p-Methylphenoxyacetaldehyde

Overview IFRA Request a quote

  • Identifiers

    CAS number
    67845-46-9

    Molecular formula
    C9H10O2

    SMILES
    CC1=CC=C(C=C1)OCC=O

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 80.42%
    Green 55.65%
    Fresh 45.8%
    Sweet 42.66%
    Hyacinth 35.69%
    Powdery 35.05%
    Lily 34.25%
    Ozone 33.8%
    Honey 33.55%
    Aldehydic 32.39%

     

    Flavor
    Sweet 81.07%
    Floral 59.07%
    Vanilla 54.4%
    Fruity 49.42%
    Cherry 49.04%
    Balsam 47.82%
    Spicy 47.25%
    Powdery 45.72%
    Almond 45.13%
    Bitter 41.55%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    6.47 (neutral)

    Molecular weight
    150.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    256°C

    Flash point

    • 103.18 ˚C est.

  • Synonyms

    • (4-Methylphenoxy)acetaldehyde
    • 67845-46-9
    • p-Methylphenoxyacetaldehyde
    • p-Cresoxyacetaldehyde
    • 2-(4-methylphenoxy)acetaldehyde
    • Acetaldehyde, (4-methylphenoxy)-
    • p-Methylphenyloxyacetaldehyde
    • Acetaldehyde, 2-(4-methylphenoxy)-
    • HQL6T929HS
    • EINECS 267-317-6
    • ACETALDEHYDE, PARA-METHYL PHENOXY
    • DTXSID0052380
    • ACETALDEHYDE, P-TOLYLOXY-
    • UNII-HQL6T929HS
    • 4-methylphenoxyacetaldehyde
    • 2-(p-Tolyloxy)acetaldehyde
    • para-methyl phenoxyacetaldehyde
    • SCHEMBL230017
    • DTXCID0030952
    • AKOS010078903
    • NS00012968
    • H11068
    • Q27280061
    • 267-317-6

  • Applications

    p-Methylphenoxyacetaldehyde (CAS 67845-46-9) is primarily used as an intermediate in fragrance chemistry, serving as a building block for the synthesis of aroma compounds and derivative esters/ethers; it is commonly evaluated as a precursor for flavor ingredients in research for multisensory formulations. In cosmetics and personal care, it may function as a fragrance intermediate in scented products; in household products, it can contribute to fragrance profiles when formulated. In polymer and plastics science, it is explored as a functionalized building block for specialty polymers and resin systems. Its use and handling are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 630.68
    methanol 751.36
    isopropanol 308.75
    water 3.52
    ethyl acetate 607.99
    n-propanol 359.69
    acetone 354.59
    n-butanol 251.72
    acetonitrile 595.2
    DMF 336.45
    toluene 128.81
    isobutanol 184.68
    1,4-dioxane 982.31
    methyl acetate 616.43
    THF 438.69
    2-butanone 324.17
    n-pentanol 155.77
    sec-butanol 204.19
    n-hexane 5.38
    ethylene glycol 263.02
    NMP 140.14
    cyclohexane 16.89
    DMSO 638.23
    n-butyl acetate 184.79
    n-octanol 47.08
    chloroform 689.01
    n-propyl acetate 189.94
    acetic acid 447.43
    dichloromethane 785.63
    cyclohexanone 251.79
    propylene glycol 259.71
    isopropyl acetate 168.19
    DMAc 339.08
    2-ethoxyethanol 425.92
    isopentanol 165.5
    n-heptane 10.62
    ethyl formate 295.61
    1,2-dichloroethane 509.55
    n-hexanol 157.9
    2-methoxyethanol 750.82
    isobutyl acetate 93.45
    tetrachloromethane 58.48
    n-pentyl acetate 58.6
    transcutol 1047.89
    n-heptanol 45.27
    ethylbenzene 59.53
    MIBK 99.56
    2-propoxyethanol 316.21
    tert-butanol 368.03
    MTBE 190.81
    2-butoxyethanol 123.58
    propionic acid 341.79
    o-xylene 75.68
    formic acid 260.73
    diethyl ether 293.58
    m-xylene 72.86
    p-xylene 69.6
    chlorobenzene 164.52
    dimethyl carbonate 135.71
    n-octane 4.32
    formamide 451.28
    cyclopentanone 238.11
    2-pentanone 193.67
    anisole 194.74
    cyclopentyl methyl ether 150.18
    gamma-butyrolactone 372.13
    1-methoxy-2-propanol 380.53
    pyridine 467.46
    3-pentanone 158.24
    furfural 403.29
    n-dodecane 5.09
    diethylene glycol 371.38
    diisopropyl ether 46.23
    tert-amyl alcohol 208.11
    acetylacetone 245.65
    n-hexadecane 5.69
    acetophenone 139.53
    methyl propionate 351.38
    isopentyl acetate 139.59
    trichloroethylene 822.45
    n-nonanol 44.24
    cyclohexanol 154.38
    benzyl alcohol 165.2
    2-ethylhexanol 79.99
    isooctanol 37.01
    dipropyl ether 105.42
    1,2-dichlorobenzene 135.54
    ethyl lactate 97.57
    propylene carbonate 205.49
    n-methylformamide 340.52
    2-pentanol 134.1
    n-pentane 6.66
    1-propoxy-2-propanol 177.91
    1-methoxy-2-propyl acetate 203.2
    2-(2-methoxypropoxy) propanol 165.9
    mesitylene 41.18
    ε-caprolactone 237.86
    p-cymene 39.47
    epichlorohydrin 616.99
    1,1,1-trichloroethane 327.39
    2-aminoethanol 350.87
    morpholine-4-carbaldehyde 379.93
    sulfolane 301.8
    2,2,4-trimethylpentane 7.09
    2-methyltetrahydrofuran 306.02
    n-hexyl acetate 87.53
    isooctane 5.51
    2-(2-butoxyethoxy)ethanol 220.72
    sec-butyl acetate 107.62
    tert-butyl acetate 146.01
    decalin 11.98
    glycerin 310.6
    diglyme 462.38
    acrylic acid 281.1
    isopropyl myristate 43.94
    n-butyric acid 346.06
    acetyl acetate 262.97
    di(2-ethylhexyl) phthalate 48.95
    ethyl propionate 174.17
    nitromethane 755.03
    1,2-diethoxyethane 270.89
    benzonitrile 167.76
    trioctyl phosphate 30.43
    1-bromopropane 197.32
    gamma-valerolactone 382.03
    n-decanol 36.45
    triethyl phosphate 71.13
    4-methyl-2-pentanol 60.96
    propionitrile 342.82
    vinylene carbonate 231.46
    1,1,2-trichlorotrifluoroethane 360.57
    DMS 143.78
    cumene 38.12
    2-octanol 26.39
    2-hexanone 127.18
    octyl acetate 52.47
    limonene 54.75
    1,2-dimethoxyethane 527.06
    ethyl orthosilicate 67.74
    tributyl phosphate 44.22
    diacetone alcohol 179.72
    N,N-dimethylaniline 100.56
    acrylonitrile 422.45
    aniline 208.05
    1,3-propanediol 416.47
    bromobenzene 163.8
    dibromomethane 402.83
    1,1,2,2-tetrachloroethane 543.58
    2-methyl-cyclohexyl acetate 90.65
    tetrabutyl urea 57.33
    diisobutyl methanol 49.99
    2-phenylethanol 137.07
    styrene 87.51
    dioctyl adipate 76.54
    dimethyl sulfate 161.59
    ethyl butyrate 146.08
    methyl lactate 147.52
    butyl lactate 59.24
    diethyl carbonate 126.84
    propanediol butyl ether 113.25
    triethyl orthoformate 95.75
    p-tert-butyltoluene 37.31
    methyl 4-tert-butylbenzoate 100.48
    morpholine 867.88
    tert-butylamine 179.11
    n-dodecanol 30.76
    dimethoxymethane 348.45
    ethylene carbonate 201.67
    cyrene 121.88
    2-ethoxyethyl acetate 139.53
    2-ethylhexyl acetate 102.39
    1,2,4-trichlorobenzene 161.25
    4-methylpyridine 293.86
    dibutyl ether 70.68
    2,6-dimethyl-4-heptanol 49.99
    DEF 236.35
    dimethyl isosorbide 235.08
    tetrachloroethylene 320.35
    eugenol 110.87
    triacetin 135.74
    span 80 103.2
    1,4-butanediol 150.56
    1,1-dichloroethane 432.22
    2-methyl-1-pentanol 116.34
    methyl formate 286.48
    2-methyl-1-butanol 146.95
    n-decane 7.22
    butyronitrile 252.21
    3,7-dimethyl-1-octanol 59.54
    1-chlorooctane 31.85
    1-chlorotetradecane 16.31
    n-nonane 6.43
    undecane 5.9
    tert-butylcyclohexane 11.82
    cyclooctane 5.81
    cyclopentanol 141.53
    tetrahydropyran 466.65
    tert-amyl methyl ether 121.2
    2,5,8-trioxanonane 326.97
    1-hexene 41.0
    2-isopropoxyethanol 224.54
    2,2,2-trifluoroethanol 152.46
    methyl butyrate 209.55

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction