p-Mentha-1,2,4-triol (CAS 2514-92-3) is a hydroxyl-rich monoterpene triol valued mainly as a versatile intermediate and bio-based building block across flavor–fragrance, polymer materials, and applied chemistry R&D; owing to its facile esterification/etherification/oxidation/dehydration, it is used to access esters and ethers as slow-release pro-fragrances, odor modulators, and to fine-tune longevity, while also serving as a potential humectant/co-solvent/viscosity modifier in personal-care formulations (use contingent on safety assessment and regulatory compliance); as a bio-derived polyol, it can be incorporated into polyurethanes, polyesters, or cyclic carbonates for coatings, adhesives, and inks, where high –OH density enables hydrogen bonding and robust crosslinking; in pharmaceutical and agrochemical discovery, the p-menthane scaffold provides convenient chiral pool material for asymmetric synthesis and ester/urethane libraries for SAR exploration, and it functions as a precursor/marker for studying monoterpene biotransformations, optimizing green routes from renewable feedstocks (e.g., limonene/menthol), and generating related derivatives such as p-menthane diols for repellent or bioaroma research.
