N-Stearoylethanolamine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    111-57-9

    Molecular formula
    C20H41NO2

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)NCCO

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 49.27%
    Fatty 40.1%
    Odorless 33.2%
    Meaty 31.18%
    Savory 30.91%
    Oily 30.26%
    Fishy 30.07%
    Animal 25.02%
    Fresh 22.81%
    Citrus 22.2%

     

    Flavor
    Fatty 40.83%
    Mild 36.13%
    Bland 35.79%
    Waxy 35.59%
    Odorless 33.38%
    Faint 29.56%
    Fat 26.58%
    Slightly waxy 24.22%
    Oily 24.2%
    Bay oil 22.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.3

    pKa est.
    7.66 (neutral)

    Molecular weight
    327.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    446°C

    Melting point expt.

    • 98.5 °C

    Flash point

    • 208.51 ˚C est.

  • Synonyms

    • N-(2-Hydroxyethyl)octadecanamide
    • 111-57-9
    • N-stearoylethanolamine
    • Stearic ethanolamide
    • N-(Hydroxyethyl)stearamide
    • OCTADECANAMIDE, N-(2-HYDROXYETHYL)-
    • Monoethanolamine stearic acid amide
    • 03XV449Q24
    • DTXSID9042178
    • RefChem:825493
    • DTXCID7022178
    • Stearoyl ethanolamide
    • Stearoylethanolamide
    • N-(2-Hydroxyethyl)stearamide
    • Stearamide MEA
    • Stearic monoethanolamide
    • Stearic acid monoethanolamide
    • Stearamyl
    • Stearoyl-ethanolamine
    • Cycloamide SM
    • Comperlan HS
    • Stearoylmonoethanolamide
    • Stearoylethanolamine
    • Stearic ethylolamide
    • Marlamid M 18
    • Ceramid
    • Clindrol 200-MS
    • Loramine S 280
    • Stearic monoethanolamine
    • Stearoyl-EA
    • Stearoyl monoethanolamide
    • N-(octadecanoyl)ethanolamine
    • NSC 3377
    • N-(Octadecanoyl)-ethanolamine
    • CHEMBL171447
    • NSC-3377
    • MFCD00045971
    • 8038-89-9
    • Mackamide SMA
    • Monamid S
    • UNII-03XV449Q24
    • Amidex SME
    • Witcamide 70
    • EINECS 203-883-2
    • Alkamide S-280
    • INCROMIDE SMEA
    • Rewomid S 280
    • 1:1 Stearamide MEA
    • octadecanoyl ethanolamide
    • N-octadecanoylethanolamine
    • Stearic Acid Ethanolamide
    • N-octadecanoyl ethanolamine
    • Stearamide-MEA (1:1)
    • EC 203-883-2
    • N-(otadecanoyl)-ethanolamine
    • SCHEMBL50178
    • GTPL3621
    • orb1707816
    • N-(2-hydroxyethyl)stearoylamide
    • CHEBI:85299
    • NSC3377
    • STEARAMIDE MONOETHANOLAMINE
    • Stearamide, N-(2-hydroxyethyl)-
    • HMS3649H17
    • N-(2-Hydroxyethyl)-octadecanamide
    • NAE 18:0
    • NSC52619
    • BDBM50074620
    • EBC-12042
    • LMFA08040051
    • NAE(18:0)
    • NSC-52619
    • STL454871
    • AKOS002676465
    • FS171406
    • MS-24898
    • SEA
    • Octadecanoic acid (2-hydroxy-ethyl)-amide
    • DB-040991
    • HY-113015
    • Stearoyl ethanolamide, >=98%, crystalline
    • CS-0059359
    • NS00003181
    • G12117
    • EN300-18537220
    • SR-01000946662
    • SR-01000946662-1
    • Q15427850
    • Z3222444503
    • 111-57-9

  • Applications

    N-Stearoylethanolamine (CAS 111-57-9) is commonly used as a nonionic surfactant and emulsifier in cosmetics and personal care, helping to stabilize emulsions and improve skin feel in products such as creams, shampoos, and cleansers. It also serves as an active ingredient in household cleaning formulations, enhancing detergency and dispersion in aqueous systems. In the polymers and plastics sector, it can act as a processing aid, lubricant, or slip agent and as a stabilizing/dispersing additive in formulations. In coatings and inks, it is employed as a dispersant and lubricant to improve leveling and film formation. Additionally, it may function as an intermediate in the synthesis of other N-acyl ethanolamines and related specialty chemicals used as additives in industrial formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.82
    methanol 12.11
    isopropanol 6.54
    water 0.04
    ethyl acetate 36.44
    n-propanol 8.67
    acetone 24.11
    n-butanol 11.29
    acetonitrile 9.11
    DMF 70.22
    toluene 12.61
    isobutanol 10.11
    1,4-dioxane 44.65
    methyl acetate 25.27
    THF 168.88
    2-butanone 36.83
    n-pentanol 12.87
    sec-butanol 11.37
    n-hexane 3.93
    ethylene glycol 1.24
    NMP 217.57
    cyclohexane 17.0
    DMSO 128.98
    n-butyl acetate 66.9
    n-octanol 22.59
    chloroform 141.04
    n-propyl acetate 73.94
    acetic acid 24.06
    dichloromethane 130.82
    cyclohexanone 171.69
    propylene glycol 3.94
    isopropyl acetate 48.19
    DMAc 163.42
    2-ethoxyethanol 37.0
    isopentanol 18.91
    n-heptane 5.6
    ethyl formate 23.83
    1,2-dichloroethane 87.62
    n-hexanol 13.88
    2-methoxyethanol 34.71
    isobutyl acetate 52.55
    tetrachloromethane 35.61
    n-pentyl acetate 119.29
    transcutol 254.58
    n-heptanol 20.94
    ethylbenzene 14.64
    MIBK 56.12
    2-propoxyethanol 40.98
    tert-butanol 21.76
    MTBE 32.52
    2-butoxyethanol 67.44
    propionic acid 21.42
    o-xylene 18.25
    formic acid 6.59
    diethyl ether 16.79
    m-xylene 13.87
    p-xylene 22.8
    chlorobenzene 32.48
    dimethyl carbonate 14.71
    n-octane 3.28
    formamide 12.4
    cyclopentanone 170.54
    2-pentanone 42.24
    anisole 34.26
    cyclopentyl methyl ether 77.46
    gamma-butyrolactone 162.69
    1-methoxy-2-propanol 41.5
    pyridine 53.14
    3-pentanone 39.03
    furfural 127.05
    n-dodecane 2.02
    diethylene glycol 18.68
    diisopropyl ether 13.96
    tert-amyl alcohol 28.11
    acetylacetone 71.93
    n-hexadecane 2.42
    acetophenone 63.91
    methyl propionate 31.12
    isopentyl acetate 74.6
    trichloroethylene 158.47
    n-nonanol 23.91
    cyclohexanol 35.15
    benzyl alcohol 24.73
    2-ethylhexanol 20.52
    isooctanol 24.58
    dipropyl ether 39.56
    1,2-dichlorobenzene 52.21
    ethyl lactate 36.17
    propylene carbonate 100.75
    n-methylformamide 21.89
    2-pentanol 11.22
    n-pentane 2.31
    1-propoxy-2-propanol 52.11
    1-methoxy-2-propyl acetate 73.19
    2-(2-methoxypropoxy) propanol 67.33
    mesitylene 14.26
    ε-caprolactone 149.06
    p-cymene 17.93
    epichlorohydrin 139.0
    1,1,1-trichloroethane 99.72
    2-aminoethanol 5.21
    morpholine-4-carbaldehyde 130.12
    sulfolane 363.08
    2,2,4-trimethylpentane 4.6
    2-methyltetrahydrofuran 101.39
    n-hexyl acetate 98.49
    isooctane 2.44
    2-(2-butoxyethoxy)ethanol 87.82
    sec-butyl acetate 59.03
    tert-butyl acetate 83.15
    decalin 8.62
    glycerin 10.28
    diglyme 210.67
    acrylic acid 17.24
    isopropyl myristate 30.45
    n-butyric acid 50.04
    acetyl acetate 33.21
    di(2-ethylhexyl) phthalate 30.53
    ethyl propionate 58.41
    nitromethane 52.95
    1,2-diethoxyethane 81.29
    benzonitrile 34.17
    trioctyl phosphate 23.01
    1-bromopropane 43.23
    gamma-valerolactone 227.77
    n-decanol 14.86
    triethyl phosphate 52.89
    4-methyl-2-pentanol 13.44
    propionitrile 13.6
    vinylene carbonate 70.46
    1,1,2-trichlorotrifluoroethane 130.94
    DMS 46.63
    cumene 14.51
    2-octanol 19.61
    2-hexanone 60.75
    octyl acetate 38.64
    limonene 30.89
    1,2-dimethoxyethane 113.28
    ethyl orthosilicate 52.98
    tributyl phosphate 32.94
    diacetone alcohol 82.34
    N,N-dimethylaniline 33.56
    acrylonitrile 15.47
    aniline 17.55
    1,3-propanediol 10.73
    bromobenzene 38.41
    dibromomethane 81.83
    1,1,2,2-tetrachloroethane 180.49
    2-methyl-cyclohexyl acetate 76.33
    tetrabutyl urea 51.83
    diisobutyl methanol 19.56
    2-phenylethanol 25.61
    styrene 16.07
    dioctyl adipate 60.38
    dimethyl sulfate 50.16
    ethyl butyrate 77.58
    methyl lactate 24.17
    butyl lactate 78.3
    diethyl carbonate 43.03
    propanediol butyl ether 53.8
    triethyl orthoformate 72.93
    p-tert-butyltoluene 17.75
    methyl 4-tert-butylbenzoate 89.44
    morpholine 69.35
    tert-butylamine 14.85
    n-dodecanol 10.33
    dimethoxymethane 36.12
    ethylene carbonate 64.84
    cyrene 80.8
    2-ethoxyethyl acetate 114.9
    2-ethylhexyl acetate 64.75
    1,2,4-trichlorobenzene 65.63
    4-methylpyridine 49.22
    dibutyl ether 53.04
    2,6-dimethyl-4-heptanol 19.56
    DEF 81.66
    dimethyl isosorbide 152.22
    tetrachloroethylene 116.41
    eugenol 72.02
    triacetin 120.2
    span 80 61.87
    1,4-butanediol 5.89
    1,1-dichloroethane 60.23
    2-methyl-1-pentanol 20.19
    methyl formate 16.19
    2-methyl-1-butanol 17.27
    n-decane 4.77
    butyronitrile 18.52
    3,7-dimethyl-1-octanol 25.64
    1-chlorooctane 24.7
    1-chlorotetradecane 6.93
    n-nonane 4.5
    undecane 2.85
    tert-butylcyclohexane 6.7
    cyclooctane 4.56
    cyclopentanol 37.22
    tetrahydropyran 71.18
    tert-amyl methyl ether 38.68
    2,5,8-trioxanonane 121.38
    1-hexene 10.57
    2-isopropoxyethanol 35.7
    2,2,2-trifluoroethanol 16.96
    methyl butyrate 93.73

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction