Nitrosylsulfuric acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    7782-78-7

    Molecular formula
    HNO5S

    SMILES
    N(=O)OS(=O)(=O)O

    Safety labels

    Oxidizer
    Oxidizer

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 87.07%
    Sulfurous 21.49%
    Pungent 18.62%
    Cooked 16.23%
    Sour 15.16%
    Burnt 14.47%
    Sharp 13.89%
    Savory 13.16%
    Roasted 12.9%
    Clean 12.8%

     

    Flavor
    Bitter 72.97%
    Odorless 36.71%
    Bland 25.03%
    Formyl 20.69%
    Nitrile 20.17%
    Rotten 19.34%
    Mousy 18.52%
    Taco 18.48%
    Bread crust 18.45%
    Very mild 18.13%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.9

    pKa est.
    7.03 (neutral)

    Molecular weight
    127.08 g/mol

    Melting point expt.

    • 73.5 °C

    Flash point

    • 124.5 ˚C est.

  • Synonyms

    • Nitrosylsulfuric acid
    • 7782-78-7
    • nitrosyl sulfate
    • chamber crystals
    • Nitrosylsulphuric acid
    • NITROSOSULFURIC ACID
    • nitrosyl sulfuric acid
    • nitrosulfonic acid
    • nitroso hydrogen sulfate
    • nitrosyl hydrogen sulfate
    • nitro acid sulfite
    • Nitroxylsulfuric acid
    • Sulfuric acid, monoanhydride with nitrous acid
    • UNII-40K942UPM8
    • 40K942UPM8
    • Sulfuric acid monoanhydride with nitrous acid
    • EINECS 231-964-2
    • UN2308
    • DTXSID30889380
    • EC 231-964-2
    • NITROSYLSULFURIC ACID [MI]
    • Sulfuric acid, anhydride with nitrous acid (1:1)
    • nitrosonium bisulfate
    • Nitrosa
    • Nitrose
    • Nitrosil Solfato
    • Nitrosyl sulphate
    • Nitrosyl sulfate ((NO)H(SO4))
    • Nitrosylschwefelsaure
    • Acido Nitrosolfonico
    • nitrososulphuric acid
    • Cristalli di Chamber
    • UN3456
    • Lead chamber crystals
    • nitrosyl-sulfuric acid
    • nitroso hydrogen sulate
    • nitrosyl-sulphuric acid
    • Nitrosyl sulphuric acid
    • NITROSYL BISULFATE
    • Nitrosil Idrogeno Solfato
    • Nitrosyl hydrogen sulphate
    • CHEBI:230452
    • DTXCID701028642
    • NITROSONIUM HYDROGEN SULFATE
    • AKOS025310763
    • NITROSYLSULFURIC ACID (NOHSO4)
    • NS00044438
    • Nitrosylsulfuric acid [UN2308] [Corrosive]
    • Nitrosylsulfuric acid [UN2308] [Corrosive]
    • Q419812

  • Applications

    Nitrosylsulfuric acid is a highly reactive nitrating and nitrosating reagent used in chemical synthesis under strongly acidic conditions. It provides electrophilic nitro- and nitroso- species for introducing nitro and nitroso groups into organic substrates, enabling nitration and nitrosation of aromatic and functionalized compounds. In industry, it is employed to prepare nitroaromatic intermediates that feed the production of dyes and pigments, pharmaceutical precursors, and related specialty chemicals. It also functions as a reagent for polymer and material functionalization, supporting coating and adhesive formulations in industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.26
    methanol 112.54
    isopropanol 37.46
    water 99.28
    ethyl acetate 9.24
    n-propanol 35.37
    acetone 54.72
    n-butanol 26.66
    acetonitrile 24.4
    DMF 486.62
    toluene 2.61
    isobutanol 19.48
    1,4-dioxane 20.43
    methyl acetate 14.75
    THF 67.78
    2-butanone 25.59
    n-pentanol 17.36
    sec-butanol 21.22
    n-hexane 1.05
    ethylene glycol 70.72
    NMP 246.37
    cyclohexane 0.83
    DMSO 625.87
    n-butyl acetate 7.76
    n-octanol 4.65
    chloroform 1.09
    n-propyl acetate 10.44
    acetic acid 33.02
    dichloromethane 2.53
    cyclohexanone 21.12
    propylene glycol 61.45
    isopropyl acetate 7.39
    DMAc 263.03
    2-ethoxyethanol 79.39
    isopentanol 16.99
    n-heptane 1.18
    ethyl formate 20.58
    1,2-dichloroethane 4.39
    n-hexanol 9.5
    2-methoxyethanol 173.48
    isobutyl acetate 3.95
    tetrachloromethane 0.44
    n-pentyl acetate 5.45
    transcutol 47.08
    n-heptanol 6.27
    ethylbenzene 1.57
    MIBK 12.6
    2-propoxyethanol 53.99
    tert-butanol 26.64
    MTBE 5.93
    2-butoxyethanol 28.6
    propionic acid 22.18
    o-xylene 3.09
    formic acid 75.26
    diethyl ether 9.43
    m-xylene 2.62
    p-xylene 1.89
    chlorobenzene 0.92
    dimethyl carbonate 21.2
    n-octane 0.43
    formamide 146.69
    cyclopentanone 46.36
    2-pentanone 22.64
    anisole 6.05
    cyclopentyl methyl ether 16.14
    gamma-butyrolactone 52.43
    1-methoxy-2-propanol 120.23
    pyridine 14.44
    3-pentanone 13.91
    furfural 48.24
    n-dodecane 0.31
    diethylene glycol 72.38
    diisopropyl ether 2.54
    tert-amyl alcohol 16.14
    acetylacetone 22.94
    n-hexadecane 0.34
    acetophenone 10.44
    methyl propionate 19.03
    isopentyl acetate 5.02
    trichloroethylene 3.23
    n-nonanol 4.49
    cyclohexanol 10.91
    benzyl alcohol 10.49
    2-ethylhexanol 4.26
    isooctanol 4.04
    dipropyl ether 8.33
    1,2-dichlorobenzene 0.93
    ethyl lactate 20.76
    propylene carbonate 18.34
    n-methylformamide 169.01
    2-pentanol 13.88
    n-pentane 1.34
    1-propoxy-2-propanol 33.69
    1-methoxy-2-propyl acetate 15.31
    2-(2-methoxypropoxy) propanol 26.3
    mesitylene 2.02
    ε-caprolactone 18.53
    p-cymene 1.64
    epichlorohydrin 28.79
    1,1,1-trichloroethane 1.22
    2-aminoethanol 87.16
    morpholine-4-carbaldehyde 134.52
    sulfolane 125.07
    2,2,4-trimethylpentane 0.37
    2-methyltetrahydrofuran 19.27
    n-hexyl acetate 5.53
    isooctane 0.32
    2-(2-butoxyethoxy)ethanol 33.04
    sec-butyl acetate 4.65
    tert-butyl acetate 7.69
    decalin 0.47
    glycerin 106.4
    diglyme 48.93
    acrylic acid 27.61
    isopropyl myristate 2.9
    n-butyric acid 19.4
    acetyl acetate 4.76
    di(2-ethylhexyl) phthalate 4.58
    ethyl propionate 10.17
    nitromethane 76.56
    1,2-diethoxyethane 8.86
    benzonitrile 6.07
    trioctyl phosphate 4.22
    1-bromopropane 2.58
    gamma-valerolactone 74.97
    n-decanol 3.69
    triethyl phosphate 5.02
    4-methyl-2-pentanol 6.73
    propionitrile 16.26
    vinylene carbonate 15.01
    1,1,2-trichlorotrifluoroethane 31.9
    DMS 6.28
    cumene 1.4
    2-octanol 3.6
    2-hexanone 13.47
    octyl acetate 4.27
    limonene 2.19
    1,2-dimethoxyethane 75.21
    ethyl orthosilicate 4.01
    tributyl phosphate 4.43
    diacetone alcohol 29.19
    N,N-dimethylaniline 9.32
    acrylonitrile 25.74
    aniline 7.67
    1,3-propanediol 75.92
    bromobenzene 0.57
    dibromomethane 1.79
    1,1,2,2-tetrachloroethane 3.69
    2-methyl-cyclohexyl acetate 5.23
    tetrabutyl urea 11.25
    diisobutyl methanol 3.29
    2-phenylethanol 7.82
    styrene 1.49
    dioctyl adipate 5.7
    dimethyl sulfate 47.71
    ethyl butyrate 8.1
    methyl lactate 43.91
    butyl lactate 13.54
    diethyl carbonate 4.76
    propanediol butyl ether 31.33
    triethyl orthoformate 5.81
    p-tert-butyltoluene 1.63
    methyl 4-tert-butylbenzoate 12.12
    morpholine 44.34
    tert-butylamine 10.79
    n-dodecanol 2.87
    dimethoxymethane 103.23
    ethylene carbonate 12.39
    cyrene 40.43
    2-ethoxyethyl acetate 7.73
    2-ethylhexyl acetate 3.58
    1,2,4-trichlorobenzene 1.33
    4-methylpyridine 14.39
    dibutyl ether 3.27
    2,6-dimethyl-4-heptanol 3.29
    DEF 47.77
    dimethyl isosorbide 36.39
    tetrachloroethylene 2.32
    eugenol 18.62
    triacetin 8.3
    span 80 17.82
    1,4-butanediol 35.04
    1,1-dichloroethane 2.04
    2-methyl-1-pentanol 9.63
    methyl formate 84.69
    2-methyl-1-butanol 15.57
    n-decane 0.45
    butyronitrile 14.61
    3,7-dimethyl-1-octanol 3.21
    1-chlorooctane 1.06
    1-chlorotetradecane 0.61
    n-nonane 0.45
    undecane 0.37
    tert-butylcyclohexane 0.38
    cyclooctane 0.51
    cyclopentanol 21.47
    tetrahydropyran 11.8
    tert-amyl methyl ether 6.7
    2,5,8-trioxanonane 41.66
    1-hexene 2.7
    2-isopropoxyethanol 33.85
    2,2,2-trifluoroethanol 23.53
    methyl butyrate 15.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction