Oxymetholone

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  • Identifiers

    CAS number
    434-07-1

    Molecular formula
    C21H32O3

    SMILES
    C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(C/C(=C/O)/C(=O)C4)C

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Woody 75.59%
    Cedar 41.33%
    Balsamic 40.52%
    Herbal 40.29%
    Amber 39.2%
    Spicy 38.26%
    Camphoreous 37.56%
    Dry 35.38%
    Mint 33.33%
    Pine 33.1%

    Scent© AI

  • Properties

    XLogP3-AA
    4.4

    Molecular weight
    332.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    431°C

    Melting point expt.

    • 352 to 356 °F (NTP, 1992)
    • 178°C to 180°C
    • 185-190 °C

    Flash point est.
    217.74 ˚C

    Solubility expt.

    • less than 1 mg/mL at 73 °F (NTP, 1992)
    • 5.21 mg/L
    • Practically insol in water; sol in ethanol, dioxane, ether; very sol in chloroform

  • Synonyms

    • oxymetholone
    • 434-07-1
    • Protanabol
    • Anapolon
    • Anasteron
    • Nastenon
    • Oximetolona
    • Anadrol-50
    • Adroyd
    • Anadrol
    • Oxymethalone
    • Oxymethenolone
    • Plenastril
    • Synasteron
    • Adroidin
    • Roboral
    • Oximetholonum
    • Oxymetholonum
    • Anadroyd
    • Dynasten
    • Methabol
    • Oximetalonu
    • Pardroyd
    • Pavisoid
    • Zenalosyn
    • Becorel
    • Oxitosona-50
    • Anasteronal
    • CI-406
    • Ossimetolone
    • Oxymetholone ciii
    • NSC-26,198
    • Anasterone
    • CCRIS 492
    • Oximetholone
    • HSDB 3374
    • UNII-L76T0ZCA8K
    • Oximetolona [INN-Spanish]
    • Oxymetholonum [INN-Latin]
    • EINECS 207-098-6
    • L76T0ZCA8K
    • 17-Hydroxy-5-alpha-androstan-3-one
    • CI 406
    • DTXSID5023794
    • HMD
    • 2-Hydroxymethylene-17alpha-methyldihydrotestosterone
    • NSC-26198
    • 4,5alpha-Dihydro-2-hydroxymethylene-17alpha-methyltestosterone
    • 2-Hydroxymethylene-17alpha-methyl-5alpha-androstan-17beta-ol-3-one
    • 17alpha-Methyl-2-hydroxymethylene-17-hydroxy-5alpha-androstan-3-one
    • 17-Hydroxy-2-(hydroxymethylene)-17-methyl-5-alpha-17-beta-androst-3-one
    • 2-Hydroxymethylene-17alpha-methyl-17beta-hydroxy-5alpha-androstan-3-one
    • 2-Hydroxymethylene-17-alpha-methyl-dihydrotestosterone
    • CHEBI:7864
    • DTXCID003794
    • 2-Hydroxymethylene-17alpha-methylandrostan-17beta-ol-3-one
    • 4,5-Dihydro-2-hydroxymethylene-17-alpha-methyltestosterone
    • NIOSH/BV8059400
    • 2-Hydroxymethylene-17alpha-methyl-17beta-hydroxy-3-adrostanone
    • 17-beta-Hydroxy-2-hydroxymethylene-17-alpha-methyl-3-androstanone
    • 2-Hydroxymethylene-17-alpha-methyl-17-beta-hydroxy-3-androstanone
    • 17-alpha-Methyl-2-hydroxymethylene-17-hydroxy-5-alpha-androstan-3-one
    • 2-Hydroxymethylene-17-alpha-methyl-5-alpha-androstan-17-beta-ol-3-one
    • 5alpha-Androstan-3-one, 17beta-hydroxy-2-(hydroxymethylene)-17-methyl-
    • 17-beta-Hydroxy-2-(hydroxymethylene)-17-alpha-methyl-5-alpha-androstan-3-one
    • Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5alpha,17beta)-
    • Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (alpha,17beta)-
    • NCGC00091430-01
    • Oxymetholone [USAN:USP:INN:BAN:JAN]
    • Hydroxymetholone
    • BV80594000
    • 5-alpha,17-beta-Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-
    • 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-(hydroxymethylene)-17-methyl-
    • Androstano(2,3-c)(1,2,5)oxadiazol-17-ol, 17-methyl-, (5-alpha,17-beta)-
    • Oximetolona (INN-Spanish)
    • Oxymetholonum (INN-Latin)
    • 17beta-Hydroxy-2-(hydroxymethylene)-17-methyl-5alpha-androstan-3-one
    • Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5-alpha,17-beta)-
    • Anapolon 50
    • OXYMETHOLONE (MART.)
    • OXYMETHOLONE [MART.]
    • (2Z,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2-(hydroxymethylidene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
    • Ossimetolone [DCIT]
    • 2-Hydroxymethyleneandrostan-17-beta-ol-17-alpha-methyl-3-one
    • OXYMETHOLONE CIII (USP-RS)
    • OXYMETHOLONE CIII [USP-RS]
    • 17beta-Hydroxy-2-hydroxymethylidene-17alpha-methyl-3-androstanone
    • OXYMETHOLONE (USP MONOGRAPH)
    • OXYMETHOLONE [USP MONOGRAPH]
    • (5alpha,17beta)-17-hydroxy-2-(hydroxymethylidene)-17-methylandrostan-3-one
    • 17beta-hydroxy-2-(hydroxymethylidene)-17-methyl-5alpha-androstan-3-one
    • Androstan-3-one, 17-beta-hydroxy-2-(hydroxymethylene)-17-alpha-methyl-
    • Oxymetholone (1mg/ml in Acetonitrile)
    • Oxymetholone (USAN:USP:INN:BAN:JAN)
    • (5S,8R,9S,10S,13S,14S,17S,Z)-17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
    • CAS-434-07-1
    • STANOZOLOL IMPURITY B (EP IMPURITY)
    • STANOZOLOL IMPURITY B [EP IMPURITY]
    • oxymetholon
    • Hemogenin
    • Oxitosona
    • Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5.alpha.,17.beta.)-
    • ANAPALON
    • OXIMETHOLONIUM
    • Anadrol-50 (TN)
    • SYNASTERON 50
    • ANAPOLAN 50
    • OXYMETHOLONE [MI]
    • OXYMETHOLONE [INN]
    • OXYMETHOLONE [JAN]
    • OXYMETHOLONE [HSDB]
    • OXYMETHOLONE [USAN]
    • OXYMETHOLONE [VANDF]
    • OXYMETHOLONE [WHO-DD]
    • SCHEMBL145158
    • SCHEMBL145160
    • CHEMBL1200585
    • CHEMBL1578149
    • Oxymetholone (JP17/USP/INN)
    • ICMWWNHDUZJFDW-DHODBPELSA-N
    • GLXC-04661
    • OXYMETHOLONE [ORANGE BOOK]
    • Tox21_111131
    • Tox21_200071
    • BDBM50248303
    • CL-406
    • Oxymetholone, 1mg/ml in Acetonitrile
    • AKOS027473312

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 59.9
    methanol 73.96
    isopropanol 47.81
    water 0.65
    ethyl acetate 52.52
    n-propanol 53.43
    acetone 88.22
    n-butanol 43.42
    acetonitrile 36.71
    DMF 176.75
    toluene 50.91
    isobutanol 23.79
    1,4-dioxane 143.63
    methyl acetate 32.42
    THF 334.56
    2-butanone 40.35
    n-pentanol 10.13
    sec-butanol 7.78
    n-hexane 0.38
    ethylene glycol 12.85
    NMP 32.61
    cyclohexane 1.74
    DMSO 101.67
    n-butyl acetate 29.26
    n-octanol 6.3
    chloroform 148.55
    n-propyl acetate 22.05
    acetic acid 43.62
    dichloromethane 75.44
    cyclohexanone 65.11
    propylene glycol 12.3
    isopropyl acetate 49.09
    DMAc 69.41
    2-ethoxyethanol 45.43
    isopentanol 28.41
    n-heptane 0.5
    ethyl formate 24.31
    1,2-dichloroethane 43.59
    n-hexanol 20.8
    2-methoxyethanol 140.84
    isobutyl acetate 19.19
    tetrachloromethane 15.97
    n-pentyl acetate 23.14
    transcutol 147.88
    n-heptanol 13.82
    ethylbenzene 11.28
    MIBK 39.48
    2-propoxyethanol 105.81
    tert-butanol 33.91
    MTBE 13.41
    2-butoxyethanol 52.64
    propionic acid 23.47
    o-xylene 16.72
    formic acid 28.63
    diethyl ether 29.29
    m-xylene 27.52
    p-xylene 14.11
    chlorobenzene 40.89
    dimethyl carbonate 46.95
    n-octane 0.29
    formamide 61.12
    cyclopentanone 104.26
    2-pentanone 46.67
    anisole 38.4
    cyclopentyl methyl ether 46.15
    gamma-butyrolactone 99.71
    1-methoxy-2-propanol 120.96
    pyridine 107.38
    3-pentanone 28.2
    furfural 92.99
    n-dodecane 0.22
    diethylene glycol 87.29
    diisopropyl ether 7.82
    tert-amyl alcohol 7.52
    acetylacetone 96.9
    n-hexadecane 0.28
    acetophenone 35.43
    methyl propionate 46.32
    isopentyl acetate 32.59
    trichloroethylene 115.53
    n-nonanol 7.74
    cyclohexanol 17.47
    benzyl alcohol 33.6
    2-ethylhexanol 8.84
    isooctanol 10.93
    dipropyl ether 12.84
    1,2-dichlorobenzene 34.63
    ethyl lactate 21.29
    propylene carbonate 48.23
    n-methylformamide 80.74
    2-pentanol 12.5
    n-pentane 0.69
    1-propoxy-2-propanol 60.12
    1-methoxy-2-propyl acetate 78.31
    2-(2-methoxypropoxy) propanol 37.82
    mesitylene 13.98
    ε-caprolactone 49.7
    p-cymene 7.42
    epichlorohydrin 121.51
    1,1,1-trichloroethane 41.24
    2-aminoethanol 33.27
    morpholine-4-carbaldehyde 90.81
    sulfolane 84.57
    2,2,4-trimethylpentane 0.34
    2-methyltetrahydrofuran 42.08
    n-hexyl acetate 21.46
    isooctane 0.56
    2-(2-butoxyethoxy)ethanol 54.77
    sec-butyl acetate 17.81
    tert-butyl acetate 49.36
    decalin 0.85
    glycerin 33.98
    diglyme 113.0
    acrylic acid 26.93
    isopropyl myristate 8.78
    n-butyric acid 54.21
    acetyl acetate 51.58
    di(2-ethylhexyl) phthalate 14.89
    ethyl propionate 25.02
    nitromethane 97.33
    1,2-diethoxyethane 33.0
    benzonitrile 38.22
    trioctyl phosphate 9.8
    1-bromopropane 14.19
    gamma-valerolactone 166.86
    n-decanol 4.89
    triethyl phosphate 14.68
    4-methyl-2-pentanol 12.52
    propionitrile 38.13
    vinylene carbonate 59.86
    1,1,2-trichlorotrifluoroethane 78.83
    DMS 34.9
    cumene 6.42
    2-octanol 5.66
    2-hexanone 16.94
    octyl acetate 10.35
    limonene 6.72
    1,2-dimethoxyethane 86.96
    ethyl orthosilicate 13.8
    tributyl phosphate 9.78
    diacetone alcohol 52.89
    N,N-dimethylaniline 20.66
    acrylonitrile 58.48
    aniline 58.41
    1,3-propanediol 68.42
    bromobenzene 38.27
    dibromomethane 41.11
    1,1,2,2-tetrachloroethane 83.25
    2-methyl-cyclohexyl acetate 21.88
    tetrabutyl urea 13.29
    diisobutyl methanol 7.46
    2-phenylethanol 45.18
    styrene 14.68
    dioctyl adipate 15.33
    dimethyl sulfate 57.95
    ethyl butyrate 23.32
    methyl lactate 39.13
    butyl lactate 27.34
    diethyl carbonate 18.65
    propanediol butyl ether 32.5
    triethyl orthoformate 21.16
    p-tert-butyltoluene 7.9
    methyl 4-tert-butylbenzoate 38.9
    morpholine 128.51
    tert-butylamine 12.23
    n-dodecanol 3.05
    dimethoxymethane 188.75
    ethylene carbonate 53.27
    cyrene 39.76
    2-ethoxyethyl acetate 48.43
    2-ethylhexyl acetate 21.03
    1,2,4-trichlorobenzene 41.14
    4-methylpyridine 76.29
    dibutyl ether 5.93
    2,6-dimethyl-4-heptanol 7.46
    DEF 32.49
    dimethyl isosorbide 72.99
    tetrachloroethylene 58.7
    eugenol 43.96
    triacetin 36.47
    span 80 28.35
    1,4-butanediol 12.43
    1,1-dichloroethane 40.65
    2-methyl-1-pentanol 7.51
    methyl formate 49.05
    2-methyl-1-butanol 13.16
    n-decane 0.47
    butyronitrile 32.93
    3,7-dimethyl-1-octanol 7.89
    1-chlorooctane 2.6
    1-chlorotetradecane 0.88
    n-nonane 0.37
    undecane 0.3
    tert-butylcyclohexane 0.67
    cyclooctane 0.65
    cyclopentanol 21.22
    tetrahydropyran 76.42
    tert-amyl methyl ether 7.09
    2,5,8-trioxanonane 67.57
    1-hexene 1.94
    2-isopropoxyethanol 27.81
    2,2,2-trifluoroethanol 28.85
    methyl butyrate 25.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction