Padimate-O

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  • Identifiers

    CAS number
    21245-02-3

    Molecular formula
    C17H27NO2

    SMILES
    CCCCC(CC)COC(=O)C1=CC=C(C=C1)N(C)C

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fruity 45.08%
    Sweet 42.09%
    Floral 38.34%
    Herbal 38.27%
    Grape 32.34%
    Mint 32.33%
    Balsamic 31.66%
    Fresh 27.88%
    Spicy 27.19%
    Citrus 26.44%

     

    Flavor
    Herbal 51.69%
    Green 33.34%
    Fruity 29.74%
    Floral 26.31%
    Woody 26.15%
    Oily 25.46%
    Warm 24.74%
    Mild 22.99%
    Waxy 22.6%
    Spicy 22.28%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.0

    pKa est.
    7.15 (neutral)

    Molecular weight
    277.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 362
    • 325 °C

    Flash point

    • 163.96 ˚C est.

    Solubility expt.

    • Insoluble
    • Soluble in alcohol, isopropyl alcohol, mineral oil; practically insoluble in water, glycerin, propylene glycol

  • Synonyms

    • Padimate-O
    • 2-ethylhexyl-p-dimethylaminobenzoate
    • RefChem:56662
    • 4-N,N'-dimethylamino-benzoic acid, 2-ethylhexyl ester
    • 2-Ethylhexyl 4-(dimethylamino)benzoate
    • 21245-02-3
    • Padimate O
    • 2-ETHYLHEXYL 4-DIMETHYLAMINOBENZOATE
    • Escalol 507
    • Octyl dimethyl PABA
    • Eusolex 6007
    • Arlatone UVB
    • Benzoic acid, 4-(dimethylamino)-, 2-ethylhexyl ester
    • 2-Ethylhexyl p-dimethylaminobenzoate
    • 4-(Dimethylamino)benzoic acid 2-ethylhexyl ester
    • MFCD00017526
    • Uvasorb dmo
    • 2-Ethylhexyl-4-dimethylaminobenzoate
    • 2-Ethylhexyl p-(dimethylamino)benzoate
    • ETHYLHEXYL DIMETHYL PABA
    • DTXSID7029320
    • 2-Ethylhexyl-p-dimethyl-aminobenzoate
    • Z11006CMUZ
    • NCGC00090764-02
    • DTXCID109320
    • Radiacare Lip Balm
    • CAS-21245-02-3
    • Octyl dimethyl p-aminobenzoate
    • Caraloe Snow & Sun Lip Balm
    • Pamimate o
    • HSDB 7169
    • EINECS 244-289-3
    • Padimate O (USP)
    • Arlatone UVB (TN)
    • Photoplex (Salt/Mix)
    • Padimate o [USAN:USP]
    • PreSun 23 (Salt/Mix)
    • PADIMATE O [HSDB]
    • PADIMATE O [USAN]
    • PADIMATE O [VANDF]
    • PADIMATE-O [VANDF]
    • PAMIMATE O [VANDF]
    • UNII-Z11006CMUZ
    • PADIMATE O [MART.]
    • SCHEMBL15432
    • PADIMATE O [USP-RS]
    • PADIMATE O [WHO-DD]
    • 4-(Dimethylamino)benzoic acid, 2-ethylhexyl ester
    • MLS001055379
    • (+/-)-PADIMATE O
    • Benzoic acid, p-(dimethylamino)-, 2-ethylhexyl ester
    • orb1705538
    • Padimate O, analytical standard
    • Radiacare Lip Balm (Salt/Mix)
    • CHEMBL1323699
    • MSK3403
    • CHEBI:135932
    • PADIMATE O, (+/-)-
    • HMS3039F10
    • PADIMATE O [USP MONOGRAPH]
    • OCTYL DIMETHYL PABA [VANDF]
    • Tox21_111013
    • Tox21_202421
    • Tox21_303574
    • EBC-26412
    • SBB008471
    • 2-ethylhexyl-4-dimethylamino benzoate
    • AKOS015890282
    • MSK3403-1000A
    • Tox21_111013_1
    • 2-Ethylhexyl-4'-dimethylamino-benzoate
    • DB11570
    • FE70802
    • NCGC00090764-01
    • NCGC00090764-03
    • NCGC00090764-04
    • NCGC00257250-01
    • NCGC00259970-01
    • 2-ethylhexyl n,n-dimethyl-p-aminobenzoate
    • AC-13165
    • AS-75461
    • SMR000677935
    • Caraloe Snow & Sun Lip Balm (Salt/Mix)
    • DB-021046
    • 2-ETHYL-HEXYL 4-DIMETHYLAMINOBENZOATE
    • D1871
    • NS00005726
    • ST50826077
    • 2-Ethylhexyl 4-(dimethylamino)benzoate, 98%
    • 2-ETHYLHEXYL 4-(DIMETYLAMINO)BENZOATE
    • p-Dimethylaminobenzoic acid 2-ethylhexyl ester
    • D05335
    • F71555
    • SBI-0654058.0001
    • EN300-22984143
    • F214776
    • SR-01000864568
    • Q6628390
    • SR-01000864568-2
    • 4-(DIMETHYLAMINO)BENZOIC ACID 2-ETHYLHEXYL ESTER [MI]
    • Ethylhexyl dimethyl PABA Solution in Acetonitrile, 1000ug/mL
    • Padimate O, United States Pharmacopeia (USP) Reference Standard
    • Padimate O, Pharmaceutical Secondary Standard; Certified Reference Material
    • 21245-02-3

  • Applications

    Padimate-O (CAS 21245-02-3) is the octyl ester of p-aminobenzoic acid, used primarily as a UV absorber in cosmetics and personal care, particularly in sunscreen formulations and makeup products; it may also function as a UV stabilizer for plastics and polymers to mitigate UV-induced degradation, and is considered as an additive for UV stabilization in coatings and inks as well as in adhesive formulations to enhance outdoor durability; use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1018.65
    methanol 1367.46
    isopropanol 568.71
    water 0.78
    ethyl acetate 2579.88
    n-propanol 935.43
    acetone 2510.92
    n-butanol 812.26
    acetonitrile 1471.62
    DMF 2729.08
    toluene 794.64
    isobutanol 678.97
    1,4-dioxane 1244.68
    methyl acetate 1703.39
    THF 1391.79
    2-butanone 1774.42
    n-pentanol 490.03
    sec-butanol 629.37
    n-hexane 37.65
    ethylene glycol 138.05
    NMP 2711.04
    cyclohexane 97.99
    DMSO 2891.88
    n-butyl acetate 1076.44
    n-octanol 107.98
    chloroform 6727.31
    n-propyl acetate 1023.83
    acetic acid 1763.1
    dichloromethane 7765.32
    cyclohexanone 2553.54
    propylene glycol 220.25
    isopropyl acetate 1187.3
    DMAc 2233.98
    2-ethoxyethanol 907.98
    isopentanol 723.43
    n-heptane 10.41
    ethyl formate 1120.41
    1,2-dichloroethane 5774.45
    n-hexanol 380.18
    2-methoxyethanol 1476.52
    isobutyl acetate 519.11
    tetrachloromethane 716.28
    n-pentyl acetate 553.27
    transcutol 3312.55
    n-heptanol 154.25
    ethylbenzene 283.67
    MIBK 815.55
    2-propoxyethanol 852.74
    tert-butanol 741.17
    MTBE 1059.38
    2-butoxyethanol 463.1
    propionic acid 1103.93
    o-xylene 476.08
    formic acid 632.03
    diethyl ether 1205.6
    m-xylene 477.97
    p-xylene 404.87
    chlorobenzene 1840.77
    dimethyl carbonate 686.81
    n-octane 5.03
    formamide 1473.05
    cyclopentanone 2486.89
    2-pentanone 1682.84
    anisole 682.81
    cyclopentyl methyl ether 1087.46
    gamma-butyrolactone 2832.47
    1-methoxy-2-propanol 1025.39
    pyridine 1924.84
    3-pentanone 1369.51
    furfural 2314.16
    n-dodecane 3.9
    diethylene glycol 576.54
    diisopropyl ether 274.56
    tert-amyl alcohol 744.99
    acetylacetone 1951.32
    n-hexadecane 4.95
    acetophenone 813.51
    methyl propionate 1680.37
    isopentyl acetate 894.85
    trichloroethylene 9599.31
    n-nonanol 104.12
    cyclohexanol 830.74
    benzyl alcohol 614.77
    2-ethylhexanol 221.12
    isooctanol 146.6
    dipropyl ether 246.59
    1,2-dichlorobenzene 1656.19
    ethyl lactate 372.68
    propylene carbonate 1571.67
    n-methylformamide 1775.01
    2-pentanol 519.79
    n-pentane 35.34
    1-propoxy-2-propanol 566.15
    1-methoxy-2-propyl acetate 1008.76
    2-(2-methoxypropoxy) propanol 407.79
    mesitylene 256.19
    ε-caprolactone 2134.08
    p-cymene 139.56
    epichlorohydrin 3922.96
    1,1,1-trichloroethane 3791.6
    2-aminoethanol 431.21
    morpholine-4-carbaldehyde 1878.05
    sulfolane 3535.48
    2,2,4-trimethylpentane 36.1
    2-methyltetrahydrofuran 1431.97
    n-hexyl acetate 592.51
    isooctane 21.13
    2-(2-butoxyethoxy)ethanol 634.54
    sec-butyl acetate 682.11
    tert-butyl acetate 1069.99
    decalin 48.62
    glycerin 346.87
    diglyme 1403.24
    acrylic acid 1056.88
    isopropyl myristate 151.1
    n-butyric acid 1820.51
    acetyl acetate 1438.68
    di(2-ethylhexyl) phthalate 184.78
    ethyl propionate 834.15
    nitromethane 4048.87
    1,2-diethoxyethane 907.52
    benzonitrile 934.2
    trioctyl phosphate 120.27
    1-bromopropane 1951.5
    gamma-valerolactone 2874.13
    n-decanol 69.0
    triethyl phosphate 267.19
    4-methyl-2-pentanol 270.99
    propionitrile 1055.24
    vinylene carbonate 1443.77
    1,1,2-trichlorotrifluoroethane 2719.08
    DMS 724.68
    cumene 172.95
    2-octanol 99.97
    2-hexanone 811.51
    octyl acetate 212.04
    limonene 220.28
    1,2-dimethoxyethane 1151.54
    ethyl orthosilicate 249.23
    tributyl phosphate 187.87
    diacetone alcohol 982.74
    N,N-dimethylaniline 406.74
    acrylonitrile 1442.11
    aniline 1142.87
    1,3-propanediol 670.23
    bromobenzene 2003.16
    dibromomethane 4346.19
    1,1,2,2-tetrachloroethane 6993.97
    2-methyl-cyclohexyl acetate 439.18
    tetrabutyl urea 222.03
    diisobutyl methanol 118.35
    2-phenylethanol 488.74
    styrene 435.86
    dioctyl adipate 269.9
    dimethyl sulfate 1164.19
    ethyl butyrate 634.04
    methyl lactate 560.6
    butyl lactate 416.47
    diethyl carbonate 422.73
    propanediol butyl ether 393.0
    triethyl orthoformate 363.28
    p-tert-butyltoluene 126.49
    methyl 4-tert-butylbenzoate 442.18
    morpholine 1787.42
    tert-butylamine 427.67
    n-dodecanol 47.74
    dimethoxymethane 1384.76
    ethylene carbonate 1215.06
    cyrene 471.47
    2-ethoxyethyl acetate 958.58
    2-ethylhexyl acetate 682.82
    1,2,4-trichlorobenzene 1934.78
    4-methylpyridine 2070.78
    dibutyl ether 187.03
    2,6-dimethyl-4-heptanol 118.35
    DEF 2170.53
    dimethyl isosorbide 791.45
    tetrachloroethylene 3931.92
    eugenol 431.68
    triacetin 598.06
    span 80 321.64
    1,4-butanediol 263.37
    1,1-dichloroethane 4465.83
    2-methyl-1-pentanol 518.19
    methyl formate 1168.96
    2-methyl-1-butanol 786.78
    n-decane 7.14
    butyronitrile 1006.74
    3,7-dimethyl-1-octanol 159.81
    1-chlorooctane 92.3
    1-chlorotetradecane 27.78
    n-nonane 6.22
    undecane 4.97
    tert-butylcyclohexane 37.24
    cyclooctane 21.72
    cyclopentanol 679.93
    tetrahydropyran 1482.01
    tert-amyl methyl ether 729.01
    2,5,8-trioxanonane 734.86
    1-hexene 255.08
    2-isopropoxyethanol 626.97
    2,2,2-trifluoroethanol 757.32
    methyl butyrate 1234.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction