Myristamidobutyl guanidine acetate

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  • Identifiers

    CAS number
    499222-92-3

    Molecular formula
    C21H44N4O3

    SMILES
    CCCCCCCCCCCCCC(=O)NCCCCN=C(N)N.CC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fishy 45.7%
    Meaty 41.24%
    Savory 36.55%
    Odorless 31.67%
    Cooling 31.55%
    Cheesy 30.25%
    Animal 28.51%
    Ripe 23.04%
    Fresh 22.49%
    Fatty 21.11%

     

    Flavor
    Odorless 31.3%
    Bland 30.97%
    Mild 28.14%
    Faint 23.84%
    Herbal 23.53%
    Slightly waxy 21.1%
    Delicate 20.23%
    Bay oil 20.04%
    Skunky 19.43%
    Cedarleaf 19.31%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.32 (weak base)

    Molecular weight
    400.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    496°C

    Flash point

    • 203.51 ˚C est.

  • Synonyms

    • myristamidobutyl guanidine acetate
    • 2XGY9B4K9U
    • 4-Guanidinobutylmyristoylamide acetate
    • UNII-2XGY9B4K9U
    • 499222-92-3
    • Myristamidobutyl guanidine acetate [INCI]
    • Tetradecanamide, N-(4-((aminoiminomethyl)amino)butyl)-, monoacetate
    • SCHEMBL2906531
    • Q27255761
    • 499222-92-3

  • Applications

    Myristamidobutyl guanidine acetate (CAS number: 499222-92-3) is typically used as a cationic surfactant and conditioning agent in cosmetic and personal care formulations, helping stabilize emulsions and improve product texture. It can function as a surfactant and formulation aid in household cleaning products and detergents, contributing to foam, wetting, and cleaning performance. In industrial manufacturing, it serves as a processing aid, surfactant, and adhesion promoter in coatings and inks, aiding pigment dispersion and film formation. It is also employed as an intermediate or building block for the synthesis of guanidine-containing polymers and specialty surfactants, enabling functionalization of plastics and elastomer matrices.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.74
    methanol 16.98
    isopropanol 3.16
    water 0.28
    ethyl acetate 3.32
    n-propanol 5.2
    acetone 6.09
    n-butanol 4.9
    acetonitrile 1.73
    DMF 24.81
    toluene 2.83
    isobutanol 3.9
    1,4-dioxane 5.78
    methyl acetate 3.28
    THF 25.81
    2-butanone 6.23
    n-pentanol 5.52
    sec-butanol 3.59
    n-hexane 0.46
    ethylene glycol 2.13
    NMP 61.07
    cyclohexane 0.7
    DMSO 64.85
    n-butyl acetate 6.03
    n-octanol 3.32
    chloroform 28.41
    n-propyl acetate 7.26
    acetic acid 22.61
    dichloromethane 24.45
    cyclohexanone 24.3
    propylene glycol 4.84
    isopropyl acetate 3.76
    DMAc 52.16
    2-ethoxyethanol 17.38
    isopentanol 4.87
    n-heptane 0.32
    ethyl formate 6.55
    1,2-dichloroethane 11.6
    n-hexanol 3.76
    2-methoxyethanol 19.61
    isobutyl acetate 5.6
    tetrachloromethane 5.25
    n-pentyl acetate 7.68
    transcutol 52.73
    n-heptanol 4.23
    ethylbenzene 2.23
    MIBK 5.14
    2-propoxyethanol 14.3
    tert-butanol 3.56
    MTBE 2.28
    2-butoxyethanol 16.44
    propionic acid 9.66
    o-xylene 2.93
    formic acid 17.85
    diethyl ether 1.4
    m-xylene 2.36
    p-xylene 3.51
    chlorobenzene 5.96
    dimethyl carbonate 3.36
    n-octane 0.2
    formamide 19.43
    cyclopentanone 31.33
    2-pentanone 5.3
    anisole 4.66
    cyclopentyl methyl ether 8.73
    gamma-butyrolactone 32.95
    1-methoxy-2-propanol 14.69
    pyridine 12.56
    3-pentanone 4.7
    furfural 38.73
    n-dodecane 0.14
    diethylene glycol 10.63
    diisopropyl ether 0.74
    tert-amyl alcohol 4.74
    acetylacetone 9.96
    n-hexadecane 0.16
    acetophenone 10.36
    methyl propionate 4.39
    isopentyl acetate 6.84
    trichloroethylene 30.54
    n-nonanol 3.65
    cyclohexanol 6.94
    benzyl alcohol 8.19
    2-ethylhexanol 3.06
    isooctanol 3.76
    dipropyl ether 2.66
    1,2-dichlorobenzene 7.87
    ethyl lactate 7.97
    propylene carbonate 19.66
    n-methylformamide 12.93
    2-pentanol 2.54
    n-pentane 0.25
    1-propoxy-2-propanol 11.16
    1-methoxy-2-propyl acetate 10.13
    2-(2-methoxypropoxy) propanol 15.54
    mesitylene 1.73
    ε-caprolactone 22.41
    p-cymene 1.95
    epichlorohydrin 26.31
    1,1,1-trichloroethane 10.07
    2-aminoethanol 6.4
    morpholine-4-carbaldehyde 32.68
    sulfolane 79.34
    2,2,4-trimethylpentane 0.33
    2-methyltetrahydrofuran 10.7
    n-hexyl acetate 7.73
    isooctane 0.16
    2-(2-butoxyethoxy)ethanol 19.83
    sec-butyl acetate 4.8
    tert-butyl acetate 5.84
    decalin 0.57
    glycerin 12.33
    diglyme 38.97
    acrylic acid 10.73
    isopropyl myristate 2.57
    n-butyric acid 15.55
    acetyl acetate 4.81
    di(2-ethylhexyl) phthalate 6.13
    ethyl propionate 4.92
    nitromethane 21.1
    1,2-diethoxyethane 7.19
    benzonitrile 6.43
    trioctyl phosphate 3.85
    1-bromopropane 4.13
    gamma-valerolactone 48.78
    n-decanol 2.31
    triethyl phosphate 6.36
    4-methyl-2-pentanol 2.29
    propionitrile 2.19
    vinylene carbonate 16.04
    1,1,2-trichlorotrifluoroethane 52.3
    DMS 5.9
    cumene 2.16
    2-octanol 2.44
    2-hexanone 7.44
    octyl acetate 3.88
    limonene 2.52
    1,2-dimethoxyethane 20.53
    ethyl orthosilicate 6.49
    tributyl phosphate 5.17
    diacetone alcohol 12.21
    N,N-dimethylaniline 5.24
    acrylonitrile 3.47
    aniline 6.43
    1,3-propanediol 9.2
    bromobenzene 5.45
    dibromomethane 12.76
    1,1,2,2-tetrachloroethane 30.74
    2-methyl-cyclohexyl acetate 8.97
    tetrabutyl urea 7.32
    diisobutyl methanol 1.85
    2-phenylethanol 6.9
    styrene 2.64
    dioctyl adipate 6.35
    dimethyl sulfate 13.29
    ethyl butyrate 6.11
    methyl lactate 9.14
    butyl lactate 12.01
    diethyl carbonate 4.49
    propanediol butyl ether 16.38
    triethyl orthoformate 7.25
    p-tert-butyltoluene 1.79
    methyl 4-tert-butylbenzoate 13.99
    morpholine 12.69
    tert-butylamine 1.8
    n-dodecanol 1.46
    dimethoxymethane 9.54
    ethylene carbonate 11.98
    cyrene 23.71
    2-ethoxyethyl acetate 11.24
    2-ethylhexyl acetate 5.67
    1,2,4-trichlorobenzene 11.42
    4-methylpyridine 10.07
    dibutyl ether 2.73
    2,6-dimethyl-4-heptanol 1.85
    DEF 11.48
    dimethyl isosorbide 28.75
    tetrachloroethylene 23.05
    eugenol 14.78
    triacetin 14.6
    span 80 13.13
    1,4-butanediol 4.7
    1,1-dichloroethane 7.13
    2-methyl-1-pentanol 5.65
    methyl formate 8.94
    2-methyl-1-butanol 4.86
    n-decane 0.29
    butyronitrile 3.12
    3,7-dimethyl-1-octanol 3.03
    1-chlorooctane 1.64
    1-chlorotetradecane 0.53
    n-nonane 0.25
    undecane 0.19
    tert-butylcyclohexane 0.44
    cyclooctane 0.28
    cyclopentanol 9.12
    tetrahydropyran 7.23
    tert-amyl methyl ether 3.1
    2,5,8-trioxanonane 25.0
    1-hexene 1.6
    2-isopropoxyethanol 11.02
    2,2,2-trifluoroethanol 13.16
    methyl butyrate 8.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction