Oleamidopropyl Betaine

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  • Identifiers

    CAS number
    25054-76-6

    Molecular formula
    C25H48N2O3

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)[O-]

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 36.64%
    Meaty 36.39%
    Fatty 35.09%
    Savory 33.71%
    Odorless 28.55%
    Animal 26.62%
    Oily 26.21%
    Woody 26.18%
    Citrus 25.45%
    Fishy 25.07%

     

    Flavor
    Bland 34.56%
    Mild 26.94%
    Odorless 26.75%
    Faint 25.03%
    Herbal 24.84%
    Slightly waxy 20.81%
    Delicate 20.33%
    Bay oil 19.52%
    Diterpene 19.05%
    Low 18.82%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    7.7

    pKa est.
    5.26 (weak acid)

    Molecular weight
    424.7 g/mol

    Flash point

    • -33.17 ˚C est.

  • Synonyms

    • Oleamidopropyl betaine
    • UK7B5M6P8Q
    • Oleamidopropyl dimethyl glycine
    • (Z)-(Carboxymethyl)dimethyl-3-[(1-oxo-9-octadecenyl)amino]propylammonium hydroxide
    • (Z)-(Carboxymethyl)dimethyl-3-((1-oxo-9-octadecenyl)amino)propylammonium hydroxide
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxo-9-octadecenyl)amino)-, hydroxide, inner salt, (Z)-
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxo-9-octadecenyl)amino]-, hydroxide, inner salt, (Z)-
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[[(9Z)-1-oxo-9-octadecenyl]amino]-, inner salt
    • RefChem:856479
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-(((9Z)-1-oxo-9-octadecenyl)amino)-, inner salt
    • OLEAMIDOPROPYL BETAINE [INCI]
    • N-(Carboxymethyl)-N,N-Dimethyl-3-((1-Oxooctadecenyl)Amino)-1-Prop-
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-(9Z)-1-oxo-9-octadecenylamino-, inner salt
    • 25054-76-6
    • N-Oleoylamidopropyl-N,N-dimethylbetaine
    • 2-(Dimethyl(3-oleamidopropyl)ammonio)acetate
    • UNII-UK7B5M6P8Q
    • EINECS 246-584-2
    • 2-[dimethyl-[3-[[(Z)-octadec-9-enoyl]amino]propyl]azaniumyl]acetate
    • SCHEMBL16339377
    • DTXSID20893471
    • ZKWJQNCOTNUNMF-QXMHVHEDSA-N
    • N-(Carboxymethyl)-N,N-dimethyl-3-((1-oxooctadecenyl)amino)-1-prop- anaminium hydroxide, inner salt
    • A937119
    • Q27291115
    • (Dimethyl{3-[(9Z)-octadec-9-enamido]propyl}azaniumyl)acetate
    • Amidopropylalkyl carboxymethyl dimethyl ammonium compound C18 unsatd (apAcMDMAC C18 unsatd)
    • 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL- 3-((1-OXO-9-OCTADECENYL)AMINO)-, HYDROXIDE, INNER SALT, (Z)-
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxooctadecenyl)amino)-, hydroxide, inner salt
    • 25054-76-6

  • Applications

    Oleamidopropyl Betaine (CAS 25054-76-6) is a mild zwitterionic surfactant used as a co-surfactant, foam booster and gentle emulsifier in personal care products such as shampoos, body washes and facial cleansers; it also serves as a conditioning agent in hair care formulations and helps stabilize foams. In household and industrial cleaners it acts as a surfactant and wetting agent to improve cleaning performance; in paints, coatings and inks it can serve as an emulsifier and rheology modifier to stabilize emulsions and improve formulation compatibility; in polymer and plastics processing it can be used as a processing aid or surface-active additive; and it is sometimes formulated as an ingredient or adjuvant in pharmaceutical topical products to aid dispersion and stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 35.28
    methanol 77.85
    isopropanol 15.38
    water 1.98
    ethyl acetate 15.97
    n-propanol 28.4
    acetone 33.76
    n-butanol 19.89
    acetonitrile 8.57
    DMF 78.16
    toluene 11.17
    isobutanol 18.67
    1,4-dioxane 30.82
    methyl acetate 18.2
    THF 68.0
    2-butanone 30.03
    n-pentanol 17.74
    sec-butanol 18.56
    n-hexane 1.7
    ethylene glycol 10.58
    NMP 189.55
    cyclohexane 4.2
    DMSO 102.22
    n-butyl acetate 15.31
    n-octanol 12.46
    chloroform 78.4
    n-propyl acetate 18.71
    acetic acid 103.23
    dichloromethane 70.8
    cyclohexanone 76.22
    propylene glycol 19.37
    isopropyl acetate 12.83
    DMAc 147.09
    2-ethoxyethanol 49.56
    isopentanol 16.01
    n-heptane 1.14
    ethyl formate 21.9
    1,2-dichloroethane 44.09
    n-hexanol 13.38
    2-methoxyethanol 62.19
    isobutyl acetate 13.39
    tetrachloromethane 17.79
    n-pentyl acetate 24.96
    transcutol 138.63
    n-heptanol 15.13
    ethylbenzene 7.29
    MIBK 17.01
    2-propoxyethanol 43.02
    tert-butanol 17.23
    MTBE 10.34
    2-butoxyethanol 47.37
    propionic acid 41.86
    o-xylene 12.3
    formic acid 75.05
    diethyl ether 8.47
    m-xylene 9.15
    p-xylene 8.95
    chlorobenzene 16.25
    dimethyl carbonate 14.71
    n-octane 0.78
    formamide 79.55
    cyclopentanone 81.33
    2-pentanone 23.07
    anisole 12.76
    cyclopentyl methyl ether 31.78
    gamma-butyrolactone 90.78
    1-methoxy-2-propanol 42.95
    pyridine 36.72
    3-pentanone 21.09
    furfural 79.74
    n-dodecane 0.51
    diethylene glycol 34.42
    diisopropyl ether 3.4
    tert-amyl alcohol 20.82
    acetylacetone 31.19
    n-hexadecane 0.58
    acetophenone 25.16
    methyl propionate 21.74
    isopentyl acetate 17.06
    trichloroethylene 92.82
    n-nonanol 12.19
    cyclohexanol 30.78
    benzyl alcohol 21.82
    2-ethylhexanol 10.19
    isooctanol 13.24
    dipropyl ether 8.1
    1,2-dichlorobenzene 19.67
    ethyl lactate 20.0
    propylene carbonate 46.73
    n-methylformamide 49.4
    2-pentanol 11.23
    n-pentane 1.5
    1-propoxy-2-propanol 30.34
    1-methoxy-2-propyl acetate 27.23
    2-(2-methoxypropoxy) propanol 39.64
    mesitylene 5.97
    ε-caprolactone 70.22
    p-cymene 5.93
    epichlorohydrin 77.57
    1,1,1-trichloroethane 33.26
    2-aminoethanol 29.15
    morpholine-4-carbaldehyde 90.51
    sulfolane 182.98
    2,2,4-trimethylpentane 1.77
    2-methyltetrahydrofuran 42.16
    n-hexyl acetate 25.84
    isooctane 0.71
    2-(2-butoxyethoxy)ethanol 54.81
    sec-butyl acetate 13.4
    tert-butyl acetate 18.22
    decalin 2.26
    glycerin 39.74
    diglyme 93.77
    acrylic acid 43.76
    isopropyl myristate 7.65
    n-butyric acid 46.56
    acetyl acetate 16.02
    di(2-ethylhexyl) phthalate 16.39
    ethyl propionate 14.97
    nitromethane 77.51
    1,2-diethoxyethane 20.52
    benzonitrile 16.04
    trioctyl phosphate 10.97
    1-bromopropane 16.96
    gamma-valerolactone 123.62
    n-decanol 7.58
    triethyl phosphate 14.18
    4-methyl-2-pentanol 8.16
    propionitrile 9.49
    vinylene carbonate 43.19
    1,1,2-trichlorotrifluoroethane 126.48
    DMS 21.38
    cumene 6.39
    2-octanol 9.23
    2-hexanone 20.64
    octyl acetate 11.99
    limonene 9.06
    1,2-dimethoxyethane 44.29
    ethyl orthosilicate 13.89
    tributyl phosphate 12.81
    diacetone alcohol 35.81
    N,N-dimethylaniline 13.5
    acrylonitrile 14.11
    aniline 20.88
    1,3-propanediol 31.83
    bromobenzene 13.48
    dibromomethane 41.37
    1,1,2,2-tetrachloroethane 94.11
    2-methyl-cyclohexyl acetate 21.61
    tetrabutyl urea 18.69
    diisobutyl methanol 5.54
    2-phenylethanol 18.49
    styrene 7.21
    dioctyl adipate 18.58
    dimethyl sulfate 41.36
    ethyl butyrate 14.57
    methyl lactate 28.92
    butyl lactate 32.51
    diethyl carbonate 10.65
    propanediol butyl ether 44.4
    triethyl orthoformate 16.08
    p-tert-butyltoluene 5.57
    methyl 4-tert-butylbenzoate 37.61
    morpholine 53.94
    tert-butylamine 8.76
    n-dodecanol 4.86
    dimethoxymethane 34.28
    ethylene carbonate 34.0
    cyrene 55.38
    2-ethoxyethyl acetate 35.82
    2-ethylhexyl acetate 14.73
    1,2,4-trichlorobenzene 27.37
    4-methylpyridine 26.65
    dibutyl ether 8.26
    2,6-dimethyl-4-heptanol 5.54
    DEF 38.17
    dimethyl isosorbide 59.81
    tetrachloroethylene 76.08
    eugenol 35.83
    triacetin 42.38
    span 80 37.86
    1,4-butanediol 16.81
    1,1-dichloroethane 26.98
    2-methyl-1-pentanol 17.41
    methyl formate 33.56
    2-methyl-1-butanol 20.2
    n-decane 1.1
    butyronitrile 10.41
    3,7-dimethyl-1-octanol 10.31
    1-chlorooctane 6.17
    1-chlorotetradecane 1.85
    n-nonane 0.98
    undecane 0.71
    tert-butylcyclohexane 1.69
    cyclooctane 1.41
    cyclopentanol 33.71
    tetrahydropyran 33.4
    tert-amyl methyl ether 13.42
    2,5,8-trioxanonane 60.51
    1-hexene 5.3
    2-isopropoxyethanol 30.52
    2,2,2-trifluoroethanol 54.75
    methyl butyrate 22.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction