Monosodium phosphate

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  • Identifiers

    CAS number
    7558-80-7

    Molecular formula
    H2NaO4P

    SMILES
    OP(=O)(O)[O-].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 81.22%
    Sour 21.53%
    Clean 17.79%
    Sharp 16.19%
    Pungent 12.94%
    Savory 12.04%
    Alcoholic 11.97%
    Bitter 11.2%
    Milky 11.02%
    Sweaty 10.96%

     

    Flavor
    Odorless 70.53%
    Sour 40.3%
    Vinegar 30.84%
    Pungent 27.04%
    Bland 22.25%
    Acidic 22.06%
    Sharp 21.76%
    Formyl 21.32%
    Soy 20.39%
    Mousy 19.83%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    3.63 (weak acid)

    Molecular weight
    119.977 g/mol

    Melting point expt.

    • Decomposes at 75
    • 200 °C (decomposes)

    Flash point

    • 172.47 ˚C est.

    Solubility expt.

    • 121 g/L
    • Freely soluble in water. Insoluble in ethanol or ether
    • White, hygroscopic crystals. Decomp at 100 °C. Solubility: 94.9 g/100 g water at 25 °C. Insoluble in ethanol. /Sodium dihydrogen phosphate monohydrate/
    • In water, 85 g/100 mL

  • Synonyms

    • 7558-80-7
    • Monosodium phosphate
    • Sodium phosphate monobasic
    • SODIUM DIHYDROGEN PHOSPHATE
    • Sodium dihydrogenorthophosphate
    • Sodium acid phosphate
    • Sodium phosphate, monobasic
    • Sodium primary phosphate
    • Monosodium dihydrogen orthophosphate
    • Acid sodium phosphate
    • Sodium phosphate monobasic anhydrous
    • Monosodium monophosphate
    • sodium dihydrogenphosphate
    • Monosodium phosphate, anhydrous
    • Monobasic sodium phosphate
    • Monosodium orthophosphate
    • Sodium dihydrogen orthophosphate
    • sodium;dihydrogen phosphate
    • Monosodium dihydrogen phosphate
    • Sodium dihydrogen phosphate, anhydrous
    • Sodium phosphate (Na(H2PO4))
    • Sodium biphosphate, anhydrous
    • Sodium orthophosphate monobasic
    • NaH2PO4
    • Sodium phosphate,monobasic
    • MFCD00003527
    • KH7I04HPUU
    • 89140-32-9
    • SODIUM PHOSPHATE, MONOBASIC ANHYDROUS
    • 7632-05-5
    • INS NO.339(I)
    • CHEBI:37585
    • SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS
    • Monosodium dihydrogen monophosphate
    • INS-339(I)
    • Sodium phosphate monobasic, anhydrous
    • Sodium phosphate monobasic (anhydrate)
    • Sodium phosphate monobasic (anhydrous)
    • E-339(I)
    • phosphoric acid, monosodium salt, anhydrous
    • Monosorb XP-4
    • Phosphoric acid, sodium salt
    • Primary sodium phosphate
    • Sodium biphosphate anhydrous
    • Monosodium hydrogen phosphate
    • Sodium phosphate (NaH2PO4)
    • Sodium orthophosphate, primary
    • Sodium dihydrogen monophosphate
    • HSDB 738
    • EINECS 231-449-2
    • UNII-KH7I04HPUU
    • Sodium dihydrogen phosphate (1:2:1)
    • Sodium monobasic phosphate (NaH2PO4)
    • Sodium dihydrogen phosphate (NaH2PO4)
    • Phosphosoda
    • Buromin
    • Clicolon
    • Armite
    • Instant calgon
    • Turrixin ST
    • HY-Phos
    • Hemisodium phosphate
    • Phosphoric acid, sodium salt (1:1)
    • Sodium phosphate glass
    • sodiumdihydrogenphosphate
    • sodium dihydrogenphoshate
    • sodium dihydrogenphospate
    • sodium dihydrogenphosphat
    • sodiumdihydrogen phosphate
    • natriumdihydrogen-phosphate
    • sodium dihydrogen-phosphate
    • sodium phosphate mono-basic
    • EC 231-449-2
    • UNII-SE337SVY37
    • Monosodium phosphate anhydrous
    • sodium dihydrogenphosphate ion
    • Sodium salt of phosphoric acid
    • INKP 100
    • INKP-100
    • SE337SVY37
    • DTXSID7035222
    • Sodium phosphate, monobasic (USP)
    • Anhydrous monobasic sodium phosphate
    • EINECS 231-558-5
    • Sodium dihydrogenphosphate (granular)
    • Phosphoric acid, sodium salt (1:?)
    • AKOS024433265
    • Sodium phosphate monobasic, USP grade
    • AT32901
    • DB09449
    • FS42365
    • SODIUM PHOSPHATE MONOBASIC [HSDB]
    • Sodium phosphate monobasic, AR, >=98%
    • Sodium phosphate monobasic, LR, >=97%
    • SODIUM PHOSPHATE, MONOBASIC [MI]
    • E339
    • SODIUM PHOSPHATE,MONOBASIC [VANDF]
    • DB-221858
    • NS00082818
    • Sodium phosphate monobasic, for HPLC, 99%
    • D04400
    • Sodium phosphate monobasic, BioXtra, >=99.0%
    • Q415877
    • Sodium phosphate monobasic, USP, 98.0-103.0%
    • SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS [II]
    • Sodium phosphate monobasic, ReagentPlus(R), >=99.0%
    • Sodium phosphate monobasic, 99.999% trace metals basis
    • Sodium phosphate monobasic, Vetec(TM) reagent grade, 99%
    • SODIUM PHOSPHATE, MONOBASIC ANHYDROUS [ORANGE BOOK]
    • SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS [ORANGE BOOK]
    • Sodium phosphate monobasic, SAJ first grade, 98.0-101.0%
    • Sodium phosphate monobasic, SAJ special grade, 99.0-101.0%
    • EPA Method 603/8030, VOA Vial Preserved to pH 4 - 5, 72/cs
    • Sodium phosphate monobasic, purum p.a., anhydrous, >=99.0% (T)
    • Sodium phosphate monobasic, meets USP testing specifications, anhydrous
    • Sodium phosphate monobasic, anhydrous, free-flowing, Redi-Dri(TM), >=99.0%
    • Sodium phosphate monobasic, BioReagent, for molecular biology, anhydrous, >=98%
    • Sodium phosphate monobasic, Biotechnology Performance Certified, Cell Culture Tested
    • Sodium phosphate monobasic Molecular Biology Grade, suitable for cell culture, insect cell culture, and plant cell culture
    • Sodium phosphate monobasic, BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99.0% (titration)

  • Applications

    Monosodium phosphate (CAS 7558-80-7) is used across several industries as a buffering agent and acidity regulator, a chelating/softening agent, and a phosphorus source in agriculture and hydroponics. In food processing it serves as a buffering aid and processing aid; in cleaning products it functions as a water-softening builder; in cosmetics and personal care it acts as a pH adjuster and chelating agent; in pharmaceuticals it is employed as a buffering excipient in formulations; and in industrial manufacturing it provides pH control in chemical processes and metal finishing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 546.68
    methanol 1183.64
    isopropanol 407.79
    water 2444.62
    ethyl acetate 39.08
    n-propanol 303.03
    acetone 388.86
    n-butanol 177.61
    acetonitrile 151.4
    DMF 1558.78
    toluene 17.26
    isobutanol 172.52
    1,4-dioxane 203.77
    methyl acetate 80.45
    THF 421.0
    2-butanone 100.18
    n-pentanol 122.32
    sec-butanol 165.68
    n-hexane 14.59
    ethylene glycol 873.57
    NMP 428.74
    cyclohexane 16.27
    DMSO 1016.48
    n-butyl acetate 31.28
    n-octanol 39.62
    chloroform 17.85
    n-propyl acetate 40.22
    acetic acid 254.57
    dichloromethane 29.7
    cyclohexanone 77.28
    propylene glycol 577.94
    isopropyl acetate 33.38
    DMAc 613.12
    2-ethoxyethanol 409.29
    isopentanol 108.11
    n-heptane 14.85
    ethyl formate 88.6
    1,2-dichloroethane 36.44
    n-hexanol 81.73
    2-methoxyethanol 773.45
    isobutyl acetate 24.21
    tetrachloromethane 11.32
    n-pentyl acetate 26.7
    transcutol 196.42
    n-heptanol 57.01
    ethylbenzene 9.61
    MIBK 51.75
    2-propoxyethanol 286.33
    tert-butanol 287.7
    MTBE 68.28
    2-butoxyethanol 161.43
    propionic acid 138.43
    o-xylene 17.42
    formic acid 607.05
    diethyl ether 85.9
    m-xylene 16.75
    p-xylene 12.43
    chlorobenzene 8.2
    dimethyl carbonate 118.8
    n-octane 5.49
    formamide 813.7
    cyclopentanone 162.5
    2-pentanone 79.49
    anisole 36.91
    cyclopentyl methyl ether 102.93
    gamma-butyrolactone 160.04
    1-methoxy-2-propanol 523.29
    pyridine 72.03
    3-pentanone 54.35
    furfural 156.98
    n-dodecane 3.61
    diethylene glycol 434.43
    diisopropyl ether 25.48
    tert-amyl alcohol 128.73
    acetylacetone 86.04
    n-hexadecane 3.7
    acetophenone 36.07
    methyl propionate 75.27
    isopentyl acetate 21.56
    trichloroethylene 25.55
    n-nonanol 34.4
    cyclohexanol 85.24
    benzyl alcohol 58.02
    2-ethylhexanol 29.0
    isooctanol 35.49
    dipropyl ether 59.62
    1,2-dichlorobenzene 8.04
    ethyl lactate 78.42
    propylene carbonate 58.75
    n-methylformamide 698.03
    2-pentanol 104.65
    n-pentane 22.57
    1-propoxy-2-propanol 165.32
    1-methoxy-2-propyl acetate 55.01
    2-(2-methoxypropoxy) propanol 88.6
    mesitylene 15.26
    ε-caprolactone 57.71
    p-cymene 10.27
    epichlorohydrin 127.72
    1,1,1-trichloroethane 15.39
    2-aminoethanol 776.08
    morpholine-4-carbaldehyde 393.07
    sulfolane 211.46
    2,2,4-trimethylpentane 5.5
    2-methyltetrahydrofuran 116.68
    n-hexyl acetate 26.71
    isooctane 5.61
    2-(2-butoxyethoxy)ethanol 131.03
    sec-butyl acetate 21.11
    tert-butyl acetate 37.48
    decalin 4.59
    glycerin 790.36
    diglyme 240.68
    acrylic acid 162.72
    isopropyl myristate 14.78
    n-butyric acid 89.65
    acetyl acetate 25.91
    di(2-ethylhexyl) phthalate 20.92
    ethyl propionate 37.17
    nitromethane 348.19
    1,2-diethoxyethane 49.89
    benzonitrile 27.99
    trioctyl phosphate 20.32
    1-bromopropane 20.33
    gamma-valerolactone 210.37
    n-decanol 26.78
    triethyl phosphate 21.62
    4-methyl-2-pentanol 51.48
    propionitrile 81.3
    vinylene carbonate 54.2
    1,1,2-trichlorotrifluoroethane 143.46
    DMS 30.06
    cumene 9.69
    2-octanol 30.47
    2-hexanone 51.07
    octyl acetate 21.56
    limonene 13.34
    1,2-dimethoxyethane 392.27
    ethyl orthosilicate 22.51
    tributyl phosphate 18.45
    diacetone alcohol 101.43
    N,N-dimethylaniline 49.36
    acrylonitrile 114.19
    aniline 51.1
    1,3-propanediol 488.33
    bromobenzene 5.14
    dibromomethane 18.38
    1,1,2,2-tetrachloroethane 29.55
    2-methyl-cyclohexyl acetate 21.32
    tetrabutyl urea 36.4
    diisobutyl methanol 21.47
    2-phenylethanol 43.86
    styrene 10.4
    dioctyl adipate 23.92
    dimethyl sulfate 166.55
    ethyl butyrate 29.48
    methyl lactate 162.68
    butyl lactate 46.64
    diethyl carbonate 22.04
    propanediol butyl ether 137.93
    triethyl orthoformate 29.6
    p-tert-butyltoluene 11.35
    methyl 4-tert-butylbenzoate 50.41
    morpholine 302.17
    tert-butylamine 149.23
    n-dodecanol 21.47
    dimethoxymethane 590.31
    ethylene carbonate 51.59
    cyrene 109.93
    2-ethoxyethyl acetate 35.41
    2-ethylhexyl acetate 16.21
    1,2,4-trichlorobenzene 10.2
    4-methylpyridine 58.33
    dibutyl ether 20.57
    2,6-dimethyl-4-heptanol 21.47
    DEF 131.81
    dimethyl isosorbide 111.74
    tetrachloroethylene 25.62
    eugenol 77.12
    triacetin 37.15
    span 80 72.08
    1,4-butanediol 287.89
    1,1-dichloroethane 25.13
    2-methyl-1-pentanol 58.55
    methyl formate 442.51
    2-methyl-1-butanol 97.84
    n-decane 5.0
    butyronitrile 68.42
    3,7-dimethyl-1-octanol 22.8
    1-chlorooctane 9.96
    1-chlorotetradecane 5.63
    n-nonane 5.23
    undecane 4.12
    tert-butylcyclohexane 4.37
    cyclooctane 8.41
    cyclopentanol 174.7
    tetrahydropyran 100.66
    tert-amyl methyl ether 49.76
    2,5,8-trioxanonane 183.67
    1-hexene 23.47
    2-isopropoxyethanol 203.03
    2,2,2-trifluoroethanol 205.33
    methyl butyrate 51.43

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction