N-Oleoylglycine

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  • Identifiers

    CAS number
    2601-90-3

    Molecular formula
    C20H37NO3

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)NCC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 49.83%
    Waxy 42.95%
    Meaty 34.82%
    Savory 32.97%
    Oily 31.88%
    Odorless 31.66%
    Citrus 25.12%
    Milky 24.91%
    Fishy 22.26%
    Herbal 22.15%

     

    Flavor
    Fatty 38.11%
    Faint 31.53%
    Odorless 31.24%
    Mild 29.72%
    Bland 29.45%
    Waxy 28.5%
    Slightly waxy 22.94%
    Fat 22.17%
    Bay oil 21.61%
    Oily 21.3%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.6

    pKa est.
    7.09 (neutral)

    Molecular weight
    339.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    358°C

    Flash point

    • 236.93 ˚C est.

  • Synonyms

    • N-oleoylglycine
    • 2601-90-3
    • 2-[[(Z)-octadec-9-enoyl]amino]acetic acid
    • EMA-1
    • N-(9Z-octadecenoyl)-glycine
    • (Z)-N-(1-Oxo-9-octadecenyl)glycine
    • CHEBI:73723
    • DTXSID201317121
    • 728944BZ3B
    • 2-(((Z)-octadec-9-enoyl)amino)acetic acid
    • RefChem:927301
    • DTXCID001746938
    • 220-009-5
    • N-oleoyl glycine
    • 2-Oleamidoacetic acid
    • oleoyl glycine
    • 2-[(9Z)-octadec-9-enamido]acetic acid
    • N-[(9Z)-octadec-9-enoyl]glycine
    • oleoylglycine
    • Glycine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-
    • N-(9Z-Octadecenoyl)glycine
    • EINECS 220-009-5
    • 2-Oleamidoaceticacid
    • NO-Gly
    • N-oleoylglycine, powder
    • acylglycine 18:1(9Z)
    • N-Oleoylglycine, >=98%
    • CHEMBL226118
    • orb1308785
    • SCHEMBL1104998
    • HMS3649J07
    • BDBM50537018
    • EX-A10764
    • LMFA08020082
    • MFCD01320532
    • AKOS027320432
    • 2-(Octadec-9-enoylamino)ethanoic acid
    • EBC-615630
    • N-(1-Oxo-9-octadecenyl)-(Z)-glycine
    • [(9Z)-octadec-9-enoylamino]acetic acid
    • N-[(9E)-9-OCTADECENOYL]GLYCINE
    • NCGC00161200-02
    • AS-65265
    • DB-216835
    • HY-113204
    • CS-0059311
    • N-[(9Z)-1-Oxo-9-octadecen-1-yl]glycine
    • NS00045512
    • Glycine, N-(1-oxo-9-octadecenyl)-, (Z)-
    • E75903
    • SR-01000946664
    • SR-01000946664-1
    • Q27144069
    • 2601-90-3

  • Applications

    N-Oleoylglycine (CAS 2601-90-3) is an amide of oleic acid and glycine; in industrial and research contexts it is primarily used as an intermediate for the synthesis of N-acylglycines and related lipid-like compounds. Its amphiphilic character makes it a potential surfactant or additive for polymer, coating, and personal care formulations in development. It is also used as an analytical standard or reference material in lipidomics and related biochemical analyses. Moreover, it is often explored as a building block or model compound for lipid signaling-related studies in pharmaceutical and biological research. Use is, of course, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 16.28
    methanol 24.77
    isopropanol 12.83
    water 0.03
    ethyl acetate 13.91
    n-propanol 13.79
    acetone 22.88
    n-butanol 13.12
    acetonitrile 4.38
    DMF 65.76
    toluene 6.74
    isobutanol 10.62
    1,4-dioxane 26.51
    methyl acetate 13.44
    THF 102.1
    2-butanone 24.99
    n-pentanol 16.95
    sec-butanol 14.57
    n-hexane 1.72
    ethylene glycol 1.63
    NMP 116.01
    cyclohexane 2.72
    DMSO 133.27
    n-butyl acetate 23.82
    n-octanol 11.94
    chloroform 36.71
    n-propyl acetate 28.2
    acetic acid 17.95
    dichloromethane 38.33
    cyclohexanone 67.29
    propylene glycol 5.91
    isopropyl acetate 18.94
    DMAc 183.6
    2-ethoxyethanol 46.27
    isopentanol 17.67
    n-heptane 1.19
    ethyl formate 10.55
    1,2-dichloroethane 32.25
    n-hexanol 12.01
    2-methoxyethanol 40.75
    isobutyl acetate 22.27
    tetrachloromethane 7.14
    n-pentyl acetate 31.87
    transcutol 227.93
    n-heptanol 11.69
    ethylbenzene 8.41
    MIBK 26.74
    2-propoxyethanol 40.8
    tert-butanol 24.81
    MTBE 25.41
    2-butoxyethanol 42.05
    propionic acid 13.11
    o-xylene 9.52
    formic acid 7.16
    diethyl ether 10.64
    m-xylene 7.62
    p-xylene 11.28
    chlorobenzene 9.93
    dimethyl carbonate 8.07
    n-octane 0.88
    formamide 12.86
    cyclopentanone 69.59
    2-pentanone 22.61
    anisole 20.07
    cyclopentyl methyl ether 33.27
    gamma-butyrolactone 55.63
    1-methoxy-2-propanol 44.1
    pyridine 24.6
    3-pentanone 18.79
    furfural 46.89
    n-dodecane 0.71
    diethylene glycol 20.83
    diisopropyl ether 6.19
    tert-amyl alcohol 27.8
    acetylacetone 37.39
    n-hexadecane 0.81
    acetophenone 30.89
    methyl propionate 14.84
    isopentyl acetate 30.47
    trichloroethylene 51.98
    n-nonanol 12.6
    cyclohexanol 18.47
    benzyl alcohol 17.55
    2-ethylhexanol 11.3
    isooctanol 12.7
    dipropyl ether 12.52
    1,2-dichlorobenzene 14.27
    ethyl lactate 18.83
    propylene carbonate 31.73
    n-methylformamide 15.85
    2-pentanol 9.96
    n-pentane 0.92
    1-propoxy-2-propanol 36.79
    1-methoxy-2-propyl acetate 37.28
    2-(2-methoxypropoxy) propanol 50.91
    mesitylene 6.61
    ε-caprolactone 57.35
    p-cymene 7.09
    epichlorohydrin 64.18
    1,1,1-trichloroethane 25.57
    2-aminoethanol 7.25
    morpholine-4-carbaldehyde 77.02
    sulfolane 139.09
    2,2,4-trimethylpentane 2.07
    2-methyltetrahydrofuran 51.72
    n-hexyl acetate 36.53
    isooctane 1.12
    2-(2-butoxyethoxy)ethanol 70.62
    sec-butyl acetate 24.07
    tert-butyl acetate 37.31
    decalin 3.22
    glycerin 11.87
    diglyme 128.23
    acrylic acid 9.34
    isopropyl myristate 12.82
    n-butyric acid 25.16
    acetyl acetate 12.21
    di(2-ethylhexyl) phthalate 16.09
    ethyl propionate 20.05
    nitromethane 29.45
    1,2-diethoxyethane 45.99
    benzonitrile 13.74
    trioctyl phosphate 10.64
    1-bromopropane 14.76
    gamma-valerolactone 107.29
    n-decanol 8.33
    triethyl phosphate 18.31
    4-methyl-2-pentanol 10.57
    propionitrile 6.14
    vinylene carbonate 21.07
    1,1,2-trichlorotrifluoroethane 62.8
    DMS 19.95
    cumene 8.23
    2-octanol 9.26
    2-hexanone 34.25
    octyl acetate 16.21
    limonene 10.67
    1,2-dimethoxyethane 85.63
    ethyl orthosilicate 20.66
    tributyl phosphate 14.23
    diacetone alcohol 53.08
    N,N-dimethylaniline 22.14
    acrylonitrile 7.06
    aniline 10.21
    1,3-propanediol 14.0
    bromobenzene 10.3
    dibromomethane 23.05
    1,1,2,2-tetrachloroethane 62.06
    2-methyl-cyclohexyl acetate 30.62
    tetrabutyl urea 25.13
    diisobutyl methanol 9.42
    2-phenylethanol 16.07
    styrene 8.18
    dioctyl adipate 25.66
    dimethyl sulfate 26.19
    ethyl butyrate 23.14
    methyl lactate 15.8
    butyl lactate 33.35
    diethyl carbonate 14.03
    propanediol butyl ether 40.23
    triethyl orthoformate 24.74
    p-tert-butyltoluene 7.15
    methyl 4-tert-butylbenzoate 41.99
    morpholine 48.01
    tert-butylamine 13.1
    n-dodecanol 5.77
    dimethoxymethane 29.94
    ethylene carbonate 18.26
    cyrene 52.39
    2-ethoxyethyl acetate 44.42
    2-ethylhexyl acetate 23.86
    1,2,4-trichlorobenzene 20.16
    4-methylpyridine 24.51
    dibutyl ether 19.2
    2,6-dimethyl-4-heptanol 9.42
    DEF 41.92
    dimethyl isosorbide 93.43
    tetrachloroethylene 35.54
    eugenol 37.83
    triacetin 45.49
    span 80 39.68
    1,4-butanediol 7.78
    1,1-dichloroethane 20.34
    2-methyl-1-pentanol 22.49
    methyl formate 9.35
    2-methyl-1-butanol 16.13
    n-decane 1.48
    butyronitrile 8.94
    3,7-dimethyl-1-octanol 14.21
    1-chlorooctane 8.0
    1-chlorotetradecane 2.68
    n-nonane 1.26
    undecane 0.98
    tert-butylcyclohexane 2.74
    cyclooctane 0.99
    cyclopentanol 20.61
    tetrahydropyran 32.88
    tert-amyl methyl ether 25.11
    2,5,8-trioxanonane 85.32
    1-hexene 6.56
    2-isopropoxyethanol 37.5
    2,2,2-trifluoroethanol 8.38
    methyl butyrate 35.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction