Oxygen difluoride

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  • Identifiers

    CAS number
    7783-41-7

    Molecular formula
    F2O

    SMILES
    O(F)F

    Safety labels

    Oxidizer
    Oxidizer

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 56.49%
    Fishy 29.33%
    Alcoholic 22.8%
    Ethereal 22.02%
    Sulfurous 18.38%
    Sweet 18.3%
    Ripe 18.08%
    Cheesy 17.82%
    Fresh 17.13%
    Meaty 16.5%

     

    Flavor
    Odorless 44.3%
    Sulfurous 28.82%
    Fishy 26.62%
    Pungent 23.68%
    Sulfury 23.32%
    Very slight 20.88%
    Rotten 20.32%
    Mousy 20.21%
    Formyl 20.13%
    Decomposing cabbage 20.07%

     

    Odor impact est.
    Low

    Odor threshold

    • Odor Threshold Low: 0.09 [ppm]. Odor threshold from AIHA
    • An odor threshold of 0.1 ppm has been reported.
    • Low odor threshold= 0.2 mg/cu m; High odor threshold= 1.0 mg/cu m

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    0.43 (strong acid)

    Molecular weight
    53.996 g/mol

    Melting point expt.

    • -371 °F (NIOSH, 2024)
    • -223.8 °C
    • -224 °C
    • -371 °F

    Boiling point

    • -230 °F at 760 mmHg (NIOSH, 2024)
    • -144.75 °C
    • -145 °C
    • -230 °F

    Flash point

    • 15.83 ˚C est.

    Solubility expt.

    • 0.02 % (NIOSH, 2024)
    • 6.8 ML GAS/100 ML WATER @ 0 °C
    • INSOL IN HOT WATER; SLIGHTLY SOL IN ALKALI & ACID
    • SLIGHTLY SOL IN WATER
    • Slightly sol in alcohol
    • Solubility in water, ml/100ml at 0 °C: 6.8 (reacts slowly)
    • 0.02%

  • Synonyms

    • Oxygen difluoride
    • Difluorine monoxide
    • Fluorine oxide
    • Oxygen fluoride
    • FLUORINE MONOXIDE
    • Oxydifluoride
    • Oxygen fluoride (OF2)
    • Fluorine (di-)oxide
    • 7783-41-7
    • difluorene monoxide
    • difluoridooxygen
    • HSDB 2525
    • EINECS 231-996-7
    • UNII-7BCS2CW398
    • UN2190
    • Difluorine monooxide
    • [OF2]
    • Oxygen difluoride, compressed
    • FLUORINE MONOXIDE [MI]
    • 7BCS2CW398
    • FLUORINE MONOXIDE [HSDB]
    • CHEBI:30494
    • DTXSID20894009
    • UN 2190
    • OF2
    • (OF2)
    • Difluorure d'oxygene
    • Difluorure d'oxygene [French]
    • Difluoruro de oxigeno
    • Difluoruro de oxigeno [Spanish]
    • oxyfluoride
    • fluorine oxides
    • Sauerstoffdifluorid
    • Fluorine (di)oxide
    • DIFLUORINE OXIDE
    • FLUORINE OXIDE (F2O)
    • FLUORINE MONOXIDE (F2O)
    • CHEBI:37752
    • Oxygen difluoride (ACGIH:OSHA)
    • DTXCID001324053
    • Q411301
    • Oxygen difluoride, compressed [UN2190] [Poison gas]

  • Applications

    Oxygen difluoride (CAS 7783-41-7) is a highly reactive fluorinating agent used mainly to introduce fluorine into organic substrates, yielding organofluorine intermediates for chemical synthesis. It also finds use in the production of fluorinated polymers and coatings, where fluorination with OF2 helps deliver high-performance materials with enhanced properties. In electronics and semiconductor manufacturing, OF2 is evaluated for controlled surface modification and fluorination/etching of oxide- or carbon-containing surfaces under strict safety controls. It may serve as a fluorine source in the synthesis of specialty reagents and advanced material building blocks. Because of its extreme reactivity and toxicity, its use is confined to specialized facilities with appropriate handling and regulatory compliance.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 137.37
    methanol 219.08
    isopropanol 122.48
    water 39.68
    ethyl acetate 40.03
    n-propanol 89.55
    acetone 115.98
    n-butanol 74.76
    acetonitrile 81.28
    DMF 492.33
    toluene 14.0
    isobutanol 66.05
    1,4-dioxane 99.29
    methyl acetate 59.92
    THF 148.55
    2-butanone 59.47
    n-pentanol 47.53
    sec-butanol 76.55
    n-hexane 6.89
    ethylene glycol 102.66
    NMP 234.26
    cyclohexane 5.78
    DMSO 475.62
    n-butyl acetate 22.83
    n-octanol 28.59
    chloroform 29.53
    n-propyl acetate 25.49
    acetic acid 135.56
    dichloromethane 40.32
    cyclohexanone 51.55
    propylene glycol 80.71
    isopropyl acetate 27.3
    DMAc 271.81
    2-ethoxyethanol 93.66
    isopentanol 58.82
    n-heptane 6.66
    ethyl formate 48.54
    1,2-dichloroethane 38.16
    n-hexanol 34.74
    2-methoxyethanol 195.54
    isobutyl acetate 14.52
    tetrachloromethane 8.34
    n-pentyl acetate 23.48
    transcutol 109.83
    n-heptanol 27.16
    ethylbenzene 8.61
    MIBK 32.58
    2-propoxyethanol 76.11
    tert-butanol 145.22
    MTBE 68.23
    2-butoxyethanol 54.66
    propionic acid 70.68
    o-xylene 15.9
    formic acid 128.68
    diethyl ether 58.01
    m-xylene 13.46
    p-xylene 11.45
    chlorobenzene 14.74
    dimethyl carbonate 46.19
    n-octane 3.38
    formamide 164.98
    cyclopentanone 85.13
    2-pentanone 48.76
    anisole 29.76
    cyclopentyl methyl ether 50.9
    gamma-butyrolactone 100.26
    1-methoxy-2-propanol 143.43
    pyridine 63.63
    3-pentanone 36.68
    furfural 97.76
    n-dodecane 3.4
    diethylene glycol 86.58
    diisopropyl ether 17.92
    tert-amyl alcohol 91.5
    acetylacetone 49.77
    n-hexadecane 3.49
    acetophenone 28.63
    methyl propionate 51.12
    isopentyl acetate 20.88
    trichloroethylene 42.59
    n-nonanol 25.76
    cyclohexanol 44.67
    benzyl alcohol 30.43
    2-ethylhexanol 19.09
    isooctanol 21.44
    dipropyl ether 27.81
    1,2-dichlorobenzene 14.21
    ethyl lactate 27.84
    propylene carbonate 45.01
    n-methylformamide 176.62
    2-pentanol 50.56
    n-pentane 10.13
    1-propoxy-2-propanol 52.72
    1-methoxy-2-propyl acetate 31.52
    2-(2-methoxypropoxy) propanol 50.96
    mesitylene 10.43
    ε-caprolactone 46.01
    p-cymene 9.64
    epichlorohydrin 82.17
    1,1,1-trichloroethane 21.24
    2-aminoethanol 118.14
    morpholine-4-carbaldehyde 178.97
    sulfolane 144.05
    2,2,4-trimethylpentane 5.95
    2-methyltetrahydrofuran 75.49
    n-hexyl acetate 29.9
    isooctane 4.47
    2-(2-butoxyethoxy)ethanol 65.13
    sec-butyl acetate 16.5
    tert-butyl acetate 33.5
    decalin 3.88
    glycerin 115.1
    diglyme 106.28
    acrylic acid 80.82
    isopropyl myristate 16.15
    n-butyric acid 58.61
    acetyl acetate 24.66
    di(2-ethylhexyl) phthalate 19.1
    ethyl propionate 27.48
    nitromethane 166.11
    1,2-diethoxyethane 36.63
    benzonitrile 27.17
    trioctyl phosphate 16.16
    1-bromopropane 25.14
    gamma-valerolactone 108.31
    n-decanol 20.83
    triethyl phosphate 16.16
    4-methyl-2-pentanol 30.56
    propionitrile 53.48
    vinylene carbonate 42.07
    1,1,2-trichlorotrifluoroethane 83.01
    DMS 26.66
    cumene 8.52
    2-octanol 21.78
    2-hexanone 28.57
    octyl acetate 21.83
    limonene 13.72
    1,2-dimethoxyethane 133.43
    ethyl orthosilicate 15.79
    tributyl phosphate 16.48
    diacetone alcohol 60.06
    N,N-dimethylaniline 32.76
    acrylonitrile 72.41
    aniline 35.13
    1,3-propanediol 109.8
    bromobenzene 10.93
    dibromomethane 26.61
    1,1,2,2-tetrachloroethane 41.8
    2-methyl-cyclohexyl acetate 17.98
    tetrabutyl urea 27.35
    diisobutyl methanol 16.88
    2-phenylethanol 25.67
    styrene 11.09
    dioctyl adipate 22.31
    dimethyl sulfate 80.01
    ethyl butyrate 21.53
    methyl lactate 55.98
    butyl lactate 26.61
    diethyl carbonate 16.5
    propanediol butyl ether 57.72
    triethyl orthoformate 19.22
    p-tert-butyltoluene 10.68
    methyl 4-tert-butylbenzoate 39.51
    morpholine 127.28
    tert-butylamine 84.7
    n-dodecanol 17.19
    dimethoxymethane 168.23
    ethylene carbonate 34.56
    cyrene 44.45
    2-ethoxyethyl acetate 31.19
    2-ethylhexyl acetate 16.07
    1,2,4-trichlorobenzene 18.21
    4-methylpyridine 57.19
    dibutyl ether 21.76
    2,6-dimethyl-4-heptanol 16.88
    DEF 88.79
    dimethyl isosorbide 60.69
    tetrachloroethylene 29.27
    eugenol 44.51
    triacetin 30.65
    span 80 44.87
    1,4-butanediol 51.69
    1,1-dichloroethane 30.16
    2-methyl-1-pentanol 35.92
    methyl formate 118.85
    2-methyl-1-butanol 55.04
    n-decane 4.43
    butyronitrile 47.84
    3,7-dimethyl-1-octanol 22.71
    1-chlorooctane 11.98
    1-chlorotetradecane 7.09
    n-nonane 4.17
    undecane 3.81
    tert-butylcyclohexane 4.32
    cyclooctane 2.65
    cyclopentanol 63.02
    tetrahydropyran 63.8
    tert-amyl methyl ether 51.41
    2,5,8-trioxanonane 83.47
    1-hexene 17.22
    2-isopropoxyethanol 58.05
    2,2,2-trifluoroethanol 57.77
    methyl butyrate 36.08

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction