N-Methylisopropylamine

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  • Identifiers

    CAS number
    4747-21-1

    Molecular formula
    C4H11N

    SMILES
    CC(C)NC

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Cheesy 76.82%
    Fishy 74.42%
    Ripe 55.14%
    Fermented 29.37%
    Pungent 24.55%
    Meaty 23.84%
    Sweaty 23.24%
    Oily 22.6%
    Musty 21.18%
    Sulfurous 20.6%

     

    Flavor
    Fishy 47.32%
    Ammoniacal 34.16%
    Ammonia 25.46%
    Meaty 25.21%
    Glue 22.3%
    Bloody 22.26%
    Sulfurous 22.11%
    Onion 21.69%
    Yeasty 21.19%
    Skunky 20.18%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    8.7 (weak base)

    Molecular weight
    73.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    51°C

    Flash point

    • -22.3 ˚C est.

  • Synonyms

    • N-Isopropylmethylamine
    • 4747-21-1
    • N-Methylisopropylamine
    • Methylisopropylamine
    • Isopropylmethylamine
    • 2-Methylaminopropane
    • N-Isopropyl-N-methylamine
    • Ethylamine, N,1-dimethyl-
    • N-methyl-2-propanamine
    • N-methyl-N-isopropylamine
    • methyl(1-methylethyl)amine
    • N,1-Dimethylethylamine
    • J3OL90426G
    • NSC 1065
    • NSC-1065
    • EINECS 225-266-7
    • 2-(METHYLAMINO)PROPANE
    • ISOPROPYLAMINE, N-METHYL-
    • DTXSID80871098
    • N-Methyl-N-(1-methylethyl)amine
    • EC 225-266-7
    • N-methyl-N-[1-methylethyl]amine
    • RefChem:830731
    • DTXCID70818770
    • Ethylamine, N,1-dimethyl-(8CI)
    • 225-266-7
    • N-methylpropan-2-amine
    • 2-Propanamine, N-methyl-
    • Methyl(Propan-2-Yl)Amine
    • MFCD00042859
    • isopropyl-methyl-amine
    • N-methylisopropyylamine
    • UNII-J3OL90426G
    • isopropylmethyamine
    • i-propylmethyl amine
    • isopropyl-methylamine
    • methyl isopropylamine
    • methyl-isopropylamine
    • methylisopropyl amine
    • isopropyl(methyl)amine
    • N-isopropyl-methylamine
    • N-methyl-isopropylamine
    • N-methylisopropyl amine
    • isopropyl(methyl)-amine
    • Ethylamine,1-dimethyl-
    • N-isopropyl-methyl-amine
    • N-methyl-iso-propylamine
    • N-isopropyl N-methylamine
    • SCHEMBL37550
    • SCHEMBL49734
    • N-Isopropyl-N-methylamine #
    • N-Isopropylmethylamine, 98%
    • SCHEMBL214411
    • SCHEMBL359952
    • SCHEMBL1004463
    • SCHEMBL4648196
    • SCHEMBL6264375
    • SCHEMBL8900657
    • SCHEMBL28853742
    • NSC1065
    • STR05622
    • AKOS000120389
    • BP-13331
    • DB-000334
    • M2429
    • NS00008239
    • EN300-20275
    • N-Isopropylmethylamine, purum, >=98.0% (GC)
    • 747I211
    • F094496
    • InChI=1/C4H11N/c1-4(2)5-3/h4-5H,1-3H
    • Q27281162
    • 4747-21-1

  • Applications

    N-Methylisopropylamine is a secondary amine primarily employed as an intermediate in the synthesis of pharmaceutical and agrochemical compounds, providing a building block for various drug and pest-control agents. It is also used as a reagent for preparing specialty chemicals and can act as a reaction partner or solvent in chemical manufacturing processes. In the plastics and coatings sector, the amine may serve as a functional component to improve adhesion and as a curing or modifying agent in epoxy and other polymer systems. More broadly it is handled as a reactive building block in additional specialty syntheses, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 414.12
    methanol 525.94
    isopropanol 280.6
    water 18.07
    ethyl acetate 176.72
    n-propanol 361.99
    acetone 184.25
    n-butanol 340.14
    acetonitrile 178.77
    DMF 240.83
    toluene 62.04
    isobutanol 205.57
    1,4-dioxane 239.6
    methyl acetate 184.51
    THF 429.29
    2-butanone 196.26
    n-pentanol 183.54
    sec-butanol 273.23
    n-hexane 57.79
    ethylene glycol 162.63
    NMP 319.53
    cyclohexane 80.55
    DMSO 196.76
    n-butyl acetate 185.49
    n-octanol 114.91
    chloroform 614.27
    n-propyl acetate 82.3
    acetic acid 427.15
    dichloromethane 345.16
    cyclohexanone 235.16
    propylene glycol 240.67
    isopropyl acetate 83.65
    DMAc 247.51
    2-ethoxyethanol 191.28
    isopentanol 169.62
    n-heptane 91.37
    ethyl formate 145.99
    1,2-dichloroethane 163.57
    n-hexanol 320.22
    2-methoxyethanol 380.62
    isobutyl acetate 50.0
    tetrachloromethane 203.02
    n-pentyl acetate 97.7
    transcutol 368.98
    n-heptanol 141.88
    ethylbenzene 26.13
    MIBK 56.43
    2-propoxyethanol 347.76
    tert-butanol 232.28
    MTBE 140.19
    2-butoxyethanol 190.88
    propionic acid 341.6
    o-xylene 46.08
    formic acid 206.58
    diethyl ether 185.63
    m-xylene 37.02
    p-xylene 36.92
    chlorobenzene 105.36
    dimethyl carbonate 41.05
    n-octane 24.54
    formamide 165.18
    cyclopentanone 304.14
    2-pentanone 133.19
    anisole 57.26
    cyclopentyl methyl ether 173.05
    gamma-butyrolactone 316.09
    1-methoxy-2-propanol 263.65
    pyridine 218.34
    3-pentanone 123.32
    furfural 266.74
    n-dodecane 15.41
    diethylene glycol 234.65
    diisopropyl ether 38.71
    tert-amyl alcohol 227.26
    acetylacetone 98.27
    n-hexadecane 15.84
    acetophenone 57.12
    methyl propionate 142.53
    isopentyl acetate 119.43
    trichloroethylene 302.14
    n-nonanol 100.08
    cyclohexanol 220.87
    benzyl alcohol 85.71
    2-ethylhexanol 177.54
    isooctanol 85.62
    dipropyl ether 165.67
    1,2-dichlorobenzene 85.59
    ethyl lactate 66.95
    propylene carbonate 162.29
    n-methylformamide 208.68
    2-pentanol 175.99
    n-pentane 73.99
    1-propoxy-2-propanol 299.14
    1-methoxy-2-propyl acetate 121.11
    2-(2-methoxypropoxy) propanol 109.19
    mesitylene 20.56
    ε-caprolactone 210.92
    p-cymene 43.98
    epichlorohydrin 223.67
    1,1,1-trichloroethane 214.2
    2-aminoethanol 288.28
    morpholine-4-carbaldehyde 236.26
    sulfolane 292.55
    2,2,4-trimethylpentane 28.79
    2-methyltetrahydrofuran 313.51
    n-hexyl acetate 119.41
    isooctane 12.17
    2-(2-butoxyethoxy)ethanol 165.57
    sec-butyl acetate 52.03
    tert-butyl acetate 69.14
    decalin 20.08
    glycerin 254.29
    diglyme 224.41
    acrylic acid 297.58
    isopropyl myristate 44.26
    n-butyric acid 381.89
    acetyl acetate 101.95
    di(2-ethylhexyl) phthalate 49.3
    ethyl propionate 76.33
    nitromethane 293.68
    1,2-diethoxyethane 136.91
    benzonitrile 100.24
    trioctyl phosphate 41.62
    1-bromopropane 164.56
    gamma-valerolactone 285.4
    n-decanol 72.59
    triethyl phosphate 49.95
    4-methyl-2-pentanol 68.68
    propionitrile 200.89
    vinylene carbonate 133.07
    1,1,2-trichlorotrifluoroethane 316.66
    DMS 58.29
    cumene 22.86
    2-octanol 80.67
    2-hexanone 89.56
    octyl acetate 67.98
    limonene 83.09
    1,2-dimethoxyethane 174.28
    ethyl orthosilicate 54.29
    tributyl phosphate 48.79
    diacetone alcohol 115.7
    N,N-dimethylaniline 43.37
    acrylonitrile 201.91
    aniline 156.22
    1,3-propanediol 292.82
    bromobenzene 83.98
    dibromomethane 274.24
    1,1,2,2-tetrachloroethane 292.02
    2-methyl-cyclohexyl acetate 80.17
    tetrabutyl urea 61.56
    diisobutyl methanol 67.14
    2-phenylethanol 114.67
    styrene 38.07
    dioctyl adipate 57.77
    dimethyl sulfate 61.38
    ethyl butyrate 116.28
    methyl lactate 109.64
    butyl lactate 99.52
    diethyl carbonate 66.9
    propanediol butyl ether 146.74
    triethyl orthoformate 91.81
    p-tert-butyltoluene 43.51
    methyl 4-tert-butylbenzoate 73.12
    morpholine 328.33
    tert-butylamine 168.15
    n-dodecanol 55.49
    dimethoxymethane 111.95
    ethylene carbonate 118.83
    cyrene 89.05
    2-ethoxyethyl acetate 103.46
    2-ethylhexyl acetate 106.63
    1,2,4-trichlorobenzene 105.03
    4-methylpyridine 167.04
    dibutyl ether 103.3
    2,6-dimethyl-4-heptanol 67.14
    DEF 168.71
    dimethyl isosorbide 127.3
    tetrachloroethylene 264.02
    eugenol 80.45
    triacetin 88.06
    span 80 145.95
    1,4-butanediol 116.86
    1,1-dichloroethane 224.82
    2-methyl-1-pentanol 116.72
    methyl formate 126.16
    2-methyl-1-butanol 198.97
    n-decane 26.77
    butyronitrile 197.81
    3,7-dimethyl-1-octanol 94.38
    1-chlorooctane 62.69
    1-chlorotetradecane 25.18
    n-nonane 28.04
    undecane 19.38
    tert-butylcyclohexane 20.71
    cyclooctane 24.62
    cyclopentanol 297.97
    tetrahydropyran 290.74
    tert-amyl methyl ether 124.88
    2,5,8-trioxanonane 146.86
    1-hexene 108.42
    2-isopropoxyethanol 124.93
    2,2,2-trifluoroethanol 164.24
    methyl butyrate 96.9

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction