p-(2-(Dimethylamino)ethoxy)benzylamine

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  • Identifiers

    CAS number
    20059-73-8

    Molecular formula
    C11H18N2O

    SMILES
    CN(C)CCOC1=CC=C(C=C1)CN

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 45.06%
    Sweet 35.56%
    Cheesy 35.3%
    Ripe 30.89%
    Animal 29.88%
    Odorless 23.71%
    Meaty 23.23%
    Savory 22.81%
    Grape 21.85%
    Cooling 20.7%

     

    Flavor
    Fruity 45.66%
    Sweet 39.83%
    Mild 37.21%
    Floral 35.89%
    Spicy 25.91%
    Meaty 23.29%
    Oily 23.03%
    Earthy 22.9%
    Herbal 22.87%
    Bitter 22.73%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.8

    pKa est.
    6.18 (neutral)

    Molecular weight
    194.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    311°C

    Flash point

    • 131.17 ˚C est.

  • Synonyms

    • 20059-73-8
    • p-(2-(Dimethylamino)ethoxy)benzylamine
    • 4-[2-(Dimethylamino)ethoxy]benzenemethanamine
    • EINECS 243-491-9
    • P-[2-(dimethylamino)ethoxy]benzylamine
    • DTXSID10173870
    • 4-(2-(Dimethylamino)ethoxy)benzenemethanamine
    • RefChem:857920
    • DTXCID9096361
    • 243-491-9
    • 4-[2-(Dimethylamino)ethoxy]benzylamine
    • 2-(4-(Aminomethyl)phenoxy)-N,N-dimethylethanamine
    • MFCD01075231
    • BENZENEMETHANAMINE, 4-[2-(DIMETHYLAMINO)ETHOXY]-
    • 2-[4-(aminomethyl)phenoxy]-N,N-dimethylethanamine
    • {4-[2-(dimethylamino)ethoxy]phenyl}methanamine
    • 4-(2-dimethylamino)-ethoxybenzylamine
    • [2-(4-aminomethyl-phenoxy)-ethyl]-dimethyl-amine
    • 4-[2-(dimethylamino) ethoxy] benzylamine
    • CHEMBL5218544
    • 4-(2-(dimethylamino)ethoxy)benzylamine
    • 4-(2-dimethylamino)ethoxy-benzylamine
    • (4-[2-(dimethylamino)ethoxy]phenyl)methanamine
    • 2-(4-(aminomethyl)phenoxy)-N,N-dimethylethan-1-amine
    • 2-[4-(Aminomethyl)phenoxy]-N,N-dimethylethan-1-amine
    • Itopride Impurity 3
    • SCHEMBL110426
    • 45X4TW4GP8
    • orb3031171
    • SCHEMBL4607528
    • CHEBI:194737
    • 4-(2-dimethylaminoethoxy)benzylamine
    • BDBM50607322
    • SBB077300
    • 4-(2-dimethylaminoethoxy)benzyl amine
    • AKOS000131378
    • CS-W002738
    • MB01683
    • 4-(2-dimethylamino)-ethoxy-benzylamine
    • 4-[2-(dimethylamino)ethoxy] benzylamine
    • 4-[2-(dimethylamino)ethoxy]-benzylamine
    • 4-[2-(dimethylamino)ethoxy]benzyl amine
    • AC-15247
    • DS-16636
    • SY005516
    • 4-[(2-dimethylamino) ethoxy] benzylamine
    • DB-045073
    • NS00026511
    • EN300-43395
    • {2-[4-(aminomethyl)phenoxy]ethyl}dimethylamine
    • 059D738
    • 4-(2-dimethylamino)-ethoxybenzylamine, AldrichCPR
    • F036397
    • 2-[4-(aminomethyl)phenoxy]-N,N-dimethyl-ethanamine
    • n-(2-[4-(aminomethyl)phenoxy]ethyl)-n,n-dimethylamine
    • 2-(4-(Aminomethyl)phenoxy)-N pound notN-dimethylethanamine
    • 20059-73-8

  • Applications

    p-(2-(Dimethylamino)ethoxy)benzylamine, CAS number: 20059-73-8, is primarily used as an organic synthetic intermediate for amine-containing compounds. It serves as a building block in medicinal chemistry for the preparation of pharmaceutical and bioactive leads, and is also evaluated for use in agrochemical synthesis. The molecule’s benzylamine moiety and dimethylaminoethoxy substituent enable further functionalization, supporting applications in polymers and plastics as a functionalized monomer or pendant group. It is used as an intermediate in coatings, inks and adhesives formulations to introduce reactive amine sites that can react with epoxies or isocyanates. In fragrance and flavor chemistry, it may be used as a precursor to more complex fragrance molecules, and in general serves as a selectable synthetic building block in chemical libraries. Its use is typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 705.13
    methanol 1322.59
    isopropanol 159.66
    water 323.89
    ethyl acetate 88.35
    n-propanol 369.18
    acetone 54.9
    n-butanol 234.72
    acetonitrile 101.4
    DMF 367.93
    toluene 14.08
    isobutanol 172.62
    1,4-dioxane 233.24
    methyl acetate 98.2
    THF 115.56
    2-butanone 43.41
    n-pentanol 115.44
    sec-butanol 107.92
    n-hexane 2.41
    ethylene glycol 903.53
    NMP 215.93
    cyclohexane 8.9
    DMSO 490.23
    n-butyl acetate 48.38
    n-octanol 15.88
    chloroform 316.56
    n-propyl acetate 45.26
    acetic acid 2090.82
    dichloromethane 278.86
    cyclohexanone 124.12
    propylene glycol 571.15
    isopropyl acetate 28.6
    DMAc 273.78
    2-ethoxyethanol 491.53
    isopentanol 97.09
    n-heptane 3.37
    ethyl formate 186.56
    1,2-dichloroethane 124.67
    n-hexanol 104.36
    2-methoxyethanol 997.28
    isobutyl acetate 27.46
    tetrachloromethane 58.06
    n-pentyl acetate 16.68
    transcutol 497.18
    n-heptanol 34.41
    ethylbenzene 5.95
    MIBK 13.36
    2-propoxyethanol 334.78
    tert-butanol 121.09
    MTBE 26.36
    2-butoxyethanol 139.42
    propionic acid 568.0
    o-xylene 14.73
    formic acid 2347.06
    diethyl ether 34.19
    m-xylene 11.87
    p-xylene 10.57
    chlorobenzene 46.74
    dimethyl carbonate 46.71
    n-octane 1.02
    formamide 1568.18
    cyclopentanone 102.81
    2-pentanone 25.64
    anisole 27.14
    cyclopentyl methyl ether 49.98
    gamma-butyrolactone 252.49
    1-methoxy-2-propanol 309.11
    pyridine 155.53
    3-pentanone 28.51
    furfural 382.35
    n-dodecane 0.76
    diethylene glycol 573.08
    diisopropyl ether 5.28
    tert-amyl alcohol 88.11
    acetylacetone 50.59
    n-hexadecane 0.82
    acetophenone 41.82
    methyl propionate 80.52
    isopentyl acetate 37.21
    trichloroethylene 330.18
    n-nonanol 15.36
    cyclohexanol 137.38
    benzyl alcohol 84.46
    2-ethylhexanol 36.13
    isooctanol 21.95
    dipropyl ether 23.63
    1,2-dichlorobenzene 53.66
    ethyl lactate 75.15
    propylene carbonate 161.96
    n-methylformamide 513.85
    2-pentanol 53.74
    n-pentane 3.7
    1-propoxy-2-propanol 135.54
    1-methoxy-2-propyl acetate 72.36
    2-(2-methoxypropoxy) propanol 75.59
    mesitylene 7.76
    ε-caprolactone 155.59
    p-cymene 9.44
    epichlorohydrin 210.56
    1,1,1-trichloroethane 80.62
    2-aminoethanol 1048.69
    morpholine-4-carbaldehyde 348.77
    sulfolane 257.14
    2,2,4-trimethylpentane 2.62
    2-methyltetrahydrofuran 77.1
    n-hexyl acetate 20.6
    isooctane 1.16
    2-(2-butoxyethoxy)ethanol 132.55
    sec-butyl acetate 20.67
    tert-butyl acetate 26.29
    decalin 2.61
    glycerin 975.39
    diglyme 266.1
    acrylic acid 661.62
    isopropyl myristate 7.62
    n-butyric acid 531.23
    acetyl acetate 89.6
    di(2-ethylhexyl) phthalate 25.09
    ethyl propionate 35.45
    nitromethane 930.64
    1,2-diethoxyethane 53.4
    benzonitrile 58.5
    trioctyl phosphate 13.5
    1-bromopropane 31.62
    gamma-valerolactone 311.03
    n-decanol 11.5
    triethyl phosphate 35.29
    4-methyl-2-pentanol 21.6
    propionitrile 69.84
    vinylene carbonate 202.28
    1,1,2-trichlorotrifluoroethane 705.47
    DMS 40.68
    cumene 6.34
    2-octanol 10.04
    2-hexanone 21.66
    octyl acetate 12.48
    limonene 13.92
    1,2-dimethoxyethane 237.87
    ethyl orthosilicate 35.97
    tributyl phosphate 18.92
    diacetone alcohol 64.47
    N,N-dimethylaniline 22.58
    acrylonitrile 125.6
    aniline 96.81
    1,3-propanediol 917.35
    bromobenzene 32.06
    dibromomethane 120.87
    1,1,2,2-tetrachloroethane 262.89
    2-methyl-cyclohexyl acetate 38.15
    tetrabutyl urea 21.59
    diisobutyl methanol 12.9
    2-phenylethanol 74.28
    styrene 9.21
    dioctyl adipate 22.34
    dimethyl sulfate 87.46
    ethyl butyrate 40.62
    methyl lactate 137.55
    butyl lactate 39.33
    diethyl carbonate 38.45
    propanediol butyl ether 96.53
    triethyl orthoformate 42.69
    p-tert-butyltoluene 9.23
    methyl 4-tert-butylbenzoate 40.99
    morpholine 358.31
    tert-butylamine 50.87
    n-dodecanol 9.11
    dimethoxymethane 109.58
    ethylene carbonate 159.09
    cyrene 101.72
    2-ethoxyethyl acetate 45.06
    2-ethylhexyl acetate 27.37
    1,2,4-trichlorobenzene 78.13
    4-methylpyridine 81.11
    dibutyl ether 10.37
    2,6-dimethyl-4-heptanol 12.9
    DEF 103.84
    dimethyl isosorbide 115.13
    tetrachloroethylene 254.48
    eugenol 63.09
    triacetin 47.52
    span 80 73.52
    1,4-butanediol 354.85
    1,1-dichloroethane 68.35
    2-methyl-1-pentanol 62.27
    methyl formate 302.92
    2-methyl-1-butanol 118.41
    n-decane 1.14
    butyronitrile 64.8
    3,7-dimethyl-1-octanol 14.92
    1-chlorooctane 4.87
    1-chlorotetradecane 2.51
    n-nonane 1.01
    undecane 0.88
    tert-butylcyclohexane 2.08
    cyclooctane 2.67
    cyclopentanol 135.97
    tetrahydropyran 94.24
    tert-amyl methyl ether 23.14
    2,5,8-trioxanonane 168.24
    1-hexene 7.43
    2-isopropoxyethanol 163.58
    2,2,2-trifluoroethanol 772.23
    methyl butyrate 59.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction