N,N-DIMETHYL-p-TOLUIDINE

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  • Identifiers

    CAS number
    99-97-8

    Molecular formula
    C9H13N

    SMILES
    CC1=CC=C(C=C1)N(C)C

    Safety labels

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Floral 48.06%
    Green 42.11%
    Sweet 36.71%
    Herbal 34.92%
    Woody 34.33%
    Animal 33.01%
    Earthy 31.79%
    Citrus 28.86%
    Fruity 28.65%
    Fresh 28.14%

     

    Flavor
    Herbal 42.88%
    Spicy 37.92%
    Woody 35.95%
    Floral 33.14%
    Fruity 32.91%
    Green 30.69%
    Citrus 29.25%
    Earthy 27.33%
    Spice 25.99%
    Herb 25.68%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.8

    pKa est.
    5.48 (weak acid)

    Molecular weight
    135.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point

    • 211 °C
    • 215 °C

    Flash point

    • 71.03 ˚C est.
    • 76 °C (closed cup)
    • 83 °C

    Solubility expt.

    • In water, 455 mg/L
    • In water, 650 mg/L at 37 °C
    • Miscible with ethanol, ethyl ether; soluble in carbon tetrachloride
    • Solubility in water, g/l at 37 °C: 0.65 (very slightly soluble)

  • Synonyms

    • N,N-Dimethyl-p-toluidine
    • N,N,4-TRIMETHYLANILINE
    • 99-97-8
    • Dimethyl-p-toluidine
    • Benzenamine, N,N,4-trimethyl-
    • Dimethyl-4-toluidine
    • N,N-Dimethyl-4-methylaniline
    • N,N,4-Trimethylbenzenamine
    • p-(Dimethylamino)toluene
    • p-Methyl-N,N-dimethylaniline
    • N,N-Dimethyl-p-tolylamine
    • p,N,N-Trimethylaniline
    • p-Toluidine, N,N-dimethyl-
    • NSC 1785
    • Dimetil-p-toluidina
    • 4-Dimethylaminotoluene
    • dimethyltolylamine
    • Dimetil-p-toluidina [Italian]
    • CCRIS 1001
    • 1-(Dimethylamino)-4-methylbenzene
    • N,N-Dimethyl-4-toluidine
    • EINECS 202-805-4
    • UNII-S8XC5939VU
    • S8XC5939VU
    • DTXSID0021832
    • HSDB 8202
    • NSC-1785
    • 4,N,N-Trimethylaniline
    • DTXCID401832
    • N,N-Dimethyl-p-methylphenylamine
    • EC 202-805-4
    • N,N-DIMETHYL-P-TOLUIDINE [IARC]
    • NL 65-100
    • N,N-Dimethyl-para-toluidine
    • aniline, N,N,4-trimethyl-
    • p-N,N-Trimethylaniline
    • CAS-99-97-8
    • N,N-DIMETHYL-P-TOLUIDINE (IARC)
    • dimethyl-para-toluidine
    • MFCD00008316
    • Dimetilptoluidina
    • Benzeneamine,N,N,4-trimethyl-
    • Dimethylptoluidine
    • N,NDimethylptoluidine
    • N,4-Trimethylaniline
    • N,NDimethylptolylamine
    • p,N,NTrimethylaniline
    • N,N,4Trimethylaniline
    • p(Dimethylamino)toluene
    • pMethylN,Ndimethylaniline
    • N,NDimethyl4methylaniline
    • dimethyl-(p-tolyl)-amine
    • Benzenamine,N,4-trimethyl-
    • SCHEMBL28378
    • Benzenamine, N,N,4trimethyl
    • MLS001050174
    • Benzenamine, N,N,4-trimethyl
    • 4-dimethylamino-1-methylbenzene
    • 4,N,N-Trimethylaniline, 99%
    • CHEMBL1462714
    • N,N-DIMETHYL-P-TOLUIDENE
    • DIMETHYLTOLYLAMINE [INCI]
    • NSC1785
    • N,N-DIMETHYL-1,4-TOLUIDINE
    • Tox21_201370
    • Tox21_300062
    • AC-368
    • AKOS015915159
    • NCGC00091397-01
    • NCGC00091397-02
    • NCGC00091397-03
    • NCGC00254201-01
    • NCGC00258922-01
    • SMR001216586
    • D0807
    • NS00002247
    • E75885
    • EN300-7266829
    • 4,N,N-Trimethylaniline, purum, >=98.0% (GC)
    • Q2051705
    • Z1002998236
    • platinum(2+); 4-(1H-pyrazol-4-ylmethyl)-1H-pyrazole; tetrachloride
    • 202-805-4

  • Applications

    N,N-DIMETHYL-p-TOLUIDINE (CAS 99-97-8) is primarily used as a reactive tertiary amine catalyst in epoxy resin formulations, accelerating curing at ambient or elevated temperatures. It also serves as a catalyst/accelerator in polyurethane systems. As an arylamine derivative, it serves as an intermediate for the synthesis of dyes and pigments and related specialty chemicals. In coatings and adhesives, it may function as a processing aid or solvent component in formulation work. It is also used as a building block in organic synthesis for other industrial specialty chemicals. All uses depend on formulation specifics and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 366.22
    methanol 292.86
    isopropanol 181.51
    water 3.0
    ethyl acetate 278.24
    n-propanol 283.53
    acetone 160.45
    n-butanol 288.53
    acetonitrile 304.11
    DMF 217.7
    toluene 180.75
    isobutanol 152.97
    1,4-dioxane 685.3
    methyl acetate 237.64
    THF 508.44
    2-butanone 190.93
    n-pentanol 168.17
    sec-butanol 174.23
    n-hexane 38.23
    ethylene glycol 72.65
    NMP 173.03
    cyclohexane 95.94
    DMSO 174.88
    n-butyl acetate 250.15
    n-octanol 82.02
    chloroform 1020.11
    n-propyl acetate 126.32
    acetic acid 281.97
    dichloromethane 816.48
    cyclohexanone 261.37
    propylene glycol 100.04
    isopropyl acetate 103.81
    DMAc 186.3
    2-ethoxyethanol 218.36
    isopentanol 158.23
    n-heptane 80.74
    ethyl formate 250.88
    1,2-dichloroethane 327.49
    n-hexanol 301.11
    2-methoxyethanol 360.73
    isobutyl acetate 78.72
    tetrachloromethane 227.59
    n-pentyl acetate 89.09
    transcutol 424.87
    n-heptanol 105.55
    ethylbenzene 75.38
    MIBK 66.0
    2-propoxyethanol 329.98
    tert-butanol 194.37
    MTBE 168.21
    2-butoxyethanol 154.14
    propionic acid 201.46
    o-xylene 98.12
    formic acid 114.99
    diethyl ether 275.58
    m-xylene 88.28
    p-xylene 97.4
    chlorobenzene 209.41
    dimethyl carbonate 67.82
    n-octane 18.99
    formamide 153.91
    cyclopentanone 234.25
    2-pentanone 137.06
    anisole 146.62
    cyclopentyl methyl ether 192.59
    gamma-butyrolactone 292.86
    1-methoxy-2-propanol 196.68
    pyridine 469.98
    3-pentanone 128.45
    furfural 350.12
    n-dodecane 12.94
    diethylene glycol 203.72
    diisopropyl ether 50.15
    tert-amyl alcohol 162.95
    acetylacetone 116.11
    n-hexadecane 14.42
    acetophenone 107.51
    methyl propionate 167.53
    isopentyl acetate 163.06
    trichloroethylene 593.81
    n-nonanol 76.96
    cyclohexanol 186.89
    benzyl alcohol 126.99
    2-ethylhexanol 159.71
    isooctanol 67.07
    dipropyl ether 228.82
    1,2-dichlorobenzene 165.65
    ethyl lactate 64.27
    propylene carbonate 208.99
    n-methylformamide 171.1
    2-pentanol 131.71
    n-pentane 52.32
    1-propoxy-2-propanol 207.47
    1-methoxy-2-propyl acetate 162.37
    2-(2-methoxypropoxy) propanol 108.31
    mesitylene 48.87
    ε-caprolactone 237.35
    p-cymene 74.3
    epichlorohydrin 385.3
    1,1,1-trichloroethane 366.49
    2-aminoethanol 163.94
    morpholine-4-carbaldehyde 280.51
    sulfolane 208.81
    2,2,4-trimethylpentane 21.01
    2-methyltetrahydrofuran 378.41
    n-hexyl acetate 114.04
    isooctane 12.19
    2-(2-butoxyethoxy)ethanol 157.46
    sec-butyl acetate 74.39
    tert-butyl acetate 92.03
    decalin 30.61
    glycerin 112.09
    diglyme 310.0
    acrylic acid 169.94
    isopropyl myristate 50.53
    n-butyric acid 296.23
    acetyl acetate 152.85
    di(2-ethylhexyl) phthalate 56.0
    ethyl propionate 114.63
    nitromethane 325.68
    1,2-diethoxyethane 215.2
    benzonitrile 174.12
    trioctyl phosphate 37.79
    1-bromopropane 263.23
    gamma-valerolactone 345.35
    n-decanol 57.77
    triethyl phosphate 78.57
    4-methyl-2-pentanol 58.09
    propionitrile 259.18
    vinylene carbonate 234.59
    1,1,2-trichlorotrifluoroethane 285.61
    DMS 88.56
    cumene 51.45
    2-octanol 53.51
    2-hexanone 105.82
    octyl acetate 70.99
    limonene 110.7
    1,2-dimethoxyethane 333.54
    ethyl orthosilicate 85.14
    tributyl phosphate 47.07
    diacetone alcohol 97.82
    N,N-dimethylaniline 90.22
    acrylonitrile 251.14
    aniline 217.65
    1,3-propanediol 208.55
    bromobenzene 211.79
    dibromomethane 540.81
    1,1,2,2-tetrachloroethane 441.78
    2-methyl-cyclohexyl acetate 117.27
    tetrabutyl urea 55.43
    diisobutyl methanol 71.25
    2-phenylethanol 157.75
    styrene 102.74
    dioctyl adipate 73.37
    dimethyl sulfate 71.99
    ethyl butyrate 174.37
    methyl lactate 75.56
    butyl lactate 63.21
    diethyl carbonate 128.06
    propanediol butyl ether 85.42
    triethyl orthoformate 135.2
    p-tert-butyltoluene 71.04
    methyl 4-tert-butylbenzoate 93.06
    morpholine 675.99
    tert-butylamine 149.37
    n-dodecanol 45.93
    dimethoxymethane 177.3
    ethylene carbonate 195.71
    cyrene 100.19
    2-ethoxyethyl acetate 129.74
    2-ethylhexyl acetate 148.36
    1,2,4-trichlorobenzene 198.81
    4-methylpyridine 318.75
    dibutyl ether 110.61
    2,6-dimethyl-4-heptanol 71.25
    DEF 162.8
    dimethyl isosorbide 189.63
    tetrachloroethylene 334.87
    eugenol 93.52
    triacetin 101.81
    span 80 112.17
    1,4-butanediol 76.74
    1,1-dichloroethane 354.64
    2-methyl-1-pentanol 123.3
    methyl formate 133.69
    2-methyl-1-butanol 161.3
    n-decane 23.15
    butyronitrile 289.93
    3,7-dimethyl-1-octanol 70.72
    1-chlorooctane 67.86
    1-chlorotetradecane 27.34
    n-nonane 22.61
    undecane 16.51
    tert-butylcyclohexane 26.68
    cyclooctane 30.28
    cyclopentanol 157.23
    tetrahydropyran 518.35
    tert-amyl methyl ether 121.48
    2,5,8-trioxanonane 211.01
    1-hexene 116.89
    2-isopropoxyethanol 125.96
    2,2,2-trifluoroethanol 91.65
    methyl butyrate 146.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction