N-Ethyl-p-toluidine

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  • Identifiers

    CAS number
    622-57-1

    Molecular formula
    C9H13N

    SMILES
    CCNC1=CC=C(C=C1)C

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fishy 46.75%
    Cheesy 43.5%
    Animal 39.59%
    Meaty 37.86%
    Ripe 33.13%
    Roasted 32.53%
    Burnt 30.58%
    Sulfurous 29.0%
    Smoky 26.53%
    Floral 24.78%

     

    Flavor
    Meaty 38.02%
    Phenolic 37.09%
    Sweet 31.47%
    Medicinal 30.29%
    Floral 30.23%
    Spicy 29.32%
    Sulfurous 29.08%
    Mild 28.42%
    Fishy 28.34%
    Roasted 24.01%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    5.73 (weak acid)

    Molecular weight
    135.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    220°C

    Flash point

    • 86.52 ˚C est.

  • Synonyms

    • N-Ethyl-p-toluidine
    • N-Ethyl-4-methylaniline
    • 622-57-1
    • N-Ethyl-4-toluidine
    • BENZENAMINE, N-ETHYL-4-METHYL-
    • N-Ethyl-p-methylaniline
    • p-Methyl-N-ethylaniline
    • p-Toluidine, N-ethyl-
    • N-ethyl-4-methyl-aniline
    • NSC 8889
    • W991US1LF2
    • NSC-8889
    • EINECS 210-742-9
    • DTXSID7060754
    • N-ETHYL-4-METHYLBENZENAMINE
    • aniline, N-ethyl-4-methyl-
    • ethyl toluidine
    • NSC8889
    • N-Athyl-p-toluidin
    • MFCD00035793
    • 4-(Ethylamino)toluene
    • UNII-W991US1LF2
    • N-Ethyl-4-methyl-benzenamine
    • N-ETHYL-PARA-TOLUIDINE
    • SCHEMBL247849
    • p-Toluidine, N-ethyl-(8CI)
    • DTXCID5043269
    • N-Ethyl-N-(4-methylphenyl)amine
    • ALBB-020221
    • N-Ethyl-N-(4-methylphenyl)amine #
    • AKOS000241591
    • ethyl(4-methylphenyl)amine hydrochloride
    • BS-42310
    • DB-054109
    • E0179
    • NS00034982
    • EN300-33071
    • D90452
    • Q63391562
    • 210-742-9

  • Applications

    N-Ethyl-p-toluidine is primarily used as an intermediate in the synthesis of dyes and colorants, notably azo dyes and aryl pigments. It is employed in textile dye production and for color applications in coatings, paints, inks, and plastics. In the rubber and elastomer sector, it often serves as a chemical intermediate to furnish colorants and related additives. Additionally, it is commonly evaluated as an intermediate in pharmaceutical and agrochemical synthesis, depending on local regulatory requirements and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 399.65
    methanol 388.17
    isopropanol 231.43
    water 0.49
    ethyl acetate 413.52
    n-propanol 329.47
    acetone 477.51
    n-butanol 363.26
    acetonitrile 255.78
    DMF 507.94
    toluene 238.5
    isobutanol 221.16
    1,4-dioxane 775.53
    methyl acetate 320.44
    THF 861.59
    2-butanone 358.28
    n-pentanol 257.13
    sec-butanol 220.47
    n-hexane 159.99
    ethylene glycol 78.09
    NMP 382.6
    cyclohexane 173.1
    DMSO 545.49
    n-butyl acetate 478.73
    n-octanol 152.64
    chloroform 994.69
    n-propyl acetate 207.39
    acetic acid 254.57
    dichloromethane 766.64
    cyclohexanone 464.01
    propylene glycol 110.3
    isopropyl acetate 210.54
    DMAc 459.47
    2-ethoxyethanol 244.8
    isopentanol 266.67
    n-heptane 128.86
    ethyl formate 213.76
    1,2-dichloroethane 461.58
    n-hexanol 513.93
    2-methoxyethanol 369.53
    isobutyl acetate 150.82
    tetrachloromethane 203.47
    n-pentyl acetate 158.86
    transcutol 692.93
    n-heptanol 148.78
    ethylbenzene 93.85
    MIBK 180.15
    2-propoxyethanol 507.93
    tert-butanol 299.41
    MTBE 389.84
    2-butoxyethanol 193.02
    propionic acid 219.03
    o-xylene 119.42
    formic acid 70.01
    diethyl ether 591.56
    m-xylene 127.46
    p-xylene 113.2
    chlorobenzene 278.43
    dimethyl carbonate 122.8
    n-octane 43.64
    formamide 80.73
    cyclopentanone 508.3
    2-pentanone 334.36
    anisole 179.58
    cyclopentyl methyl ether 403.12
    gamma-butyrolactone 468.34
    1-methoxy-2-propanol 285.6
    pyridine 519.25
    3-pentanone 291.7
    furfural 361.08
    n-dodecane 30.68
    diethylene glycol 265.04
    diisopropyl ether 141.77
    tert-amyl alcohol 245.25
    acetylacetone 275.99
    n-hexadecane 34.02
    acetophenone 144.89
    methyl propionate 276.71
    isopentyl acetate 319.26
    trichloroethylene 715.04
    n-nonanol 133.3
    cyclohexanol 238.68
    benzyl alcohol 139.08
    2-ethylhexanol 277.03
    isooctanol 110.58
    dipropyl ether 440.71
    1,2-dichlorobenzene 213.04
    ethyl lactate 92.31
    propylene carbonate 288.35
    n-methylformamide 175.0
    2-pentanol 214.99
    n-pentane 117.56
    1-propoxy-2-propanol 369.4
    1-methoxy-2-propyl acetate 292.24
    2-(2-methoxypropoxy) propanol 176.57
    mesitylene 83.26
    ε-caprolactone 354.47
    p-cymene 87.41
    epichlorohydrin 472.28
    1,1,1-trichloroethane 453.66
    2-aminoethanol 139.73
    morpholine-4-carbaldehyde 401.06
    sulfolane 481.71
    2,2,4-trimethylpentane 51.27
    2-methyltetrahydrofuran 579.96
    n-hexyl acetate 224.37
    isooctane 37.59
    2-(2-butoxyethoxy)ethanol 243.13
    sec-butyl acetate 137.07
    tert-butyl acetate 210.46
    decalin 64.38
    glycerin 133.24
    diglyme 418.46
    acrylic acid 174.73
    isopropyl myristate 95.91
    n-butyric acid 364.22
    acetyl acetate 230.64
    di(2-ethylhexyl) phthalate 89.94
    ethyl propionate 182.58
    nitromethane 336.93
    1,2-diethoxyethane 409.48
    benzonitrile 186.68
    trioctyl phosphate 72.73
    1-bromopropane 409.5
    gamma-valerolactone 490.0
    n-decanol 105.37
    triethyl phosphate 100.06
    4-methyl-2-pentanol 121.17
    propionitrile 281.36
    vinylene carbonate 243.44
    1,1,2-trichlorotrifluoroethane 346.81
    DMS 153.39
    cumene 70.62
    2-octanol 96.0
    2-hexanone 240.75
    octyl acetate 119.83
    limonene 155.72
    1,2-dimethoxyethane 486.85
    ethyl orthosilicate 111.88
    tributyl phosphate 88.31
    diacetone alcohol 185.23
    N,N-dimethylaniline 126.05
    acrylonitrile 264.29
    aniline 233.23
    1,3-propanediol 186.31
    bromobenzene 315.3
    dibromomethane 601.0
    1,1,2,2-tetrachloroethane 627.51
    2-methyl-cyclohexyl acetate 167.97
    tetrabutyl urea 113.25
    diisobutyl methanol 128.96
    2-phenylethanol 194.45
    styrene 138.54
    dioctyl adipate 113.73
    dimethyl sulfate 167.54
    ethyl butyrate 266.44
    methyl lactate 115.17
    butyl lactate 114.61
    diethyl carbonate 152.19
    propanediol butyl ether 151.57
    triethyl orthoformate 185.09
    p-tert-butyltoluene 94.06
    methyl 4-tert-butylbenzoate 137.48
    morpholine 749.76
    tert-butylamine 227.27
    n-dodecanol 89.41
    dimethoxymethane 376.97
    ethylene carbonate 229.91
    cyrene 147.17
    2-ethoxyethyl acetate 194.91
    2-ethylhexyl acetate 276.5
    1,2,4-trichlorobenzene 231.28
    4-methylpyridine 418.15
    dibutyl ether 240.2
    2,6-dimethyl-4-heptanol 128.96
    DEF 366.54
    dimethyl isosorbide 266.22
    tetrachloroethylene 455.26
    eugenol 138.42
    triacetin 161.13
    span 80 174.51
    1,4-butanediol 85.66
    1,1-dichloroethane 468.86
    2-methyl-1-pentanol 214.6
    methyl formate 145.53
    2-methyl-1-butanol 259.07
    n-decane 50.66
    butyronitrile 326.3
    3,7-dimethyl-1-octanol 146.93
    1-chlorooctane 140.26
    1-chlorotetradecane 61.36
    n-nonane 54.1
    undecane 37.38
    tert-butylcyclohexane 59.94
    cyclooctane 60.71
    cyclopentanol 223.07
    tetrahydropyran 801.55
    tert-amyl methyl ether 266.55
    2,5,8-trioxanonane 292.32
    1-hexene 347.64
    2-isopropoxyethanol 176.39
    2,2,2-trifluoroethanol 72.17
    methyl butyrate 239.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction