N-lactoyl ethanolamine phosphate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    782498-03-7

    Molecular formula
    C5H12NO6P

    SMILES
    CC(C(=O)NCCOP(=O)(O)O)O

  • Odor profile

    Fragrance
    Odorless 69.64%
    Savory 30.97%
    Sweet 27.64%
    Meaty 20.52%
    Milky 19.81%
    Cooling 18.18%
    Alcoholic 17.71%
    Buttery 16.73%
    Cooked 16.53%
    Clean 15.41%

     

    Flavor
    Odorless 75.78%
    Very mild 33.59%
    Mild 31.95%
    Bland 28.64%
    Sour 27.03%
    Sweet-like 24.69%
    Yeast 23.81%
    Faint 21.63%
    Acidic 21.13%
    Caramellic 20.21%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.5

    pKa est.
    9.03 (weak base)

    Molecular weight
    213.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    537°C

    Flash point

    • 247.99 ˚C est.

    Solubility expt.

    • Very soluble in water; insoluble in pentane
    • Slightly soluble (in ethanol)

  • Synonyms

    • N-lactoyl ethanolamine phosphate
    • FEMA no. 4257
    • 1NR0E369CN
    • UNII-1NR0E369CN
    • (+/-)-N-lactoyl ethanolamine phosphate
    • N-Lactoyl ethanolamine phosphate [FHFI]
    • 782498-03-7
    • N-Lactoyl ethanolamine phosphate, (+/-)-
    • 2-Hydroxy-N-(2-(phosphonooxy)ethyl)propanamide
    • Propanamide, 2-hydroxy-N-(2-(phosphonooxy)ethyl)-
    • LACTOYL MONOETHANOLAMIDE PHOSPHATE
    • [2-(2-hydroxypropanamido)ethoxy]phosphonic acid
    • (2-(2-hydroxypropanamido)ethoxy)phosphonic acid
    • 2-Hydroxy-N-[2-(phosphonooxy)ethyl]propanamide
    • SCHEMBL1399083
    • CHEBI:178342
    • NS00120721
    • 2-Hydroxy-N-[2-(phosphonooxy)ethyl]-Propanamide
    • 2-(2-hydroxypropanoylamino)ethyl dihydrogen phosphate
    • Q27252659

  • Applications

    N-lactoyl ethanolamine phosphate (CAS 782498-03-7) is used as an intermediate and building block for phosphate-containing compounds, including phosphate esters and phospholipid-like molecules in chemical synthesis. In formulations, it can function as a surfactant or emulsifier and as a wetting agent in cosmetics and cleaning products; as a stabilizer and functional additive in polymer, coating, and ink systems; and as a chelating/complexing agent for metal ions in industrial processing and water treatment. It may also be evaluated as a reactive building block for phospholipid mimetics and related bioactive derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.37
    methanol 4.55
    isopropanol 1.01
    water 112.62
    ethyl acetate 0.52
    n-propanol 0.84
    acetone 1.78
    n-butanol 0.75
    acetonitrile 0.32
    DMF 30.58
    toluene 0.41
    isobutanol 0.56
    1,4-dioxane 1.22
    methyl acetate 0.49
    THF 2.83
    2-butanone 0.73
    n-pentanol 0.49
    sec-butanol 0.89
    n-hexane 0.15
    ethylene glycol 11.11
    NMP 33.48
    cyclohexane 0.28
    DMSO 54.4
    n-butyl acetate 0.54
    n-octanol 0.7
    chloroform 0.19
    n-propyl acetate 0.31
    acetic acid 4.36
    dichloromethane 0.29
    cyclohexanone 1.7
    propylene glycol 6.34
    isopropyl acetate 0.53
    DMAc 21.9
    2-ethoxyethanol 6.32
    isopentanol 0.8
    n-heptane 0.32
    ethyl formate 1.23
    1,2-dichloroethane 0.37
    n-hexanol 0.85
    2-methoxyethanol 16.01
    isobutyl acetate 0.13
    tetrachloromethane 0.2
    n-pentyl acetate 0.58
    transcutol 6.55
    n-heptanol 0.97
    ethylbenzene 0.26
    MIBK 0.95
    2-propoxyethanol 5.03
    tert-butanol 3.09
    MTBE 0.73
    2-butoxyethanol 3.3
    propionic acid 1.34
    o-xylene 0.87
    formic acid 36.7
    diethyl ether 0.56
    m-xylene 0.53
    p-xylene 0.3
    chlorobenzene 0.14
    dimethyl carbonate 1.53
    n-octane 0.16
    formamide 30.85
    cyclopentanone 2.84
    2-pentanone 1.04
    anisole 0.54
    cyclopentyl methyl ether 1.72
    gamma-butyrolactone 3.63
    1-methoxy-2-propanol 9.46
    pyridine 0.81
    3-pentanone 0.77
    furfural 7.59
    n-dodecane 0.08
    diethylene glycol 14.1
    diisopropyl ether 0.38
    tert-amyl alcohol 2.58
    acetylacetone 2.65
    n-hexadecane 0.08
    acetophenone 1.04
    methyl propionate 0.95
    isopentyl acetate 0.51
    trichloroethylene 0.41
    n-nonanol 0.7
    cyclohexanol 1.21
    benzyl alcohol 0.97
    2-ethylhexanol 0.61
    isooctanol 0.72
    dipropyl ether 0.66
    1,2-dichlorobenzene 0.24
    ethyl lactate 1.6
    propylene carbonate 1.74
    n-methylformamide 9.02
    2-pentanol 0.73
    n-pentane 0.17
    1-propoxy-2-propanol 3.25
    1-methoxy-2-propyl acetate 1.47
    2-(2-methoxypropoxy) propanol 4.8
    mesitylene 0.55
    ε-caprolactone 1.63
    p-cymene 0.47
    epichlorohydrin 1.53
    1,1,1-trichloroethane 0.19
    2-aminoethanol 8.19
    morpholine-4-carbaldehyde 15.81
    sulfolane 20.65
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 1.19
    n-hexyl acetate 0.67
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 5.03
    sec-butyl acetate 0.25
    tert-butyl acetate 1.1
    decalin 0.12
    glycerin 32.73
    diglyme 7.58
    acrylic acid 2.52
    isopropyl myristate 0.36
    n-butyric acid 1.42
    acetyl acetate 0.51
    di(2-ethylhexyl) phthalate 0.81
    ethyl propionate 0.44
    nitromethane 5.44
    1,2-diethoxyethane 0.79
    benzonitrile 0.41
    trioctyl phosphate 0.69
    1-bromopropane 0.16
    gamma-valerolactone 6.44
    n-decanol 0.56
    triethyl phosphate 0.79
    4-methyl-2-pentanol 0.61
    propionitrile 0.25
    vinylene carbonate 1.4
    1,1,2-trichlorotrifluoroethane 7.06
    DMS 0.64
    cumene 0.27
    2-octanol 0.65
    2-hexanone 0.42
    octyl acetate 0.5
    limonene 0.62
    1,2-dimethoxyethane 5.67
    ethyl orthosilicate 0.75
    tributyl phosphate 0.63
    diacetone alcohol 4.86
    N,N-dimethylaniline 1.18
    acrylonitrile 0.52
    aniline 0.84
    1,3-propanediol 6.58
    bromobenzene 0.12
    dibromomethane 0.21
    1,1,2,2-tetrachloroethane 0.61
    2-methyl-cyclohexyl acetate 0.67
    tetrabutyl urea 1.51
    diisobutyl methanol 0.67
    2-phenylethanol 0.98
    styrene 0.2
    dioctyl adipate 0.56
    dimethyl sulfate 6.57
    ethyl butyrate 0.57
    methyl lactate 4.63
    butyl lactate 1.53
    diethyl carbonate 0.39
    propanediol butyl ether 4.17
    triethyl orthoformate 0.74
    p-tert-butyltoluene 0.51
    methyl 4-tert-butylbenzoate 2.81
    morpholine 1.93
    tert-butylamine 1.17
    n-dodecanol 0.44
    dimethoxymethane 7.17
    ethylene carbonate 0.88
    cyrene 7.73
    2-ethoxyethyl acetate 0.87
    2-ethylhexyl acetate 0.4
    1,2,4-trichlorobenzene 0.31
    4-methylpyridine 0.92
    dibutyl ether 0.35
    2,6-dimethyl-4-heptanol 0.67
    DEF 3.26
    dimethyl isosorbide 7.41
    tetrachloroethylene 0.65
    eugenol 3.73
    triacetin 1.19
    span 80 3.13
    1,4-butanediol 2.92
    1,1-dichloroethane 0.16
    2-methyl-1-pentanol 0.52
    methyl formate 6.13
    2-methyl-1-butanol 0.73
    n-decane 0.13
    butyronitrile 0.3
    3,7-dimethyl-1-octanol 0.53
    1-chlorooctane 0.23
    1-chlorotetradecane 0.12
    n-nonane 0.14
    undecane 0.1
    tert-butylcyclohexane 0.09
    cyclooctane 0.22
    cyclopentanol 1.64
    tetrahydropyran 0.58
    tert-amyl methyl ether 1.1
    2,5,8-trioxanonane 8.26
    1-hexene 0.18
    2-isopropoxyethanol 2.49
    2,2,2-trifluoroethanol 5.0
    methyl butyrate 0.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction