Myristyl Nicotinate

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  • Identifiers

    CAS number
    273203-62-6

    Molecular formula
    C20H33NO2

    SMILES
    CCCCCCCCCCCCCCOC(=O)C1=CN=CC=C1

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  • Odor profile

    Fragrance
    Fatty 57.42%
    Waxy 55.37%
    Oily 45.36%
    Floral 38.17%
    Sweet 34.68%
    Balsamic 33.11%
    Fresh 29.72%
    Milky 26.16%
    Buttery 24.82%
    Fruity 24.74%

     

    Flavor
    Waxy 47.6%
    Oily 40.66%
    Fatty 35.57%
    Mild 33.41%
    Balsam 28.32%
    Bland 26.38%
    Faint 25.3%
    Creamy 24.91%
    Fruity 24.66%
    Slightly waxy 22.96%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.9

    pKa est.
    6.24 (neutral)

    Molecular weight
    319.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    437°C

    Flash point

    • 191.36 ˚C est.

  • Synonyms

    • Tetradecyl nicotinate
    • Myristyl nicotinate
    • 273203-62-6
    • 3-Pyridinecarboxylic acid, tetradecyl ester
    • 8QWM6I035C
    • PRO-NAD
    • DTXSID30181770
    • RefChem:926322
    • Tetradecyl-3-pyridinecarboxylate
    • DTXCID70104261
    • tetradecyl pyridine-3-carboxylate
    • MFCD16620608
    • C20H33NO2
    • tetradecylnicotinate
    • UNII-8QWM6I035C
    • Nicotinic acid, tetradecyl ester
    • myristyl-nicotinate
    • Tetradecan-1-ol, nicotinate
    • SCHEMBL135491
    • orb1307026
    • CHEMBL4303439
    • TVGLGJWCZSCAEM-UHFFFAOYSA-N
    • AKOS024258483
    • DS-9346
    • FM44974
    • s10627
    • DA-42952
    • SY025969
    • HY-133027
    • CS-0109493
    • BRD-K88153212-001-01-9
    • Q27270911
    • 273203-62-6

  • Applications

    Myristyl Nicotinate (CAS 273203-62-6) is commonly used in cosmetics and personal care as an emollient and skin-conditioning agent, providing slip and a light occlusive feel in creams, lotions, and makeup formulations; it may serve as a solvent or carrier for active ingredients and fragrance components; it can function as a fragrance solvent or texture enhancer in perfumery; it may act as a plasticizer or lubricating additive in coatings, inks, and polymer formulations; and it is sometimes evaluated as an intermediate in the synthesis of other nicotinate derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 674.38
    methanol 741.84
    isopropanol 653.63
    water 0.68
    ethyl acetate 1779.78
    n-propanol 777.38
    acetone 1991.92
    n-butanol 751.95
    acetonitrile 1034.56
    DMF 2130.98
    toluene 866.74
    isobutanol 659.5
    1,4-dioxane 1346.17
    methyl acetate 1319.55
    THF 2539.6
    2-butanone 1782.44
    n-pentanol 423.44
    sec-butanol 669.5
    n-hexane 86.88
    ethylene glycol 48.27
    NMP 2807.54
    cyclohexane 493.32
    DMSO 2008.17
    n-butyl acetate 1072.29
    n-octanol 194.95
    chloroform 4190.84
    n-propyl acetate 1382.26
    acetic acid 811.17
    dichloromethane 5295.31
    cyclohexanone 4037.25
    propylene glycol 119.38
    isopropyl acetate 1184.45
    DMAc 2491.52
    2-ethoxyethanol 667.98
    isopentanol 739.73
    n-heptane 58.84
    ethyl formate 942.12
    1,2-dichloroethane 4001.8
    n-hexanol 290.37
    2-methoxyethanol 971.95
    isobutyl acetate 809.02
    tetrachloromethane 874.95
    n-pentyl acetate 1098.04
    transcutol 1893.41
    n-heptanol 235.32
    ethylbenzene 347.23
    MIBK 1038.18
    2-propoxyethanol 561.07
    tert-butanol 712.79
    MTBE 1033.79
    2-butoxyethanol 582.18
    propionic acid 836.49
    o-xylene 541.08
    formic acid 191.28
    diethyl ether 1095.28
    m-xylene 492.49
    p-xylene 551.54
    chlorobenzene 1500.58
    dimethyl carbonate 453.83
    n-octane 30.08
    formamide 528.91
    cyclopentanone 3399.4
    2-pentanone 1756.05
    anisole 670.0
    cyclopentyl methyl ether 1576.33
    gamma-butyrolactone 3246.65
    1-methoxy-2-propanol 795.67
    pyridine 2257.54
    3-pentanone 1338.02
    furfural 2070.55
    n-dodecane 17.35
    diethylene glycol 251.23
    diisopropyl ether 321.31
    tert-amyl alcohol 662.5
    acetylacetone 1633.63
    n-hexadecane 21.21
    acetophenone 876.47
    methyl propionate 1283.69
    isopentyl acetate 954.5
    trichloroethylene 5706.2
    n-nonanol 191.24
    cyclohexanol 1258.85
    benzyl alcohol 513.55
    2-ethylhexanol 265.53
    isooctanol 246.07
    dipropyl ether 528.8
    1,2-dichlorobenzene 1366.69
    ethyl lactate 398.82
    propylene carbonate 1754.0
    n-methylformamide 1105.91
    2-pentanol 527.2
    n-pentane 90.01
    1-propoxy-2-propanol 534.77
    1-methoxy-2-propyl acetate 811.69
    2-(2-methoxypropoxy) propanol 345.15
    mesitylene 311.84
    ε-caprolactone 2728.02
    p-cymene 202.45
    epichlorohydrin 3516.83
    1,1,1-trichloroethane 3301.43
    2-aminoethanol 199.19
    morpholine-4-carbaldehyde 1799.72
    sulfolane 3555.38
    2,2,4-trimethylpentane 69.87
    2-methyltetrahydrofuran 2284.06
    n-hexyl acetate 889.0
    isooctane 36.14
    2-(2-butoxyethoxy)ethanol 550.77
    sec-butyl acetate 895.12
    tert-butyl acetate 1139.65
    decalin 116.92
    glycerin 154.68
    diglyme 1448.9
    acrylic acid 599.6
    isopropyl myristate 239.43
    n-butyric acid 1620.7
    acetyl acetate 982.38
    di(2-ethylhexyl) phthalate 205.24
    ethyl propionate 1145.55
    nitromethane 1944.25
    1,2-diethoxyethane 972.03
    benzonitrile 911.08
    trioctyl phosphate 152.9
    1-bromopropane 2091.87
    gamma-valerolactone 3697.24
    n-decanol 121.99
    triethyl phosphate 330.55
    4-methyl-2-pentanol 287.93
    propionitrile 1075.14
    vinylene carbonate 1388.71
    1,1,2-trichlorotrifluoroethane 1768.59
    DMS 636.86
    cumene 216.2
    2-octanol 204.2
    2-hexanone 1127.42
    octyl acetate 322.15
    limonene 376.21
    1,2-dimethoxyethane 1383.22
    ethyl orthosilicate 334.25
    tributyl phosphate 220.28
    diacetone alcohol 932.81
    N,N-dimethylaniline 411.27
    acrylonitrile 1138.72
    aniline 946.13
    1,3-propanediol 418.26
    bromobenzene 1653.07
    dibromomethane 3274.43
    1,1,2,2-tetrachloroethane 4763.11
    2-methyl-cyclohexyl acetate 592.78
    tetrabutyl urea 315.63
    diisobutyl methanol 171.45
    2-phenylethanol 373.66
    styrene 502.85
    dioctyl adipate 382.29
    dimethyl sulfate 774.52
    ethyl butyrate 880.35
    methyl lactate 415.97
    butyl lactate 613.95
    diethyl carbonate 490.04
    propanediol butyl ether 375.58
    triethyl orthoformate 524.65
    p-tert-butyltoluene 176.29
    methyl 4-tert-butylbenzoate 590.41
    morpholine 2094.52
    tert-butylamine 456.81
    n-dodecanol 86.09
    dimethoxymethane 1038.27
    ethylene carbonate 1416.94
    cyrene 459.38
    2-ethoxyethyl acetate 1133.69
    2-ethylhexyl acetate 759.14
    1,2,4-trichlorobenzene 1547.24
    4-methylpyridine 2150.47
    dibutyl ether 481.38
    2,6-dimethyl-4-heptanol 171.45
    DEF 2063.89
    dimethyl isosorbide 788.65
    tetrachloroethylene 3109.82
    eugenol 477.6
    triacetin 762.21
    span 80 345.96
    1,4-butanediol 161.74
    1,1-dichloroethane 3323.05
    2-methyl-1-pentanol 434.95
    methyl formate 653.58
    2-methyl-1-butanol 713.01
    n-decane 35.78
    butyronitrile 1152.15
    3,7-dimethyl-1-octanol 222.03
    1-chlorooctane 251.87
    1-chlorotetradecane 69.42
    n-nonane 35.26
    undecane 23.06
    tert-butylcyclohexane 77.51
    cyclooctane 87.47
    cyclopentanol 1119.41
    tetrahydropyran 2458.7
    tert-amyl methyl ether 785.74
    2,5,8-trioxanonane 662.65
    1-hexene 351.29
    2-isopropoxyethanol 515.98
    2,2,2-trifluoroethanol 426.3
    methyl butyrate 1692.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction