Myristamidopropyl Hydroxysultaine

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  • Identifiers

    CAS number
    63663-10-5

    Molecular formula
    C22H46N2O5S

    SMILES
    CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(CS(=O)(=O)[O-])O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 47.89%
    Savory 37.01%
    Meaty 32.71%
    Cooling 31.9%
    Fatty 25.06%
    Animal 22.56%
    Fishy 21.7%
    Mint 21.11%
    Citrus 21.04%
    Fresh 20.46%

     

    Flavor
    Bland 37.76%
    Bitter 31.17%
    Odorless 31.03%
    Mild 26.6%
    Cedarleaf 19.75%
    Slightly waxy 19.45%
    Delicate 19.16%
    Faint 18.9%
    Oriental 18.85%
    Bay oil 18.78%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.4

    pKa est.
    5.52 (weak acid)

    Molecular weight
    450.7 g/mol

    Flash point

    • -19.24 ˚C est.

  • Synonyms

    • Obazolin MHS-121
    • Myristamidopropyl hydroxysultaine
    • ASB 14O
    • UNII-CMS3N9J80G
    • CMS3N9J80G
    • 1-Propanaminium, 2-hydroxy-N,N-dimethyl-N-(3-((1-oxotetradecyl)amino)propyl)-3-sulfo-, inner salt
    • 63663-10-5
    • RefChem:160408
    • MYRISTAMIDOPROPYL HYDROXYSULTAINE [INCI]
    • Q27275539
    • 63663-10-5

  • Applications

    Myristamidopropyl Hydroxysultaine, CAS 63663-10-5, is an amphoteric surfactant used widely as a cleansing and conditioning ingredient in cosmetics and personal care formulations. It is also employed in household cleaning products and industrial cleaners as a surfactant to improve spreading, foaming, and soil removal. In polymer and plastics processing it can function as an emulsifier and processing aid to improve dispersion and stability. In coatings and inks it serves as a surfactant to enhance wetting, leveling, and formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.51
    methanol 16.19
    isopropanol 0.77
    water 1.57
    ethyl acetate 1.27
    n-propanol 2.45
    acetone 2.84
    n-butanol 1.43
    acetonitrile 0.91
    DMF 26.9
    toluene 1.2
    isobutanol 1.25
    1,4-dioxane 2.14
    methyl acetate 1.73
    THF 8.41
    2-butanone 2.63
    n-pentanol 1.18
    sec-butanol 1.02
    n-hexane 0.05
    ethylene glycol 3.46
    NMP 150.68
    cyclohexane 0.18
    DMSO 25.5
    n-butyl acetate 1.84
    n-octanol 1.18
    chloroform 9.23
    n-propyl acetate 1.95
    acetic acid 27.96
    dichloromethane 8.74
    cyclohexanone 12.16
    propylene glycol 5.13
    isopropyl acetate 1.05
    DMAc 51.22
    2-ethoxyethanol 7.16
    isopentanol 1.14
    n-heptane 0.07
    ethyl formate 3.25
    1,2-dichloroethane 4.16
    n-hexanol 0.97
    2-methoxyethanol 13.32
    isobutyl acetate 1.36
    tetrachloromethane 1.46
    n-pentyl acetate 3.09
    transcutol 31.38
    n-heptanol 1.45
    ethylbenzene 0.64
    MIBK 1.45
    2-propoxyethanol 7.45
    tert-butanol 0.78
    MTBE 0.37
    2-butoxyethanol 9.22
    propionic acid 8.08
    o-xylene 1.31
    formic acid 44.3
    diethyl ether 0.34
    m-xylene 1.02
    p-xylene 0.83
    chlorobenzene 1.8
    dimethyl carbonate 3.33
    n-octane 0.05
    formamide 41.67
    cyclopentanone 20.78
    2-pentanone 1.89
    anisole 1.53
    cyclopentyl methyl ether 3.76
    gamma-butyrolactone 28.33
    1-methoxy-2-propanol 7.33
    pyridine 6.43
    3-pentanone 2.06
    furfural 33.72
    n-dodecane 0.03
    diethylene glycol 8.31
    diisopropyl ether 0.16
    tert-amyl alcohol 1.24
    acetylacetone 4.55
    n-hexadecane 0.03
    acetophenone 5.17
    methyl propionate 2.94
    isopentyl acetate 2.07
    trichloroethylene 15.58
    n-nonanol 1.19
    cyclohexanol 2.6
    benzyl alcohol 3.52
    2-ethylhexanol 0.82
    isooctanol 1.21
    dipropyl ether 0.69
    1,2-dichlorobenzene 2.99
    ethyl lactate 4.51
    propylene carbonate 13.27
    n-methylformamide 16.01
    2-pentanol 0.56
    n-pentane 0.05
    1-propoxy-2-propanol 5.21
    1-methoxy-2-propyl acetate 4.88
    2-(2-methoxypropoxy) propanol 10.71
    mesitylene 0.58
    ε-caprolactone 15.15
    p-cymene 0.7
    epichlorohydrin 14.4
    1,1,1-trichloroethane 3.07
    2-aminoethanol 7.68
    morpholine-4-carbaldehyde 41.01
    sulfolane 88.0
    2,2,4-trimethylpentane 0.07
    2-methyltetrahydrofuran 3.69
    n-hexyl acetate 3.11
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 12.48
    sec-butyl acetate 1.23
    tert-butyl acetate 1.66
    decalin 0.13
    glycerin 16.72
    diglyme 20.71
    acrylic acid 13.6
    isopropyl myristate 0.77
    n-butyric acid 7.28
    acetyl acetate 1.96
    di(2-ethylhexyl) phthalate 3.09
    ethyl propionate 1.7
    nitromethane 23.95
    1,2-diethoxyethane 1.8
    benzonitrile 2.54
    trioctyl phosphate 1.72
    1-bromopropane 0.96
    gamma-valerolactone 41.96
    n-decanol 0.66
    triethyl phosphate 2.9
    4-methyl-2-pentanol 0.47
    propionitrile 0.94
    vinylene carbonate 13.33
    1,1,2-trichlorotrifluoroethane 48.89
    DMS 3.93
    cumene 0.58
    2-octanol 0.69
    2-hexanone 1.82
    octyl acetate 1.36
    limonene 1.01
    1,2-dimethoxyethane 5.42
    ethyl orthosilicate 2.45
    tributyl phosphate 2.18
    diacetone alcohol 5.62
    N,N-dimethylaniline 2.32
    acrylonitrile 2.37
    aniline 3.07
    1,3-propanediol 5.56
    bromobenzene 1.61
    dibromomethane 3.93
    1,1,2,2-tetrachloroethane 13.18
    2-methyl-cyclohexyl acetate 3.88
    tetrabutyl urea 3.86
    diisobutyl methanol 0.44
    2-phenylethanol 2.97
    styrene 0.69
    dioctyl adipate 2.81
    dimethyl sulfate 16.13
    ethyl butyrate 2.05
    methyl lactate 8.53
    butyl lactate 7.99
    diethyl carbonate 1.67
    propanediol butyl ether 11.19
    triethyl orthoformate 2.56
    p-tert-butyltoluene 0.65
    methyl 4-tert-butylbenzoate 10.5
    morpholine 5.65
    tert-butylamine 0.32
    n-dodecanol 0.39
    dimethoxymethane 5.53
    ethylene carbonate 8.01
    cyrene 24.83
    2-ethoxyethyl acetate 5.47
    2-ethylhexyl acetate 1.74
    1,2,4-trichlorobenzene 4.91
    4-methylpyridine 4.32
    dibutyl ether 0.61
    2,6-dimethyl-4-heptanol 0.44
    DEF 6.79
    dimethyl isosorbide 21.34
    tetrachloroethylene 10.53
    eugenol 11.17
    triacetin 9.73
    span 80 9.06
    1,4-butanediol 2.42
    1,1-dichloroethane 1.96
    2-methyl-1-pentanol 1.19
    methyl formate 9.74
    2-methyl-1-butanol 1.56
    n-decane 0.07
    butyronitrile 0.85
    3,7-dimethyl-1-octanol 0.96
    1-chlorooctane 0.43
    1-chlorotetradecane 0.13
    n-nonane 0.06
    undecane 0.04
    tert-butylcyclohexane 0.08
    cyclooctane 0.08
    cyclopentanol 4.01
    tetrahydropyran 1.88
    tert-amyl methyl ether 0.75
    2,5,8-trioxanonane 14.04
    1-hexene 0.21
    2-isopropoxyethanol 3.46
    2,2,2-trifluoroethanol 16.33
    methyl butyrate 3.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction