O-Anisidine

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    90-04-0

    Molecular formula
    C7H9NO

    SMILES
    COC1=CC=CC=C1N

    Safety labels

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

    Retention indicies (RI)

    • Carbowax: 1971.0

  • Odor profile

    Sweet 70.14%
    Phenolic 60.5%
    Vanilla 47.7%
    Smoky 46.52%
    Spicy 38.91%
    Medicinal 37.63%
    Burnt 36.87%
    Earthy 33.4%
    Powdery 33.21%
    Musty 32.49%

    Scent© AI

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    123.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Melting point expt.

    • 41 °F (NTP, 1992)
    • 6.2 °C
    • 5 °C
    • 41 °F

    Boiling point

    • 437 °F at 760 mmHg (NTP, 1992)
    • 224 °C
    • 224-225 °C
    • 437 °F

    Flash point est.
    94.17 ˚C

    Flash point expt.

    • 210 °F (NTP, 1992)
    • 118 °C
    • 118 °C, 244 °F (open cup)
    • 107 °C c.c.
    • (oc) 244 °F

    Solubility expt.

    • less than 0.1 mg/mL at 66 °F (NTP, 1992)
    • Miscible with ethanol, benzene, diethyl ether and acetone
    • Soluble in ethanol, ethyl ether, acetone, benzene
    • Soluble in dilute mineral acid, alcohol, and ether; insoluble in water
    • In water, 1.3X10+4 mg/L at 25 °C
    • Solubility in water, g/100ml at 20 °C: 1.5 (moderate)
    • (77 °F): 1%

  • Synonyms

    • O-ANISIDINE
    • 2-Methoxyaniline
    • 90-04-0
    • 2-Anisidine
    • 2-Aminoanisole
    • o-Aminoanisole
    • o-Methoxyaniline
    • Ortho-anisidine
    • Benzenamine, 2-methoxy-
    • 2-Methoxybenzenamine
    • o-Anisylamine
    • 1-Amino-2-methoxybenzene
    • o-Methoxyphenylamine
    • ortho-Aminoanisole
    • 2-Methoxy-1-aminobenzene
    • ortho-Methoxyaniline
    • 2-Methoxy-phenylamine
    • 2-methoxyphenylamine
    • ortho-Methoxyphenylamine
    • Anisidine, o-
    • NSC 3122
    • CCRIS 768
    • HSDB 2073
    • 2-METHOXY-ANILINE
    • o-Aminophenol methyl ether
    • EINECS 201-963-1
    • UNII-NUX042F201
    • BRN 0386210
    • 2-Aminomethoxybenzene
    • DTXSID5023877
    • Aniline, 2-methoxy-
    • CHEBI:82288
    • AI3-08584
    • NSC-3122
    • O-ANISIDINE [HSDB]
    • UN 2431 (Salt/Mix)
    • ORTHO-ANISIDINE [IARC]
    • DTXCID803877
    • EC 201-963-1
    • NUX042F201
    • 4-13-00-00806 (Beilstein Handbook Reference)
    • MFCD00007688
    • ORTHO-ANISIDINE (IARC)
    • O-Anisidina
    • CAS-90-04-0
    • ORTHO ANISIDINE
    • oAminoanisole
    • oAnisylamine
    • oMethoxyaniline
    • 2methoxyaniline
    • 2Aminoanisole
    • o-anisidin
    • 2-methoxyanilin
    • 2Anisidine
    • orthoAminoanisole
    • 2-Methoxianalina
    • 2-methoxylaniline
    • oMethoxyphenylamine
    • orthoMethoxyaniline
    • 2-methyloxyaniline
    • 2-methoxy aniline
    • 2-Metossi-anilina
    • 2Methoxybenzenamine
    • 2-methyoxy-aniline
    • 2-methoxybenzeneamine
    • 1Amino2methoxybenzene
    • 2Methoxy1aminobenzene
    • 2-(methyloxy)aniline
    • 2-methoxyphenyl amine
    • Benzenamine, 2methoxy
    • orthoMethoxyphenylamine
    • 2-amino-methoxybenzene
    • (2-methoxyphenyl)amine
    • 2-(methyloxy) aniline
    • o-Anisidina (Spanish)
    • Benzolamin, 2-methoxy-
    • (2-methoxyphenyl)-amine
    • o-Anisidine, >=99%
    • 2-Methoxyanilin (German)
    • 2-Methoxianalina (German)
    • Amine, o-methoxyphenylamine
    • SCHEMBL14598
    • o-Anisidine (ACGIH:OSHA)
    • 2-Metossi-anilina (Italian)
    • MLS001050112
    • BIDD:GT0815
    • Benzenamine, 2-methoxy-(9CI)
    • CHEMBL1612004
    • o-Anisidine, analytical standard
    • Benzolamin, 2-methoxy-(German)
    • NSC3122
    • Tox21_201460
    • Tox21_300053
    • STL169147
    • AKOS000102650
    • NCGC00091248-01
    • NCGC00091248-02
    • NCGC00091248-03
    • NCGC00091248-04
    • NCGC00254164-01
    • NCGC00259011-01
    • AC-11739
    • AS-10980
    • BP-21350
    • SMR001216591
    • 2-Anisidine 100 microg/mL in Acetonitrile
    • DB-057180
    • A0486
    • NS00002777
    • EN300-19068
    • C19191
    • A843418
    • Q3295808
    • F2190-0439
    • 201-963-1

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 600.61
    methanol 845.34
    isopropanol 350.75
    water 22.6
    ethyl acetate 436.08
    n-propanol 453.31
    acetone 644.25
    n-butanol 314.66
    acetonitrile 838.6
    DMF 472.06
    toluene 91.7
    isobutanol 251.25
    1,4-dioxane 1544.64
    methyl acetate 501.76
    THF 1204.65
    2-butanone 417.14
    n-pentanol 229.47
    sec-butanol 243.18
    n-hexane 21.87
    ethylene glycol 198.32
    NMP 388.21
    cyclohexane 30.21
    DMSO 1330.17
    n-butyl acetate 248.64
    n-octanol 95.96
    chloroform 855.87
    n-propyl acetate 262.45
    acetic acid 872.84
    dichloromethane 884.69
    cyclohexanone 483.48
    propylene glycol 137.39
    isopropyl acetate 174.71
    DMAc 237.49
    2-ethoxyethanol 530.88
    isopentanol 211.53
    n-heptane 25.86
    ethyl formate 480.29
    1,2-dichloroethane 554.17
    n-hexanol 178.15
    2-methoxyethanol 751.86
    isobutyl acetate 126.64
    tetrachloromethane 180.94
    n-pentyl acetate 129.07
    transcutol 650.32
    n-heptanol 100.1
    ethylbenzene 46.17
    MIBK 175.1
    2-propoxyethanol 363.51
    tert-butanol 425.28
    MTBE 301.44
    2-butoxyethanol 206.52
    propionic acid 424.75
    o-xylene 61.77
    formic acid 576.47
    diethyl ether 433.35
    m-xylene 63.97
    p-xylene 61.53
    chlorobenzene 184.83
    dimethyl carbonate 139.68
    n-octane 12.47
    formamide 763.08
    cyclopentanone 667.79
    2-pentanone 292.5
    anisole 168.97
    cyclopentyl methyl ether 358.78
    gamma-butyrolactone 935.15
    1-methoxy-2-propanol 364.34
    pyridine 440.5
    3-pentanone 205.11
    furfural 689.89
    n-dodecane 9.45
    diethylene glycol 332.52
    diisopropyl ether 83.88
    tert-amyl alcohol 261.94
    acetylacetone 307.77
    n-hexadecane 10.6
    acetophenone 136.37
    methyl propionate 275.76
    isopentyl acetate 163.92
    trichloroethylene 845.22
    n-nonanol 82.62
    cyclohexanol 204.95
    benzyl alcohol 139.2
    2-ethylhexanol 97.6
    isooctanol 81.05
    dipropyl ether 148.63
    1,2-dichlorobenzene 154.42
    ethyl lactate 112.24
    propylene carbonate 390.15
    n-methylformamide 572.55
    2-pentanol 174.25
    n-pentane 25.72
    1-propoxy-2-propanol 218.84
    1-methoxy-2-propyl acetate 192.59
    2-(2-methoxypropoxy) propanol 143.58
    mesitylene 45.9
    ε-caprolactone 421.7
    p-cymene 41.19
    epichlorohydrin 1069.27
    1,1,1-trichloroethane 459.82
    2-aminoethanol 318.61
    morpholine-4-carbaldehyde 551.99
    sulfolane 853.83
    2,2,4-trimethylpentane 17.66
    2-methyltetrahydrofuran 723.61
    n-hexyl acetate 151.74
    isooctane 15.23
    2-(2-butoxyethoxy)ethanol 222.44
    sec-butyl acetate 117.2
    tert-butyl acetate 214.16
    decalin 17.88
    glycerin 247.62
    diglyme 465.79
    acrylic acid 360.15
    isopropyl myristate 59.91
    n-butyric acid 498.75
    acetyl acetate 226.12
    di(2-ethylhexyl) phthalate 54.54
    ethyl propionate 172.06
    nitromethane 1641.89
    1,2-diethoxyethane 258.54
    benzonitrile 196.36
    trioctyl phosphate 52.16
    1-bromopropane 259.73
    gamma-valerolactone 848.85
    n-decanol 62.19
    triethyl phosphate 78.54
    4-methyl-2-pentanol 91.09
    propionitrile 431.62
    vinylene carbonate 379.54
    1,1,2-trichlorotrifluoroethane 479.44
    DMS 131.06
    cumene 38.33
    2-octanol 68.4
    2-hexanone 217.59
    octyl acetate 80.73
    limonene 63.06
    1,2-dimethoxyethane 715.7
    ethyl orthosilicate 75.02
    tributyl phosphate 59.85
    diacetone alcohol 227.52
    N,N-dimethylaniline 89.66
    acrylonitrile 492.85
    aniline 172.26
    1,3-propanediol 449.5
    bromobenzene 165.95
    dibromomethane 546.05
    1,1,2,2-tetrachloroethane 518.09
    2-methyl-cyclohexyl acetate 102.51
    tetrabutyl urea 68.38
    diisobutyl methanol 63.41
    2-phenylethanol 125.48
    styrene 64.33
    dioctyl adipate 82.93
    dimethyl sulfate 224.7
    ethyl butyrate 160.79
    methyl lactate 140.03
    butyl lactate 94.12
    diethyl carbonate 110.22
    propanediol butyl ether 143.06
    triethyl orthoformate 107.03
    p-tert-butyltoluene 42.32
    methyl 4-tert-butylbenzoate 118.38
    morpholine 1082.23
    tert-butylamine 207.24
    n-dodecanol 47.58
    dimethoxymethane 436.31
    ethylene carbonate 339.28
    cyrene 156.64
    2-ethoxyethyl acetate 188.02
    2-ethylhexyl acetate 118.11
    1,2,4-trichlorobenzene 180.32
    4-methylpyridine 311.04
    dibutyl ether 109.75
    2,6-dimethyl-4-heptanol 63.41
    DEF 262.97
    dimethyl isosorbide 247.95
    tetrachloroethylene 402.69
    eugenol 123.92
    triacetin 140.94
    span 80 117.36
    1,4-butanediol 184.19
    1,1-dichloroethane 485.57
    2-methyl-1-pentanol 154.04
    methyl formate 535.23
    2-methyl-1-butanol 196.13
    n-decane 15.87
    butyronitrile 370.09
    3,7-dimethyl-1-octanol 77.82
    1-chlorooctane 64.07
    1-chlorotetradecane 24.94
    n-nonane 16.0
    undecane 11.9
    tert-butylcyclohexane 20.23
    cyclooctane 13.18
    cyclopentanol 313.29
    tetrahydropyran 785.23
    tert-amyl methyl ether 174.97
    2,5,8-trioxanonane 280.31
    1-hexene 74.65
    2-isopropoxyethanol 284.9
    2,2,2-trifluoroethanol 348.14
    methyl butyrate 251.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Tulip sylvestre Tulipa sylvestris L., fam. Liliaceae 2.79%