Octenidine Hydrochloride

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  • Identifiers

    CAS number
    70775-75-6

    Molecular formula
    C36H64Cl2N4

    SMILES
    CCCCCCCCN=C1C=CN(C=C1)CCCCCCCCCCN2C=CC(=NCCCCCCCC)C=C2.Cl.Cl

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Fatty 43.41%
    Waxy 40.2%
    Meaty 38.96%
    Fishy 35.05%
    Roasted 30.8%
    Animal 30.69%
    Oily 30.24%
    Fresh 30.12%
    Savory 26.87%
    Burnt 26.66%

     

    Flavor
    Herbal 26.43%
    Waxy 24.02%
    Mild 22.85%
    Bland 22.68%
    Fatty 21.72%
    Delicate 20.8%
    Slightly waxy 20.75%
    Diterpene 20.04%
    Low 19.93%
    Carrot 19.73%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.79 (weak base)

    Molecular weight
    623.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    738°C

    Flash point

    • 306.78 ˚C est.

  • Synonyms

    • 70775-75-6
    • OCTENIDINE HYDROCHLORIDE
    • Octenidine HCl
    • Sensidin do
    • Win 41464-2
    • U84956NU4B
    • LAS189962
    • LAS-189962
    • WIN-41464-2
    • DTXSID90221025
    • octeniderm
    • Octenidol
    • RefChem:856047
    • DTXCID90143516
    • N,N'-(1,10-decanediyldi-1-(4H)-pyridinyl-4-ylidene)bis-(1-octamine) dihydrochloride
    • 274-861-8
    • Octenidine dihydrochloride
    • Octenidine (dihydrochloride)
    • 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochloride
    • 1-Octanamine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2)
    • MFCD01938808
    • Octenidine hydrochloride [USAN]
    • N-octyl-1-[10-(4-octyliminopyridin-1-yl)decyl]pyridin-4-imine;dihydrochloride
    • N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride
    • Octenidine hydrochloride (USAN)
    • N,N'-(Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride
    • 1,1'-Decamethylenebis(1,4-dihydro-4-(octylimino)pyridine) dihydrochloride
    • 1-Octanamine, N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, dihydrochloride
    • N,N'-(1,1'-(Decane-1,10-diyl)bis(pyridin-1(1H)-yl-4(1H)-ylidene))bis(octan-1-amine) dihydrochloride
    • CHEMBL36342
    • SCHEMBL126065
    • UNII-U84956NU4B
    • C36H64Cl2N4
    • HY-B2170A
    • Win-414642
    • SMGTYJPMKXNQFY-UHFFFAOYSA-N
    • HMS5084A11
    • EINECS 274-861-8
    • s5012
    • CCG-270262
    • CS-6224
    • FO46353
    • OCTENIDINE DIHYDROCHLORIDE [MI]
    • OCTENIDINE HYDROCHLORIDE [MART.]
    • OCTENIDINE HYDROCHLORIDE [WHO-DD]
    • O0388
    • D05222
    • D86682
    • Q1409243
    • N,N'-[Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene]bis(octylammonium) di chloride
    • N-octyl-1-[10-(4-octylimino-1-pyridyl)decyl]pyridin-4-imine;dihydrochloride
    • 70775-75-6

  • Applications

    Chemical name Octenidine Hydrochloride (CAS 70775-75-6) is used as a cationic antiseptic in topical formulations for skin and wound care (in solution or cream forms); in mucosal or oral antiseptic products in certain markets; in surface-disinfection formulations for healthcare and industrial cleaning; in antimicrobial coatings for medical devices and polymeric materials; and as an active component in consumer household cleaning products where antimicrobial action is desired.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 24.1
    methanol 19.57
    isopropanol 21.47
    water 0.39
    ethyl acetate 322.11
    n-propanol 38.55
    acetone 229.77
    n-butanol 46.57
    acetonitrile 67.67
    DMF 196.4
    toluene 381.08
    isobutanol 39.44
    1,4-dioxane 342.83
    methyl acetate 227.66
    THF 855.95
    2-butanone 303.47
    n-pentanol 41.52
    sec-butanol 44.07
    n-hexane 39.0
    ethylene glycol 4.3
    NMP 881.29
    cyclohexane 172.19
    DMSO 304.05
    n-butyl acetate 236.25
    n-octanol 35.17
    chloroform 1986.24
    n-propyl acetate 212.44
    acetic acid 135.94
    dichloromethane 2461.21
    cyclohexanone 893.24
    propylene glycol 8.43
    isopropyl acetate 233.81
    DMAc 578.5
    2-ethoxyethanol 82.47
    isopentanol 54.39
    n-heptane 39.97
    ethyl formate 145.62
    1,2-dichloroethane 1219.94
    n-hexanol 37.67
    2-methoxyethanol 88.23
    isobutyl acetate 146.92
    tetrachloromethane 514.9
    n-pentyl acetate 258.55
    transcutol 344.22
    n-heptanol 42.53
    ethylbenzene 114.16
    MIBK 182.93
    2-propoxyethanol 96.27
    tert-butanol 33.55
    MTBE 129.5
    2-butoxyethanol 106.48
    propionic acid 115.18
    o-xylene 224.99
    formic acid 34.63
    diethyl ether 154.23
    m-xylene 202.24
    p-xylene 172.4
    chlorobenzene 619.73
    dimethyl carbonate 157.01
    n-octane 15.99
    formamide 59.04
    cyclopentanone 931.8
    2-pentanone 279.15
    anisole 167.27
    cyclopentyl methyl ether 557.85
    gamma-butyrolactone 942.14
    1-methoxy-2-propanol 82.93
    pyridine 562.78
    3-pentanone 338.27
    furfural 621.12
    n-dodecane 8.08
    diethylene glycol 39.64
    diisopropyl ether 72.95
    tert-amyl alcohol 65.76
    acetylacetone 434.28
    n-hexadecane 9.79
    acetophenone 239.42
    methyl propionate 281.44
    isopentyl acetate 218.45
    trichloroethylene 2113.54
    n-nonanol 40.64
    cyclohexanol 174.09
    benzyl alcohol 111.43
    2-ethylhexanol 58.51
    isooctanol 45.33
    dipropyl ether 168.67
    1,2-dichlorobenzene 570.27
    ethyl lactate 74.09
    propylene carbonate 528.98
    n-methylformamide 93.65
    2-pentanol 45.04
    n-pentane 32.93
    1-propoxy-2-propanol 100.58
    1-methoxy-2-propyl acetate 255.11
    2-(2-methoxypropoxy) propanol 97.53
    mesitylene 124.54
    ε-caprolactone 683.06
    p-cymene 89.98
    epichlorohydrin 1103.24
    1,1,1-trichloroethane 1341.84
    2-aminoethanol 12.5
    morpholine-4-carbaldehyde 416.2
    sulfolane 1296.96
    2,2,4-trimethylpentane 28.73
    2-methyltetrahydrofuran 636.14
    n-hexyl acetate 189.57
    isooctane 12.16
    2-(2-butoxyethoxy)ethanol 119.84
    sec-butyl acetate 173.5
    tert-butyl acetate 264.77
    decalin 49.48
    glycerin 18.32
    diglyme 367.69
    acrylic acid 103.63
    isopropyl myristate 69.8
    n-butyric acid 213.82
    acetyl acetate 307.1
    di(2-ethylhexyl) phthalate 75.87
    ethyl propionate 207.09
    nitromethane 314.59
    1,2-diethoxyethane 243.86
    benzonitrile 178.82
    trioctyl phosphate 48.23
    1-bromopropane 547.76
    gamma-valerolactone 935.24
    n-decanol 27.31
    triethyl phosphate 152.6
    4-methyl-2-pentanol 33.66
    propionitrile 86.11
    vinylene carbonate 423.86
    1,1,2-trichlorotrifluoroethane 624.74
    DMS 203.58
    cumene 72.8
    2-octanol 33.77
    2-hexanone 198.33
    octyl acetate 90.06
    limonene 158.67
    1,2-dimethoxyethane 223.41
    ethyl orthosilicate 151.95
    tributyl phosphate 70.09
    diacetone alcohol 169.43
    N,N-dimethylaniline 126.15
    acrylonitrile 97.64
    aniline 269.38
    1,3-propanediol 27.4
    bromobenzene 803.81
    dibromomethane 1330.29
    1,1,2,2-tetrachloroethane 1745.18
    2-methyl-cyclohexyl acetate 210.09
    tetrabutyl urea 93.35
    diisobutyl methanol 42.25
    2-phenylethanol 92.21
    styrene 157.17
    dioctyl adipate 124.22
    dimethyl sulfate 367.6
    ethyl butyrate 241.56
    methyl lactate 91.11
    butyl lactate 128.08
    diethyl carbonate 150.25
    propanediol butyl ether 51.64
    triethyl orthoformate 211.45
    p-tert-butyltoluene 82.15
    methyl 4-tert-butylbenzoate 205.25
    morpholine 351.57
    tert-butylamine 28.22
    n-dodecanol 20.65
    dimethoxymethane 206.22
    ethylene carbonate 384.13
    cyrene 163.39
    2-ethoxyethyl acetate 354.17
    2-ethylhexyl acetate 222.25
    1,2,4-trichlorobenzene 730.12
    4-methylpyridine 495.09
    dibutyl ether 126.32
    2,6-dimethyl-4-heptanol 42.25
    DEF 343.68
    dimethyl isosorbide 327.85
    tetrachloroethylene 1227.44
    eugenol 133.04
    triacetin 268.75
    span 80 94.65
    1,4-butanediol 14.53
    1,1-dichloroethane 863.81
    2-methyl-1-pentanol 55.18
    methyl formate 109.61
    2-methyl-1-butanol 62.57
    n-decane 17.97
    butyronitrile 98.81
    3,7-dimethyl-1-octanol 43.16
    1-chlorooctane 79.26
    1-chlorotetradecane 25.92
    n-nonane 17.41
    undecane 11.26
    tert-butylcyclohexane 31.52
    cyclooctane 56.78
    cyclopentanol 159.24
    tetrahydropyran 503.02
    tert-amyl methyl ether 171.6
    2,5,8-trioxanonane 194.51
    1-hexene 77.86
    2-isopropoxyethanol 73.44
    2,2,2-trifluoroethanol 110.81
    methyl butyrate 264.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction