Myristyl propionate

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  • Identifiers

    CAS number
    6221-95-0

    Molecular formula
    C17H34O2

    SMILES
    CCCCCCCCCCCCCCOC(=O)CC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 70.29%
    Fatty 69.67%
    Oily 65.78%
    Fruity 53.43%
    Sweet 43.61%
    Creamy 34.26%
    Clean 29.85%
    Floral 29.21%
    Winey 29.17%
    Soapy 28.41%

     

    Flavor
    Waxy 77.62%
    Oily 51.95%
    Soapy 50.55%
    Fatty 47.64%
    Sweet 45.73%
    Fruity 43.14%
    Coconut 40.91%
    Mild 40.21%
    Floral 39.7%
    Clean 37.88%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.1

    pKa est.
    7.42 (neutral)

    Molecular weight
    270.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    329°C

    Flash point

    • 141.75 ˚C est.

  • Synonyms

    • Tetradecyl propionate
    • 6221-95-0
    • MYRISTYL PROPIONATE
    • 1-Tetradecanol, propanoate
    • 1-Tetradecanol, 1-propanoate
    • DERMOL MP
    • P59053E7NJ
    • EINECS 228-300-9
    • SCHERCEMOL MP ESTER
    • TETRAECYL PROPIONATE
    • LONZEST 143-S
    • 1-TETRADECYL PROPANOATE
    • DTXSID20863715
    • WE(14:0/3:0)
    • RefChem:819759
    • DTXCID50812296
    • MYRISTYL PROPIONATE [INCI]
    • tetradecyl propanoate
    • Propanoic acid, tetradecyl ester
    • UNII-P59053E7NJ
    • SCHEMBL112452
    • SCHEMBL5236599
    • SCHEMBL5236604
    • CHEBI:179969
    • LMFA07010415
    • DB-257054
    • NS00013880
    • Q27286215
    • 6221-95-0

  • Applications

    Myristyl propionate (CAS 6221-95-0) is a long-chain ester widely used in cosmetics and personal care as an emollient and solvent for active ingredients and fragrance components; it can also function as a plasticizer or processing aid in certain polymers, coatings, and adhesives, and is considered a fragrance ingredient or fixative in perfumery. In household and cleaning formulations, it may serve as a solvent or fragrance carrier, contributing to formulation texture and spreadability, with use governed by formulation requirements and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 565.52
    methanol 458.47
    isopropanol 870.14
    water 0.03
    ethyl acetate 2969.01
    n-propanol 781.52
    acetone 2059.25
    n-butanol 937.72
    acetonitrile 943.55
    DMF 2064.69
    toluene 1002.15
    isobutanol 832.12
    1,4-dioxane 2210.71
    methyl acetate 1635.16
    THF 4001.0
    2-butanone 2451.06
    n-pentanol 679.84
    sec-butanol 1009.85
    n-hexane 534.18
    ethylene glycol 22.09
    NMP 2755.38
    cyclohexane 1575.59
    DMSO 1936.64
    n-butyl acetate 2916.3
    n-octanol 575.45
    chloroform 4777.02
    n-propyl acetate 3196.11
    acetic acid 588.41
    dichloromethane 5102.16
    cyclohexanone 5476.07
    propylene glycol 82.75
    isopropyl acetate 2528.26
    DMAc 2464.01
    2-ethoxyethanol 989.63
    isopentanol 1153.27
    n-heptane 400.23
    ethyl formate 1116.28
    1,2-dichloroethane 3767.09
    n-hexanol 658.05
    2-methoxyethanol 1076.12
    isobutyl acetate 1830.43
    tetrachloromethane 1190.47
    n-pentyl acetate 2754.48
    transcutol 3981.33
    n-heptanol 517.4
    ethylbenzene 728.42
    MIBK 2058.47
    2-propoxyethanol 1069.65
    tert-butanol 1408.4
    MTBE 2618.28
    2-butoxyethanol 1068.25
    propionic acid 744.62
    o-xylene 801.65
    formic acid 69.96
    diethyl ether 2461.05
    m-xylene 735.24
    p-xylene 1099.81
    chlorobenzene 1606.92
    dimethyl carbonate 378.9
    n-octane 157.07
    formamide 178.99
    cyclopentanone 4299.22
    2-pentanone 2763.25
    anisole 1271.38
    cyclopentyl methyl ether 2992.02
    gamma-butyrolactone 3587.04
    1-methoxy-2-propanol 1218.27
    pyridine 2654.13
    3-pentanone 2021.24
    furfural 2265.75
    n-dodecane 73.96
    diethylene glycol 312.67
    diisopropyl ether 1062.1
    tert-amyl alcohol 1411.15
    acetylacetone 2517.58
    n-hexadecane 94.45
    acetophenone 1400.22
    methyl propionate 1666.55
    isopentyl acetate 2597.41
    trichloroethylene 5503.89
    n-nonanol 547.34
    cyclohexanol 1809.64
    benzyl alcohol 684.57
    2-ethylhexanol 810.89
    isooctanol 585.77
    dipropyl ether 2078.83
    1,2-dichlorobenzene 1743.61
    ethyl lactate 630.91
    propylene carbonate 2000.88
    n-methylformamide 740.9
    2-pentanol 943.07
    n-pentane 312.8
    1-propoxy-2-propanol 1324.82
    1-methoxy-2-propyl acetate 1877.63
    2-(2-methoxypropoxy) propanol 802.29
    mesitylene 576.17
    ε-caprolactone 4215.15
    p-cymene 543.8
    epichlorohydrin 3740.93
    1,1,1-trichloroethane 4183.09
    2-aminoethanol 125.87
    morpholine-4-carbaldehyde 2313.34
    sulfolane 4074.4
    2,2,4-trimethylpentane 201.4
    2-methyltetrahydrofuran 4016.64
    n-hexyl acetate 2560.36
    isooctane 139.91
    2-(2-butoxyethoxy)ethanol 1200.72
    sec-butyl acetate 2275.32
    tert-butyl acetate 2774.54
    decalin 450.86
    glycerin 117.21
    diglyme 2830.12
    acrylic acid 399.86
    isopropyl myristate 777.99
    n-butyric acid 2071.56
    acetyl acetate 1472.93
    di(2-ethylhexyl) phthalate 461.13
    ethyl propionate 2535.9
    nitromethane 1579.67
    1,2-diethoxyethane 2618.31
    benzonitrile 1307.29
    trioctyl phosphate 393.36
    1-bromopropane 2800.68
    gamma-valerolactone 4745.57
    n-decanol 334.28
    triethyl phosphate 837.56
    4-methyl-2-pentanol 631.83
    propionitrile 1253.72
    vinylene carbonate 1506.82
    1,1,2-trichlorotrifluoroethane 1939.54
    DMS 1106.35
    cumene 503.78
    2-octanol 552.43
    2-hexanone 2387.71
    octyl acetate 890.05
    limonene 1124.18
    1,2-dimethoxyethane 3128.78
    ethyl orthosilicate 857.06
    tributyl phosphate 583.11
    diacetone alcohol 1718.26
    N,N-dimethylaniline 856.36
    acrylonitrile 1094.85
    aniline 888.38
    1,3-propanediol 341.57
    bromobenzene 2047.29
    dibromomethane 3691.5
    1,1,2,2-tetrachloroethane 5101.37
    2-methyl-cyclohexyl acetate 1513.41
    tetrabutyl urea 811.66
    diisobutyl methanol 601.83
    2-phenylethanol 653.96
    styrene 939.21
    dioctyl adipate 1068.37
    dimethyl sulfate 716.41
    ethyl butyrate 2687.45
    methyl lactate 419.96
    butyl lactate 1231.03
    diethyl carbonate 1221.51
    propanediol butyl ether 712.14
    triethyl orthoformate 1658.7
    p-tert-butyltoluene 483.29
    methyl 4-tert-butylbenzoate 1159.26
    morpholine 3241.15
    tert-butylamine 1044.13
    n-dodecanol 242.33
    dimethoxymethane 1279.81
    ethylene carbonate 1611.98
    cyrene 729.96
    2-ethoxyethyl acetate 2197.11
    2-ethylhexyl acetate 2179.76
    1,2,4-trichlorobenzene 1868.2
    4-methylpyridine 2719.15
    dibutyl ether 2156.43
    2,6-dimethyl-4-heptanol 601.83
    DEF 3175.0
    dimethyl isosorbide 1704.27
    tetrachloroethylene 3382.55
    eugenol 848.02
    triacetin 1697.95
    span 80 878.72
    1,4-butanediol 144.28
    1,1-dichloroethane 3677.18
    2-methyl-1-pentanol 805.91
    methyl formate 449.83
    2-methyl-1-butanol 1012.47
    n-decane 186.85
    butyronitrile 1744.98
    3,7-dimethyl-1-octanol 673.98
    1-chlorooctane 861.28
    1-chlorotetradecane 246.13
    n-nonane 201.58
    undecane 106.62
    tert-butylcyclohexane 341.15
    cyclooctane 360.35
    cyclopentanol 1525.77
    tetrahydropyran 4505.91
    tert-amyl methyl ether 2002.9
    2,5,8-trioxanonane 1441.71
    1-hexene 1243.22
    2-isopropoxyethanol 970.33
    2,2,2-trifluoroethanol 214.42
    methyl butyrate 3646.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction