N-Vanillyldecanamide

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  • Identifiers

    CAS number
    31078-36-1

    Molecular formula
    C18H29NO3

    SMILES
    CCCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Spicy 39.38%
    Savory 38.55%
    Odorless 36.11%
    Meaty 36.05%
    Cooling 32.01%
    Herbal 30.04%
    Animal 25.3%
    Burnt 23.76%
    Mint 22.9%
    Pungent 22.65%

     

    Flavor
    Herbal 38.59%
    Odorless 38.1%
    Bland 36.27%
    Mild 33.46%
    Woody 24.99%
    Warm 22.33%
    Faint 22.21%
    Spicy 21.16%
    Lovage 20.98%
    Parsley 20.76%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.7

    pKa est.
    9.69 (weak base)

    Molecular weight
    307.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    467°C

    Flash point

    • 182.72 ˚C est.

  • Synonyms

    • n-vanillyldecanamide
    • 31078-36-1
    • Decylic acid vanillylamide
    • Decanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-
    • BRN 2946587
    • N-[(4-hydroxy-3-methoxyphenyl)methyl]decanamide
    • UNII-18EB43C97X
    • N-((4-Hydroxy-3-methoxyphenyl)methyl)decanamide
    • Decanamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-
    • 18EB43C97X
    • VANILLYL N-DECOYLAMIDE
    • DECANAMIDE, N-VANILLYL-
    • CAPRIC ACID VANILLYLAMIDE
    • DTXSID00185028
    • RefChem:43512
    • DTXCID10107519
    • DECANYLVANILLYLAMIDE (CONSTITUENT OF CAPSICUM)
    • n-(4-hydroxy-3-methoxybenzyl)decanamide
    • CHEMBL86708
    • MFCD01233545
    • N-Vanillyldecanamide; Vanillyl N-decoylamide
    • N-[(4-Hydroxy-3-methoxyphenyl)methyl]-decanamide (N-Vanillyldecanamide)
    • orb1297401
    • SCHEMBL1155582
    • SCHEMBL29371389
    • GBA07836
    • HY-N5099
    • BDBM50388087
    • AKOS027327162
    • EBC-617337
    • N-(4-hydroxy-3-methoxybenzyl)decamide
    • BS-49204
    • SY231752
    • DB-321304
    • CS-0032363
    • N-[(4-hydroxy-3-methoxy-phenyl)methyl]decanamide
    • Q27252000
    • DECANYLVANILLYLAMIDE (CONSTITUENT OF CAPSICUM) [DSC]
    • N-[(4-Hydroxy-3-methoxyphenyl)methyl]-decanamide; N-Vanillyldecanamide
    • 31078-36-1

  • Applications

    N-Vanillyldecanamide (CAS 31078-36-1) is primarily used in fragrance chemistry as an odorant and fragrance ingredient, contributing vanilla-like notes and often functioning as a fixative to extend scent longevity in perfumery and cosmetics/personal care formulations; it is also used as an intermediate in fragrance synthesis. Additionally, it is considered for use in household products and cleaners as a fragrance additive, and in polymer/plastic formulations it can serve as a processing aid or odorant modifier.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 795.69
    methanol 1732.48
    isopropanol 312.89
    water 0.2
    ethyl acetate 771.73
    n-propanol 369.27
    acetone 1569.76
    n-butanol 238.24
    acetonitrile 340.69
    DMF 691.36
    toluene 44.2
    isobutanol 181.92
    1,4-dioxane 521.32
    methyl acetate 482.04
    THF 813.94
    2-butanone 523.77
    n-pentanol 128.16
    sec-butanol 171.61
    n-hexane 0.52
    ethylene glycol 57.77
    NMP 304.47
    cyclohexane 3.83
    DMSO 2252.41
    n-butyl acetate 169.84
    n-octanol 36.96
    chloroform 421.3
    n-propyl acetate 251.04
    acetic acid 688.26
    dichloromethane 559.92
    cyclohexanone 598.94
    propylene glycol 127.06
    isopropyl acetate 323.83
    DMAc 669.34
    2-ethoxyethanol 424.15
    isopentanol 173.15
    n-heptane 0.89
    ethyl formate 298.65
    1,2-dichloroethane 488.33
    n-hexanol 74.55
    2-methoxyethanol 983.49
    isobutyl acetate 137.42
    tetrachloromethane 40.38
    n-pentyl acetate 127.06
    transcutol 886.22
    n-heptanol 44.71
    ethylbenzene 23.91
    MIBK 191.97
    2-propoxyethanol 257.8
    tert-butanol 373.67
    MTBE 246.09
    2-butoxyethanol 153.97
    propionic acid 299.6
    o-xylene 36.33
    formic acid 218.81
    diethyl ether 151.76
    m-xylene 34.21
    p-xylene 36.97
    chlorobenzene 105.96
    dimethyl carbonate 128.06
    n-octane 1.21
    formamide 483.46
    cyclopentanone 745.05
    2-pentanone 462.89
    anisole 92.83
    cyclopentyl methyl ether 174.4
    gamma-butyrolactone 730.97
    1-methoxy-2-propanol 466.35
    pyridine 275.31
    3-pentanone 211.65
    furfural 437.47
    n-dodecane 1.86
    diethylene glycol 233.37
    diisopropyl ether 27.69
    tert-amyl alcohol 210.92
    acetylacetone 664.55
    n-hexadecane 2.11
    acetophenone 128.74
    methyl propionate 357.44
    isopentyl acetate 154.43
    trichloroethylene 699.0
    n-nonanol 36.62
    cyclohexanol 165.36
    benzyl alcohol 112.86
    2-ethylhexanol 38.0
    isooctanol 41.06
    dipropyl ether 33.86
    1,2-dichlorobenzene 105.87
    ethyl lactate 99.57
    propylene carbonate 313.73
    n-methylformamide 444.25
    2-pentanol 94.93
    n-pentane 0.5
    1-propoxy-2-propanol 152.97
    1-methoxy-2-propyl acetate 208.01
    2-(2-methoxypropoxy) propanol 123.9
    mesitylene 22.85
    ε-caprolactone 446.02
    p-cymene 18.61
    epichlorohydrin 764.11
    1,1,1-trichloroethane 261.3
    2-aminoethanol 198.64
    morpholine-4-carbaldehyde 382.98
    sulfolane 739.71
    2,2,4-trimethylpentane 2.56
    2-methyltetrahydrofuran 322.9
    n-hexyl acetate 125.93
    isooctane 1.72
    2-(2-butoxyethoxy)ethanol 198.31
    sec-butyl acetate 144.52
    tert-butyl acetate 294.1
    decalin 3.56
    glycerin 173.08
    diglyme 452.04
    acrylic acid 209.46
    isopropyl myristate 39.38
    n-butyric acid 587.52
    acetyl acetate 327.51
    di(2-ethylhexyl) phthalate 49.58
    ethyl propionate 174.45
    nitromethane 1455.68
    1,2-diethoxyethane 205.59
    benzonitrile 123.11
    trioctyl phosphate 34.72
    1-bromopropane 101.11
    gamma-valerolactone 883.2
    n-decanol 26.29
    triethyl phosphate 57.06
    4-methyl-2-pentanol 54.13
    propionitrile 165.58
    vinylene carbonate 248.79
    1,1,2-trichlorotrifluoroethane 445.14
    DMS 131.57
    cumene 19.2
    2-octanol 30.02
    2-hexanone 177.73
    octyl acetate 54.2
    limonene 26.34
    1,2-dimethoxyethane 535.73
    ethyl orthosilicate 53.75
    tributyl phosphate 45.78
    diacetone alcohol 319.83
    N,N-dimethylaniline 55.01
    acrylonitrile 234.45
    aniline 106.18
    1,3-propanediol 410.94
    bromobenzene 94.77
    dibromomethane 259.21
    1,1,2,2-tetrachloroethane 555.67
    2-methyl-cyclohexyl acetate 84.81
    tetrabutyl urea 60.17
    diisobutyl methanol 28.03
    2-phenylethanol 89.33
    styrene 33.12
    dioctyl adipate 74.09
    dimethyl sulfate 223.02
    ethyl butyrate 115.1
    methyl lactate 155.43
    butyl lactate 115.48
    diethyl carbonate 81.19
    propanediol butyl ether 139.24
    triethyl orthoformate 76.35
    p-tert-butyltoluene 18.69
    methyl 4-tert-butylbenzoate 120.37
    morpholine 665.12
    tert-butylamine 92.04
    n-dodecanol 19.92
    dimethoxymethane 503.36
    ethylene carbonate 251.49
    cyrene 132.6
    2-ethoxyethyl acetate 232.08
    2-ethylhexyl acetate 98.73
    1,2,4-trichlorobenzene 125.94
    4-methylpyridine 206.03
    dibutyl ether 46.9
    2,6-dimethyl-4-heptanol 28.03
    DEF 333.35
    dimethyl isosorbide 216.65
    tetrachloroethylene 315.29
    eugenol 117.95
    triacetin 170.27
    span 80 104.43
    1,4-butanediol 111.94
    1,1-dichloroethane 330.76
    2-methyl-1-pentanol 106.54
    methyl formate 330.93
    2-methyl-1-butanol 138.69
    n-decane 2.78
    butyronitrile 190.01
    3,7-dimethyl-1-octanol 42.12
    1-chlorooctane 20.76
    1-chlorotetradecane 8.18
    n-nonane 2.13
    undecane 2.18
    tert-butylcyclohexane 3.31
    cyclooctane 1.03
    cyclopentanol 169.11
    tetrahydropyran 395.67
    tert-amyl methyl ether 115.64
    2,5,8-trioxanonane 258.13
    1-hexene 6.84
    2-isopropoxyethanol 224.88
    2,2,2-trifluoroethanol 184.66
    methyl butyrate 273.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction