Nopinol

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  • Identifiers

    CAS number
    28664-08-6

    Molecular formula
    C9H16O

    SMILES
    CC1(C2CCC(C1C2)O)C

    Safety labels

  • Odor profile

    Fragrance
    Herbal 78.14%
    Camphoreous 74.88%
    Mint 72.48%
    Woody 70.23%
    Pine 67.16%
    Sweet 63.32%
    Cooling 57.7%
    Balsamic 51.62%
    Earthy 51.15%
    Fresh 49.51%

     

    Flavor
    Herbal 49.26%
    Sweet 48.71%
    Minty 45.19%
    Pine 42.77%
    Camphor 39.28%
    Earthy 38.49%
    Balsam 36.72%
    Fresh 36.67%
    Woody 35.07%
    Herb 33.6%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    8.8 (weak base)

    Molecular weight
    140.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    216°C

    Flash point

    • 69.81 ˚C est.

  • Synonyms

    • 28664-08-6
    • 6,6-DIMETHYLBICYCLO[3.1.1]HEPTAN-2-OL
    • 6,6-Dimethylbicyclo(3.1.1)heptan-2-ol
    • nopinol
    • DTXSID80951324
    • RefChem:927890
    • DTXCID301379445
    • 249-135-9
    • EINECS 249-135-9
    • NSC251000
    • 7,7-dimethylbicyclo[3.1.1]heptan-2-ol
    • SCHEMBL11695798
    • DEDZBEBBIUTZAJ-UHFFFAOYSA-N
    • NSC 251000
    • NSC-251000
    • NS00049098
    • 6,6-DIMETHYLBICYLCO[3.1.1]HEPTAN-2-OL
    • 28664-08-6

  • Applications

    Nopinol (CAS 28664-08-6) is primarily used as an intermediate in organic synthesis and as a solvent or processing aid in various industrial formulations. In coatings and inks, it can serve as a supplementary solvent or processing additive to improve solubility, uniformity, and compatibility of formulation components. In polymer and plastics systems, it may act as a processing aid or stabilizer, helping to adjust processing properties such as viscosity and compatibility with other additives. In adhesives and cleaning formulations, it can function as a solvent or carrier for other ingredients. Its use is subject to local regulations and formulation limits, and it may be evaluated for additional industrial applications as appropriate.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 778.92
    methanol 918.28
    isopropanol 606.06
    water 14.44
    ethyl acetate 458.77
    n-propanol 581.99
    acetone 498.47
    n-butanol 511.9
    acetonitrile 591.14
    DMF 288.81
    toluene 143.71
    isobutanol 354.45
    1,4-dioxane 932.25
    methyl acetate 400.05
    THF 1258.72
    2-butanone 317.81
    n-pentanol 219.7
    sec-butanol 310.59
    n-hexane 45.83
    ethylene glycol 177.22
    NMP 185.88
    cyclohexane 79.86
    DMSO 300.78
    n-butyl acetate 367.71
    n-octanol 170.6
    chloroform 809.12
    n-propyl acetate 211.22
    acetic acid 467.49
    dichloromethane 571.86
    cyclohexanone 336.24
    propylene glycol 190.31
    isopropyl acetate 278.24
    DMAc 158.96
    2-ethoxyethanol 332.73
    isopentanol 392.01
    n-heptane 56.83
    ethyl formate 289.01
    1,2-dichloroethane 333.04
    n-hexanol 453.3
    2-methoxyethanol 638.2
    isobutyl acetate 145.43
    tetrachloromethane 184.74
    n-pentyl acetate 164.2
    transcutol 1032.15
    n-heptanol 199.99
    ethylbenzene 66.72
    MIBK 239.09
    2-propoxyethanol 647.62
    tert-butanol 568.88
    MTBE 441.08
    2-butoxyethanol 317.72
    propionic acid 355.97
    o-xylene 91.14
    formic acid 274.15
    diethyl ether 544.16
    m-xylene 130.41
    p-xylene 95.15
    chlorobenzene 185.25
    dimethyl carbonate 117.48
    n-octane 24.39
    formamide 359.15
    cyclopentanone 446.13
    2-pentanone 299.21
    anisole 151.06
    cyclopentyl methyl ether 377.38
    gamma-butyrolactone 566.27
    1-methoxy-2-propanol 519.65
    pyridine 371.92
    3-pentanone 189.08
    furfural 361.39
    n-dodecane 16.55
    diethylene glycol 466.2
    diisopropyl ether 178.36
    tert-amyl alcohol 280.33
    acetylacetone 294.21
    n-hexadecane 18.14
    acetophenone 113.93
    methyl propionate 266.79
    isopentyl acetate 288.06
    trichloroethylene 528.66
    n-nonanol 144.22
    cyclohexanol 250.42
    benzyl alcohol 118.36
    2-ethylhexanol 201.08
    isooctanol 146.93
    dipropyl ether 269.5
    1,2-dichlorobenzene 157.16
    ethyl lactate 104.82
    propylene carbonate 277.03
    n-methylformamide 387.25
    2-pentanol 305.41
    n-pentane 76.5
    1-propoxy-2-propanol 434.28
    1-methoxy-2-propyl acetate 334.2
    2-(2-methoxypropoxy) propanol 209.41
    mesitylene 94.16
    ε-caprolactone 305.44
    p-cymene 72.46
    epichlorohydrin 540.46
    1,1,1-trichloroethane 368.97
    2-aminoethanol 343.73
    morpholine-4-carbaldehyde 338.94
    sulfolane 312.38
    2,2,4-trimethylpentane 33.13
    2-methyltetrahydrofuran 553.7
    n-hexyl acetate 226.49
    isooctane 44.47
    2-(2-butoxyethoxy)ethanol 340.79
    sec-butyl acetate 139.33
    tert-butyl acetate 271.18
    decalin 29.71
    glycerin 260.37
    diglyme 556.2
    acrylic acid 258.03
    isopropyl myristate 90.51
    n-butyric acid 473.23
    acetyl acetate 251.02
    di(2-ethylhexyl) phthalate 76.89
    ethyl propionate 171.99
    nitromethane 624.76
    1,2-diethoxyethane 407.45
    benzonitrile 181.63
    trioctyl phosphate 66.36
    1-bromopropane 264.02
    gamma-valerolactone 543.84
    n-decanol 107.54
    triethyl phosphate 79.4
    4-methyl-2-pentanol 218.42
    propionitrile 434.36
    vinylene carbonate 278.0
    1,1,2-trichlorotrifluoroethane 290.84
    DMS 156.21
    cumene 61.04
    2-octanol 116.07
    2-hexanone 172.45
    octyl acetate 107.65
    limonene 98.19
    1,2-dimethoxyethane 447.03
    ethyl orthosilicate 85.12
    tributyl phosphate 79.56
    diacetone alcohol 276.04
    N,N-dimethylaniline 91.43
    acrylonitrile 403.31
    aniline 223.41
    1,3-propanediol 465.96
    bromobenzene 169.36
    dibromomethane 415.24
    1,1,2,2-tetrachloroethane 369.07
    2-methyl-cyclohexyl acetate 131.6
    tetrabutyl urea 77.48
    diisobutyl methanol 143.27
    2-phenylethanol 203.56
    styrene 73.19
    dioctyl adipate 96.71
    dimethyl sulfate 118.35
    ethyl butyrate 214.82
    methyl lactate 148.32
    butyl lactate 137.63
    diethyl carbonate 135.77
    propanediol butyl ether 224.7
    triethyl orthoformate 153.06
    p-tert-butyltoluene 79.24
    methyl 4-tert-butylbenzoate 140.55
    morpholine 839.54
    tert-butylamine 435.05
    n-dodecanol 80.08
    dimethoxymethane 393.32
    ethylene carbonate 270.22
    cyrene 123.14
    2-ethoxyethyl acetate 248.79
    2-ethylhexyl acetate 202.71
    1,2,4-trichlorobenzene 164.1
    4-methylpyridine 274.17
    dibutyl ether 181.35
    2,6-dimethyl-4-heptanol 143.27
    DEF 201.0
    dimethyl isosorbide 289.65
    tetrachloroethylene 297.52
    eugenol 141.46
    triacetin 172.96
    span 80 178.25
    1,4-butanediol 141.13
    1,1-dichloroethane 423.7
    2-methyl-1-pentanol 158.2
    methyl formate 288.14
    2-methyl-1-butanol 273.54
    n-decane 30.48
    butyronitrile 432.17
    3,7-dimethyl-1-octanol 162.5
    1-chlorooctane 91.52
    1-chlorotetradecane 35.47
    n-nonane 30.17
    undecane 21.65
    tert-butylcyclohexane 32.61
    cyclooctane 33.98
    cyclopentanol 305.1
    tetrahydropyran 711.84
    tert-amyl methyl ether 208.04
    2,5,8-trioxanonane 329.69
    1-hexene 119.39
    2-isopropoxyethanol 233.68
    2,2,2-trifluoroethanol 199.36
    methyl butyrate 187.84

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction