Oleoyl Tyrosine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    147732-57-8

    Molecular formula
    C27H43NO4

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 36.19%
    Odorless 35.6%
    Fatty 32.82%
    Savory 32.66%
    Herbal 32.54%
    Meaty 30.92%
    Oily 28.27%
    Spicy 27.81%
    Citrus 26.23%
    Milky 24.71%

     

    Flavor
    Odorless 35.38%
    Bland 31.46%
    Mild 31.22%
    Herbal 31.01%
    Faint 25.12%
    Slightly waxy 20.57%
    Delicate 19.52%
    Woody 19.48%
    Bay oil 19.42%
    Cedarleaf 19.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.2

    pKa est.
    8.51 (weak base)

    Molecular weight
    445.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    678°C

    Flash point

    • 265.25 ˚C est.

  • Synonyms

    • OLEOYL TYROSINE
    • 131P1BQX1U
    • L-Tyrosine, N-(1-oxo-9-(Z)-octadecenyl)
    • L-Tyrosine, N-((9Z)-1-oxo-9-octadecenyl)-
    • L-Tyrosine, N-(1-oxo-9-octadecenyl)-, (Z)-
    • L-Tyrosine, N-((9Z)-1-oxo-9-octadecen-1-yl)-
    • RefChem:856534
    • OLEOYL TYROSINE [INCI]
    • N-oleoyl tyrosine
    • 147732-57-8
    • UNII-131P1BQX1U
    • N-(9Z-octadecenoyl)-tyrosine
    • (2S)-3-(4-hydroxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propanoic acid
    • N-Oleoyl-L-tyrosine
    • SCHEMBL424499
    • CHEMBL4228964
    • DTXSID20933200
    • CHEBI:165548
    • UOIBFJBJAWHQNM-JRUKXMRZSA-N
    • LMFA08020099
    • N-[(9Z)-Octadec-9-enoyl]-L-tyrosine
    • Q27251459
    • 147732-57-8

  • Applications

    Oleoyl Tyrosine (CAS 147732-57-8) is an amino acid–derived lipid conjugate with an oleoyl group, exhibiting amphiphilic properties and is considered as a surface-active additive. In cosmetics and personal care, it can act as a surfactant, emollient, and conditioning agent, helping improve skin feel and stabilize oil–water emulsions. In cleaning and household formulations, it may be used as a surfactant or dispersant to enhance detergency and particle dispersion. In industrial manufacturing, particularly in polymers and coatings/inks, it can serve as a surface-active additive or compatibilizer to improve wetting, dispersion, and surface adhesion. In pharmaceuticals and lipid-based delivery systems, it can be evaluated as an excipient or building block for lipid formulations and drug-delivery platforms, subject to local regulations and formulation limits. Overall, its use is case-by-case and dependent on regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 43.16
    methanol 77.56
    isopropanol 26.7
    water 0.21
    ethyl acetate 27.15
    n-propanol 32.19
    acetone 94.38
    n-butanol 23.66
    acetonitrile 10.7
    DMF 140.45
    toluene 10.29
    isobutanol 19.05
    1,4-dioxane 58.8
    methyl acetate 33.17
    THF 196.44
    2-butanone 69.73
    n-pentanol 24.94
    sec-butanol 28.01
    n-hexane 1.33
    ethylene glycol 4.52
    NMP 165.08
    cyclohexane 2.43
    DMSO 300.69
    n-butyl acetate 19.71
    n-octanol 13.7
    chloroform 39.09
    n-propyl acetate 25.49
    acetic acid 66.4
    dichloromethane 42.84
    cyclohexanone 103.0
    propylene glycol 13.85
    isopropyl acetate 24.95
    DMAc 356.89
    2-ethoxyethanol 66.14
    isopentanol 21.32
    n-heptane 1.07
    ethyl formate 20.17
    1,2-dichloroethane 37.73
    n-hexanol 13.68
    2-methoxyethanol 85.38
    isobutyl acetate 17.29
    tetrachloromethane 8.92
    n-pentyl acetate 31.35
    transcutol 210.27
    n-heptanol 15.4
    ethylbenzene 8.19
    MIBK 28.81
    2-propoxyethanol 47.08
    tert-butanol 33.41
    MTBE 32.18
    2-butoxyethanol 51.0
    propionic acid 31.11
    o-xylene 10.27
    formic acid 26.05
    diethyl ether 18.76
    m-xylene 7.34
    p-xylene 10.8
    chlorobenzene 11.31
    dimethyl carbonate 21.99
    n-octane 0.94
    formamide 49.36
    cyclopentanone 120.67
    2-pentanone 44.57
    anisole 21.53
    cyclopentyl methyl ether 41.14
    gamma-butyrolactone 95.47
    1-methoxy-2-propanol 69.63
    pyridine 41.33
    3-pentanone 36.91
    furfural 59.33
    n-dodecane 0.77
    diethylene glycol 25.96
    diisopropyl ether 5.94
    tert-amyl alcohol 39.91
    acetylacetone 62.38
    n-hexadecane 0.85
    acetophenone 31.39
    methyl propionate 32.99
    isopentyl acetate 22.87
    trichloroethylene 62.3
    n-nonanol 14.38
    cyclohexanol 28.45
    benzyl alcohol 23.42
    2-ethylhexanol 9.44
    isooctanol 13.58
    dipropyl ether 12.21
    1,2-dichlorobenzene 13.21
    ethyl lactate 20.38
    propylene carbonate 40.02
    n-methylformamide 47.42
    2-pentanol 15.18
    n-pentane 0.98
    1-propoxy-2-propanol 36.97
    1-methoxy-2-propyl acetate 36.75
    2-(2-methoxypropoxy) propanol 45.12
    mesitylene 4.69
    ε-caprolactone 76.5
    p-cymene 4.99
    epichlorohydrin 95.95
    1,1,1-trichloroethane 30.03
    2-aminoethanol 17.85
    morpholine-4-carbaldehyde 112.44
    sulfolane 181.02
    2,2,4-trimethylpentane 1.5
    2-methyltetrahydrofuran 77.1
    n-hexyl acetate 34.14
    isooctane 0.66
    2-(2-butoxyethoxy)ethanol 68.95
    sec-butyl acetate 20.44
    tert-butyl acetate 35.96
    decalin 1.89
    glycerin 21.49
    diglyme 123.87
    acrylic acid 24.65
    isopropyl myristate 11.92
    n-butyric acid 42.68
    acetyl acetate 19.96
    di(2-ethylhexyl) phthalate 14.73
    ethyl propionate 22.18
    nitromethane 88.7
    1,2-diethoxyethane 47.69
    benzonitrile 13.47
    trioctyl phosphate 11.11
    1-bromopropane 15.87
    gamma-valerolactone 161.36
    n-decanol 9.71
    triethyl phosphate 13.97
    4-methyl-2-pentanol 10.77
    propionitrile 11.32
    vinylene carbonate 29.35
    1,1,2-trichlorotrifluoroethane 83.51
    DMS 24.22
    cumene 6.61
    2-octanol 11.41
    2-hexanone 36.67
    octyl acetate 17.16
    limonene 7.72
    1,2-dimethoxyethane 94.52
    ethyl orthosilicate 14.99
    tributyl phosphate 13.54
    diacetone alcohol 59.78
    N,N-dimethylaniline 20.99
    acrylonitrile 13.08
    aniline 18.37
    1,3-propanediol 28.84
    bromobenzene 9.82
    dibromomethane 22.94
    1,1,2,2-tetrachloroethane 69.6
    2-methyl-cyclohexyl acetate 21.79
    tetrabutyl urea 23.62
    diisobutyl methanol 6.79
    2-phenylethanol 17.06
    styrene 8.3
    dioctyl adipate 22.29
    dimethyl sulfate 50.54
    ethyl butyrate 17.91
    methyl lactate 27.89
    butyl lactate 34.48
    diethyl carbonate 11.37
    propanediol butyl ether 43.72
    triethyl orthoformate 18.85
    p-tert-butyltoluene 4.82
    methyl 4-tert-butylbenzoate 40.36
    morpholine 93.1
    tert-butylamine 13.92
    n-dodecanol 6.71
    dimethoxymethane 81.29
    ethylene carbonate 27.33
    cyrene 48.98
    2-ethoxyethyl acetate 48.95
    2-ethylhexyl acetate 17.1
    1,2,4-trichlorobenzene 20.15
    4-methylpyridine 34.65
    dibutyl ether 16.4
    2,6-dimethyl-4-heptanol 6.79
    DEF 60.02
    dimethyl isosorbide 71.91
    tetrachloroethylene 43.49
    eugenol 36.62
    triacetin 44.61
    span 80 36.89
    1,4-butanediol 14.31
    1,1-dichloroethane 27.44
    2-methyl-1-pentanol 24.67
    methyl formate 30.69
    2-methyl-1-butanol 23.34
    n-decane 1.51
    butyronitrile 12.45
    3,7-dimethyl-1-octanol 12.04
    1-chlorooctane 7.42
    1-chlorotetradecane 2.65
    n-nonane 1.29
    undecane 1.03
    tert-butylcyclohexane 1.61
    cyclooctane 0.8
    cyclopentanol 35.79
    tetrahydropyran 61.86
    tert-amyl methyl ether 29.73
    2,5,8-trioxanonane 79.43
    1-hexene 5.96
    2-isopropoxyethanol 42.79
    2,2,2-trifluoroethanol 24.28
    methyl butyrate 34.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction