N-[2-(1H-Indol-1-yl)ethyl]heptadecanamide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    232257-97-5

    Molecular formula
    C27H44N2O

    SMILES
    CCCCCCCCCCCCCCCCC(=O)NCCN1C=CC2=CC=CC=C21

  • Odor profile

    Fragrance
    Waxy 40.34%
    Meaty 34.72%
    Savory 33.06%
    Animal 32.51%
    Fatty 32.17%
    Fishy 30.49%
    Odorless 30.49%
    Oily 24.36%
    Burnt 22.67%
    Cooling 21.48%

     

    Flavor
    Bland 33.01%
    Odorless 29.87%
    Mild 29.71%
    Herbal 22.62%
    Faint 22.14%
    Slightly waxy 20.93%
    Delicate 20.2%
    Bay oil 19.65%
    Waxy 19.55%
    Cedarleaf 19.28%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.1

    pKa est.
    3.86 (weak acid)

    Molecular weight
    412.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    687°C

    Flash point

    • 225.85 ˚C est.

  • Synonyms

    • 232257-97-5
    • N-[2-(1H-Indol-1-yl)ethyl]heptadecanamide
    • N-(2-indol-1-ylethyl)heptadecanamide
    • N-(2-(1H-Indol-1-yl)ethyl)heptadecanamide
    • Margarinsauretryptamid
    • DTXSID10583677
    • Heptadecanoic acid tryptamide, analytical standard

  • Applications

    N-[2-(1H-Indol-1-yl)ethyl]heptadecanamide (CAS 232257-97-5) is a long-chain fatty amide bearing an indole-containing N-substituent; in real-world practice, this structure may be used as a fragrance component or fixative in perfumery and cosmetics, as an odorant in household cleaning products, or as an intermediate in the synthesis of other indole-containing compounds in industrial manufacturing; its hydrophobic C17 tail also makes it a candidate for development as a processing aid or surface-modifying additive in polymers and coatings, including potential incorporation into coatings or inks to influence fragrance release and film formation, all subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 64.55
    methanol 112.77
    isopropanol 39.73
    water 2.4
    ethyl acetate 154.39
    n-propanol 71.31
    acetone 186.61
    n-butanol 69.69
    acetonitrile 55.75
    DMF 203.27
    toluene 61.69
    isobutanol 58.62
    1,4-dioxane 183.86
    methyl acetate 149.52
    THF 412.55
    2-butanone 207.89
    n-pentanol 59.39
    sec-butanol 64.68
    n-hexane 11.41
    ethylene glycol 8.04
    NMP 414.86
    cyclohexane 33.62
    DMSO 215.87
    n-butyl acetate 130.28
    n-octanol 37.59
    chloroform 568.87
    n-propyl acetate 167.6
    acetic acid 132.54
    dichloromethane 682.2
    cyclohexanone 461.17
    propylene glycol 13.77
    isopropyl acetate 116.49
    DMAc 454.49
    2-ethoxyethanol 124.31
    isopentanol 67.81
    n-heptane 9.21
    ethyl formate 107.17
    1,2-dichloroethane 362.29
    n-hexanol 40.23
    2-methoxyethanol 121.53
    isobutyl acetate 109.91
    tetrachloromethane 124.19
    n-pentyl acetate 191.47
    transcutol 332.08
    n-heptanol 48.07
    ethylbenzene 38.39
    MIBK 104.56
    2-propoxyethanol 98.1
    tert-butanol 45.1
    MTBE 87.05
    2-butoxyethanol 128.98
    propionic acid 104.65
    o-xylene 44.0
    formic acid 56.28
    diethyl ether 94.03
    m-xylene 35.22
    p-xylene 61.59
    chlorobenzene 121.89
    dimethyl carbonate 69.57
    n-octane 6.24
    formamide 101.84
    cyclopentanone 422.79
    2-pentanone 160.24
    anisole 87.81
    cyclopentyl methyl ether 168.72
    gamma-butyrolactone 459.87
    1-methoxy-2-propanol 87.24
    pyridine 227.13
    3-pentanone 154.62
    furfural 292.98
    n-dodecane 3.54
    diethylene glycol 46.77
    diisopropyl ether 28.02
    tert-amyl alcohol 68.53
    acetylacetone 194.29
    n-hexadecane 4.14
    acetophenone 132.85
    methyl propionate 140.66
    isopentyl acetate 123.12
    trichloroethylene 563.5
    n-nonanol 40.58
    cyclohexanol 105.32
    benzyl alcohol 75.21
    2-ethylhexanol 38.12
    isooctanol 46.11
    dipropyl ether 68.51
    1,2-dichlorobenzene 132.67
    ethyl lactate 68.71
    propylene carbonate 257.39
    n-methylformamide 109.41
    2-pentanol 44.37
    n-pentane 9.39
    1-propoxy-2-propanol 80.55
    1-methoxy-2-propyl acetate 121.8
    2-(2-methoxypropoxy) propanol 92.07
    mesitylene 22.17
    ε-caprolactone 409.15
    p-cymene 25.85
    epichlorohydrin 451.34
    1,1,1-trichloroethane 284.31
    2-aminoethanol 27.4
    morpholine-4-carbaldehyde 264.71
    sulfolane 507.99
    2,2,4-trimethylpentane 8.39
    2-methyltetrahydrofuran 281.45
    n-hexyl acetate 153.93
    isooctane 3.3
    2-(2-butoxyethoxy)ethanol 124.1
    sec-butyl acetate 117.79
    tert-butyl acetate 121.82
    decalin 11.96
    glycerin 25.03
    diglyme 303.2
    acrylic acid 89.12
    isopropyl myristate 47.87
    n-butyric acid 181.6
    acetyl acetate 105.22
    di(2-ethylhexyl) phthalate 55.41
    ethyl propionate 136.42
    nitromethane 229.81
    1,2-diethoxyethane 160.44
    benzonitrile 83.1
    trioctyl phosphate 38.36
    1-bromopropane 170.66
    gamma-valerolactone 543.97
    n-decanol 26.07
    triethyl phosphate 73.98
    4-methyl-2-pentanol 29.32
    propionitrile 65.05
    vinylene carbonate 220.47
    1,1,2-trichlorotrifluoroethane 300.29
    DMS 114.49
    cumene 28.36
    2-octanol 38.73
    2-hexanone 155.08
    octyl acetate 65.4
    limonene 40.79
    1,2-dimethoxyethane 234.2
    ethyl orthosilicate 75.97
    tributyl phosphate 53.11
    diacetone alcohol 109.64
    N,N-dimethylaniline 59.97
    acrylonitrile 71.7
    aniline 77.55
    1,3-propanediol 52.15
    bromobenzene 126.22
    dibromomethane 377.82
    1,1,2,2-tetrachloroethane 510.99
    2-methyl-cyclohexyl acetate 109.43
    tetrabutyl urea 76.03
    diisobutyl methanol 22.26
    2-phenylethanol 55.85
    styrene 47.43
    dioctyl adipate 88.94
    dimethyl sulfate 135.81
    ethyl butyrate 122.4
    methyl lactate 59.12
    butyl lactate 122.55
    diethyl carbonate 82.83
    propanediol butyl ether 77.62
    triethyl orthoformate 105.05
    p-tert-butyltoluene 20.89
    methyl 4-tert-butylbenzoate 121.53
    morpholine 228.03
    tert-butylamine 29.18
    n-dodecanol 18.27
    dimethoxymethane 144.45
    ethylene carbonate 211.24
    cyrene 118.67
    2-ethoxyethyl acetate 237.47
    2-ethylhexyl acetate 110.67
    1,2,4-trichlorobenzene 164.85
    4-methylpyridine 178.74
    dibutyl ether 76.99
    2,6-dimethyl-4-heptanol 22.26
    DEF 210.44
    dimethyl isosorbide 170.02
    tetrachloroethylene 378.59
    eugenol 113.17
    triacetin 177.43
    span 80 80.86
    1,4-butanediol 29.46
    1,1-dichloroethane 252.12
    2-methyl-1-pentanol 66.81
    methyl formate 86.63
    2-methyl-1-butanol 79.92
    n-decane 7.85
    butyronitrile 76.66
    3,7-dimethyl-1-octanol 34.91
    1-chlorooctane 38.94
    1-chlorotetradecane 11.81
    n-nonane 7.49
    undecane 4.89
    tert-butylcyclohexane 8.2
    cyclooctane 7.85
    cyclopentanol 109.94
    tetrahydropyran 249.01
    tert-amyl methyl ether 84.99
    2,5,8-trioxanonane 157.6
    1-hexene 39.49
    2-isopropoxyethanol 95.95
    2,2,2-trifluoroethanol 92.83
    methyl butyrate 200.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction