Myristoyl Sarcosine

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  • Identifiers

    CAS number
    52558-73-3

    Molecular formula
    C17H33NO3

    SMILES
    CCCCCCCCCCCCCC(=O)N(C)CC(=O)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Waxy 43.02%
    Fatty 39.23%
    Odorless 34.14%
    Savory 29.32%
    Milky 28.61%
    Woody 28.12%
    Citrus 27.95%
    Fresh 27.93%
    Oily 27.28%
    Meaty 27.05%

     

    Flavor
    Bland 34.61%
    Mild 33.02%
    Fatty 32.96%
    Odorless 32.59%
    Waxy 28.59%
    Oily 27.62%
    Faint 24.17%
    Slightly waxy 23.03%
    Bay oil 22.36%
    Cultured dairy 21.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.6

    pKa est.
    6.82 (neutral)

    Molecular weight
    299.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    427°C

    Flash point

    • 201.31 ˚C est.

  • Synonyms

    • 52558-73-3
    • N-(1-Oxotetradecyl)sarcosine
    • Myristoyl sarcosine
    • Hamposyl m
    • Glycine, N-methyl-N-(1-oxotetradecyl)-
    • N-Myristoylsarcosine acid
    • n-tetradecanoylsarcosine
    • myristoyl sarcosinate
    • ZL6OI6P595
    • CRODASINIC M
    • Myristoyl N-methylglycine
    • EINECS 258-007-1
    • SARCOSINE, N-MYRISTOYL-
    • DTXSID7068766
    • N-Methyl-N-(1-oxotetradecyl)glycine
    • RefChem:819747
    • DTXCID6041210
    • MYRISTOYL SARCOSINE [INCI]
    • n-methyl-n-tetradecanoylglycine
    • 2-[methyl(tetradecanoyl)amino]acetic acid
    • 2-(N-methyltetradecanamido)acetic acid
    • MFCD00418356
    • UNII-ZL6OI6P595
    • Hamposylm
    • SCHEMBL220222
    • CHEMBL4462773
    • NGOZDSMNMIRDFP-UHFFFAOYSA-N
    • DB-230872
    • CS-0111608
    • NS00013876
    • D76995
    • EN300-6481196
    • Q27295678
    • 52558-73-3

  • Applications

    Myristoyl Sarcosine (CAS 52558-73-3) is used as a mild surfactant and emulsifier in cosmetic and personal care formulations, where it can act as a cleansing and conditioning component for skin and hair. It also appears in household and industrial cleaning products as a surface-active ingredient with emulsifying and wetting properties. In industrial manufacturing, it can serve as an additive, emulsifier or dispersant in polymer systems, coatings and paints, aiding pigment dispersion and formulation stability. It may function as an intermediate in the synthesis of specialty surfactants and related chemicals. Additionally, it can be employed in coatings, inks and adhesives as a dispersant or coupling agent depending on formulation needs and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 137.23
    methanol 246.38
    isopropanol 126.32
    water 0.12
    ethyl acetate 122.02
    n-propanol 118.56
    acetone 149.09
    n-butanol 105.35
    acetonitrile 64.81
    DMF 385.21
    toluene 49.19
    isobutanol 101.29
    1,4-dioxane 161.83
    methyl acetate 108.85
    THF 426.09
    2-butanone 160.04
    n-pentanol 93.78
    sec-butanol 114.86
    n-hexane 5.32
    ethylene glycol 13.83
    NMP 527.61
    cyclohexane 15.44
    DMSO 623.07
    n-butyl acetate 146.95
    n-octanol 36.0
    chloroform 315.3
    n-propyl acetate 177.89
    acetic acid 144.48
    dichloromethane 335.66
    cyclohexanone 438.22
    propylene glycol 41.23
    isopropyl acetate 130.8
    DMAc 566.71
    2-ethoxyethanol 219.6
    isopentanol 124.63
    n-heptane 2.76
    ethyl formate 100.46
    1,2-dichloroethane 275.96
    n-hexanol 59.61
    2-methoxyethanol 256.44
    isobutyl acetate 115.87
    tetrachloromethane 56.9
    n-pentyl acetate 144.02
    transcutol 561.46
    n-heptanol 43.2
    ethylbenzene 38.97
    MIBK 144.18
    2-propoxyethanol 161.76
    tert-butanol 195.95
    MTBE 147.77
    2-butoxyethanol 142.11
    propionic acid 116.32
    o-xylene 55.34
    formic acid 55.48
    diethyl ether 74.79
    m-xylene 45.15
    p-xylene 58.85
    chlorobenzene 90.54
    dimethyl carbonate 39.36
    n-octane 2.17
    formamide 111.98
    cyclopentanone 428.64
    2-pentanone 151.27
    anisole 87.96
    cyclopentyl methyl ether 181.65
    gamma-butyrolactone 421.93
    1-methoxy-2-propanol 219.71
    pyridine 180.23
    3-pentanone 108.46
    furfural 322.45
    n-dodecane 1.69
    diethylene glycol 95.91
    diisopropyl ether 30.37
    tert-amyl alcohol 173.29
    acetylacetone 206.22
    n-hexadecane 2.02
    acetophenone 133.33
    methyl propionate 105.18
    isopentyl acetate 159.15
    trichloroethylene 422.62
    n-nonanol 35.51
    cyclohexanol 147.88
    benzyl alcohol 94.19
    2-ethylhexanol 44.8
    isooctanol 44.01
    dipropyl ether 45.2
    1,2-dichlorobenzene 111.1
    ethyl lactate 80.44
    propylene carbonate 232.25
    n-methylformamide 153.81
    2-pentanol 71.03
    n-pentane 3.71
    1-propoxy-2-propanol 124.55
    1-methoxy-2-propyl acetate 155.27
    2-(2-methoxypropoxy) propanol 119.71
    mesitylene 32.2
    ε-caprolactone 372.94
    p-cymene 26.09
    epichlorohydrin 430.49
    1,1,1-trichloroethane 222.76
    2-aminoethanol 59.83
    morpholine-4-carbaldehyde 365.1
    sulfolane 683.71
    2,2,4-trimethylpentane 6.53
    2-methyltetrahydrofuran 282.74
    n-hexyl acetate 131.55
    isooctane 3.54
    2-(2-butoxyethoxy)ethanol 170.13
    sec-butyl acetate 125.52
    tert-butyl acetate 181.39
    decalin 10.95
    glycerin 67.62
    diglyme 362.56
    acrylic acid 84.52
    isopropyl myristate 37.67
    n-butyric acid 219.05
    acetyl acetate 90.38
    di(2-ethylhexyl) phthalate 49.64
    ethyl propionate 120.42
    nitromethane 260.55
    1,2-diethoxyethane 147.31
    benzonitrile 102.85
    trioctyl phosphate 34.55
    1-bromopropane 118.99
    gamma-valerolactone 597.66
    n-decanol 22.71
    triethyl phosphate 62.01
    4-methyl-2-pentanol 53.15
    propionitrile 75.52
    vinylene carbonate 169.19
    1,1,2-trichlorotrifluoroethane 335.93
    DMS 89.76
    cumene 31.01
    2-octanol 32.85
    2-hexanone 157.21
    octyl acetate 51.02
    limonene 43.32
    1,2-dimethoxyethane 359.16
    ethyl orthosilicate 60.18
    tributyl phosphate 46.86
    diacetone alcohol 224.83
    N,N-dimethylaniline 72.44
    acrylonitrile 90.0
    aniline 76.46
    1,3-propanediol 113.01
    bromobenzene 93.1
    dibromomethane 205.97
    1,1,2,2-tetrachloroethane 441.31
    2-methyl-cyclohexyl acetate 105.91
    tetrabutyl urea 69.59
    diisobutyl methanol 29.42
    2-phenylethanol 75.62
    styrene 45.98
    dioctyl adipate 75.77
    dimethyl sulfate 114.72
    ethyl butyrate 107.93
    methyl lactate 73.59
    butyl lactate 121.38
    diethyl carbonate 63.44
    propanediol butyl ether 118.08
    triethyl orthoformate 82.8
    p-tert-butyltoluene 25.37
    methyl 4-tert-butylbenzoate 122.52
    morpholine 292.86
    tert-butylamine 96.28
    n-dodecanol 15.57
    dimethoxymethane 144.86
    ethylene carbonate 154.71
    cyrene 152.97
    2-ethoxyethyl acetate 177.56
    2-ethylhexyl acetate 114.65
    1,2,4-trichlorobenzene 137.55
    4-methylpyridine 183.6
    dibutyl ether 53.16
    2,6-dimethyl-4-heptanol 29.42
    DEF 243.33
    dimethyl isosorbide 236.49
    tetrachloroethylene 281.11
    eugenol 117.77
    triacetin 146.82
    span 80 103.05
    1,4-butanediol 51.98
    1,1-dichloroethane 200.88
    2-methyl-1-pentanol 102.22
    methyl formate 86.09
    2-methyl-1-butanol 110.02
    n-decane 3.42
    butyronitrile 92.64
    3,7-dimethyl-1-octanol 42.15
    1-chlorooctane 25.34
    1-chlorotetradecane 7.7
    n-nonane 3.05
    undecane 2.24
    tert-butylcyclohexane 8.92
    cyclooctane 3.56
    cyclopentanol 159.74
    tetrahydropyran 222.35
    tert-amyl methyl ether 117.75
    2,5,8-trioxanonane 209.07
    1-hexene 31.86
    2-isopropoxyethanol 157.26
    2,2,2-trifluoroethanol 67.32
    methyl butyrate 215.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction