N,N'-Hexamethylenebis(3,5-di-tert-butyl-4-hydroxyhydrocinnamamide)

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  • Identifiers

    CAS number
    23128-74-7

    Molecular formula
    C40H64N2O4

    SMILES
    CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CCC(=O)NCCCCCCNC(=O)CCC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 43.58%
    Cooling 34.61%
    Mint 34.42%
    Animal 29.88%
    Dry 28.99%
    Herbal 27.09%
    Savory 25.29%
    Fruity 24.96%
    Grapefruit 24.33%
    Fatty 23.08%

     

    Flavor
    Bitter 34.79%
    Bland 31.78%
    Mild 31.36%
    Odorless 27.52%
    Herbal 26.61%
    Woody 21.9%
    Cedarleaf 20.21%
    Green pepper 20.09%
    Thymol 19.98%
    Parsley 19.91%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.0

    pKa est.
    7.51 (neutral)

    Molecular weight
    636.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1117°C

    Flash point

    • 270.13 ˚C est.

  • Synonyms

    • 23128-74-7
    • Antioxidant 1098
    • Benzenepropanamide, N,N'-1,6-hexanediylbis(3,5-bis(1,1-dimethylethyl)-4-hydroxy-
    • EINECS 245-442-7
    • DTXSID5044233
    • n,n'-hexamethylenebis(3,5-di-tert-butyl-4-hydroxyhydrocinnamamide)
    • N,N'-Hexane-1,6-diylbis[3-(3,5-di-tert-butyl-4-hydroxyphenylpropionamide]
    • 918T54D300
    • DTXCID3024233
    • EC 245-442-7
    • Benzenepropanamide, N,N'-1,6-hexanediylbis[3,5-bis(1,1-dimethylethyl)-4-hydroxy-
    • N,N'-Hexane-1,6-diylbis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionamide)
    • N,N'-Hexane-1,6-diylbis(3-(3,5-di-tert-butyl-4-hydroxyphenylpropionamide)
    • RefChem:821958
    • Irganox 1098
    • N,N'-(Hexane-1,6-diyl)bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide)
    • 3,3'-bis(3,5-di-tert-butyl-4-hydroxyphenyl)-N,N'-hexamethylenedipropionamide
    • MFCD00134697
    • C40H64N2O4
    • 3-(3,5-ditert-butyl-4-hydroxyphenyl)-N-[6-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoylamino]hexyl]propanamide
    • Benzenepropanamide,N,N'-1,6-hexanediylbis[3,5-bis(1,1-dimethylethyl)-4-hydroxy-
    • N,N'-(Hexane-1,6-diyl)bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide]
    • 3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)-N-{6-[3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPANAMIDO]HEXYL}PROPANAMIDE
    • 3,3-Bis(3,5-di-tert-butyl-4-hydroxyphenyl)-N,N-hexamethylenedipropionamide
    • UNII-918T54D300
    • n,n'-hexane-1,6-diylbis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide]
    • SCHEMBL77798
    • SCHEMBL2776099
    • SCHEMBL27224487
    • MSK3131
    • CHEBI:193589
    • Tox21_303983
    • STL598920
    • AKOS001704194
    • FA33346
    • s12009
    • NCGC00356955-01
    • 3-(3,5-ditert-butyl-4-hydroxy-phenyl)-N-[6-[3-(3,5-ditert-butyl-4-hydroxy-phenyl)propanoylamino]hexyl]propanamide
    • AS-12192
    • SY237553
    • CAS-23128-74-7
    • CS-0113613
    • H1704
    • NS00002810
    • 128B747
    • Q21099615
    • N,N'-bis(3,5-di-t-butyl-4-hydroxyphenylpropionyl)-hexamethylenediamine
    • N,N'-di(3,5-di-tert-butyl-4-hydroxyphenylproprionyl)hexamethylenediamine
    • BENZENEPROPANAMIDE, N,N'-1,6-HEXANEDIYLBIS(3,5-BIS(1,1- DIMETHYLETHYL)-4-HYDROXY-
    • N,N'-Bis-(3,5-di-tert-butyl-4-hydroxyphenylpropionyl)-hexamet hylene-diamine
    • N,N'-bis[beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl]hexamethylenediamine
    • N,N'-HEXANE-1,6-DIYLBIS(3-(3,5-DI-TERT-BUTYL-4- HYDROXYPHENYL)PROPIONAMIDE)
    • N,N\'-bis[beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl]hexamethylenediamine
    • 245-442-7
    • N,N inverted exclamation mark -(Hexane-1,6-diyl)bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide]
    • 23128-74-7

  • Applications

    N,N'-Hexamethylenebis(3,5-di-tert-butyl-4-hydroxyhydrocinnamamide) (CAS 23128-74-7) is commonly used as a hindered phenolic antioxidant and stabilizer in polymer formulations. In practice it serves as a processing stabilizer in polyolefins (PE, PP), PVC and polyesters to resist thermal-oxidative degradation. It is also employed in coatings and inks to prevent discoloration and surface degradation. Additionally, it is used in adhesives and sealants to extend service life during cure and in rubbers and elastomers to improve aging resistance. Finally, it may be used in electronics encapsulation materials to enhance thermal stability during operation.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 93.12
    methanol 47.29
    isopropanol 35.1
    water 0.05
    ethyl acetate 8.39
    n-propanol 74.62
    acetone 33.85
    n-butanol 46.62
    acetonitrile 7.39
    DMF 67.63
    toluene 9.03
    isobutanol 33.98
    1,4-dioxane 30.98
    methyl acetate 8.13
    THF 145.67
    2-butanone 36.69
    n-pentanol 48.09
    sec-butanol 32.95
    n-hexane 1.75
    ethylene glycol 5.32
    NMP 91.04
    cyclohexane 0.79
    DMSO 65.92
    n-butyl acetate 14.8
    n-octanol 15.84
    chloroform 47.28
    n-propyl acetate 17.17
    acetic acid 29.19
    dichloromethane 36.05
    cyclohexanone 50.58
    propylene glycol 20.92
    isopropyl acetate 6.9
    DMAc 70.32
    2-ethoxyethanol 66.67
    isopentanol 20.98
    n-heptane 1.01
    ethyl formate 20.96
    1,2-dichloroethane 22.53
    n-hexanol 22.1
    2-methoxyethanol 73.36
    isobutyl acetate 14.09
    tetrachloromethane 4.94
    n-pentyl acetate 25.63
    transcutol 54.34
    n-heptanol 20.57
    ethylbenzene 6.57
    MIBK 12.7
    2-propoxyethanol 58.93
    tert-butanol 14.41
    MTBE 10.05
    2-butoxyethanol 54.67
    propionic acid 18.2
    o-xylene 3.59
    formic acid 14.91
    diethyl ether 13.45
    m-xylene 4.14
    p-xylene 8.06
    chlorobenzene 13.1
    dimethyl carbonate 4.84
    n-octane 0.71
    formamide 19.43
    cyclopentanone 81.02
    2-pentanone 24.51
    anisole 13.33
    cyclopentyl methyl ether 24.49
    gamma-butyrolactone 58.69
    1-methoxy-2-propanol 55.4
    pyridine 54.07
    3-pentanone 13.97
    furfural 48.06
    n-dodecane 0.36
    diethylene glycol 21.47
    diisopropyl ether 1.85
    tert-amyl alcohol 17.14
    acetylacetone 16.41
    n-hexadecane 0.4
    acetophenone 18.25
    methyl propionate 11.58
    isopentyl acetate 13.29
    trichloroethylene 39.22
    n-nonanol 15.83
    cyclohexanol 17.82
    benzyl alcohol 25.33
    2-ethylhexanol 10.43
    isooctanol 14.26
    dipropyl ether 11.24
    1,2-dichlorobenzene 8.89
    ethyl lactate 12.19
    propylene carbonate 22.35
    n-methylformamide 41.12
    2-pentanol 15.88
    n-pentane 1.17
    1-propoxy-2-propanol 38.3
    1-methoxy-2-propyl acetate 15.94
    2-(2-methoxypropoxy) propanol 22.81
    mesitylene 1.74
    ε-caprolactone 41.89
    p-cymene 3.08
    epichlorohydrin 78.34
    1,1,1-trichloroethane 11.41
    2-aminoethanol 29.39
    morpholine-4-carbaldehyde 64.75
    sulfolane 78.69
    2,2,4-trimethylpentane 0.47
    2-methyltetrahydrofuran 52.5
    n-hexyl acetate 23.66
    isooctane 0.25
    2-(2-butoxyethoxy)ethanol 37.57
    sec-butyl acetate 9.15
    tert-butyl acetate 7.49
    decalin 0.7
    glycerin 18.59
    diglyme 50.25
    acrylic acid 13.94
    isopropyl myristate 5.97
    n-butyric acid 28.5
    acetyl acetate 3.85
    di(2-ethylhexyl) phthalate 10.51
    ethyl propionate 10.27
    nitromethane 24.88
    1,2-diethoxyethane 21.53
    benzonitrile 15.03
    trioctyl phosphate 8.13
    1-bromopropane 17.24
    gamma-valerolactone 113.93
    n-decanol 9.2
    triethyl phosphate 5.02
    4-methyl-2-pentanol 6.34
    propionitrile 11.95
    vinylene carbonate 18.33
    1,1,2-trichlorotrifluoroethane 46.23
    DMS 6.91
    cumene 4.11
    2-octanol 13.01
    2-hexanone 33.22
    octyl acetate 10.32
    limonene 4.02
    1,2-dimethoxyethane 58.62
    ethyl orthosilicate 5.82
    tributyl phosphate 7.4
    diacetone alcohol 17.86
    N,N-dimethylaniline 12.33
    acrylonitrile 13.88
    aniline 15.66
    1,3-propanediol 39.13
    bromobenzene 10.57
    dibromomethane 26.61
    1,1,2,2-tetrachloroethane 37.74
    2-methyl-cyclohexyl acetate 12.29
    tetrabutyl urea 14.42
    diisobutyl methanol 3.33
    2-phenylethanol 19.71
    styrene 7.11
    dioctyl adipate 10.44
    dimethyl sulfate 8.98
    ethyl butyrate 10.25
    methyl lactate 11.78
    butyl lactate 26.32
    diethyl carbonate 4.71
    propanediol butyl ether 48.53
    triethyl orthoformate 9.47
    p-tert-butyltoluene 2.75
    methyl 4-tert-butylbenzoate 18.41
    morpholine 70.92
    tert-butylamine 6.12
    n-dodecanol 5.14
    dimethoxymethane 36.4
    ethylene carbonate 14.86
    cyrene 35.44
    2-ethoxyethyl acetate 26.84
    2-ethylhexyl acetate 11.33
    1,2,4-trichlorobenzene 12.5
    4-methylpyridine 37.97
    dibutyl ether 10.15
    2,6-dimethyl-4-heptanol 3.33
    DEF 25.1
    dimethyl isosorbide 34.74
    tetrachloroethylene 20.53
    eugenol 22.57
    triacetin 14.06
    span 80 26.34
    1,4-butanediol 21.69
    1,1-dichloroethane 16.94
    2-methyl-1-pentanol 25.93
    methyl formate 22.46
    2-methyl-1-butanol 26.67
    n-decane 0.92
    butyronitrile 18.43
    3,7-dimethyl-1-octanol 8.84
    1-chlorooctane 5.61
    1-chlorotetradecane 1.38
    n-nonane 0.86
    undecane 0.55
    tert-butylcyclohexane 0.77
    cyclooctane 0.28
    cyclopentanol 34.61
    tetrahydropyran 41.8
    tert-amyl methyl ether 9.38
    2,5,8-trioxanonane 27.46
    1-hexene 9.54
    2-isopropoxyethanol 38.2
    2,2,2-trifluoroethanol 6.89
    methyl butyrate 19.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction