Myristamidopropyl Betaine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    59272-84-3

    Molecular formula
    C21H42N2O3

    SMILES
    CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)[O-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Savory 34.06%
    Meaty 33.44%
    Odorless 32.26%
    Cooling 31.79%
    Fatty 29.92%
    Waxy 29.75%
    Animal 28.53%
    Fishy 26.65%
    Mint 24.93%
    Fresh 24.04%

     

    Flavor
    Bland 38.32%
    Odorless 32.17%
    Mild 30.37%
    Herbal 22.8%
    Faint 21.86%
    Slightly waxy 20.8%
    Delicate 19.99%
    Bay oil 19.93%
    Cedarleaf 19.45%
    Carrot 19.05%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    6.4

    pKa est.
    5.02 (weak acid)

    Molecular weight
    370.6 g/mol

    Flash point

    • -51.93 ˚C est.

  • Synonyms

    • 59272-84-3
    • Myristamidopropyl betaine
    • 4V55I1QW8M
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxotetradecyl)amino]-, inner salt
    • SOFTAZOLINE MPB
    • VISTA MAP
    • (carboxymethyl)dimethyl-3-[(1-oxotetradecyl)amino]propylammonium hydroxide
    • ACB 14
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxotetradecyl)amino)-, inner salt
    • (Carboxymethyl)dimethyl-3-((1-oxotetradecyl)amino)propylammonium hydroxide
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxotetradecyl)amino)-, hydroxide, inner salt
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxotetradecyl)amino]-, hydroxide, inner salt
    • RefChem:819727
    • MYRISTAMIDOPROPYL BETAINE [INCI]
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-(1-oxotetradecyl)amino-, inner salt
    • 2-[dimethyl-[3-(tetradecanoylamino)propyl]azaniumyl]acetate
    • Myristoylamide Propylbetaine
    • N-Myristylamidopropyl-N,N-dimethylbetaine
    • EINECS 261-684-6
    • UNII-4V55I1QW8M
    • 3-Myristoylamidopropyl betaine
    • Cocamidopropylbetaine-C14
    • Dimethyl(3-tetradecylamidopropyl)ammonioethanoate
    • SCHEMBL5457760
    • DTXSID9041283
    • Myristamidopropyl dimethyl glycine
    • CHEBI:191137
    • QGCUAFIULMNFPJ-UHFFFAOYSA-N
    • MSK175408-100A
    • N-(Carboxymethyl)-N,N-dimethyl-3-((1-oxotetradecyl)amino)-1-propa- naminium hydroxide, inner salt
    • NS00013872
    • NS00076682
    • [Dimethyl(3-tetradecanamidopropyl)azaniumyl]acetate
    • 2-(dimethyl(3-tetradecanamidopropyl)ammonio)acetate
    • Q27260548
    • Myristoylamide Propylbetaine Solution in Acetonitrile, 100ug/mL
    • Amidopropylalkyl carboxymethyl dimethyl ammonium compound C14 (apAcMDMAC C14)
    • 59272-84-3

  • Applications

    Myristamidopropyl Betaine (CAS 59272-84-3) is a zwitterionic surfactant commonly used in cosmetics and personal care as a mild cleansing and foaming agent, often providing conditioning benefits in shampoos and body washes; it is also employed in household cleaning products such as dish liquids and general cleaners as a gentle surfactant/foam booster; in industrial cleaning formulations it acts as a surfactant to improve wettability and cleaning performance; it can serve as an emulsifier and stabilizer or viscosity modifier in cosmetic emulsions and polymer formulations; in pharmaceutical topical products it is used as an excipient surfactant to aid dispersion and spread on the skin; and in coatings and inks formulations as a wetting/dispersing agent to improve gloss and leveling, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 41.62
    methanol 109.44
    isopropanol 15.46
    water 3.48
    ethyl acetate 14.59
    n-propanol 30.97
    acetone 28.6
    n-butanol 20.61
    acetonitrile 8.1
    DMF 78.99
    toluene 8.2
    isobutanol 19.7
    1,4-dioxane 24.24
    methyl acetate 17.21
    THF 59.22
    2-butanone 24.92
    n-pentanol 16.58
    sec-butanol 17.53
    n-hexane 0.93
    ethylene glycol 18.0
    NMP 209.96
    cyclohexane 2.35
    DMSO 116.7
    n-butyl acetate 16.19
    n-octanol 10.25
    chloroform 85.46
    n-propyl acetate 18.05
    acetic acid 155.36
    dichloromethane 78.26
    cyclohexanone 78.56
    propylene glycol 30.98
    isopropyl acetate 12.13
    DMAc 138.62
    2-ethoxyethanol 52.95
    isopentanol 15.66
    n-heptane 0.62
    ethyl formate 24.13
    1,2-dichloroethane 46.65
    n-hexanol 12.73
    2-methoxyethanol 79.19
    isobutyl acetate 13.04
    tetrachloromethane 16.16
    n-pentyl acetate 23.81
    transcutol 143.44
    n-heptanol 13.4
    ethylbenzene 5.48
    MIBK 14.43
    2-propoxyethanol 45.15
    tert-butanol 16.38
    MTBE 7.52
    2-butoxyethanol 48.49
    propionic acid 54.75
    o-xylene 10.03
    formic acid 131.61
    diethyl ether 5.18
    m-xylene 7.77
    p-xylene 7.35
    chlorobenzene 15.93
    dimethyl carbonate 12.81
    n-octane 0.46
    formamide 129.11
    cyclopentanone 86.47
    2-pentanone 17.96
    anisole 10.52
    cyclopentyl methyl ether 25.27
    gamma-butyrolactone 104.77
    1-methoxy-2-propanol 46.22
    pyridine 36.07
    3-pentanone 16.85
    furfural 105.99
    n-dodecane 0.31
    diethylene glycol 43.73
    diisopropyl ether 2.39
    tert-amyl alcohol 20.61
    acetylacetone 30.86
    n-hexadecane 0.35
    acetophenone 24.71
    methyl propionate 20.03
    isopentyl acetate 17.86
    trichloroethylene 105.44
    n-nonanol 9.98
    cyclohexanol 32.54
    benzyl alcohol 23.31
    2-ethylhexanol 9.16
    isooctanol 11.53
    dipropyl ether 5.65
    1,2-dichlorobenzene 20.73
    ethyl lactate 22.83
    propylene carbonate 58.11
    n-methylformamide 65.79
    2-pentanol 9.69
    n-pentane 0.79
    1-propoxy-2-propanol 30.16
    1-methoxy-2-propyl acetate 28.27
    2-(2-methoxypropoxy) propanol 40.28
    mesitylene 5.32
    ε-caprolactone 80.83
    p-cymene 5.23
    epichlorohydrin 85.28
    1,1,1-trichloroethane 31.89
    2-aminoethanol 44.52
    morpholine-4-carbaldehyde 102.33
    sulfolane 220.2
    2,2,4-trimethylpentane 1.11
    2-methyltetrahydrofuran 35.34
    n-hexyl acetate 23.84
    isooctane 0.48
    2-(2-butoxyethoxy)ethanol 54.63
    sec-butyl acetate 12.0
    tert-butyl acetate 16.79
    decalin 1.48
    glycerin 62.52
    diglyme 93.4
    acrylic acid 62.84
    isopropyl myristate 6.39
    n-butyric acid 59.31
    acetyl acetate 17.56
    di(2-ethylhexyl) phthalate 16.15
    ethyl propionate 14.47
    nitromethane 105.02
    1,2-diethoxyethane 15.49
    benzonitrile 17.12
    trioctyl phosphate 10.48
    1-bromopropane 14.4
    gamma-valerolactone 139.64
    n-decanol 6.05
    triethyl phosphate 14.46
    4-methyl-2-pentanol 7.11
    propionitrile 9.12
    vinylene carbonate 53.23
    1,1,2-trichlorotrifluoroethane 165.12
    DMS 21.85
    cumene 5.13
    2-octanol 7.45
    2-hexanone 16.83
    octyl acetate 10.44
    limonene 7.44
    1,2-dimethoxyethane 42.66
    ethyl orthosilicate 13.56
    tributyl phosphate 12.79
    diacetone alcohol 36.81
    N,N-dimethylaniline 11.2
    acrylonitrile 15.96
    aniline 20.48
    1,3-propanediol 45.82
    bromobenzene 12.74
    dibromomethane 42.06
    1,1,2,2-tetrachloroethane 98.31
    2-methyl-cyclohexyl acetate 21.62
    tetrabutyl urea 17.87
    diisobutyl methanol 4.73
    2-phenylethanol 19.92
    styrene 5.54
    dioctyl adipate 17.03
    dimethyl sulfate 40.92
    ethyl butyrate 14.3
    methyl lactate 30.95
    butyl lactate 35.24
    diethyl carbonate 10.88
    propanediol butyl ether 48.28
    triethyl orthoformate 15.43
    p-tert-butyltoluene 4.99
    methyl 4-tert-butylbenzoate 38.44
    morpholine 49.17
    tert-butylamine 7.42
    n-dodecanol 3.75
    dimethoxymethane 28.44
    ethylene carbonate 41.43
    cyrene 61.63
    2-ethoxyethyl acetate 35.35
    2-ethylhexyl acetate 14.81
    1,2,4-trichlorobenzene 30.42
    4-methylpyridine 26.13
    dibutyl ether 5.73
    2,6-dimethyl-4-heptanol 4.73
    DEF 35.55
    dimethyl isosorbide 62.68
    tetrachloroethylene 80.83
    eugenol 38.73
    triacetin 44.37
    span 80 37.31
    1,4-butanediol 21.99
    1,1-dichloroethane 25.82
    2-methyl-1-pentanol 16.12
    methyl formate 42.93
    2-methyl-1-butanol 20.15
    n-decane 0.64
    butyronitrile 9.34
    3,7-dimethyl-1-octanol 8.97
    1-chlorooctane 4.43
    1-chlorotetradecane 1.26
    n-nonane 0.56
    undecane 0.42
    tert-butylcyclohexane 1.14
    cyclooctane 0.8
    cyclopentanol 37.46
    tetrahydropyran 23.95
    tert-amyl methyl ether 10.21
    2,5,8-trioxanonane 59.95
    1-hexene 3.52
    2-isopropoxyethanol 31.04
    2,2,2-trifluoroethanol 85.47
    methyl butyrate 22.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction