N-Butylacetamide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1119-49-9

    Molecular formula
    C6H13NO

    SMILES
    CCCCNC(=O)C

    Safety labels

  • Odor profile

    Fragrance
    Cheesy 57.97%
    Fishy 48.22%
    Meaty 35.76%
    Savory 28.92%
    Ripe 28.9%
    Pungent 26.73%
    Roasted 25.89%
    Mint 23.42%
    Herbal 22.99%
    Cooling 21.19%

     

    Flavor
    Cheese 38.9%
    Fruity 32.01%
    Sulfury 28.3%
    Sweat 27.71%
    Sweaty 27.08%
    Fishy 26.95%
    Fatty 26.36%
    Cheesy 25.81%
    Sour 25.37%
    Oily 25.3%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    8.32 (weak base)

    Molecular weight
    115.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    236°C

    Flash point

    • 84.91 ˚C est.

  • Synonyms

    • N-Butylacetamide
    • 1119-49-9
    • ACETAMIDE, N-BUTYL-
    • EINECS 214-280-9
    • 45F5O38HJS
    • NSC 27204
    • NSC-27204
    • AI3-02183
    • DTXSID2061511
    • RefChem:829424
    • DTXCID1033248
    • 214-280-9
    • InChI=1/C6H13NO/c1-3-4-5-7-6(2)8/h3-5H2,1-2H3,(H,7,8
    • N-butyl-acetamide
    • n-butylacetamid
    • N-butylethanamide
    • n-n-butylacetamide
    • NSC27204
    • butane, 1-acetamido-
    • UNII-45F5O38HJS
    • SCHEMBL48873
    • N-butylacetamide, AldrichCPR
    • N-(3-Methylbutyl)-Acetamide
    • SCHEMBL211011
    • SCHEMBL497606
    • SCHEMBL827114
    • SCHEMBL998029
    • SCHEMBL6992506
    • SCHEMBL8191940
    • MFCD00041932
    • AKOS003856742
    • AS-85231
    • DB-321027
    • NS00023592
    • H55433
    • 10.14272/GYLDXXLJMRTVSS-UHFFFAOYSA-N.1
    • doi:10.14272/GYLDXXLJMRTVSS-UHFFFAOYSA-N.1
    • Q63408595
    • 1119-49-9

  • Applications

    N-Butylacetamide (CAS 1119-49-9) is primarily used as a polar aprotic solvent and reaction medium in organic synthesis, enabling solubility of diverse substrates and supporting transformations such as acylation; it also serves as an intermediate in the manufacture of pharmaceutical and agrochemical compounds. In industrial contexts it can function as a solvent or processing aid in coatings, inks, and adhesives, and as a solvent or swelling agent in polymer formulations to aid processing and formulation stability. It may be present in cleaning formulations for industrial use due to its solvency properties. All uses are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 928.82
    methanol 1566.79
    isopropanol 562.49
    water 25.06
    ethyl acetate 97.22
    n-propanol 553.87
    acetone 252.69
    n-butanol 445.78
    acetonitrile 189.68
    DMF 514.42
    toluene 36.0
    isobutanol 322.55
    1,4-dioxane 314.35
    methyl acetate 104.28
    THF 484.33
    2-butanone 129.67
    n-pentanol 233.59
    sec-butanol 347.95
    n-hexane 26.93
    ethylene glycol 334.58
    NMP 446.37
    cyclohexane 39.08
    DMSO 481.25
    n-butyl acetate 107.76
    n-octanol 114.01
    chloroform 437.07
    n-propyl acetate 59.61
    acetic acid 764.57
    dichloromethane 305.16
    cyclohexanone 279.42
    propylene glycol 445.77
    isopropyl acetate 64.03
    DMAc 306.46
    2-ethoxyethanol 233.22
    isopentanol 247.32
    n-heptane 21.46
    ethyl formate 135.78
    1,2-dichloroethane 119.56
    n-hexanol 269.99
    2-methoxyethanol 568.65
    isobutyl acetate 47.43
    tetrachloromethane 64.49
    n-pentyl acetate 78.38
    transcutol 481.78
    n-heptanol 102.76
    ethylbenzene 24.03
    MIBK 60.57
    2-propoxyethanol 312.17
    tert-butanol 394.15
    MTBE 112.14
    2-butoxyethanol 162.87
    propionic acid 413.26
    o-xylene 34.32
    formic acid 373.39
    diethyl ether 106.97
    m-xylene 29.94
    p-xylene 38.12
    chlorobenzene 80.67
    dimethyl carbonate 30.97
    n-octane 8.24
    formamide 244.05
    cyclopentanone 328.2
    2-pentanone 109.31
    anisole 63.09
    cyclopentyl methyl ether 144.89
    gamma-butyrolactone 349.98
    1-methoxy-2-propanol 355.0
    pyridine 215.31
    3-pentanone 66.43
    furfural 327.24
    n-dodecane 7.77
    diethylene glycol 286.2
    diisopropyl ether 26.76
    tert-amyl alcohol 270.46
    acetylacetone 99.56
    n-hexadecane 8.32
    acetophenone 67.45
    methyl propionate 83.13
    isopentyl acetate 89.55
    trichloroethylene 246.81
    n-nonanol 93.86
    cyclohexanol 281.47
    benzyl alcohol 101.62
    2-ethylhexanol 109.44
    isooctanol 71.94
    dipropyl ether 74.22
    1,2-dichlorobenzene 72.89
    ethyl lactate 64.3
    propylene carbonate 177.33
    n-methylformamide 298.02
    2-pentanol 199.47
    n-pentane 29.16
    1-propoxy-2-propanol 210.28
    1-methoxy-2-propyl acetate 91.84
    2-(2-methoxypropoxy) propanol 144.67
    mesitylene 21.14
    ε-caprolactone 232.77
    p-cymene 27.59
    epichlorohydrin 232.54
    1,1,1-trichloroethane 117.51
    2-aminoethanol 557.0
    morpholine-4-carbaldehyde 353.68
    sulfolane 398.42
    2,2,4-trimethylpentane 12.93
    2-methyltetrahydrofuran 281.91
    n-hexyl acetate 121.39
    isooctane 8.28
    2-(2-butoxyethoxy)ethanol 194.09
    sec-butyl acetate 40.49
    tert-butyl acetate 63.43
    decalin 14.16
    glycerin 458.82
    diglyme 262.52
    acrylic acid 355.41
    isopropyl myristate 46.39
    n-butyric acid 438.22
    acetyl acetate 70.33
    di(2-ethylhexyl) phthalate 67.89
    ethyl propionate 49.71
    nitromethane 390.01
    1,2-diethoxyethane 99.7
    benzonitrile 132.64
    trioctyl phosphate 51.37
    1-bromopropane 94.99
    gamma-valerolactone 398.49
    n-decanol 66.45
    triethyl phosphate 42.42
    4-methyl-2-pentanol 89.05
    propionitrile 176.11
    vinylene carbonate 168.34
    1,1,2-trichlorotrifluoroethane 291.39
    DMS 66.61
    cumene 23.6
    2-octanol 68.15
    2-hexanone 78.9
    octyl acetate 65.63
    limonene 48.5
    1,2-dimethoxyethane 255.61
    ethyl orthosilicate 40.38
    tributyl phosphate 58.23
    diacetone alcohol 124.04
    N,N-dimethylaniline 55.97
    acrylonitrile 198.78
    aniline 114.37
    1,3-propanediol 520.77
    bromobenzene 62.59
    dibromomethane 198.85
    1,1,2,2-tetrachloroethane 230.87
    2-methyl-cyclohexyl acetate 69.15
    tetrabutyl urea 78.29
    diisobutyl methanol 51.67
    2-phenylethanol 109.71
    styrene 32.15
    dioctyl adipate 75.92
    dimethyl sulfate 62.49
    ethyl butyrate 67.07
    methyl lactate 102.77
    butyl lactate 95.66
    diethyl carbonate 48.31
    propanediol butyl ether 216.42
    triethyl orthoformate 57.66
    p-tert-butyltoluene 27.61
    methyl 4-tert-butylbenzoate 91.36
    morpholine 436.33
    tert-butylamine 230.66
    n-dodecanol 49.38
    dimethoxymethane 142.42
    ethylene carbonate 137.32
    cyrene 123.62
    2-ethoxyethyl acetate 85.98
    2-ethylhexyl acetate 68.61
    1,2,4-trichlorobenzene 85.89
    4-methylpyridine 168.52
    dibutyl ether 68.95
    2,6-dimethyl-4-heptanol 51.67
    DEF 155.08
    dimethyl isosorbide 179.54
    tetrachloroethylene 165.58
    eugenol 105.26
    triacetin 109.11
    span 80 181.09
    1,4-butanediol 207.21
    1,1-dichloroethane 150.7
    2-methyl-1-pentanol 159.55
    methyl formate 158.52
    2-methyl-1-butanol 238.55
    n-decane 12.32
    butyronitrile 206.12
    3,7-dimethyl-1-octanol 89.27
    1-chlorooctane 40.06
    1-chlorotetradecane 18.65
    n-nonane 11.93
    undecane 9.37
    tert-butylcyclohexane 14.28
    cyclooctane 9.31
    cyclopentanol 388.61
    tetrahydropyran 296.43
    tert-amyl methyl ether 84.92
    2,5,8-trioxanonane 212.8
    1-hexene 76.19
    2-isopropoxyethanol 134.97
    2,2,2-trifluoroethanol 156.95
    methyl butyrate 83.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction