Oleamide

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  • Identifiers

    CAS number
    301-02-0

    Molecular formula
    C18H35NO

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)N

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fatty 61.12%
    Waxy 55.75%
    Meaty 38.18%
    Oily 37.79%
    Savory 30.81%
    Citrus 27.35%
    Fishy 25.91%
    Dairy 24.94%
    Milky 24.75%
    Fresh 24.03%

     

    Flavor
    Fatty 33.11%
    Faint 29.45%
    Waxy 26.21%
    Bland 23.04%
    Slightly waxy 22.82%
    Fat 21.59%
    Mild 21.5%
    Delicate 21.34%
    Bay oil 20.75%
    Diterpene 19.94%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.6

    pKa est.
    6.98 (neutral)

    Molecular weight
    281.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    356°C

    Melting point expt.

    • 76 °C
    • 102 - 104 °C

    Flash point

    • 184.69 ˚C est.

    Solubility expt.

    • INSOL IN WATER; SOL IN ETHER, HOT ALCOHOL

  • Synonyms

    • Oleamide
    • 301-02-0
    • Oleic acid amide
    • Oleylamide
    • Oleyl amide
    • (Z)-octadec-9-enamide
    • Adogen 73
    • Crodamide O
    • Crodamide OR
    • Slip-eze
    • Armoslip CP
    • (Z)-9-OCTADECENAMIDE
    • 9Z-octadecenamide
    • Armid O
    • 9-Octadecenamide, (9Z)-
    • 9,10-octadecenamide
    • 7L25QK8BWO
    • NSC-26987
    • CHEBI:116314
    • RefChem:856476
    • 206-103-9
    • (9Z)-octadec-9-enamide
    • 9-Octadecenamide, (Z)-
    • cis-9,10-Octadecenoamide
    • (9Z)-9-Octadecenamide
    • ELAIDOYLAMIDE
    • Unislip 1759
    • 9,10-octadecenoamide
    • Kemamide O
    • Petrac Slip-Eze
    • Amide O
    • cis-9-Octadecenamide
    • 14C-labeled oleamide
    • Diamide O 200
    • (9E)-OCTADEC-9-ENAMIDE
    • Tocris-0878
    • 9-Octadecenamide, cis-
    • MFCD00053638
    • CHEMBL15927
    • DTXSID6027137
    • ELD
    • octadec-9-enamide
    • Oleyramide
    • HSDB 5560
    • 9-Octadecenoic acid, amide (cis)
    • SR-01000597434
    • EINECS 206-103-9
    • NSC 26987
    • UNII-7L25QK8BWO
    • trans-9,10-octadecenoamide
    • Aliphatic amide
    • AI3-36742
    • CCRIS 9471
    • Octadecene amide
    • 9(z)-octadecenamide
    • (9Z)-octadecenamide
    • Plastic additive 12
    • Diamid O 200
    • Diamit O 200
    • Oleamide, >=99%
    • (cis)-9-Octadecenoate
    • A1EJM
    • cis-9,10-Octadecanamide
    • Plastic additive 20 CRS
    • (cis)-9-Octadecenoic acid
    • OLEYL AMIDE [HSDB]
    • (9Z)-9-Octadecenamide #
    • SCHEMBL36321
    • BSPBio_001489
    • GTPL284
    • Oleamide, analytical standard
    • BML2-C10
    • DTXCID607137
    • orb1707879
    • orb3025242
    • SCHEMBL2774552
    • BDBM23028
    • (cis)-9-Octadecenoic acid amide
    • (Z)-Octadec-9-enoic acid amide
    • MSK2981
    • HMS1361K11
    • HMS1791K11
    • HMS1989K11
    • HMS3402K11
    • HMS3411B12
    • HMS3649L11
    • HMS3675B12
    • HY-N2327
    • NSC26987
    • OLEAMIDE (OLEIC ACID AMIDE)
    • Tox21_200444
    • LMFA08010004
    • MSK2981-100M
    • AKOS016010402
    • CCG-208731
    • EBC-616182
    • FO26543
    • PLASTIC ADDITIVE 12 [USP-RS]
    • IDI1_033959
    • NCGC00024839-01
    • NCGC00024839-04
    • NCGC00024839-05
    • NCGC00024839-06
    • NCGC00024839-07
    • NCGC00024839-08
    • NCGC00257998-01
    • AS-12260
    • CAS-301-02-0
    • MSK2981-1000
    • Oleamide Solution in Methanol, 100ug/mL
    • Oleamide Solution in Methanol, 1000?g/mL
    • CS-0021046
    • NS00006123
    • O0107
    • Q4370
    • C19670
    • A820197
    • SR-01000597434-1
    • SR-01000597434-2
    • BRD-K06644925-001-03-0
    • Plastic additive 20, European Pharmacopoeia (EP) Reference Standard
    • Plastic additive 12, United States Pharmacopeia (USP) Reference Standard
    • 301-02-0

  • Applications

    Oleamide (CAS 301-02-0) is commonly used as a slip/anti-blocking agent and processing aid in polymers and plastics, improving flow, reducing tack, and facilitating film release in polyolefins and related materials. It also serves as a surface-modifying additive in coatings and inks, helping prevent sticking and improving lubrication at interfaces. In adhesives and sealants, oleamide can act as a processing lubricant and release agent to enhance spreadability and curing behavior. In cosmetics and personal care, it is employed as an emollient and conditioning agent, imparting slip and a smooth texture to formulations such as creams and lip products. Additional roles include use as a surfactant or specialty lubricant in cleaning formulations and household products, where it aids wetting and dispersion. In some formulations, it may be used as an intermediate or starting material for further chemical synthesis. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 72.58
    methanol 65.21
    isopropanol 73.31
    water 0.01
    ethyl acetate 105.71
    n-propanol 70.15
    acetone 104.49
    n-butanol 83.23
    acetonitrile 23.2
    DMF 141.06
    toluene 43.16
    isobutanol 60.71
    1,4-dioxane 126.26
    methyl acetate 56.56
    THF 448.13
    2-butanone 113.21
    n-pentanol 70.67
    sec-butanol 67.55
    n-hexane 22.02
    ethylene glycol 3.01
    NMP 237.52
    cyclohexane 46.98
    DMSO 253.75
    n-butyl acetate 156.65
    n-octanol 44.49
    chloroform 226.04
    n-propyl acetate 150.03
    acetic acid 44.98
    dichloromethane 196.76
    cyclohexanone 286.19
    propylene glycol 14.58
    isopropyl acetate 117.64
    DMAc 238.48
    2-ethoxyethanol 121.47
    isopentanol 95.38
    n-heptane 18.45
    ethyl formate 46.6
    1,2-dichloroethane 160.34
    n-hexanol 71.74
    2-methoxyethanol 123.93
    isobutyl acetate 115.6
    tetrachloromethane 48.39
    n-pentyl acetate 150.88
    transcutol 604.05
    n-heptanol 48.59
    ethylbenzene 38.38
    MIBK 140.1
    2-propoxyethanol 145.35
    tert-butanol 111.21
    MTBE 137.98
    2-butoxyethanol 120.17
    propionic acid 45.25
    o-xylene 41.56
    formic acid 8.84
    diethyl ether 109.21
    m-xylene 40.2
    p-xylene 49.12
    chlorobenzene 68.06
    dimethyl carbonate 23.71
    n-octane 7.17
    formamide 14.43
    cyclopentanone 290.01
    2-pentanone 144.02
    anisole 83.42
    cyclopentyl methyl ether 202.45
    gamma-butyrolactone 227.29
    1-methoxy-2-propanol 144.68
    pyridine 113.93
    3-pentanone 96.85
    furfural 164.7
    n-dodecane 4.49
    diethylene glycol 54.2
    diisopropyl ether 49.82
    tert-amyl alcohol 99.75
    acetylacetone 162.69
    n-hexadecane 5.41
    acetophenone 105.56
    methyl propionate 75.33
    isopentyl acetate 166.79
    trichloroethylene 244.65
    n-nonanol 47.04
    cyclohexanol 104.27
    benzyl alcohol 57.19
    2-ethylhexanol 67.45
    isooctanol 52.71
    dipropyl ether 136.54
    1,2-dichlorobenzene 80.82
    ethyl lactate 58.22
    propylene carbonate 134.54
    n-methylformamide 39.62
    2-pentanol 61.95
    n-pentane 12.6
    1-propoxy-2-propanol 152.46
    1-methoxy-2-propyl acetate 167.74
    2-(2-methoxypropoxy) propanol 116.63
    mesitylene 33.82
    ε-caprolactone 223.9
    p-cymene 35.76
    epichlorohydrin 247.53
    1,1,1-trichloroethane 159.97
    2-aminoethanol 18.22
    morpholine-4-carbaldehyde 187.28
    sulfolane 387.48
    2,2,4-trimethylpentane 12.22
    2-methyltetrahydrofuran 264.39
    n-hexyl acetate 152.06
    isooctane 8.73
    2-(2-butoxyethoxy)ethanol 169.18
    sec-butyl acetate 117.41
    tert-butyl acetate 166.59
    decalin 21.66
    glycerin 23.66
    diglyme 338.12
    acrylic acid 25.61
    isopropyl myristate 56.76
    n-butyric acid 125.9
    acetyl acetate 64.62
    di(2-ethylhexyl) phthalate 50.7
    ethyl propionate 109.14
    nitromethane 80.76
    1,2-diethoxyethane 217.17
    benzonitrile 64.59
    trioctyl phosphate 38.22
    1-bromopropane 112.81
    gamma-valerolactone 337.61
    n-decanol 31.47
    triethyl phosphate 73.6
    4-methyl-2-pentanol 50.92
    propionitrile 39.26
    vinylene carbonate 86.88
    1,1,2-trichlorotrifluoroethane 180.14
    DMS 69.11
    cumene 32.34
    2-octanol 37.39
    2-hexanone 154.03
    octyl acetate 65.27
    limonene 63.32
    1,2-dimethoxyethane 243.59
    ethyl orthosilicate 79.45
    tributyl phosphate 51.63
    diacetone alcohol 165.96
    N,N-dimethylaniline 68.36
    acrylonitrile 33.11
    aniline 50.63
    1,3-propanediol 46.63
    bromobenzene 77.13
    dibromomethane 143.71
    1,1,2,2-tetrachloroethane 275.11
    2-methyl-cyclohexyl acetate 133.7
    tetrabutyl urea 73.49
    diisobutyl methanol 49.93
    2-phenylethanol 65.87
    styrene 43.47
    dioctyl adipate 90.29
    dimethyl sulfate 60.08
    ethyl butyrate 143.09
    methyl lactate 43.97
    butyl lactate 110.93
    diethyl carbonate 73.2
    propanediol butyl ether 98.04
    triethyl orthoformate 121.18
    p-tert-butyltoluene 35.69
    methyl 4-tert-butylbenzoate 119.96
    morpholine 208.54
    tert-butylamine 74.7
    n-dodecanol 22.51
    dimethoxymethane 116.53
    ethylene carbonate 83.86
    cyrene 113.77
    2-ethoxyethyl acetate 160.41
    2-ethylhexyl acetate 130.64
    1,2,4-trichlorobenzene 101.36
    4-methylpyridine 118.69
    dibutyl ether 117.37
    2,6-dimethyl-4-heptanol 49.93
    DEF 154.79
    dimethyl isosorbide 237.12
    tetrachloroethylene 168.64
    eugenol 95.55
    triacetin 158.7
    span 80 109.44
    1,4-butanediol 18.03
    1,1-dichloroethane 131.38
    2-methyl-1-pentanol 76.99
    methyl formate 24.28
    2-methyl-1-butanol 77.56
    n-decane 10.04
    butyronitrile 68.56
    3,7-dimethyl-1-octanol 58.18
    1-chlorooctane 44.4
    1-chlorotetradecane 14.71
    n-nonane 9.57
    undecane 6.24
    tert-butylcyclohexane 17.99
    cyclooctane 12.48
    cyclopentanol 102.29
    tetrahydropyran 240.43
    tert-amyl methyl ether 113.71
    2,5,8-trioxanonane 205.64
    1-hexene 58.46
    2-isopropoxyethanol 108.39
    2,2,2-trifluoroethanol 15.35
    methyl butyrate 161.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction