    gamma-butyrolactone 774.01
    1-methoxy-2-propanol 281.73
    pyridine 337.86
    3-pentanone 363.34
    furfural 597.85
    n-dodecane 8.53
    diethylene glycol 124.59
    diisopropyl ether 122.95
    tert-amyl alcohol 284.06
    acetylacetone 393.2
    n-hexadecane 10.5
    acetophenone 264.56
    methyl propionate 309.78
    isopentyl acetate 370.55
    trichloroethylene 1141.1
    n-nonanol 125.84
    cyclohexanol 414.11
    benzyl alcohol 148.99
    2-ethylhexanol 142.0
    isooctanol 151.59
    dipropyl ether 221.24
    1,2-dichlorobenzene 299.88
    ethyl lactate 189.72
    propylene carbonate 526.1
    n-methylformamide 208.82
    2-pentanol 168.39
    n-pentane 40.8
    1-propoxy-2-propanol 280.15
    1-methoxy-2-propyl acetate 350.08
    2-(2-methoxypropoxy) propanol 253.27
    mesitylene 102.44
    ε-caprolactone 826.02
    p-cymene 94.47
    epichlorohydrin 737.83
    1,1,1-trichloroethane 768.99
    2-aminoethanol 72.31
    morpholine-4-carbaldehyde 607.01
    sulfolane 1177.98
    2,2,4-trimethylpentane 48.19
    2-methyltetrahydrofuran 596.53
    n-hexyl acetate 431.13
    isooctane 20.97
    2-(2-butoxyethoxy)ethanol 346.48
    sec-butyl acetate 323.94
    tert-butyl acetate 434.92
    decalin 53.46
    glycerin 92.38
    diglyme 819.91
    acrylic acid 214.55
    isopropyl myristate 118.49
    n-butyric acid 526.07
    acetyl acetate 267.75
    di(2-ethylhexyl) phthalate 120.94
    ethyl propionate 321.55
    nitromethane 456.45
    1,2-diethoxyethane 351.47
    benzonitrile 168.0
    trioctyl phosphate 95.57
    1-bromopropane 366.66
    gamma-valerolactone 980.36
    n-decanol 76.87
    triethyl phosphate 198.0
    4-methyl-2-pentanol 122.68
    propionitrile 114.48
    vinylene carbonate 414.79
    1,1,2-trichlorotrifluoroethane 889.12
    DMS 233.2
    cumene 80.6
    2-octanol 112.14
    2-hexanone 323.55
    octyl acetate 156.59
    limonene 186.08
    1,2-dimethoxyethane 456.2
    ethyl orthosilicate 211.93
    tributyl phosphate 128.9
    diacetone alcohol 377.54
    N,N-dimethylaniline 142.97
    acrylonitrile 122.66
    aniline 180.05
    1,3-propanediol 129.94
    bromobenzene 268.46
    dibromomethane 631.62
    1,1,2,2-tetrachloroethane 1213.74
    2-methyl-cyclohexyl acetate 300.76
    tetrabutyl urea 168.76
    diisobutyl methanol 97.38
    2-phenylethanol 137.88
    styrene 104.66
    dioctyl adipate 199.46
    dimethyl sulfate 316.85
    ethyl butyrate 336.83
    methyl lactate 172.12
    butyl lactate 346.46
    diethyl carbonate 194.77
    propanediol butyl ether 264.25
    triethyl orthoformate 314.54
    p-tert-butyltoluene 88.75
    methyl 4-tert-butylbenzoate 317.49
    morpholine 496.45
    tert-butylamine 143.73
    n-dodecanol 50.32
    dimethoxymethane 255.27
    ethylene carbonate 386.18
    cyrene 270.93
    2-ethoxyethyl acetate 498.01
    2-ethylhexyl acetate 348.09
    1,2,4-trichlorobenzene 383.99
    4-methylpyridine 348.9
    dibutyl ether 217.94
    2,6-dimethyl-4-heptanol 97.38
    DEF 550.97
    dimethyl isosorbide 434.05
    tetrachloroethylene 900.65
    eugenol 239.07
    triacetin 461.92
    span 80 246.45
    1,4-butanediol 61.54
    1,1-dichloroethane 526.63
    2-methyl-1-pentanol 174.76
    methyl formate 156.54
    2-methyl-1-butanol 233.36
    n-decane 22.55
    butyronitrile 152.78
    3,7-dimethyl-1-octanol 133.86
    1-chlorooctane 119.61
    1-chlorotetradecane 29.44
    n-nonane 23.08
    undecane 12.89
    tert-butylcyclohexane 43.39
    cyclooctane 49.63
    cyclopentanol 331.43
    tetrahydropyran 568.93
    tert-amyl methyl ether 342.6
    2,5,8-trioxanonane 402.77
    1-hexene 110.31
    2-isopropoxyethanol 231.58
    2,2,2-trifluoroethanol 227.47
    methyl butyrate 460.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction