Myristoyl Glutamic Acid

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  • Identifiers

    CAS number
    53576-52-6

    Molecular formula
    C19H35NO5

    SMILES
    CCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 47.09%
    Savory 36.72%
    Fatty 32.45%
    Meaty 30.32%
    Waxy 26.27%
    Milky 26.21%
    Oily 23.94%
    Cooling 22.21%
    Lactonic 22.02%
    Citrus 20.38%

     

    Flavor
    Odorless 50.28%
    Bland 37.02%
    Mild 36.34%
    Fatty 28.79%
    Faint 24.96%
    Waxy 24.06%
    Bay oil 21.92%
    Slightly waxy 21.75%
    Cultured dairy 21.19%
    Sweet-like 20.61%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    5.68 (weak acid)

    Molecular weight
    357.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    481°C

    Flash point

    • 257.36 ˚C est.

  • Synonyms

    • Myristoyl glutamic acid
    • N-Myristoyl-L-glutamic acid
    • N-Myristoylglutamic acid
    • N-Tetradecanoyl-L-glutamic acid
    • Glutamic acid, N-myristoyl-, l-
    • L-Glutamic acid, N-(1-oxotetradecyl)-
    • UNII-31N1S89X64
    • 31N1S89X64
    • DTXSID40201791
    • RefChem:160423
    • DTXCID70124282
    • MYRISTOYL GLUTAMIC ACID [INCI]
    • 53576-52-6
    • Tetradecanoyl-L-glutamic acid
    • (2S)-2-(tetradecanoylamino)pentanedioic acid
    • starbld0015003
    • SCHEMBL336372
    • orb1695988
    • MTJZWYHTZFVEGI-INIZCTEOSA-N
    • AKOS040753177
    • HY-126460
    • CS-0104637
    • Q27256068
    • 53576-52-6

  • Applications

    Myristoyl Glutamic Acid (CAS 53576-52-6) is an amino acid-derived lipid-modified compound commonly considered an amphiphilic surfactant and emulsifier. Real-world applications include: 1) cosmetics and personal care, as a mild surfactant and emulsifier in creams and cleansers; 2) household products, as a gentle surfactant in cleaners and dishwashing formulations; 3) polymers and plastics, used as a processing aid or compatibilizer to improve emulsification and phase compatibility in polymer blends; 4) coatings and inks, providing stabilization for oil–water systems and aiding pigment dispersion; 5) pharmaceuticals, may serve as an excipient or formulation aid subject to regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 14.4
    methanol 35.43
    isopropanol 8.36
    water 0.39
    ethyl acetate 6.77
    n-propanol 11.24
    acetone 18.96
    n-butanol 7.55
    acetonitrile 3.24
    DMF 164.64
    toluene 2.39
    isobutanol 6.91
    1,4-dioxane 15.19
    methyl acetate 8.8
    THF 54.62
    2-butanone 14.15
    n-pentanol 9.68
    sec-butanol 8.71
    n-hexane 0.58
    ethylene glycol 5.37
    NMP 219.21
    cyclohexane 0.54
    DMSO 289.09
    n-butyl acetate 8.77
    n-octanol 6.07
    chloroform 9.18
    n-propyl acetate 10.72
    acetic acid 34.97
    dichloromethane 10.6
    cyclohexanone 39.74
    propylene glycol 12.32
    isopropyl acetate 8.49
    DMAc 283.13
    2-ethoxyethanol 40.99
    isopentanol 8.11
    n-heptane 0.31
    ethyl formate 8.94
    1,2-dichloroethane 10.01
    n-hexanol 5.5
    2-methoxyethanol 49.71
    isobutyl acetate 7.13
    tetrachloromethane 2.35
    n-pentyl acetate 13.11
    transcutol 125.51
    n-heptanol 6.35
    ethylbenzene 3.17
    MIBK 10.37
    2-propoxyethanol 28.19
    tert-butanol 14.03
    MTBE 8.07
    2-butoxyethanol 27.64
    propionic acid 19.54
    o-xylene 4.59
    formic acid 30.49
    diethyl ether 3.42
    m-xylene 2.95
    p-xylene 4.62
    chlorobenzene 3.6
    dimethyl carbonate 9.85
    n-octane 0.29
    formamide 46.38
    cyclopentanone 56.27
    2-pentanone 11.27
    anisole 8.48
    cyclopentyl methyl ether 15.25
    gamma-butyrolactone 63.63
    1-methoxy-2-propanol 41.55
    pyridine 14.31
    3-pentanone 10.05
    furfural 52.59
    n-dodecane 0.22
    diethylene glycol 24.94
    diisopropyl ether 1.91
    tert-amyl alcohol 16.06
    acetylacetone 25.4
    n-hexadecane 0.25
    acetophenone 17.22
    methyl propionate 11.04
    isopentyl acetate 10.57
    trichloroethylene 19.22
    n-nonanol 6.28
    cyclohexanol 10.94
    benzyl alcohol 11.57
    2-ethylhexanol 3.99
    isooctanol 5.82
    dipropyl ether 4.07
    1,2-dichlorobenzene 5.84
    ethyl lactate 14.41
    propylene carbonate 30.21
    n-methylformamide 38.96
    2-pentanol 4.91
    n-pentane 0.28
    1-propoxy-2-propanol 21.23
    1-methoxy-2-propyl acetate 18.91
    2-(2-methoxypropoxy) propanol 34.98
    mesitylene 2.42
    ε-caprolactone 42.41
    p-cymene 2.59
    epichlorohydrin 38.51
    1,1,1-trichloroethane 7.29
    2-aminoethanol 15.39
    morpholine-4-carbaldehyde 109.88
    sulfolane 193.18
    2,2,4-trimethylpentane 0.55
    2-methyltetrahydrofuran 22.26
    n-hexyl acetate 15.28
    isooctane 0.26
    2-(2-butoxyethoxy)ethanol 44.69
    sec-butyl acetate 8.31
    tert-butyl acetate 15.34
    decalin 0.85
    glycerin 27.61
    diglyme 81.0
    acrylic acid 20.48
    isopropyl myristate 5.08
    n-butyric acid 20.59
    acetyl acetate 7.92
    di(2-ethylhexyl) phthalate 9.95
    ethyl propionate 9.34
    nitromethane 48.5
    1,2-diethoxyethane 17.68
    benzonitrile 7.23
    trioctyl phosphate 6.37
    1-bromopropane 3.51
    gamma-valerolactone 105.61
    n-decanol 4.03
    triethyl phosphate 9.61
    4-methyl-2-pentanol 4.33
    propionitrile 3.58
    vinylene carbonate 22.24
    1,1,2-trichlorotrifluoroethane 64.48
    DMS 15.09
    cumene 3.14
    2-octanol 4.48
    2-hexanone 13.32
    octyl acetate 7.45
    limonene 3.63
    1,2-dimethoxyethane 54.76
    ethyl orthosilicate 9.53
    tributyl phosphate 8.55
    diacetone alcohol 34.86
    N,N-dimethylaniline 11.52
    acrylonitrile 5.98
    aniline 6.03
    1,3-propanediol 18.84
    bromobenzene 3.24
    dibromomethane 5.83
    1,1,2,2-tetrachloroethane 22.75
    2-methyl-cyclohexyl acetate 12.24
    tetrabutyl urea 15.55
    diisobutyl methanol 3.29
    2-phenylethanol 8.6
    styrene 3.14
    dioctyl adipate 12.64
    dimethyl sulfate 42.09
    ethyl butyrate 8.61
    methyl lactate 21.26
    butyl lactate 21.29
    diethyl carbonate 5.97
    propanediol butyl ether 31.52
    triethyl orthoformate 9.89
    p-tert-butyltoluene 2.69
    methyl 4-tert-butylbenzoate 28.71
    morpholine 29.76
    tert-butylamine 5.55
    n-dodecanol 2.65
    dimethoxymethane 33.48
    ethylene carbonate 16.78
    cyrene 46.49
    2-ethoxyethyl acetate 22.26
    2-ethylhexyl acetate 7.93
    1,2,4-trichlorobenzene 8.87
    4-methylpyridine 13.92
    dibutyl ether 5.57
    2,6-dimethyl-4-heptanol 3.29
    DEF 32.75
    dimethyl isosorbide 60.43
    tetrachloroethylene 15.23
    eugenol 27.16
    triacetin 29.19
    span 80 25.95
    1,4-butanediol 10.96
    1,1-dichloroethane 5.47
    2-methyl-1-pentanol 10.64
    methyl formate 21.39
    2-methyl-1-butanol 9.01
    n-decane 0.44
    butyronitrile 4.14
    3,7-dimethyl-1-octanol 5.61
    1-chlorooctane 2.38
    1-chlorotetradecane 0.83
    n-nonane 0.38
    undecane 0.29
    tert-butylcyclohexane 0.73
    cyclooctane 0.27
    cyclopentanol 15.15
    tetrahydropyran 10.57
    tert-amyl methyl ether 10.25
    2,5,8-trioxanonane 58.89
    1-hexene 2.23
    2-isopropoxyethanol 25.84
    2,2,2-trifluoroethanol 19.45
    methyl butyrate 16.37

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction