Oxine-copper

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  • Identifiers

    CAS number
    10380-28-6

    Molecular formula
    C18H12CuN2O2

    SMILES
    C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 42.78%
    Sweet 41.44%
    Animal 41.42%
    Burnt 37.8%
    Fruity 33.61%
    Musty 29.82%
    Bitter 26.73%
    Floral 26.62%
    Powdery 26.21%
    Smoky 24.21%

     

    Flavor
    Bitter 72.77%
    Fecal 28.1%
    Very strong 25.67%
    Indole 25.38%
    Animal 24.65%
    Moth ball 23.73%
    Naphthelene 23.22%
    Cereal 22.48%
    Nitrile 22.25%
    Flat 21.75%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    6.0 (weak acid)

    Molecular weight
    351.8 g/mol

    Flash point

    • 120.78 ˚C est.
    • Flash Point > 200 °C

    Solubility expt.

    • Solubility in water: none

  • Synonyms

    • Oxine-copper
    • 10380-28-6
    • Oxine copper
    • Copper 8-hydroxyquinoline
    • Copper-oxine
    • 8-hydroxyquinoline copper salt
    • Copper 8-quinolate
    • Copper 8-quinolinol
    • Bis(8-quinolinolato)copper(II)
    • Cellu-quin
    • Copper 8-quinolinolate
    • Oxine-copper [ISO]
    • Copper 8-hydroxyquinolate
    • Copper(II) 8-hydroxyquinolinate
    • Bis(8-oxyquinoline)copper
    • Copper-8
    • Bis(8-quinolinolato)copper
    • Copper 8-hydroxyquinolinate
    • Caswell No. 253
    • Cupric 8-quinolinolate
    • Bis(8-hydroxyquinolinato)copper
    • Oxine-cuivre
    • Bis(8-quinolinato)copper
    • Copper bis(8-hydroxyquinolinate)
    • Cupric 8-hydroxyquinolate
    • 8-Quinolinol, copper salt
    • Oxine-copper [BSI:ISO]
    • Oxine-cuivre [ISO-French]
    • CUPRIC 8-OXYQUINOLINE
    • NSC 7720
    • 8-Quinolinol, copper (II) chelate
    • Copper-8-hydroxyquinoline
    • Copper 8-quinolinolate (1:2)
    • EINECS 233-841-9
    • Bis(quinolin-8-olato)copper (IUPAC)
    • EPA Pesticide Chemical Code 024002
    • Copper, bis(8-quinolinolato-N1,O8)-
    • W8YEE02477
    • NSC-7720
    • Copper, bis(8-quinolinolato-.kappa.N1,.kappa.O8)-
    • UNII-W8YEE02477
    • AI3-26537
    • CCRIS 8219
    • COPPER 8-HYDROXYQUINOLINE [IARC]
    • Bis(8-quinolinato-N1'O8)copper
    • 8-HYDROXYQUINOLINE COPPER(2+) SALT
    • Copper, bis(8-quinolinolato-N(sup 1),O(sup 8))-
    • Copper, bis(8-quinolinolato-kappaN1,kappaO8)-
    • Oxine-cuivre (ISO-French)
    • COPPER 8-HYDROXYQUINOLINE (IARC)
    • Cu 8Q
    • oxinecopper
    • Copperoxine
    • Oxinecuivre
    • Celluquin
    • Copper8
    • Copper 8quinolate
    • Copper 8quinolinol
    • Copper 8quinolinolate
    • Cupric 8quinolinolate
    • Cupric 8quinolinoxide
    • Bis(8-quinolinato-N1'O8)copper (9CI)
    • Bis(8quinolinato)copper
    • Copper 8hydroxyquinolate
    • Copper 8hydroxyquinoline
    • Cupric 8hydroxyquinolate
    • Bis(8oxyquinoline)copper
    • 8Quinolinol, copper salt
    • Bis(8quinolinolato)copper
    • RefChem:168931
    • Copper 8hydroxyquinolinate
    • Bis(8-oxyquinoline) copper
    • Bis(8hydroxyquinolinato)copper
    • Bis(8quinolinatoN1'O8)copper
    • Copper bis(8hydroxyquinolinate)
    • 8Hydroxyquinoline copper complex
    • 8Quinolinol, copper(II) chelate
    • Bis(quinolin8olato)copper (IUPAC)
    • Copper, bis(8-quinolinolato)-(VAN)
    • Bis(8quinolinatoN1'O8)copper (9CI)
    • Copper, bis(8-quinolinolato)-(VAN) (8CI)
    • Copper, bis(8-quinolinolato-N1,O8)-(9CI)
    • Copper, bis(8quinolinolatoN(sup 1),O(sup 8))
    • Copper quinolate
    • Copper oxinate
    • Copper dioxinate
    • Copper oxyquinolate
    • Copper oxyquinoline
    • Copper quinolinolate
    • Copper(2+) oxinate
    • Copper hydroxyquinolate
    • copper quinolin-8-olate
    • Bis(8-hydroxyquinolinato)copper(II)
    • MFCD00067392
    • Copper-8-quinolinolate
    • 8-QUINOLINOL COPPER SALT
    • Copper(II) Bis(8-hydroxyquinolinate)
    • C18H12CuN2O2
    • copper(II) oxinate
    • copper;quinolin-8-olate
    • SCHEMBL166949
    • 8-Hydroxyquinoline copper(II)
    • SCHEMBL29350502
    • CHEBI:82028
    • AKOS015899053
    • FH40516
    • NCGC00164444-01
    • NCGC00164444-02
    • AS-10321
    • DB-040486
    • B1677
    • B3834
    • NS00078693
    • C18879
    • Q2629981
    • 10380-28-6

  • Applications

    Oxine-copper is a copper complex of 8-hydroxyquinoline, CAS 10380-28-6, used as a metal chelate and analytical reagent for trace copper determination; it is evaluated as a biocidal/antimicrobial additive in coatings, plastics and wood preservation; it may act as a stabilizer or processing additive in polymer systems; it also serves as an intermediate in the synthesis of coordination compounds and related specialty chemicals; and in research contexts it is considered a ligand for coordination chemistry and a precursor for functional materials in electronics or optoelectronics.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 65.88
    methanol 57.5
    isopropanol 47.95
    water 3.29
    ethyl acetate 134.33
    n-propanol 54.52
    acetone 205.65
    n-butanol 46.52
    acetonitrile 132.2
    DMF 344.63
    toluene 48.12
    isobutanol 43.77
    1,4-dioxane 606.1
    methyl acetate 156.3
    THF 344.3
    2-butanone 151.61
    n-pentanol 54.34
    sec-butanol 40.76
    n-hexane 12.79
    ethylene glycol 37.08
    NMP 298.68
    cyclohexane 10.74
    DMSO 458.62
    n-butyl acetate 134.27
    n-octanol 58.57
    chloroform 248.55
    n-propyl acetate 160.74
    acetic acid 128.02
    dichloromethane 343.26
    cyclohexanone 228.94
    propylene glycol 16.96
    isopropyl acetate 84.13
    DMAc 202.98
    2-ethoxyethanol 143.5
    isopentanol 48.64
    n-heptane 14.16
    ethyl formate 110.21
    1,2-dichloroethane 292.49
    n-hexanol 69.09
    2-methoxyethanol 177.39
    isobutyl acetate 99.65
    tetrachloromethane 39.97
    n-pentyl acetate 105.38
    transcutol 568.41
    n-heptanol 49.29
    ethylbenzene 47.47
    MIBK 85.68
    2-propoxyethanol 165.35
    tert-butanol 60.28
    MTBE 68.64
    2-butoxyethanol 124.87
    propionic acid 80.24
    o-xylene 42.4
    formic acid 54.56
    diethyl ether 105.53
    m-xylene 45.36
    p-xylene 69.04
    chlorobenzene 105.81
    dimethyl carbonate 83.4
    n-octane 9.32
    formamide 128.98
    cyclopentanone 303.49
    2-pentanone 118.13
    anisole 113.27
    cyclopentyl methyl ether 143.19
    gamma-butyrolactone 400.25
    1-methoxy-2-propanol 113.21
    pyridine 241.41
    3-pentanone 103.01
    furfural 342.49
    n-dodecane 8.65
    diethylene glycol 158.62
    diisopropyl ether 36.23
    tert-amyl alcohol 49.18
    acetylacetone 178.76
    n-hexadecane 10.05
    acetophenone 120.16
    methyl propionate 114.37
    isopentyl acetate 103.39
    trichloroethylene 444.69
    n-nonanol 52.79
    cyclohexanol 56.51
    benzyl alcohol 77.96
    2-ethylhexanol 52.04
    isooctanol 45.19
    dipropyl ether 74.47
    1,2-dichlorobenzene 99.87
    ethyl lactate 70.67
    propylene carbonate 182.04
    n-methylformamide 155.74
    2-pentanol 35.91
    n-pentane 8.08
    1-propoxy-2-propanol 104.23
    1-methoxy-2-propyl acetate 113.54
    2-(2-methoxypropoxy) propanol 111.47
    mesitylene 32.04
    ε-caprolactone 215.02
    p-cymene 32.84
    epichlorohydrin 514.17
    1,1,1-trichloroethane 152.17
    2-aminoethanol 45.48
    morpholine-4-carbaldehyde 408.15
    sulfolane 422.6
    2,2,4-trimethylpentane 6.14
    2-methyltetrahydrofuran 215.06
    n-hexyl acetate 141.38
    isooctane 6.04
    2-(2-butoxyethoxy)ethanol 176.16
    sec-butyl acetate 86.42
    tert-butyl acetate 86.98
    decalin 11.76
    glycerin 50.0
    diglyme 364.43
    acrylic acid 92.04
    isopropyl myristate 55.65
    n-butyric acid 89.59
    acetyl acetate 94.86
    di(2-ethylhexyl) phthalate 42.79
    ethyl propionate 118.92
    nitromethane 325.09
    1,2-diethoxyethane 186.22
    benzonitrile 129.4
    trioctyl phosphate 39.87
    1-bromopropane 102.79
    gamma-valerolactone 410.01
    n-decanol 42.98
    triethyl phosphate 51.63
    4-methyl-2-pentanol 31.85
    propionitrile 96.64
    vinylene carbonate 177.8
    1,1,2-trichlorotrifluoroethane 198.49
    DMS 146.68
    cumene 36.23
    2-octanol 40.89
    2-hexanone 140.49
    octyl acetate 70.98
    limonene 39.54
    1,2-dimethoxyethane 322.39
    ethyl orthosilicate 47.02
    tributyl phosphate 50.22
    diacetone alcohol 100.08
    N,N-dimethylaniline 74.75
    acrylonitrile 148.97
    aniline 69.3
    1,3-propanediol 72.31
    bromobenzene 103.09
    dibromomethane 200.62
    1,1,2,2-tetrachloroethane 270.07
    2-methyl-cyclohexyl acetate 70.92
    tetrabutyl urea 69.01
    diisobutyl methanol 35.91
    2-phenylethanol 84.66
    styrene 55.61
    dioctyl adipate 77.24
    dimethyl sulfate 160.03
    ethyl butyrate 91.22
    methyl lactate 63.37
    butyl lactate 76.37
    diethyl carbonate 68.3
    propanediol butyl ether 101.44
    triethyl orthoformate 61.61
    p-tert-butyltoluene 30.59
    methyl 4-tert-butylbenzoate 97.57
    morpholine 368.89
    tert-butylamine 37.61
    n-dodecanol 35.23
    dimethoxymethane 214.84
    ethylene carbonate 153.7
    cyrene 101.5
    2-ethoxyethyl acetate 159.11
    2-ethylhexyl acetate 86.95
    1,2,4-trichlorobenzene 119.56
    4-methylpyridine 183.19
    dibutyl ether 85.31
    2,6-dimethyl-4-heptanol 35.91
    DEF 160.14
    dimethyl isosorbide 190.69
    tetrachloroethylene 191.58
    eugenol 117.43
    triacetin 127.73
    span 80 83.78
    1,4-butanediol 46.53
    1,1-dichloroethane 162.13
    2-methyl-1-pentanol 50.16
    methyl formate 158.35
    2-methyl-1-butanol 41.09
    n-decane 13.16
    butyronitrile 87.19
    3,7-dimethyl-1-octanol 50.91
    1-chlorooctane 49.49
    1-chlorotetradecane 22.65
    n-nonane 12.56
    undecane 10.49
    tert-butylcyclohexane 11.89
    cyclooctane 5.56
    cyclopentanol 74.99
    tetrahydropyran 233.43
    tert-amyl methyl ether 53.93
    2,5,8-trioxanonane 222.63
    1-hexene 42.34
    2-isopropoxyethanol 107.19
    2,2,2-trifluoroethanol 78.26
    methyl butyrate 155.2

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction