N,N'-bis(3-aminopropyl)ethylenediamine

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  • Identifiers

    CAS number
    10563-26-5

    Molecular formula
    C8H22N4

    SMILES
    C(CN)CNCCNCCCN

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 86.77%
    Cheesy 49.56%
    Ripe 44.73%
    Odorless 38.62%
    Animal 32.17%
    Meaty 22.91%
    Savory 20.19%
    Pungent 16.09%
    Cooling 13.68%
    Oily 13.36%

     

    Flavor
    Odorless 30.17%
    Ammoniacal 26.3%
    Fishy 24.68%
    Sulfurous 21.13%
    Bland 20.9%
    Meaty 19.49%
    Glue 19.23%
    Mild 19.03%
    Skunky 18.93%
    Sulfury 18.76%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.8

    pKa est.
    6.0 (neutral)

    Molecular weight
    174.29 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    306°C

    Flash point

    • 147.85 ˚C est.

  • Synonyms

    • 10563-26-5
    • N,N'-Bis(3-aminopropyl)ethylenediamine
    • 1,5,8,12-Tetraazadodecane
    • 1,3-Propanediamine, N,N''-1,2-ethanediylbis-
    • N,N'-Bis(3-aminopropyl)-1,2-diaminoethane
    • N,N'-Bis(gamma-aminopropyl)diaminoethane
    • N,N'-Di(3-aminopropyl)-1,2-ethylenediamine
    • 1,3-Propanediamine, N,N''-ethylenebis-
    • EINECS 234-147-9
    • NSC 180823
    • 0EXW8894XX
    • 4,7-diazadecane-1,10-diamine
    • N4 AMINE
    • NSC-180823
    • DTXSID2065127
    • EC 234-147-9
    • 1,3-Propanediamine, N1,N1'-1,2-ethanediylbis-
    • 3,2,3-TET
    • BIS(3-AMINOPROPYL)ETHYLENEDIAMINE, N,N'-
    • N,N'-BIS(.GAMMA.-AMINOPROPYL)DIAMINOETHANE
    • N-(2-(3-AMINOPROPYLAMINO)ETHYL)-1,3-PROPANEDIAMINE
    • RefChem:821772
    • 1,5,8,12Tetraazadodecane
    • N,N'Diaminopropylethylenediamine
    • DTXCID3032969
    • N,N'Bis(3aminopropyl)diaminoethane
    • 1,3Propanediamine, N,N''ethylenebis
    • N,N'Bis(gammaaminopropyl)diaminoethane
    • N,N'Bis(3aminopropyl)1,2diaminoethane
    • N,N'Di(3aminopropyl)1,2ethylenediamine
    • 1,3Propanediamine, N,N''1,2ethanediylbis
    • 1,3Propanediamine, N1,N1'1,2ethanediylbis
    • N1,N1'1,2Ethanediylbis(1,3propanediamine)
    • N(2(3Aminopropylamino)ethyl)1,3propanediamine
    • 234-147-9
    • N1,N1'-(Ethane-1,2-diyl)bis(propane-1,3-diamine)
    • 1,2-Bis(3-aminopropylamino)ethane
    • 3,2,3-tetramine
    • MFCD00008210
    • N'-[2-(3-aminopropylamino)ethyl]propane-1,3-diamine
    • NSC180823
    • CHEMBL259148
    • N,N'-Bis(3-aminopropyl)-1,2-ethanediamine
    • N,N''-ethylenebis-1,3-propanediamine
    • (3-aminopropyl)({2-[(3-aminopropyl)amino]ethyl})amine
    • N,N''-1,2-ethanediylbis-1,3-propanediamine
    • N(1'),N(3)-ethane-1,2-diyldipropane-1,3-diamine
    • 1,2-Bis(3-aminopropylamino)ethane, 96%
    • C8H22N4
    • UNII-0EXW8894XX
    • N,N'-Bis(3-aminopropyl)-1,2-ethylenediamine
    • 1,8,12-Tetraazadodecane
    • 1, N,N''-ethylenebis-
    • SCHEMBL20976
    • BIDD:GT0255
    • 1,5,8, 12-Tetraazadodecane
    • SCHEMBL10874825
    • 1,10-diamino-4,7-diazadecane
    • CHEBI:39476
    • 3,3'-Ethylenediiminodipropylamine
    • 1, N,N''-1,2-ethanediylbis-
    • KAA56326
    • BDBM50376458
    • AKOS015894471
    • CS-W017488
    • N, N'-Bis(3-aminopropyl)ethylenediamine
    • LS-13569
    • DB-040641
    • NS00019760
    • E83024
    • EN300-157336
    • N,N'-Di(3-aminopropyl)-1, 2-ethylenediamine
    • 1, 3-Propanediamine, N,N''-1,2-ethanediylbis-
    • Q27120355
    • 1,2-Bis(3-aminopropylamino)ethane, technical grade, 94%
    • N~1~,N~1'~-(Ethane-1,2-diyl)di(propane-1,3-diamine)
    • N~1~-(2-((3-Aminopropyl)amino)ethyl)-1,3-propanediamine
    • N,N inverted exclamation mark(R)-Bis(3-Aminopropyl)Ethylenediamine
    • 10563-26-5

  • Applications

    N,N'-bis(3-aminopropyl)ethylenediamine (CAS 10563-26-5) is a tetra-amine used primarily as a curing agent for epoxy resins in coatings, adhesives, and composites; it also serves as a crosslinking agent or chain extender in polyurethane and polyamide systems, improving network formation and durability. It is also an intermediate or building block in the synthesis of specialty polymers and resins, and can be used to prepare chelating ligands or metal-chelating resin functionalities. Other potential applications include electronics encapsulation/potting based on epoxy chemistries. The fields involved include industrial manufacturing, coatings/inks, and electronics, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 148.05
    methanol 597.13
    isopropanol 38.61
    water 441.43
    ethyl acetate 16.67
    n-propanol 109.26
    acetone 22.16
    n-butanol 66.88
    acetonitrile 17.55
    DMF 184.39
    toluene 3.58
    isobutanol 48.96
    1,4-dioxane 32.99
    methyl acetate 17.14
    THF 101.53
    2-butanone 16.38
    n-pentanol 30.07
    sec-butanol 29.3
    n-hexane 1.16
    ethylene glycol 368.21
    NMP 315.59
    cyclohexane 3.41
    DMSO 521.91
    n-butyl acetate 18.79
    n-octanol 8.1
    chloroform 54.03
    n-propyl acetate 13.01
    acetic acid 801.81
    dichloromethane 42.73
    cyclohexanone 66.33
    propylene glycol 237.04
    isopropyl acetate 8.25
    DMAc 115.59
    2-ethoxyethanol 115.7
    isopentanol 27.84
    n-heptane 2.74
    ethyl formate 63.5
    1,2-dichloroethane 23.2
    n-hexanol 31.25
    2-methoxyethanol 320.71
    isobutyl acetate 7.81
    tetrachloromethane 20.61
    n-pentyl acetate 9.79
    transcutol 82.09
    n-heptanol 18.38
    ethylbenzene 1.33
    MIBK 5.49
    2-propoxyethanol 112.68
    tert-butanol 24.96
    MTBE 4.62
    2-butoxyethanol 66.88
    propionic acid 235.33
    o-xylene 3.27
    formic acid 1326.09
    diethyl ether 5.88
    m-xylene 2.76
    p-xylene 1.96
    chlorobenzene 11.14
    dimethyl carbonate 16.68
    n-octane 0.9
    formamide 742.28
    cyclopentanone 125.62
    2-pentanone 13.32
    anisole 4.45
    cyclopentyl methyl ether 30.44
    gamma-butyrolactone 242.83
    1-methoxy-2-propanol 119.73
    pyridine 43.06
    3-pentanone 11.68
    furfural 245.58
    n-dodecane 0.47
    diethylene glycol 179.78
    diisopropyl ether 1.62
    tert-amyl alcohol 23.43
    acetylacetone 20.1
    n-hexadecane 0.49
    acetophenone 10.76
    methyl propionate 26.62
    isopentyl acetate 12.01
    trichloroethylene 56.02
    n-nonanol 7.32
    cyclohexanol 49.78
    benzyl alcohol 22.21
    2-ethylhexanol 12.76
    isooctanol 11.15
    dipropyl ether 10.1
    1,2-dichlorobenzene 13.28
    ethyl lactate 33.22
    propylene carbonate 99.85
    n-methylformamide 306.39
    2-pentanol 16.42
    n-pentane 1.53
    1-propoxy-2-propanol 57.46
    1-methoxy-2-propyl acetate 24.5
    2-(2-methoxypropoxy) propanol 23.11
    mesitylene 1.95
    ε-caprolactone 75.91
    p-cymene 3.25
    epichlorohydrin 95.3
    1,1,1-trichloroethane 15.21
    2-aminoethanol 394.91
    morpholine-4-carbaldehyde 191.73
    sulfolane 451.18
    2,2,4-trimethylpentane 1.04
    2-methyltetrahydrofuran 36.48
    n-hexyl acetate 8.89
    isooctane 0.45
    2-(2-butoxyethoxy)ethanol 38.3
    sec-butyl acetate 5.6
    tert-butyl acetate 7.71
    decalin 1.09
    glycerin 515.37
    diglyme 68.67
    acrylic acid 321.05
    isopropyl myristate 2.81
    n-butyric acid 224.22
    acetyl acetate 18.82
    di(2-ethylhexyl) phthalate 10.66
    ethyl propionate 10.94
    nitromethane 320.34
    1,2-diethoxyethane 9.74
    benzonitrile 15.0
    trioctyl phosphate 8.58
    1-bromopropane 7.86
    gamma-valerolactone 201.56
    n-decanol 4.96
    triethyl phosphate 13.4
    4-methyl-2-pentanol 6.36
    propionitrile 20.09
    vinylene carbonate 94.53
    1,1,2-trichlorotrifluoroethane 351.98
    DMS 12.17
    cumene 1.52
    2-octanol 5.56
    2-hexanone 7.75
    octyl acetate 5.23
    limonene 5.13
    1,2-dimethoxyethane 49.84
    ethyl orthosilicate 12.28
    tributyl phosphate 10.45
    diacetone alcohol 26.94
    N,N-dimethylaniline 5.22
    acrylonitrile 40.83
    aniline 27.06
    1,3-propanediol 294.94
    bromobenzene 7.14
    dibromomethane 22.99
    1,1,2,2-tetrachloroethane 55.49
    2-methyl-cyclohexyl acetate 12.06
    tetrabutyl urea 12.08
    diisobutyl methanol 4.74
    2-phenylethanol 20.76
    styrene 2.1
    dioctyl adipate 7.13
    dimethyl sulfate 62.32
    ethyl butyrate 15.78
    methyl lactate 86.73
    butyl lactate 29.16
    diethyl carbonate 10.87
    propanediol butyl ether 51.17
    triethyl orthoformate 16.45
    p-tert-butyltoluene 3.39
    methyl 4-tert-butylbenzoate 16.97
    morpholine 78.97
    tert-butylamine 10.85
    n-dodecanol 3.68
    dimethoxymethane 44.38
    ethylene carbonate 71.35
    cyrene 65.22
    2-ethoxyethyl acetate 13.59
    2-ethylhexyl acetate 9.42
    1,2,4-trichlorobenzene 17.93
    4-methylpyridine 20.07
    dibutyl ether 3.85
    2,6-dimethyl-4-heptanol 4.74
    DEF 46.88
    dimethyl isosorbide 47.79
    tetrachloroethylene 66.82
    eugenol 26.47
    triacetin 17.76
    span 80 34.71
    1,4-butanediol 120.02
    1,1-dichloroethane 11.24
    2-methyl-1-pentanol 15.64
    methyl formate 164.05
    2-methyl-1-butanol 34.55
    n-decane 0.8
    butyronitrile 19.03
    3,7-dimethyl-1-octanol 5.86
    1-chlorooctane 2.51
    1-chlorotetradecane 1.04
    n-nonane 0.8
    undecane 0.58
    tert-butylcyclohexane 0.83
    cyclooctane 1.29
    cyclopentanol 108.05
    tetrahydropyran 24.85
    tert-amyl methyl ether 5.56
    2,5,8-trioxanonane 43.43
    1-hexene 2.56
    2-isopropoxyethanol 39.41
    2,2,2-trifluoroethanol 348.08
    methyl butyrate 19.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction