Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate (1:1)

Overview IFRA Request a quote

  • Identifiers

    CAS number
    78-21-7

    Molecular formula
    C24H51NO5S

    SMILES
    CCCCCCCCCCCCCCCC[N+]1(CCOCC1)CC.CCOS(=O)(=O)[O-]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Waxy 68.78%
    Fatty 53.48%
    Oily 40.47%
    Meaty 24.37%
    Sweet 23.45%
    Fresh 22.83%
    Clean 21.91%
    Creamy 21.23%
    Savory 20.76%
    Fishy 20.46%

     

    Flavor
    Waxy 44.21%
    Alkane 28.47%
    Fatty 28.46%
    Mild 27.55%
    Bland 24.92%
    Slightly waxy 23.58%
    Delicate 22.17%
    Bay oil 21.33%
    Faint 21.18%
    Beer 21.03%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.8 (neutral)

    Molecular weight
    465.7 g/mol

    Flash point

    • 216.51 ˚C est.

  • Synonyms

    • 78-21-7
    • Quaternium-25
    • Atlas G 263
    • Cetethyl morpholinium ethosulfate
    • Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate
    • N-Cetyl-N-ethylmorpholinium ethyl sulfate
    • G 251
    • G 263
    • G-263
    • 4-Ethyl-4-hexadecylmorpholinium ethyl sulfate
    • 4-Ethyl-4-hexadecyl morpholinium ethyl sulfate
    • Cetyl ethyl morpholinium ethosulfate
    • FU19SYM476
    • BARQUAT CME
    • NSC-215231
    • Sulfuric acid, monoethyl ester, ion(1-), 4-ethyl-4-hexadecylmorpholinium
    • Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate (1:1)
    • G-251
    • RefChem:124690
    • 201-094-8
    • Barquat cme-A
    • CETYLETHYLMORPHOLINIUM ETHOSULFATE
    • N-Cetyl-N-ethylmorpholinium ethosulfate
    • N-Cetyl-N-ethylmorpholinium ethylsulfate
    • Ethyl-N-hexadecylmorpholinium ethosulfate
    • N-Hexadecyl-N-ethylmorpholinium ethyl sulfate
    • 4-ethyl-4-hexadecylmorpholin-4-ium;ethyl sulfate
    • Caswell No. 165F
    • G 251 (VAN)
    • EINECS 201-094-8
    • EPA Pesticide Chemical Code 069187
    • NSC 215231
    • UNII-FU19SYM476
    • 4-Ethyl-4-hexadecylmorpholinium ethyl sulphate
    • Atlas G-263
    • N-Cetyl-N-ethyl morpholinium ethyl sulfate
    • 4-Ethyl-4-hexadecylmorpholinium, ethyl sulfate
    • Morpholinium, ethyl sulfate
    • SCHEMBL1207771
    • DTXSID4051245
    • QDQHWKZZJJDBND-UHFFFAOYSA-M
    • NSC215231
    • CETYLETHYLMORPHOLINIUM ETHYL SULFATE
    • NS00013441
    • NS00079000
    • N,N-CETYLETHYL MORPHOLINIUM ETHOSULFATE
    • 4-CETYL-4-ETHYLMORPHOLINIUM ETHYL SULFATE
    • 4-ethyl-4-hexadecylmorpholin-4-ium ethyl sulfate
    • N-ETHYL-N-HEXADECYLMORPHOLINIUM ETHYL SULFATE
    • Q27278199
    • 78-21-7

  • Applications

    Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate (1:1) (CAS 78-21-7) is a cationic surfactant commonly used in household cleaners and industrial detergents for wetting, emulsification and dispersion; in textile processing it functions as a softening and conditioning additive; it serves as an emulsifier and pigment-dispersion aid in coatings and inks; it can act as an emulsifier/phase-transfer agent in polymerization and other specialty industrial formulations; and in cosmetics/personal care formulations as a conditioning or cleansing agent. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 377.39
    methanol 235.83
    isopropanol 475.11
    water 0.32
    ethyl acetate 2167.16
    n-propanol 647.33
    acetone 1061.68
    n-butanol 852.05
    acetonitrile 437.38
    DMF 705.18
    toluene 856.57
    isobutanol 705.0
    1,4-dioxane 2148.72
    methyl acetate 1133.09
    THF 2814.83
    2-butanone 1391.81
    n-pentanol 500.37
    sec-butanol 734.98
    n-hexane 490.19
    ethylene glycol 25.15
    NMP 1430.08
    cyclohexane 2796.36
    DMSO 992.42
    n-butyl acetate 2063.93
    n-octanol 444.94
    chloroform 4547.81
    n-propyl acetate 1897.06
    acetic acid 528.27
    dichloromethane 4188.74
    cyclohexanone 3645.42
    propylene glycol 65.36
    isopropyl acetate 1823.09
    DMAc 1296.04
    2-ethoxyethanol 713.38
    isopentanol 887.05
    n-heptane 799.07
    ethyl formate 871.92
    1,2-dichloroethane 2995.94
    n-hexanol 554.51
    2-methoxyethanol 684.63
    isobutyl acetate 1244.23
    tetrachloromethane 1837.39
    n-pentyl acetate 2257.73
    transcutol 2464.02
    n-heptanol 500.09
    ethylbenzene 488.37
    MIBK 1250.68
    2-propoxyethanol 778.5
    tert-butanol 789.91
    MTBE 1473.77
    2-butoxyethanol 882.37
    propionic acid 637.85
    o-xylene 697.45
    formic acid 82.14
    diethyl ether 1937.84
    m-xylene 602.48
    p-xylene 725.18
    chlorobenzene 1120.01
    dimethyl carbonate 318.33
    n-octane 238.42
    formamide 158.98
    cyclopentanone 2414.41
    2-pentanone 1620.29
    anisole 672.14
    cyclopentyl methyl ether 2558.67
    gamma-butyrolactone 2305.71
    1-methoxy-2-propanol 722.7
    pyridine 1506.9
    3-pentanone 1628.9
    furfural 1351.24
    n-dodecane 87.61
    diethylene glycol 251.53
    diisopropyl ether 894.03
    tert-amyl alcohol 943.26
    acetylacetone 1525.75
    n-hexadecane 107.9
    acetophenone 777.93
    methyl propionate 1205.62
    isopentyl acetate 1801.0
    trichloroethylene 3731.42
    n-nonanol 449.94
    cyclohexanol 1764.31
    benzyl alcohol 415.45
    2-ethylhexanol 731.1
    isooctanol 579.35
    dipropyl ether 1999.29
    1,2-dichlorobenzene 1230.13
    ethyl lactate 482.82
    propylene carbonate 1462.78
    n-methylformamide 370.5
    2-pentanol 761.08
    n-pentane 507.38
    1-propoxy-2-propanol 1013.25
    1-methoxy-2-propyl acetate 1348.07
    2-(2-methoxypropoxy) propanol 527.48
    mesitylene 521.52
    ε-caprolactone 3114.58
    p-cymene 558.42
    epichlorohydrin 2662.86
    1,1,1-trichloroethane 3576.96
    2-aminoethanol 103.5
    morpholine-4-carbaldehyde 1331.1
    sulfolane 2419.2
    2,2,4-trimethylpentane 314.89
    2-methyltetrahydrofuran 3071.89
    n-hexyl acetate 1658.99
    isooctane 174.08
    2-(2-butoxyethoxy)ethanol 805.07
    sec-butyl acetate 1558.6
    tert-butyl acetate 1892.92
    decalin 482.16
    glycerin 99.69
    diglyme 2253.28
    acrylic acid 338.42
    isopropyl myristate 578.57
    n-butyric acid 1607.14
    acetyl acetate 1278.55
    di(2-ethylhexyl) phthalate 324.49
    ethyl propionate 1649.53
    nitromethane 1014.37
    1,2-diethoxyethane 2139.04
    benzonitrile 704.37
    trioctyl phosphate 297.75
    1-bromopropane 2366.57
    gamma-valerolactone 2830.17
    n-decanol 294.7
    triethyl phosphate 815.95
    4-methyl-2-pentanol 501.46
    propionitrile 664.59
    vinylene carbonate 1152.52
    1,1,2-trichlorotrifluoroethane 1434.95
    DMS 767.52
    cumene 384.97
    2-octanol 453.4
    2-hexanone 1242.4
    octyl acetate 637.53
    limonene 1095.01
    1,2-dimethoxyethane 1824.14
    ethyl orthosilicate 896.24
    tributyl phosphate 423.86
    diacetone alcohol 1135.04
    N,N-dimethylaniline 501.23
    acrylonitrile 491.0
    aniline 695.38
    1,3-propanediol 321.99
    bromobenzene 1425.91
    dibromomethane 3156.89
    1,1,2,2-tetrachloroethane 3921.7
    2-methyl-cyclohexyl acetate 1129.76
    tetrabutyl urea 540.57
    diisobutyl methanol 617.08
    2-phenylethanol 405.18
    styrene 515.63
    dioctyl adipate 723.91
    dimethyl sulfate 551.74
    ethyl butyrate 2017.35
    methyl lactate 336.35
    butyl lactate 961.06
    diethyl carbonate 1056.61
    propanediol butyl ether 453.88
    triethyl orthoformate 1609.61
    p-tert-butyltoluene 503.66
    methyl 4-tert-butylbenzoate 817.26
    morpholine 2409.73
    tert-butylamine 686.64
    n-dodecanol 217.01
    dimethoxymethane 820.31
    ethylene carbonate 1429.73
    cyrene 477.61
    2-ethoxyethyl acetate 1885.2
    2-ethylhexyl acetate 1659.73
    1,2,4-trichlorobenzene 1347.73
    4-methylpyridine 1358.68
    dibutyl ether 1574.91
    2,6-dimethyl-4-heptanol 617.08
    DEF 1827.91
    dimethyl isosorbide 1058.15
    tetrachloroethylene 2896.0
    eugenol 513.89
    triacetin 1242.7
    span 80 559.99
    1,4-butanediol 121.81
    1,1-dichloroethane 2715.06
    2-methyl-1-pentanol 582.34
    methyl formate 299.14
    2-methyl-1-butanol 875.12
    n-decane 223.82
    butyronitrile 927.89
    3,7-dimethyl-1-octanol 590.27
    1-chlorooctane 694.49
    1-chlorotetradecane 217.74
    n-nonane 238.06
    undecane 127.91
    tert-butylcyclohexane 338.0
    cyclooctane 710.12
    cyclopentanol 1275.79
    tetrahydropyran 4209.1
    tert-amyl methyl ether 1423.87
    2,5,8-trioxanonane 997.18
    1-hexene 740.41
    2-isopropoxyethanol 660.88
    2,2,2-trifluoroethanol 299.47
    methyl butyrate 2090.97

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction