N2-(Carboxymethyl)-L-arginine

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  • Identifiers

    CAS number
    18416-86-9

    Molecular formula
    C8H16N4O4

    SMILES
    C(C[C@@H](C(=O)O)NCC(=O)O)CN=C(N)N

    Safety labels

  • Odor profile

    Fragrance
    Odorless 70.75%
    Savory 38.62%
    Meaty 31.96%
    Fishy 30.65%
    Cooling 21.07%
    Sweet 20.92%
    Cooked 19.7%
    Cheesy 15.85%
    Alcoholic 15.16%
    Milky 14.97%

     

    Flavor
    Odorless 64.14%
    Bitter 40.5%
    Mild 34.96%
    Bland 32.1%
    Faint 24.38%
    Yeast 22.36%
    Sweet-like 22.24%
    Very mild 21.65%
    Nitrile 20.26%
    Taco 19.36%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -4.1

    pKa est.
    7.07 (neutral)

    Molecular weight
    232.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    446°C

    Flash point

    • 233.87 ˚C est.

  • Synonyms

    • N2-(Carboxymethyl)-L-arginine
    • 18416-86-9
    • RefChem:365145
    • carboxymethylarginine
    • SCHEMBL933117
    • DTXSID901308086
    • N~2~-(Carboxymethyl)-L-arginine
    • 18416-86-9

  • Applications

    N2-(Carboxymethyl)-L-arginine (CAS 18416-86-9) may serve as an intermediate in pharmaceutical synthesis and peptide chemistry; acts as a building block for arginine-containing polymers and bioactive derivatives; may function as a ligand or chelating agent in coordination chemistry and catalysis; is used as a reagent in biochemical research and polymer technology development; is investigated as a functional monomer for amino-acid–based materials platforms.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.04
    methanol 0.17
    isopropanol 0.02
    water 46.42
    ethyl acetate 0.04
    n-propanol 0.03
    acetone 0.03
    n-butanol 0.03
    acetonitrile 0.03
    DMF 3.3
    toluene 0.06
    isobutanol 0.03
    1,4-dioxane 0.04
    methyl acetate 0.03
    THF 0.09
    2-butanone 0.04
    n-pentanol 0.03
    sec-butanol 0.03
    n-hexane 0.06
    ethylene glycol 0.87
    NMP 13.5
    cyclohexane 0.03
    DMSO 12.19
    n-butyl acetate 0.05
    n-octanol 0.02
    chloroform 0.03
    n-propyl acetate 0.03
    acetic acid 0.74
    dichloromethane 0.04
    cyclohexanone 0.2
    propylene glycol 0.47
    isopropyl acetate 0.04
    DMAc 5.2
    2-ethoxyethanol 0.23
    isopentanol 0.03
    n-heptane 0.06
    ethyl formate 0.07
    1,2-dichloroethane 0.04
    n-hexanol 0.05
    2-methoxyethanol 0.61
    isobutyl acetate 0.02
    tetrachloromethane 0.02
    n-pentyl acetate 0.03
    transcutol 0.5
    n-heptanol 0.05
    ethylbenzene 0.05
    MIBK 0.05
    2-propoxyethanol 0.42
    tert-butanol 0.04
    MTBE 0.02
    2-butoxyethanol 0.22
    propionic acid 0.24
    o-xylene 0.13
    formic acid 11.64
    diethyl ether 0.02
    m-xylene 0.09
    p-xylene 0.07
    chlorobenzene 0.02
    dimethyl carbonate 0.23
    n-octane 0.02
    formamide 4.84
    cyclopentanone 0.24
    2-pentanone 0.05
    anisole 0.04
    cyclopentyl methyl ether 0.17
    gamma-butyrolactone 0.53
    1-methoxy-2-propanol 0.49
    pyridine 0.11
    3-pentanone 0.09
    furfural 1.32
    n-dodecane 0.01
    diethylene glycol 1.32
    diisopropyl ether 0.02
    tert-amyl alcohol 0.06
    acetylacetone 0.13
    n-hexadecane 0.01
    acetophenone 0.13
    methyl propionate 0.13
    isopentyl acetate 0.05
    trichloroethylene 0.06
    n-nonanol 0.03
    cyclohexanol 0.1
    benzyl alcohol 0.09
    2-ethylhexanol 0.05
    isooctanol 0.04
    dipropyl ether 0.1
    1,2-dichlorobenzene 0.04
    ethyl lactate 0.24
    propylene carbonate 0.33
    n-methylformamide 1.03
    2-pentanol 0.03
    n-pentane 0.02
    1-propoxy-2-propanol 0.3
    1-methoxy-2-propyl acetate 0.2
    2-(2-methoxypropoxy) propanol 0.41
    mesitylene 0.08
    ε-caprolactone 0.26
    p-cymene 0.06
    epichlorohydrin 0.11
    1,1,1-trichloroethane 0.02
    2-aminoethanol 0.47
    morpholine-4-carbaldehyde 2.72
    sulfolane 6.21
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.05
    n-hexyl acetate 0.03
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 0.34
    sec-butyl acetate 0.03
    tert-butyl acetate 0.06
    decalin 0.02
    glycerin 5.13
    diglyme 0.57
    acrylic acid 0.7
    isopropyl myristate 0.02
    n-butyric acid 0.19
    acetyl acetate 0.05
    di(2-ethylhexyl) phthalate 0.06
    ethyl propionate 0.07
    nitromethane 0.58
    1,2-diethoxyethane 0.05
    benzonitrile 0.05
    trioctyl phosphate 0.04
    1-bromopropane 0.02
    gamma-valerolactone 0.85
    n-decanol 0.02
    triethyl phosphate 0.14
    4-methyl-2-pentanol 0.03
    propionitrile 0.03
    vinylene carbonate 0.33
    1,1,2-trichlorotrifluoroethane 1.71
    DMS 0.11
    cumene 0.05
    2-octanol 0.03
    2-hexanone 0.03
    octyl acetate 0.02
    limonene 0.07
    1,2-dimethoxyethane 0.23
    ethyl orthosilicate 0.12
    tributyl phosphate 0.06
    diacetone alcohol 0.31
    N,N-dimethylaniline 0.17
    acrylonitrile 0.09
    aniline 0.12
    1,3-propanediol 0.23
    bromobenzene 0.02
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.08
    2-methyl-cyclohexyl acetate 0.08
    tetrabutyl urea 0.14
    diisobutyl methanol 0.05
    2-phenylethanol 0.09
    styrene 0.04
    dioctyl adipate 0.03
    dimethyl sulfate 1.74
    ethyl butyrate 0.08
    methyl lactate 0.95
    butyl lactate 0.18
    diethyl carbonate 0.05
    propanediol butyl ether 0.3
    triethyl orthoformate 0.12
    p-tert-butyltoluene 0.06
    methyl 4-tert-butylbenzoate 0.28
    morpholine 0.09
    tert-butylamine 0.03
    n-dodecanol 0.02
    dimethoxymethane 0.38
    ethylene carbonate 0.18
    cyrene 1.3
    2-ethoxyethyl acetate 0.05
    2-ethylhexyl acetate 0.04
    1,2,4-trichlorobenzene 0.05
    4-methylpyridine 0.12
    dibutyl ether 0.02
    2,6-dimethyl-4-heptanol 0.05
    DEF 0.41
    dimethyl isosorbide 0.9
    tetrachloroethylene 0.1
    eugenol 0.36
    triacetin 0.12
    span 80 0.3
    1,4-butanediol 0.13
    1,1-dichloroethane 0.01
    2-methyl-1-pentanol 0.03
    methyl formate 0.54
    2-methyl-1-butanol 0.04
    n-decane 0.01
    butyronitrile 0.03
    3,7-dimethyl-1-octanol 0.02
    1-chlorooctane 0.01
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.03
    cyclopentanol 0.1
    tetrahydropyran 0.03
    tert-amyl methyl ether 0.04
    2,5,8-trioxanonane 0.6
    1-hexene 0.05
    2-isopropoxyethanol 0.11
    2,2,2-trifluoroethanol 1.2
    methyl butyrate 0.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
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Rinse-off products applied to the hair with some hand contact
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Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
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Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction