Muzanzagenin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    197080-19-6

    Molecular formula
    C27H38O5

    SMILES
    C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3([C@H](C[C@H]5C4=CCC6=CC(=O)[C@H](C[C@]56C)O)O)C)C)OC1

    Safety labels

  • Odor profile

    Fragrance
    Woody 48.72%
    Spicy 40.61%
    Sweet 27.49%
    Mint 26.27%
    Odorless 26.15%
    Herbal 24.33%
    Earthy 22.13%
    Balsamic 21.5%
    Camphoreous 21.4%
    Warm 20.87%

     

    Flavor
    Bitter 77.6%
    Fatty 29.14%
    Cedarleaf 22.83%
    Sweet-like 21.43%
    Ripe apricot 20.52%
    Alkaline 20.46%
    Beet 20.44%
    Soil 20.32%
    Lovage 20.28%
    Patchouli 20.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.9

    pKa est.
    5.12 (weak acid)

    Molecular weight
    442.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    97°C

    Flash point

    • 229.73 ˚C est.

  • Synonyms

    • Muzanzagenin
    • (2S,4S,5'R,6R,7S,8R,9S,10S,12S,13R,15S)-10,15-dihydroxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-1(20),17-diene-6,2'-oxane]-16-one
    • (2S,4S,5'R,6R,7S,8R,9S,10S,12S,13R,15S)-10,15-dihydroxy-5',7,9,13-tetramethylspiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icosa-1(20),17-diene-6,2'-oxane)-16-one
    • RefChem:926275
    • 2beta,12alpha-dihydroxy-(25R)-spirosta-4,7-dien-3-one
    • 197080-19-6
    • CHEMBL455616
    • (25R)-2beta,12alpha-Dihydroxyspirosta-4,7-dien-3-one
    • SCHEMBL31314497
    • CHEBI:175562
    • DTXSID201228514
    • AT41649
    • (2I(2),12I+/-,25R)-2,12-Dihydroxyspirosta-4,7-dien-3-one
    • 197080-19-6

  • Applications

    Muzanzagenin (CAS 197080-19-6) is typically evaluated for use as a fragrance ingredient and odorant in perfumery and cosmetics, contributing to scent profiles and formulation character. It is also considered for inclusion in household products such as cleaners and air fresheners as a fragrance component. In industrial applications, it may serve as a specialty additive or stabilizer in coatings, inks, and polymer formulations. Additionally, it is commonly explored as an intermediate in organic synthesis for pharmaceutical or agrochemical compounds, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.55
    methanol 14.59
    isopropanol 3.15
    water 0.17
    ethyl acetate 6.85
    n-propanol 5.96
    acetone 15.96
    n-butanol 5.92
    acetonitrile 9.45
    DMF 33.58
    toluene 6.32
    isobutanol 3.26
    1,4-dioxane 21.57
    methyl acetate 6.14
    THF 36.99
    2-butanone 9.76
    n-pentanol 5.58
    sec-butanol 1.03
    n-hexane 0.12
    ethylene glycol 2.85
    NMP 25.19
    cyclohexane 0.25
    DMSO 33.4
    n-butyl acetate 7.02
    n-octanol 3.77
    chloroform 25.5
    n-propyl acetate 6.19
    acetic acid 18.26
    dichloromethane 16.01
    cyclohexanone 23.81
    propylene glycol 1.71
    isopropyl acetate 6.84
    DMAc 30.8
    2-ethoxyethanol 18.98
    isopentanol 4.88
    n-heptane 0.16
    ethyl formate 7.09
    1,2-dichloroethane 8.94
    n-hexanol 6.5
    2-methoxyethanol 27.18
    isobutyl acetate 6.17
    tetrachloromethane 3.64
    n-pentyl acetate 10.29
    transcutol 30.72
    n-heptanol 6.56
    ethylbenzene 2.69
    MIBK 9.06
    2-propoxyethanol 33.42
    tert-butanol 2.3
    MTBE 1.59
    2-butoxyethanol 24.23
    propionic acid 5.88
    o-xylene 3.46
    formic acid 12.27
    diethyl ether 3.53
    m-xylene 4.6
    p-xylene 3.55
    chlorobenzene 9.05
    dimethyl carbonate 10.22
    n-octane 0.1
    formamide 17.21
    cyclopentanone 29.42
    2-pentanone 10.2
    anisole 7.93
    cyclopentyl methyl ether 8.82
    gamma-butyrolactone 26.21
    1-methoxy-2-propanol 18.79
    pyridine 23.05
    3-pentanone 7.55
    furfural 27.91
    n-dodecane 0.1
    diethylene glycol 24.83
    diisopropyl ether 1.22
    tert-amyl alcohol 1.0
    acetylacetone 16.81
    n-hexadecane 0.13
    acetophenone 11.81
    methyl propionate 8.34
    isopentyl acetate 8.21
    trichloroethylene 23.31
    n-nonanol 4.78
    cyclohexanol 3.12
    benzyl alcohol 11.34
    2-ethylhexanol 3.36
    isooctanol 5.21
    dipropyl ether 3.25
    1,2-dichlorobenzene 8.39
    ethyl lactate 6.81
    propylene carbonate 12.33
    n-methylformamide 18.66
    2-pentanol 1.75
    n-pentane 0.13
    1-propoxy-2-propanol 16.32
    1-methoxy-2-propyl acetate 15.68
    2-(2-methoxypropoxy) propanol 15.19
    mesitylene 2.43
    ε-caprolactone 16.94
    p-cymene 2.19
    epichlorohydrin 29.47
    1,1,1-trichloroethane 7.06
    2-aminoethanol 5.86
    morpholine-4-carbaldehyde 43.93
    sulfolane 30.23
    2,2,4-trimethylpentane 0.09
    2-methyltetrahydrofuran 7.05
    n-hexyl acetate 10.07
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 21.81
    sec-butyl acetate 4.25
    tert-butyl acetate 6.92
    decalin 0.26
    glycerin 6.96
    diglyme 35.91
    acrylic acid 9.03
    isopropyl myristate 3.77
    n-butyric acid 12.3
    acetyl acetate 9.66
    di(2-ethylhexyl) phthalate 7.73
    ethyl propionate 5.47
    nitromethane 31.04
    1,2-diethoxyethane 7.46
    benzonitrile 12.2
    trioctyl phosphate 5.26
    1-bromopropane 2.82
    gamma-valerolactone 58.34
    n-decanol 2.84
    triethyl phosphate 4.52
    4-methyl-2-pentanol 2.44
    propionitrile 7.92
    vinylene carbonate 18.19
    1,1,2-trichlorotrifluoroethane 25.02
    DMS 8.81
    cumene 2.02
    2-octanol 2.42
    2-hexanone 7.56
    octyl acetate 5.44
    limonene 2.08
    1,2-dimethoxyethane 23.69
    ethyl orthosilicate 4.48
    tributyl phosphate 4.45
    diacetone alcohol 10.98
    N,N-dimethylaniline 6.09
    acrylonitrile 14.38
    aniline 8.89
    1,3-propanediol 12.17
    bromobenzene 7.91
    dibromomethane 9.34
    1,1,2,2-tetrachloroethane 15.63
    2-methyl-cyclohexyl acetate 7.95
    tetrabutyl urea 7.11
    diisobutyl methanol 2.11
    2-phenylethanol 15.58
    styrene 3.11
    dioctyl adipate 7.52
    dimethyl sulfate 14.3
    ethyl butyrate 5.82
    methyl lactate 10.04
    butyl lactate 11.33
    diethyl carbonate 4.36
    propanediol butyl ether 13.95
    triethyl orthoformate 5.96
    p-tert-butyltoluene 1.93
    methyl 4-tert-butylbenzoate 14.55
    morpholine 21.15
    tert-butylamine 0.98
    n-dodecanol 1.65
    dimethoxymethane 30.81
    ethylene carbonate 15.02
    cyrene 20.07
    2-ethoxyethyl acetate 17.02
    2-ethylhexyl acetate 6.11
    1,2,4-trichlorobenzene 10.91
    4-methylpyridine 16.85
    dibutyl ether 2.16
    2,6-dimethyl-4-heptanol 2.11
    DEF 10.69
    dimethyl isosorbide 24.66
    tetrachloroethylene 13.03
    eugenol 18.25
    triacetin 12.97
    span 80 12.65
    1,4-butanediol 5.59
    1,1-dichloroethane 6.01
    2-methyl-1-pentanol 3.88
    methyl formate 13.13
    2-methyl-1-butanol 2.82
    n-decane 0.22
    butyronitrile 7.23
    3,7-dimethyl-1-octanol 3.16
    1-chlorooctane 1.26
    1-chlorotetradecane 0.44
    n-nonane 0.16
    undecane 0.14
    tert-butylcyclohexane 0.19
    cyclooctane 0.14
    cyclopentanol 3.64
    tetrahydropyran 9.06
    tert-amyl methyl ether 1.31
    2,5,8-trioxanonane 24.16
    1-hexene 0.66
    2-isopropoxyethanol 11.38
    2,2,2-trifluoroethanol 8.93
    methyl butyrate 7.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction