N,N-Bis(2-hydroxyethyl)hexadecanamide

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  • Identifiers

    CAS number
    7545-24-6

    Molecular formula
    C20H41NO3

    SMILES
    CCCCCCCCCCCCCCCC(=O)N(CCO)CCO

    Safety labels

    Corrosive
    Corrosive

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 42.78%
    Odorless 34.53%
    Oily 33.61%
    Fresh 31.13%
    Fatty 29.76%
    Woody 28.3%
    Sweet 27.83%
    Fishy 26.7%
    Savory 24.34%
    Animal 24.29%

     

    Flavor
    Odorless 36.06%
    Bland 35.99%
    Mild 35.6%
    Fatty 30.78%
    Waxy 30.04%
    Faint 24.93%
    Slightly waxy 22.77%
    Oily 22.46%
    Bay oil 21.79%
    Delicate 21.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.7

    pKa est.
    6.79 (neutral)

    Molecular weight
    343.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    514°C

    Flash point

    • 217.16 ˚C est.

  • Synonyms

    • 7545-24-6
    • N,N-Bis(2-hydroxyethyl)hexadecanamide
    • Palmitamide DEA
    • N,N-Bis(2-hydroxyethyl)palmitamide
    • N,N-Bis(2-hydroxyethyl)hexadecan-1-amide
    • Palmitic diethanolamide
    • Palmitic acid diethanolamide
    • Hexadecanamide, N,N-bis(2-hydroxyethyl)-
    • EINECS 231-427-2
    • Palmitic acid, diethanolamide
    • Diethanolamine palmitic acid amide
    • SZ3923Q89F
    • PALMITYLDIETHANOLAMIDE
    • PALMITOYL DIETHANOLAMIDE
    • N,N-DIETHYLOLPALMITAMIDE
    • DTXSID90880419
    • RefChem:822148
    • PALMITAMIDE DEA [INCI]
    • DTXCID609414
    • C15DEA
    • MFCD28971954
    • UNII-SZ3923Q89F
    • Hexadecanamide,N,N-bis(2-hydroxyethyl)-
    • C15-Coconut diethanolamide
    • SCHEMBL284784
    • SCHEMBL7777849
    • CHEMBL2238330
    • SCHEMBL16829996
    • AKOS037645875
    • AS-64394
    • N,N-BIS(2-HYDROXYETHYL)-PALMITAMIDE
    • NS00013929
    • D81526
    • Q27289474
    • 7545-24-6

  • Applications

    N,N-Bis(2-hydroxyethyl)hexadecanamide is a fatty diethanolamide that primarily acts as a nonionic surfactant and emulsifier. In real‑world applications it is used as a surfactant and emulsifier in cosmetics and personal care (shampoos, body washes) and in household cleaning products; it also serves as a thickener and rheology modifier to control viscosity, and as a foam booster to improve foam properties in cleansing formulations. In industrial manufacturing, it can function as a surface-active dispersant/emulsifier in paints, coatings, and inks to improve dispersion and stability. Additionally, it is commonly evaluated as a synthesis precursor or raw material for other diethanolamide-based surfactants used in specialty cleaners.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 16.93
    methanol 48.05
    isopropanol 16.68
    water 0.24
    ethyl acetate 80.95
    n-propanol 25.29
    acetone 63.91
    n-butanol 26.6
    acetonitrile 33.62
    DMF 167.5
    toluene 26.44
    isobutanol 26.18
    1,4-dioxane 95.26
    methyl acetate 62.9
    THF 259.98
    2-butanone 80.6
    n-pentanol 26.04
    sec-butanol 27.77
    n-hexane 4.06
    ethylene glycol 4.96
    NMP 391.69
    cyclohexane 23.93
    DMSO 321.3
    n-butyl acetate 95.25
    n-octanol 28.44
    chloroform 248.96
    n-propyl acetate 120.75
    acetic acid 80.46
    dichloromethane 268.82
    cyclohexanone 308.24
    propylene glycol 10.88
    isopropyl acetate 86.36
    DMAc 315.34
    2-ethoxyethanol 79.61
    isopentanol 38.44
    n-heptane 4.86
    ethyl formate 61.31
    1,2-dichloroethane 191.32
    n-hexanol 22.0
    2-methoxyethanol 86.16
    isobutyl acetate 74.0
    tetrachloromethane 64.7
    n-pentyl acetate 148.54
    transcutol 310.44
    n-heptanol 30.13
    ethylbenzene 22.01
    MIBK 81.87
    2-propoxyethanol 69.36
    tert-butanol 43.39
    MTBE 50.58
    2-butoxyethanol 98.67
    propionic acid 59.88
    o-xylene 33.25
    formic acid 28.83
    diethyl ether 32.57
    m-xylene 24.0
    p-xylene 34.42
    chlorobenzene 62.07
    dimethyl carbonate 34.34
    n-octane 3.11
    formamide 55.31
    cyclopentanone 296.8
    2-pentanone 81.87
    anisole 50.86
    cyclopentyl methyl ether 117.01
    gamma-butyrolactone 324.98
    1-methoxy-2-propanol 79.38
    pyridine 115.9
    3-pentanone 76.37
    furfural 252.35
    n-dodecane 1.97
    diethylene glycol 42.04
    diisopropyl ether 18.86
    tert-amyl alcohol 50.12
    acetylacetone 133.57
    n-hexadecane 2.35
    acetophenone 95.86
    methyl propionate 72.47
    isopentyl acetate 96.2
    trichloroethylene 314.76
    n-nonanol 28.72
    cyclohexanol 73.41
    benzyl alcohol 48.07
    2-ethylhexanol 27.42
    isooctanol 32.15
    dipropyl ether 42.61
    1,2-dichlorobenzene 88.5
    ethyl lactate 60.57
    propylene carbonate 187.38
    n-methylformamide 68.42
    2-pentanol 21.85
    n-pentane 3.05
    1-propoxy-2-propanol 70.97
    1-methoxy-2-propyl acetate 99.45
    2-(2-methoxypropoxy) propanol 77.84
    mesitylene 20.9
    ε-caprolactone 270.51
    p-cymene 22.7
    epichlorohydrin 273.22
    1,1,1-trichloroethane 179.83
    2-aminoethanol 17.35
    morpholine-4-carbaldehyde 238.81
    sulfolane 592.59
    2,2,4-trimethylpentane 5.19
    2-methyltetrahydrofuran 162.19
    n-hexyl acetate 116.13
    isooctane 2.43
    2-(2-butoxyethoxy)ethanol 107.3
    sec-butyl acetate 82.02
    tert-butyl acetate 112.13
    decalin 9.61
    glycerin 27.32
    diglyme 269.98
    acrylic acid 51.44
    isopropyl myristate 31.67
    n-butyric acid 119.42
    acetyl acetate 73.16
    di(2-ethylhexyl) phthalate 38.89
    ethyl propionate 92.37
    nitromethane 166.02
    1,2-diethoxyethane 98.17
    benzonitrile 67.77
    trioctyl phosphate 29.35
    1-bromopropane 74.25
    gamma-valerolactone 423.04
    n-decanol 17.87
    triethyl phosphate 63.89
    4-methyl-2-pentanol 20.91
    propionitrile 37.24
    vinylene carbonate 151.53
    1,1,2-trichlorotrifluoroethane 251.39
    DMS 73.58
    cumene 19.16
    2-octanol 24.72
    2-hexanone 85.96
    octyl acetate 44.34
    limonene 37.29
    1,2-dimethoxyethane 183.3
    ethyl orthosilicate 60.43
    tributyl phosphate 41.7
    diacetone alcohol 123.91
    N,N-dimethylaniline 44.66
    acrylonitrile 47.51
    aniline 39.21
    1,3-propanediol 30.48
    bromobenzene 66.55
    dibromomethane 159.87
    1,1,2,2-tetrachloroethane 314.44
    2-methyl-cyclohexyl acetate 84.68
    tetrabutyl urea 60.46
    diisobutyl methanol 21.02
    2-phenylethanol 41.62
    styrene 25.93
    dioctyl adipate 68.52
    dimethyl sulfate 102.77
    ethyl butyrate 95.86
    methyl lactate 50.9
    butyl lactate 107.03
    diethyl carbonate 59.96
    propanediol butyl ether 74.6
    triethyl orthoformate 80.74
    p-tert-butyltoluene 21.09
    methyl 4-tert-butylbenzoate 107.13
    morpholine 143.92
    tert-butylamine 25.69
    n-dodecanol 12.21
    dimethoxymethane 74.14
    ethylene carbonate 138.24
    cyrene 113.14
    2-ethoxyethyl acetate 159.98
    2-ethylhexyl acetate 79.97
    1,2,4-trichlorobenzene 106.72
    4-methylpyridine 98.69
    dibutyl ether 49.91
    2,6-dimethyl-4-heptanol 21.02
    DEF 160.99
    dimethyl isosorbide 168.16
    tetrachloroethylene 228.25
    eugenol 90.62
    triacetin 150.59
    span 80 72.15
    1,4-butanediol 15.64
    1,1-dichloroethane 122.24
    2-methyl-1-pentanol 34.38
    methyl formate 50.03
    2-methyl-1-butanol 36.59
    n-decane 4.41
    butyronitrile 42.71
    3,7-dimethyl-1-octanol 29.49
    1-chlorooctane 26.09
    1-chlorotetradecane 7.3
    n-nonane 4.1
    undecane 2.73
    tert-butylcyclohexane 6.67
    cyclooctane 5.36
    cyclopentanol 77.94
    tetrahydropyran 130.85
    tert-amyl methyl ether 55.77
    2,5,8-trioxanonane 145.13
    1-hexene 14.0
    2-isopropoxyethanol 64.04
    2,2,2-trifluoroethanol 56.74
    methyl butyrate 150.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction