Muscogene

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  • Identifiers

    CAS number
    40785-62-4

    Molecular formula
    C14H24O

    SMILES
    C1CCCCC2COCC2/C=C\CCC1

  • Odor profile

    Fragrance
    Musk 63.61%
    Woody 52.94%
    Animal 50.72%
    Amber 50.65%
    Dry 48.31%
    Natural 35.54%
    Earthy 33.53%
    Powdery 31.82%
    Cedar 31.79%
    Warm 29.18%

     

    Flavor
    Animal 39.69%
    Ammoniacal 28.52%
    Alkaline 24.13%
    Shrimp 24.06%
    Amine 20.7%
    Beet 20.2%
    Soil 20.1%
    Cauliflower 19.49%
    Cereal 19.21%
    Terpentine 19.06%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    4.7

    pKa est.
    8.36 (weak base)

    Molecular weight
    208.34 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    287°C

    Flash point

    • 124.1 ˚C est.

  • Synonyms

    • Muscogene
    • 40785-62-4
    • 1,3,3a,4,5,6,7,8,9,10,11,13a-dodecahydrocyclododeca[c]furan
    • EINECS 255-080-1
    • 3-Oxabicyclo(10.3.0)pentadecene-(6)
    • 14-Oxa-bicyclo(10.3.0)-2-pentadecene
    • (4Z)-1,3,3a,6,7,8,9,10,11,12,13,13a-dodecahydrocyclododeca[c]furan
    • 3-oxabicyclo(10.3.0)pentadec-6-ene
    • Cyclododeca(c)furan, 1,3,3a,4,5,6,7,8,9,10,11,13a-dodecahydro-
    • Cyclododeca[c]furan, 1,3,3a,4,5,6,7,8,9,10,11,13a-dodecahydro-
    • DTXSID30866015
    • 1,3,3a,4,5,6,7,8,9,10,11,13a-Dodecahydrocyclododeca(c)furan
    • SCHEMBL3506559
    • 1H,3H,3AH,4H,5H,6H,7H,8H,9H,10H,11H,13AH-CYCLODODECA[C]FURAN
    • DTXCID501476453
    • NS00012350

  • Applications

    Muscogene (CAS 40785-62-4) is primarily used as a fragrance ingredient and odor fixative in perfumery, helping to extend and stabilize musk notes. It is also employed in cosmetics and personal care formulations as a fragrance component to help maintain the scent on skin and hair. In household products such as cleaners and laundry products, it may serve as an odorant or scent additive. In coatings, inks, and other coatings-related applications, it can be used as a fragrance additive to enhance odor perception. It may also be considered as an intermediate in organic synthesis or fragrance-related chemical production. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1453.61
    methanol 857.0
    isopropanol 1298.46
    water 0.22
    ethyl acetate 2067.91
    n-propanol 1565.0
    acetone 1862.7
    n-butanol 1501.89
    acetonitrile 1316.77
    DMF 1142.86
    toluene 2146.15
    isobutanol 1179.08
    1,4-dioxane 3112.18
    methyl acetate 1462.12
    THF 3861.48
    2-butanone 1700.68
    n-pentanol 877.09
    sec-butanol 1175.67
    n-hexane 566.81
    ethylene glycol 217.28
    NMP 1135.9
    cyclohexane 1435.67
    DMSO 1685.44
    n-butyl acetate 1608.77
    n-octanol 474.78
    chloroform 6082.42
    n-propyl acetate 1290.63
    acetic acid 1081.67
    dichloromethane 5236.26
    cyclohexanone 2647.34
    propylene glycol 387.53
    isopropyl acetate 1349.41
    DMAc 911.99
    2-ethoxyethanol 1083.41
    isopentanol 1270.27
    n-heptane 502.4
    ethyl formate 1145.05
    1,2-dichloroethane 3136.81
    n-hexanol 1095.96
    2-methoxyethanol 1411.64
    isobutyl acetate 866.81
    tetrachloromethane 1322.84
    n-pentyl acetate 997.59
    transcutol 3611.24
    n-heptanol 533.51
    ethylbenzene 799.53
    MIBK 1030.79
    2-propoxyethanol 1334.83
    tert-butanol 1219.78
    MTBE 1506.71
    2-butoxyethanol 836.82
    propionic acid 1056.27
    o-xylene 918.14
    formic acid 215.75
    diethyl ether 2451.66
    m-xylene 1100.51
    p-xylene 839.93
    chlorobenzene 2042.52
    dimethyl carbonate 576.08
    n-octane 165.24
    formamide 320.72
    cyclopentanone 2581.6
    2-pentanone 1614.68
    anisole 1089.16
    cyclopentyl methyl ether 2158.9
    gamma-butyrolactone 2568.7
    1-methoxy-2-propanol 1271.44
    pyridine 3054.71
    3-pentanone 1353.03
    furfural 1989.88
    n-dodecane 104.85
    diethylene glycol 774.86
    diisopropyl ether 811.06
    tert-amyl alcohol 965.32
    acetylacetone 1443.61
    n-hexadecane 123.39
    acetophenone 873.54
    methyl propionate 1360.88
    isopentyl acetate 1324.67
    trichloroethylene 4866.95
    n-nonanol 426.5
    cyclohexanol 1682.96
    benzyl alcohol 829.63
    2-ethylhexanol 765.56
    isooctanol 484.0
    dipropyl ether 1295.66
    1,2-dichlorobenzene 1557.55
    ethyl lactate 484.31
    propylene carbonate 1673.36
    n-methylformamide 785.07
    2-pentanol 1102.25
    n-pentane 681.69
    1-propoxy-2-propanol 1112.21
    1-methoxy-2-propyl acetate 1221.98
    2-(2-methoxypropoxy) propanol 680.43
    mesitylene 735.31
    ε-caprolactone 2116.86
    p-cymene 535.93
    epichlorohydrin 2962.64
    1,1,1-trichloroethane 2875.06
    2-aminoethanol 482.54
    morpholine-4-carbaldehyde 1407.9
    sulfolane 2298.25
    2,2,4-trimethylpentane 224.75
    2-methyltetrahydrofuran 3078.98
    n-hexyl acetate 1112.33
    isooctane 237.22
    2-(2-butoxyethoxy)ethanol 989.89
    sec-butyl acetate 896.22
    tert-butyl acetate 1189.24
    decalin 397.18
    glycerin 457.11
    diglyme 1986.19
    acrylic acid 845.96
    isopropyl myristate 459.16
    n-butyric acid 1844.16
    acetyl acetate 1251.86
    di(2-ethylhexyl) phthalate 358.59
    ethyl propionate 1052.77
    nitromethane 1458.0
    1,2-diethoxyethane 1775.46
    benzonitrile 1381.25
    trioctyl phosphate 294.73
    1-bromopropane 2594.18
    gamma-valerolactone 2428.97
    n-decanol 316.22
    triethyl phosphate 459.23
    4-methyl-2-pentanol 675.55
    propionitrile 1490.76
    vinylene carbonate 1525.64
    1,1,2-trichlorotrifluoroethane 1694.62
    DMS 754.46
    cumene 510.41
    2-octanol 377.35
    2-hexanone 1014.63
    octyl acetate 508.2
    limonene 774.84
    1,2-dimethoxyethane 1784.11
    ethyl orthosilicate 489.5
    tributyl phosphate 374.51
    diacetone alcohol 892.63
    N,N-dimethylaniline 640.02
    acrylonitrile 1447.99
    aniline 1568.65
    1,3-propanediol 850.71
    bromobenzene 2481.64
    dibromomethane 3947.61
    1,1,2,2-tetrachloroethane 3802.08
    2-methyl-cyclohexyl acetate 781.62
    tetrabutyl urea 410.29
    diisobutyl methanol 522.56
    2-phenylethanol 793.72
    styrene 1079.34
    dioctyl adipate 592.62
    dimethyl sulfate 657.64
    ethyl butyrate 1178.23
    methyl lactate 549.15
    butyl lactate 628.5
    diethyl carbonate 764.09
    propanediol butyl ether 670.31
    triethyl orthoformate 855.0
    p-tert-butyltoluene 487.5
    methyl 4-tert-butylbenzoate 701.99
    morpholine 3176.79
    tert-butylamine 999.6
    n-dodecanol 254.47
    dimethoxymethane 1388.68
    ethylene carbonate 1523.39
    cyrene 562.35
    2-ethoxyethyl acetate 1207.02
    2-ethylhexyl acetate 1155.36
    1,2,4-trichlorobenzene 1646.06
    4-methylpyridine 2452.0
    dibutyl ether 993.25
    2,6-dimethyl-4-heptanol 522.56
    DEF 1345.08
    dimethyl isosorbide 1073.24
    tetrachloroethylene 2673.44
    eugenol 589.6
    triacetin 952.95
    span 80 675.56
    1,4-butanediol 368.5
    1,1-dichloroethane 3107.44
    2-methyl-1-pentanol 788.29
    methyl formate 660.6
    2-methyl-1-butanol 1138.82
    n-decane 182.69
    butyronitrile 1675.66
    3,7-dimethyl-1-octanol 546.06
    1-chlorooctane 544.88
    1-chlorotetradecane 232.65
    n-nonane 202.0
    undecane 130.51
    tert-butylcyclohexane 284.48
    cyclooctane 553.33
    cyclopentanol 1462.54
    tetrahydropyran 4179.23
    tert-amyl methyl ether 989.1
    2,5,8-trioxanonane 1112.17
    1-hexene 1104.22
    2-isopropoxyethanol 809.0
    2,2,2-trifluoroethanol 399.4
    methyl butyrate 1337.9

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction