N,N'-Ethylenebispalmitamide

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  • Identifiers

    CAS number
    5518-18-3

    Molecular formula
    C34H68N2O2

    SMILES
    CCCCCCCCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 46.23%
    Fatty 37.25%
    Meaty 35.03%
    Savory 33.65%
    Fishy 31.67%
    Odorless 30.81%
    Oily 28.62%
    Animal 25.45%
    Cooling 21.15%
    Woody 19.35%

     

    Flavor
    Bland 38.48%
    Odorless 32.31%
    Mild 31.83%
    Faint 28.76%
    Fatty 27.48%
    Waxy 24.75%
    Slightly waxy 22.71%
    Delicate 20.89%
    Bay oil 20.85%
    Beer 19.71%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    13.5

    pKa est.
    9.91 (weak base)

    Molecular weight
    536.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    677°C

    Flash point

    • 277.05 ˚C est.

  • Synonyms

    • Hexadecanamide, N,N'-1,2-ethanediylbis-
    • n,n'-ethylenebispalmitamide
    • N,N'-Ethane-1,2-diylbishexadecan-1-amide
    • N,N'-Ethylenebis(palmitamide)
    • 1,2-Ethylenediamine di(palmitoylamide)
    • Hexadecanamide, N,N'-ethylenebis-
    • EINECS 226-864-0
    • DP8GB19Z7H
    • NSC 131416
    • ethylene bispalmitamide
    • NSC-131416
    • DTXSID4029272
    • n,n'-ethylenebispalmitic acid amide
    • 1,2-BIS(HEXADECANAMIDO)ETHANE
    • N,N'-ETHYLENEBIS(PALMITIC AMIDE)
    • RefChem:821956
    • DTXCID209272
    • 5518-18-3
    • N,N'-1,2-Ethanediyl bis-hexadecanamide
    • N-[2-(hexadecanoylamino)ethyl]hexadecanamide
    • ethylene bis-palmitamide
    • MFCD19705254
    • UNII-DP8GB19Z7H
    • C34H68N2O2
    • N,N'-(Ethane-1,2-diyl)dipalmitamide; 1,2-Bis(hexadecanamido)ethane; N,N'-Dipalmitoylethylenediamine
    • NSC131416
    • N,N'-ethane-1,2-diyldihexadecanamide
    • Hexadecanamide,N,N'-1,2-ethanediylbis-
    • N-(2-HEXADECANAMIDOETHYL)HEXADECANAMIDE
    • SCHEMBL542604
    • N,N'- Dipalmitoylethylendiamin
    • UAXZKOFYXXDTFH-UHFFFAOYSA-N
    • AKOS037645874
    • AS-64391
    • N,N'-(Ethane-1,2-diyl)dihexadecanamide
    • CS-0188501
    • NS00019611
    • N,N'-1,2-ETHANEDIYLBIS-HEXADECANAMIDE
    • A12630
    • Q27276519
    • 5518-18-3

  • Applications

    N,N'-Ethylenebispalmitamide (CAS 5518-18-3) is a diamide of palmitic acid with ethylenediamine and is used primarily as a wax-like processing aid and slip lubricant in polymer processing and coatings, serving as a flow modifier and anti-friction additive. It is also considered an intermediate in the synthesis of specialty amides for the chemical industry. In cosmetics and personal care, it may be used as a conditioning aid or an emollient ingredient in certain formulations, subject to regulatory and formulation limits. Additionally, it can function as a processing additive in adhesives and printing inks to improve lubrication and dispersion, depending on the formulation. These applications depend on technical requirements and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.06
    methanol 1.7
    isopropanol 0.85
    water 0.05
    ethyl acetate 7.34
    n-propanol 1.56
    acetone 4.96
    n-butanol 1.67
    acetonitrile 1.62
    DMF 15.49
    toluene 4.48
    isobutanol 1.43
    1,4-dioxane 8.81
    methyl acetate 5.81
    THF 30.28
    2-butanone 8.99
    n-pentanol 2.27
    sec-butanol 1.99
    n-hexane 1.16
    ethylene glycol 0.23
    NMP 91.32
    cyclohexane 2.73
    DMSO 16.98
    n-butyl acetate 11.26
    n-octanol 4.37
    chloroform 46.66
    n-propyl acetate 11.48
    acetic acid 6.14
    dichloromethane 39.98
    cyclohexanone 34.46
    propylene glycol 0.67
    isopropyl acetate 8.07
    DMAc 56.33
    2-ethoxyethanol 5.99
    isopentanol 2.13
    n-heptane 1.12
    ethyl formate 5.11
    1,2-dichloroethane 18.19
    n-hexanol 2.02
    2-methoxyethanol 4.84
    isobutyl acetate 8.06
    tetrachloromethane 10.95
    n-pentyl acetate 22.03
    transcutol 45.01
    n-heptanol 3.62
    ethylbenzene 4.4
    MIBK 7.47
    2-propoxyethanol 6.84
    tert-butanol 1.79
    MTBE 4.91
    2-butoxyethanol 12.41
    propionic acid 4.59
    o-xylene 5.53
    formic acid 2.23
    diethyl ether 2.93
    m-xylene 3.78
    p-xylene 6.33
    chlorobenzene 10.46
    dimethyl carbonate 4.83
    n-octane 0.77
    formamide 3.46
    cyclopentanone 38.98
    2-pentanone 7.77
    anisole 7.64
    cyclopentyl methyl ether 15.37
    gamma-butyrolactone 43.54
    1-methoxy-2-propanol 5.19
    pyridine 14.32
    3-pentanone 9.64
    furfural 38.34
    n-dodecane 0.43
    diethylene glycol 2.72
    diisopropyl ether 2.18
    tert-amyl alcohol 4.01
    acetylacetone 14.59
    n-hexadecane 0.5
    acetophenone 16.09
    methyl propionate 8.01
    isopentyl acetate 13.33
    trichloroethylene 46.03
    n-nonanol 5.04
    cyclohexanol 5.13
    benzyl alcohol 4.92
    2-ethylhexanol 3.4
    isooctanol 4.06
    dipropyl ether 6.4
    1,2-dichlorobenzene 16.86
    ethyl lactate 7.45
    propylene carbonate 29.42
    n-methylformamide 5.0
    2-pentanol 1.62
    n-pentane 0.59
    1-propoxy-2-propanol 8.82
    1-methoxy-2-propyl acetate 15.37
    2-(2-methoxypropoxy) propanol 18.26
    mesitylene 3.22
    ε-caprolactone 39.3
    p-cymene 4.26
    epichlorohydrin 31.26
    1,1,1-trichloroethane 26.62
    2-aminoethanol 0.83
    morpholine-4-carbaldehyde 33.48
    sulfolane 101.31
    2,2,4-trimethylpentane 1.19
    2-methyltetrahydrofuran 20.01
    n-hexyl acetate 21.21
    isooctane 0.44
    2-(2-butoxyethoxy)ethanol 18.32
    sec-butyl acetate 10.77
    tert-butyl acetate 13.67
    decalin 2.0
    glycerin 1.76
    diglyme 46.14
    acrylic acid 4.34
    isopropyl myristate 6.49
    n-butyric acid 8.6
    acetyl acetate 8.2
    di(2-ethylhexyl) phthalate 8.73
    ethyl propionate 11.28
    nitromethane 12.67
    1,2-diethoxyethane 15.71
    benzonitrile 7.04
    trioctyl phosphate 5.47
    1-bromopropane 8.69
    gamma-valerolactone 55.64
    n-decanol 2.96
    triethyl phosphate 14.74
    4-methyl-2-pentanol 1.78
    propionitrile 2.37
    vinylene carbonate 23.0
    1,1,2-trichlorotrifluoroethane 34.86
    DMS 12.46
    cumene 3.85
    2-octanol 3.68
    2-hexanone 11.32
    octyl acetate 8.19
    limonene 6.75
    1,2-dimethoxyethane 17.48
    ethyl orthosilicate 14.09
    tributyl phosphate 8.35
    diacetone alcohol 12.52
    N,N-dimethylaniline 8.37
    acrylonitrile 2.94
    aniline 4.48
    1,3-propanediol 1.44
    bromobenzene 12.94
    dibromomethane 21.86
    1,1,2,2-tetrachloroethane 48.79
    2-methyl-cyclohexyl acetate 17.87
    tetrabutyl urea 13.99
    diisobutyl methanol 2.85
    2-phenylethanol 4.79
    styrene 4.44
    dioctyl adipate 13.89
    dimethyl sulfate 18.29
    ethyl butyrate 15.16
    methyl lactate 5.83
    butyl lactate 18.19
    diethyl carbonate 9.97
    propanediol butyl ether 10.64
    triethyl orthoformate 17.61
    p-tert-butyltoluene 4.02
    methyl 4-tert-butylbenzoate 26.23
    morpholine 11.88
    tert-butylamine 1.45
    n-dodecanol 1.93
    dimethoxymethane 7.01
    ethylene carbonate 16.95
    cyrene 23.21
    2-ethoxyethyl acetate 25.22
    2-ethylhexyl acetate 13.0
    1,2,4-trichlorobenzene 23.4
    4-methylpyridine 13.02
    dibutyl ether 9.88
    2,6-dimethyl-4-heptanol 2.85
    DEF 16.2
    dimethyl isosorbide 43.63
    tetrachloroethylene 31.28
    eugenol 19.6
    triacetin 31.77
    span 80 15.05
    1,4-butanediol 1.01
    1,1-dichloroethane 13.71
    2-methyl-1-pentanol 3.47
    methyl formate 4.46
    2-methyl-1-butanol 2.59
    n-decane 1.08
    butyronitrile 2.84
    3,7-dimethyl-1-octanol 4.62
    1-chlorooctane 5.28
    1-chlorotetradecane 1.49
    n-nonane 0.98
    undecane 0.63
    tert-butylcyclohexane 1.44
    cyclooctane 1.04
    cyclopentanol 5.56
    tetrahydropyran 12.04
    tert-amyl methyl ether 7.55
    2,5,8-trioxanonane 26.98
    1-hexene 2.69
    2-isopropoxyethanol 5.41
    2,2,2-trifluoroethanol 5.35
    methyl butyrate 16.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction